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Aliases for ZNF134 Gene

Aliases for ZNF134 Gene

  • Zinc Finger Protein 134 2 3 5
  • Zinc Finger Protein 134 (Clone PHZ-15) 2 3
  • PHZ-15 3

External Ids for ZNF134 Gene

Previous GeneCards Identifiers for ZNF134 Gene

  • GC19P059024
  • GC19P058579
  • GC19P062801
  • GC19P062817
  • GC19P058126
  • GC19P054438

Summaries for ZNF134 Gene

GeneCards Summary for ZNF134 Gene

ZNF134 (Zinc Finger Protein 134) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF134 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF134 Gene

Genomics for ZNF134 Gene

Regulatory Elements for ZNF134 Gene

Enhancers for ZNF134 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF134 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF134 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF134 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF134 Gene

Chromosome:
19
Start:
57,614,233 bp from pter
End:
57,624,723 bp from pter
Size:
10,491 bases
Orientation:
Plus strand

Genomic View for ZNF134 Gene

Genes around ZNF134 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF134 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF134 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF134 Gene

Proteins for ZNF134 Gene

  • Protein details for ZNF134 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P52741-ZN134_HUMAN
    Recommended name:
    Zinc finger protein 134
    Protein Accession:
    P52741
    Secondary Accessions:
    • Q9Y4B2

    Protein attributes for ZNF134 Gene

    Size:
    427 amino acids
    Molecular mass:
    48480 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF134 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF134 Gene

Proteomics data for ZNF134 Gene at MOPED

Post-translational modifications for ZNF134 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF134 Gene

No data available for DME Specific Peptides for ZNF134 Gene

Domains & Families for ZNF134 Gene

Gene Families for ZNF134 Gene

Protein Domains for ZNF134 Gene

Suggested Antigen Peptide Sequences for ZNF134 Gene

Graphical View of Domain Structure for InterPro Entry

P52741

UniProtKB/Swiss-Prot:

ZN134_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF134: view

Function for ZNF134 Gene

Molecular function for ZNF134 Gene

GENATLAS Biochemistry:
zinc finger protein 134 (C2H2 type,Kruppel-like),tightly linked to a full size LTR of human endogenous retroviruses HERV-K
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF134: view

Animal Model Products

CRISPR Products

miRNA for ZNF134 Gene

miRTarBase miRNAs that target ZNF134

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF134 Gene

Localization for ZNF134 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF134 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF134 Gene COMPARTMENTS Subcellular localization image for ZNF134 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF134 Gene

Pathways & Interactions for ZNF134 Gene

SuperPathways for ZNF134 Gene

No Data Available

Interacting Proteins for ZNF134 Gene

Gene Ontology (GO) - Biological Process for ZNF134 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF134 Gene

Drugs & Compounds for ZNF134 Gene

No Compound Related Data Available

Transcripts for ZNF134 Gene

Unigene Clusters for ZNF134 Gene

Zinc finger protein 134:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF134 Gene

No ASD Table

Relevant External Links for ZNF134 Gene

GeneLoc Exon Structure for
ZNF134
ECgene alternative splicing isoforms for
ZNF134

Expression for ZNF134 Gene

mRNA expression in normal human tissues for ZNF134 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF134 Gene



SOURCE GeneReport for Unigene cluster for ZNF134 Gene Hs.469694

genes like me logo Genes that share expression patterns with ZNF134: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF134 Gene

Orthologs for ZNF134 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF134 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF134 35
  • 84.78 (n)
  • 81.25 (a)
ZNF134 36
  • 68 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF134 35
  • 86.62 (n)
  • 83.14 (a)
ZNF134 36
  • 83 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF134 35
  • 99.45 (n)
  • 99.3 (a)
ZNF134 36
  • 84 (a)
OneToOne
Species with no ortholog for ZNF134:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF134 Gene

ENSEMBL:
Gene Tree for ZNF134 (if available)
TreeFam:
Gene Tree for ZNF134 (if available)

Paralogs for ZNF134 Gene

(498) SIMAP similar genes for ZNF134 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for ZNF134 Gene

genes like me logo Genes that share paralogs with ZNF134: view

Variants for ZNF134 Gene

Sequence variations from dbSNP and Humsavar for ZNF134 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10414451 - 57,620,208(+) GAGCA(C/T)TTCTA reference, missense
rs10413455 - 57,620,255(+) TGCCC(A/G/T)CACAG reference, missense
rs34034473 - 57,620,738(+) AGTGC(A/C/T)GCGAA reference, missense
rs1042102 -- 57,621,728(+) TGGAT(A/C)TGACC utr-variant-3-prime
rs73062592 -- 57,616,608(+) GAGCC(A/G)GCACT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF134 Gene

Variant ID Type Subtype PubMed ID
dgv4028n71 CNV Loss 21882294

Variation tolerance for ZNF134 Gene

Residual Variation Intolerance Score: 88.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.18; 61.78% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF134 Gene

Disorders for ZNF134 Gene

Relevant External Links for ZNF134

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF134

No disorders were found for ZNF134 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF134 Gene

Publications for ZNF134 Gene

  1. Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders. (PMID: 7557990) Tommerup N. … Vissing H. (Genomics 1995) 2 3 4 67
  2. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF134 Gene

Sources for ZNF134 Gene

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