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ZNF135 Gene

protein-coding   GIFtS: 56
GCID: GC19P058602

Zinc Finger Protein 135

(Previous names: zinc finger protein 61, zinc finger protein 135 (clone pHZ-17))
(Previous symbols: ZNF61, ZNF78L1)
  See ZNF135-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 1351 2     pHZ-172
Zinc Finger Protein 611 2 3     pT32
ZNF611 2 3     Zinc Finger Protein 78-Like 1 (PT3)2
ZNF78L11 2 3     Zinc Finger Protein 78-Like 13
Zinc Finger Protein 135 (Clone PHZ-17)1 2     

External Ids:    HGNC: 129191   Entrez Gene: 76942   Ensembl: ENSG000001762937   OMIM: 6040775   UniProtKB: P527423   

Export aliases for ZNF135 gene to outside databases

Previous GC identifers: GC19P059476 GC19P059025 GC19P063246 GC19P063263 GC19P063060 GC19P063264 GC19P058571 GC19P054881 GC19P058573 GC19P058577 GC19P058587


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZNF135 Gene:
ZNF135 (zinc finger protein 135) is a protein-coding gene. Diseases associated with ZNF135 include renal pelvis carcinoma, and ureteral benign neoplasm. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF334.

UniProtKB/Swiss-Prot: ZN135_HUMAN, P52742
Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. May be involved in
transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF135 gene promoter:
         Elk-1   p53   Pax-2   Pax-2a   AREB6   Pax-2b   HOXA5   ARP-1   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF135 promoter sequence
   Search Chromatin IP Primers for ZNF135

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF135


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.4   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.4

ZNF135 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF135 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P058602:  view genomic region     (about GC identifiers)

Start:
58,570,607 bp from pter      End:
58,597,677 bp from pter
Size:
27,071 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for ZNF135

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZN135_HUMAN, P52742 (See protein sequence)
Recommended Name: Zinc finger protein 135  
Size: 658 amino acids; 75261 Da
Sequence caution: Sequence=AAC50254.1; Type=Frameshift; Positions=207, 558, 563;
Secondary accessions: B4DHH9 E9PEV2 F5GYY9 I3L0B3 Q5U5L3 Q8N1I7
Alternative splicing: 4 isoforms:  P52742-1   P52742-2   P52742-3   P52742-4   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for ZNF135: NX_P52742

Explore proteomics data for ZNF135 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF135 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001157999.1  NP_001158001.1  NP_001158002.1  NP_001276330.1  NP_001276331.1  NP_003427.3  NP_009065.1  

    ENSEMBL proteins: 
     ENSP00000369437   ENSP00000441410   ENSP00000321406   ENSP00000422074   ENSP00000427691  
     ENSP00000471344   ENSP00000444828  
    Reactome Protein details: P52742

    ZNF135 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZNF135

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    4 InterPro protein domains:
     IPR001909 Krueppel-associated_box
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry P52742

    ProtoNet protein and cluster: P52742

    1 Blocks protein domain: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: ZN135_HUMAN, P52742
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 16 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    Find genes that share domains with ZNF135           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN135_HUMAN, P52742
    Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. May be involved in
    transcriptional regulation

         Genatlas biochemistry entry for ZNF135:
    zinc finger protein 135 (C2H2 type,Kruppel-like)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity NAS7557990
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZNF135           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ZNF135:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZNF135
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZNF135
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZNF135

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZNF135:
    hsa-mir-335-5p (MIRT018462)

    Block miRNA regulation of human, mouse, rat ZNF135 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate ZNF135:
    hsa-miR-345 hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidZNF135 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZNF135
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF135

    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF135


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN135_HUMAN, P52742: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    cytoskeleton1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus NAS7557990

    Find genes that share ontologies with ZNF135           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF135 About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with ZNF135           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZNF135
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF135
    Interactions:

        Search GeneGlobe Interaction Network for ZNF135

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    Selected Interacting proteins for ZNF135 (P527422, 3 ENSP000003214064) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ANXA7P200732, 3MINT-8248981 I2D: score=1 
    CDKN1AP389362, 3MINT-8252494 I2D: score=1 
    GADD45AP245222, 3MINT-8256140 I2D: score=1 
    GSK3BP498412, 3MINT-8257856 I2D: score=1 
    RAP1BP612242, 3MINT-8268185 I2D: score=1 
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    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated NAS7557990
    GO:0007010cytoskeleton organization IMP--
    GO:0022604regulation of cell morphogenesis IMP--

    Find genes that share ontologies with ZNF135           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF135 (ZN135)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZNF135 gene (7 alternative transcripts): 
    NM_001164527.1  NM_001164529.1  NM_001164530.1  NM_001289401.1  NM_001289402.1  NM_003436.3  NM_007134.1  

    Unigene Cluster for ZNF135:

    Zinc finger protein 135
    Hs.85863  [show with all ESTs]
    Unigene Representative Sequence: AL157426
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000359978(uc002qrd.2) ENST00000401053(uc010yhq.2 uc010yhr.2 uc021vcu.1 uc002qrg.3)
    ENST00000313434(uc002qre.3) ENST00000511556 ENST00000506786(uc002qrf.3)
    ENST00000515535 ENST00000439855(uc021vct.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZNF135 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate ZNF135:
    hsa-miR-345 hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidZNF135 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZNF135
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF135
    Clone
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    OriGene clones in human, mouse for ZNF135 (see all 26)
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    GenScript: all cDNA clones in your preferred vector (see all 5): ZNF135 (NM_001164529)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF135
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF135
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ZNF135
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF135
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ZNF135
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF135
      QuantiFast Probe-based Assays in human, mouse, rat ZNF135

