Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF135 Gene

protein-coding   GIFtS: 55
GCID: GC19P058577

zinc finger protein 135

(Previous names: zinc finger protein 61, zinc finger protein 135 (clone...)
(Previous symbols: ZNF61, ZNF78L1)
 Explore 12 diseases affiliated with
ZNF135 via our new
 Human Malady Compendium 
Biological research products
for ZNF135
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Zinc Finger Protein 1351 2     Zinc Finger Protein 135 (Clone PHZ-17)1 2
Zinc Finger Protein 611 2 3     PT31
ZNF611 2 3     Zinc Finger Protein 78-Like 1 (PT3)2
ZNF78L11 2 3     Zinc Finger Protein 78-Like 13
PHZ-171     

External Ids:    HGNC: 129191   Entrez Gene: 76942   Ensembl: ENSG000001762937   OMIM: 6040775   UniProtKB: P527423   
ORGUL members:         
NONCODE:n338971    

Export aliases for ZNF135 gene to outside databases

Previous GC identifers: GC19P059476 GC19P059025 GC19P063246 GC19P063263 GC19P063060 GC19P063264 GC19P058571 GC19P054881 GC19P058573


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZN135_HUMAN, P52742
Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. May be involved in
transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF135 gene promoter:
         Elk-1   p53   Pax-2   Pax-2a   AREB6   Pax-2b   HOXA5   ARP-1   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF135 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF135

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF135


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.4   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.4

ZNF135 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF135 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P058577:  view genomic region     (about GC identifiers)

Start:
58,570,607 bp from pter      End:
58,597,677 bp from pter
Size:
27,071 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ZN135_HUMAN, P52742 (See protein sequence)
Recommended Name: Zinc finger protein 135  
Size: 658 amino acids; 75261 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=AAC50254.1; Type=Frameshift; Positions=207, 558, 563;
Secondary accessions: I3L0B3 Q5U5L3 Q8N1I7
Alternative splicing: 2 isoforms:  P52742-1   P52742-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZNF135: NX_P52742

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P52742

  • ZNF135 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (5 alternative transcripts): 
    NP_001157999.1  NP_001158001.1  NP_001158002.1  NP_003427.3  NP_009065.1  

    ENSEMBL proteins: 
     ENSP00000425734   ENSP00000321406   ENSP00000375580   ENSP00000422074   ENSP00000427691  
     ENSP00000441410   ENSP00000369437   ENSP00000444828  
    Reactome Protein details: P52742
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for ZNF135 
    GenScript Custom Purified and Recombinant Proteins Services for ZNF135
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ZNF135

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus NAS7557990


    ZNF135 for ontologies           About GeneDecksing



    ZNF135 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZNF135 
    GenScript Custom Superior Antibodies Services for ZNF135
    Novus Biologicals ZNF135 Antibody
    Search for Antibodies for ZNF135 at Abcam  
    Uscn Antibodies for ZNF135
    Search ThermoFisher Antibodies for ZNF135

    Assay Products for ZNF135: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZNF135
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for ZNF135


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ZNF135 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR015880 Znf_C2H2-like
     IPR001909 Krueppel-associated_box
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry P52742

    ProtoNet protein and cluster: P52742

    1 Blocks protein family: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: ZN135_HUMAN, P52742
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 16 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ZN135_HUMAN, P52742
    Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. May be involved in
    transcriptional regulation

         Genatlas biochemistry entry for ZNF135:
    zinc finger protein 135 (C2H2 type,Kruppel-like)

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 5): ZNF135
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF135
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF135:
    hsa-miR-345 hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidZNF135 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF135
    OriGene shRNA RFP: ZNF135
    OriGene siRNA: ZNF135
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF135

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZNF135

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF135 (see all 6)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF135 (see all 6)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 5): ZNF135 (NM_001164529)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF135
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF135 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZNF135
    Search LifeMap BioReagents cell lines for ZNF135

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF135

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity NAS7557990
    GO:0008270zinc ion binding IEA--


    ZNF135 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for ZNF135:
     Increased G1 DNA content 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Generic Transcription Pathway
    Generic Transcription Pathway1.00
    Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2        Reactome Pathways for ZNF135
        Generic Transcription Pathway
    Gene Expression