    Additional mRNA sequence: 

    AK094202.1 AK095796.1 AK098011.1 AK295110.1 AK297226.1 AL157426.1 AL833637.1 BC046434.1 
    BX647775.1 U09413.1 X65231.1 

    21 DOTS entries:

    DT.91775293  DT.100673715  DT.109676  DT.101981444  DT.95273940  DT.95273948  DT.75168482  DT.441381 
    DT.121438340  DT.121438298  DT.100000454  DT.99936969  DT.121438333  DT.107819  DT.121304337  DT.97777811 
    DT.121438337  DT.121438349  DT.95321894  DT.95364045  DT.99962472 

    Selected AceView cDNA sequences (see all 67):

    AA436237 BM683265 BG678919 BX118276 BM993886 CB851264 BX454973 AI333583 
    BP368295 BX642404 BE696848 AK098011 AK094202 AI684767 AV654106 CN479421 
    BX396595 BX471484 NM_003436 BX642405 CA450496 BF347790 AL833637 BM929266 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF135 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGAAACTCC
    ZNF135 Expression
    About this image


    ZNF135 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    ZNF135 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF135 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.85863
        Custom PCR Arrays for ZNF135
    Primer
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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      --

    ENSEMBL Gene Tree for ZNF135 (if available)
    TreeFam Gene Tree for ZNF135 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF135 gene
    ZNF3342  ZNF4202  ZNF780A2  ZNF6652  ZNF72  ZNF232  ZNF33A2  RBAK2  
    ZNF7172  ZNF302  ZNF5732  ZNF33B2  ZNF5402  ZNF2512  ZNF6052  ZNF842  
    ZNF1892  ZNF5712  ZNF6302  ZNF3372  ZNF2832  ZNF4042  ZNF4842  ZNF122  
    ZNF3452  ZNF1842  ZNF6992  ZNF412  ZNF6152  ZNF4702  ZNF5692  
    Selected SIMAP similar genes for ZNF135 using alignment to 3 protein entries:     ZN135_HUMAN (see all proteins) (see all similar genes):
    ZNF78L1    ZNF818P    DKFZp313M0722    ZNF323    ZNF625-ZNF20    ZSCAN31
    ZFP41    DKFZp686H10254    ZNF436    ZNF852    ZSCAN16    ZSCAN21
    DKFZp666C237    HZF36    ZFS-1    ZFS-6    ZNF146    ZNF167

    Find genes that share paralogs with ZNF135           About GenesLikeMe


    5 Pseudogenes.org Pseudogenes for ZNF135
    PGOHUM00000256878 PGOHUM00000256899 PGOHUM00000240826 PGOHUM00000233477 PGOHUM00000257273


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF135 (see all 377)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2017244431,2
    --58568630(+) AAAGA-/TTTTTT 5 -- us2k10--------
    rs1923882911,2
    C--58568639(+) TTTTTA/TAAAGG 5 -- us2k10--------
    rs1492313871,2
    --58568814(+) ATGGTC/GGGGGG 5 -- us2k10--------
    rs1147029691,2
    C,F--58568884(+) AGCCAA/GGAAGG 5 -- us2k11Minor allele frequency- G:0.01WA 118
    rs116674821,2
    C,F,A,H--58568958(+) GGCACT/CGGAGT 5 -- us2k116Minor allele frequency- C:0.50NS NA WA CSA EA 608
    rs1843993771,2
    --58568995(+) GTAGAA/GTGTTA 5 -- us2k10--------
    rs9741831,2
    C,F,H--58569118(-) GGGTCG/CTGCGG 5 -- us2k114Minor allele frequency- C:0.35EA NS NA WA 862
    rs730718741,2
    C,F--58569169(+) AGCCCG/ACCCCT 5 -- us2k11Minor allele frequency- A:0.02NA 120
    rs1424534971,2
    --58569176(+) CCCTGA/CAAAAG 5 -- us2k10--------
    rs1896879771,2
    --58569190(+) GTACGA/GTTTAG 5 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZNF135 (58570607 - 58597677 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ZNF135:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv912533CNV Loss21882294
    nsv912535CNV Loss21882294
    nsv912534CNV Loss21882294
    nsv833885CNV Loss17160897
    nsv828656CNV Gain20364138
    nsv458836CNV Gain19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF135
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF135

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604077    OMIM disorders: --

    2 diseases for ZNF135:    
    About MalaCards
    renal pelvis carcinoma    ureteral benign neoplasm

    9 diseases from the University of Copenhagen DISEASES database for ZNF135:
    Carcinoma     Prostate cancer     Urinary bladder cancer     Renal cell carcinoma
    Ureteral benign neoplasm     Gallbladder cancer     Colorectal cancer     Renal pelvis carcinoma
    Esophageal cancer

    Find genes that share disorders with ZNF135           About GenesLikeMe

    Genetic Association Database (GAD): ZNF135

    Export disorders for ZNF135 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF135 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with ZNF135)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders. (PubMed id 7557990)1, 2, 3 Tommerup N. and Vissing H. (Genomics 1995)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PubMed id 1505991)1, 3 Lichter P.... Ward D.C. (Genomics 1992)
    4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    5. Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. (PubMed id 21834987)2 Bai S.W.... Ridley A.J. (BMC Biol. 2011)
    6. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    7. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (BMC Med. Genet. 2007)
    8. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PubMed id 17903292)4 Hwang S.J....Fox C.S. (BMC Med. Genet. 2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7694 HGNC: 12919 AceView: ZNF135 Ensembl:ENSG00000176293 euGenes: HUgn7694
    ECgene: ZNF135 H-InvDB: ZNF135

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZNF135 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZNF135 gene:
    Search GeneIP for patents involving ZNF135

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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