    ZNF135 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF135

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5/7 Interacting proteins for ZNF135 (P527422, 3 ENSP000003214064) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ANXA7P200732, 3MINT-8248981 I2D: score=1 
    CDKN1AP389362, 3MINT-8252494 I2D: score=1 
    GADD45AP245222, 3MINT-8256140 I2D: score=1 
    GSK3BP498412, 3MINT-8257856 I2D: score=1 
    RAP1BP612242, 3MINT-8268185 I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent NAS7557990
    GO:0007010cytoskeleton organization IMP--
    GO:0022604regulation of cell morphogenesis IMP--


    ZNF135 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF135
    Search CenterWatch for drugs/clinical trials and news about ZNF135 / ZN135 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZNF135 gene (5 alternative transcripts): 
    NM_001164527.1  NM_001164529.1  NM_001164530.1  NM_003436.3  NM_007134.1  

    Unigene Cluster for ZNF135:

    Zinc finger protein 135
    Hs.85863  [show with all ESTs]
    Unigene Representative Sequence: AL157426
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000504540 ENST00000313434(uc002qre.3) ENST00000391699 ENST00000511556
    ENST00000506786(uc002qrf.3) ENST00000515535 ENST00000401053(uc010yhq.2 uc010yhr.2 uc021vcu.1 uc002qrg.3)
    ENST00000359978(uc002qrd.2) ENST00000439855(uc021vct.1)

    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 5): ZNF135
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF135
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF135:
    hsa-miR-345 hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidZNF135 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF135
    OriGene shRNA RFP: ZNF135
    OriGene siRNA: ZNF135
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF135
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF135 (see all 6)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF135 (see all 6)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 5): ZNF135 (NM_001164529)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF135
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF135 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF135
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF135
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF135
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF135

    Additional cDNA sequence: 

    AK094202.1 AK095796.1 AK098011.1 AK295110.1 AK297226.1 AL157426.1 AL833637.1 BC046434.1 
    BX647775.1 U09413.1 X65231.1 

    17 DOTS entries:

    DT.109676  DT.100673715  DT.101981444  DT.121438340  DT.121438298  DT.100000454  DT.99936969  DT.75168482 
    DT.121438333  DT.91775293  DT.107819  DT.121304337  DT.97777811  DT.121438349  DT.95321894  DT.95364045 
    DT.99962472 

    24/67 AceView cDNA sequences (see all 67):

    BG678919 AA436237 BM683265 CA432999 AV654106 BP368295 BM993886 BE696848 
    BX118276 AK095796 BX454973 BX396595 AI333583 AK094202 AA436236 AW771439 
    BX647775 AI288798 CB108603 AL833637 N67262 BE467257 CN479421 AK098011 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF135 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGGAAACTCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    ZNF135 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ mesenchymal progenitor SM30 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See ZNF135 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF135

    SOURCE GeneReport for Unigene cluster: Hs.85863
        SABiosciences Custom PCR Arrays for ZNF135
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF135
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF135
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF135
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF135
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF135

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ZNF135 gene from 2/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia ZNF7746
    --
    (see all 6)
    --
    57(a)
    54(a)
    (see all 6)
    possible ortholog
    1 ↔ many
    (see all 6)
    2(199167583-199168815)
    GL343220.1(2330463-2336819)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG122993   -- 41(a)
    (best of 6)
      32A4   --


    ENSEMBL Gene Tree for ZNF135 (if available)
    TreeFam Gene Tree for ZNF135 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF135 gene
    ZNF5702  ZNF2872  ZNF1812  ZFP282  ZNF4712  ZNF72  ZNF2502  ZNF8792  
    ZNF3022  ZNF354C2  ZNF742  ZNF5832  ZFP902  ZNF1892  ZNF354A2  ZNF354B2  
    ZNF5682  ZNF342  ZNF5272  ZNF82  ZNF5692  ZNF4702  
    18/543 SIMAP similar genes for ZNF135 using alignment to 7 protein entries:     ZN135_HUMAN (see all proteins) (see all similar genes):
    ZNF78L1    ZNF818P    ZNF323    ZFS-1    ZFP41    ZNF826P
    DKFZp313M0722    HZF36    ZNF501    ZNF56    ZNF146    DKFZp666C237
    ZNF167    ZKSCAN7    ZSCAN23    ZFS-4    ZSCAN21    DKFZp686H10254

    ZNF135 for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for ZNF135
    PGOHUM00000256878 PGOHUM00000256899 PGOHUM00000240826 PGOHUM00000233477 PGOHUM00000257273


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/303 NCBI SNPs in ZNF135 are shown (see all 303    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2017244431,2
    --58568630(+) AAAGA-/TTTTTT 5 -- us2k10--------
    rs1923882911,2
    --58568639(+) TTTTTA/TAAAGG 5 -- us2k10--------
    rs1492313871,2
    --58568814(+) ATGGTC/GGGGGG 5 -- us2k10--------
    rs1147029691,2
    --58568884(+) AGCCAA/GGAAGG 5 -- us2k11Minor allele frequency- G:0.01WA 118
    rs116674821,2
    C,F,A,H,--58568958(+) GGCACT/CGGAGT 5 -- us2k116Minor allele frequency- C:0.50NS NA WA CSA EA 608
    rs1843993771,2
    --58568995(+) GTAGAA/GTGTTA 5 -- us2k10--------
    rs9741831,2
    C,F,H,--58569118(-) GGGTCG/CTGCGG 5 -- us2k114Minor allele frequency- C:0.35EA NS NA WA 862
    rs730718741,2
    C,F,--58569169(+) AGCCCG/ACCCCT 5 -- us2k11Minor allele frequency- A:0.02NA 120
    rs1424534971,2
    --58569176(+) CCCTGA/CAAAAG 5 -- us2k10--------
    rs1896879771,2
    --58569190(+) GTACGA/GTTTAG 5 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZNF135 (58570607 - 58597677 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ZNF135
         1 CNV: 5118

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF135
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF135

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ZNF135 for disorders           About GeneDecksing

    OMIM gene information: 604077    OMIM disorders: --

    12 diseases for ZNF135:    About MalaCards
    subglottis carcinoma    ureteral neoplasm    glottis carcinoma    ureter carcinoma
    urinary bladder cancer    hydronephrosis    gallbladder cancer    esophageal cancer
    thyroid cancer    carcinoma    esophagitis    thyroiditis

    9 diseases from the University of Copenhagen DISEASES database for ZNF135:
    Carcinoma     Prostate cancer     Urinary bladder cancer     Renal cell carcinoma
    Gallbladder cancer     Ureteral benign neoplasm     Colorectal cancer     Renal pelvis carcinoma
    Esophageal cancer

    Export disorders for ZNF135 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF135 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with ZNF135)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders. (PubMed id 7557990)1, 2, 3 Tommerup N. and Vissing H. (1995)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PubMed id 1505991)1, 3 Lichter P....Ward D.C. (1992)
    4. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    5. Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. (PubMed id 21834987)2 Bai S.W.... Ridley A.J. (2011)
    6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
    10. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7694 HGNC: 12919 AceView: ZNF135 Ensembl:ENSG00000176293 euGenes: HUgn7694
    ECgene: ZNF135 H-InvDB: ZNF135

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF135 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZNF135 gene:
    Search GeneIP for patents involving ZNF135

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for ZNF135  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF135   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF135  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for ZNF135   OriGene 3'-UTR Clone for ZNF135  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF135   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF135  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZNF135   OriGene Custom Protein Services for ZNF135  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF135
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF135
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF135
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF135
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF135
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF135
     GenScript Custom Purified and Recombinant Proteins Services for ZNF135 GenScript cDNA clones with any tag delivered in your preferred vector for ZNF135
     GenScript Custom Assay Services for ZNF135 GenScript Custom Superior Antibodies Services for ZNF135
     GenScript Custom overexpressing Cell Line Services for ZNF135 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ZNF135 promoter
     Search Chromatin IP Primers for ZNF135
     RT2 qPCR Primer Assay in human, mouse / rat ZNF135
     Search GNC Networks for ZNF135
     SABiosciences Custom PCR Arrays for ZNF135
     Search Tocris compounds for ZNF135
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ZNF135 antibodies
     Search for Antibodies for ZNF135 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ZNF135
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     ZNF135 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for ZNF135
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF135
     SwitchGear 3'UTR luciferase reporter plasmids for ZNF135
     SwitchGear Promoter luciferase reporter plasmids for ZNF135
     Search ThermoFisher Antibodies for ZNF135
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF135
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZNF135 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4