Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF133 Gene

protein-coding   GIFtS: 60
GCID: GC20P018264

zinc finger protein 133

(Previous names: zinc finger protein 150 (pHZ-66), zinc finger protein 133...)
(Previous symbol: ZNF150)
 Explore 3 diseases affiliated with
ZNF133 via our new
 Human Malady Compendium 
Biological research products
for ZNF133
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Zinc Finger Protein 1331 2     Zinc Finger Protein 150 (PHZ-66)1 2
ZNF1501 2 3     Zinc Finger Protein 1503
PHZ-131     EC 2.1.18
PHZ-661     EC 2.1.1.438
Zinc Finger Protein 133 (Clone PHZ-13)1 2     

External Ids:    HGNC: 129171   Entrez Gene: 76922   Ensembl: ENSG000001258467   OMIM: 6040755   UniProtKB: P527363   

Export aliases for ZNF133 gene to outside databases

Previous GC identifers: GC20P018257 GC20P018217


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZN133_HUMAN, P52736
Function: May be involved in transcriptional regulation as a repressor

Gene Wiki entry for ZNF133


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011387.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF133 gene promoter:
         COUP-TF1   ATF-2   Lmo2   COUP   CUTL1   HNF-4alpha2   HNF-4alpha1   COUP-TF   c-Jun   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF133 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF133

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF133


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p11.23   Ensembl cytogenetic band:  20p11.23   HGNC cytogenetic band: 20p11.23

ZNF133 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF133 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P018264:  view genomic region     (about GC identifiers)

Start:
18,269,121 bp from pter      End:
18,297,640 bp from pter
Size:
28,520 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ZN133_HUMAN, P52736 (See protein sequence)
Recommended Name: Zinc finger protein 133  
Size: 654 amino acids; 73388 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: A8K5S4 Q53XU1 Q5JXV8 Q9BUV2 Q9H443
Alternative splicing: 2 isoforms:  P52736-1   P52736-2   

Explore the universe of human proteins at neXtProt for ZNF133: NX_P52736

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P52736

  • 2 DME Specific Peptides for ZNF133 (P52736)
     LSFSKMT  CRECGRGF 

    ZNF133 Protein expression data from MOPED and PaxDb:    About this image 
    ZNF133 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001076799.1  NP_003425.2  

    ENSEMBL proteins: 
     ENSP00000366899   ENSP00000353105   ENSP00000403835   ENSP00000346090   ENSP00000406638  
     ENSP00000400897   ENSP00000383945   ENSP00000385279   ENSP00000442978   ENSP00000439427  
    Reactome Protein details: P52736
    Human Recombinant Protein Products for ZNF133: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate (see all 3): ZNF133
    OriGene Custom Protein Services for ZNF133 
    GenScript Custom Purified and Recombinant Proteins Services for ZNF133
    Novus Biologicals ZNF133 Proteins
    Novus Biologicals ZNF133 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ZNF133

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    ZNF133 for ontologies           About GeneDecksing



    ZNF133 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZNF133 
    GenScript Custom Superior Antibodies Services for ZNF133
    Novus Biologicals ZNF133 Antibodies
    Search for Antibodies for ZNF133 at Abcam  
    Uscn Antibodies for ZNF133
    Search ThermoFisher Antibodies for ZNF133

    Assay Products for ZNF133: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZNF133
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for ZNF133


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ZNF133 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR015880 Znf_C2H2-like
     IPR001909 Krueppel-associated_box
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry P52736

    ProtoNet protein and cluster: P52736

    2 Blocks protein families:
    IPB001909 KRAB box
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZN133_HUMAN, P52736
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 15 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN133_HUMAN, P52736
    Function: May be involved in transcriptional regulation as a repressor

         Genatlas biochemistry entry for ZNF133:
    zinc finger protein 133 (C2H2 type,Kruppel-like,KRAB subfamily)

         Enzyme Numbers (IUBMB): EC 2.1.1.432 EC 2.1.12

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS9278146
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
         
    ZNF133 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZNF133:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for ZNF133 

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 2): ZNF133
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF133
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ZNF133
    SwitchGear 3'UTR luciferase reporter plasmidZNF133 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF133
    OriGene shRNA RFP: ZNF133
    OriGene siRNA: ZNF133
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF133
    Sirion Biotech Custom design and validation of potent shRNA sequences against ZNF133 

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZNF133
    Sirion Biotech Customized adenovirus for overexpression of ZNF133 
    Sirion Biotech Customized adenovirus for potent knockdown of ZNF133

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF133 (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF133 (see all 2)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): ZNF133 (NM_003434)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF133
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF133 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZNF133
    Search LifeMap BioReagents cell lines for ZNF133
    Sirion Biotech Customized stable knockdown cell line services for ZNF133 
    Sirion Biotech Customized inducible knockdown cell line services for ZNF133
    Sirion Biotech Customized stable overexpressing cell line services for ZNF133
    Sirion Biotech Customized inducible overexpressing cell line services for ZNF133

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF133


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Generic Transcription Pathway
    Generic Transcription Pathway1.00
    Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2        Reactome Pathways for ZNF133
        Generic Transcription Pathway
    Gene Expression



    ZNF133 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ZNF133

    5 Interacting proteins for ZNF133 (P527361, 2, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ILKQ134182, 3MINT-8258679 I2D: score=2 
    MAPK6Q166592, 3MINT-8262209 I2D: score=2 
    PDPK1O155302, 3MINT-8265676 I2D: score=2 
    FOSP011001, 3EBI-2687350,EBI-852851 I2D: score=1 
    MDM2Q009873I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----

    ZNF133 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF133
    Search CenterWatch for drugs/clinical trials and news about ZNF133 / ZN133 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZNF133 gene (2 alternative transcripts): 
    NM_001083330.1  NM_003434.4  

    Unigene Cluster for ZNF133:

    Zinc finger protein 133
    Hs.472221  [show with all ESTs]
    Unigene Representative Sequence: NM_003434
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377671(uc010gcq.2 uc010zrv.1 uc010gcr.2 uc010zrx.1 uc002wql.4 uc010gcs.3 uc010zry.2)
    ENST00000360010 ENST00000434018 ENST00000316358(uc002wqm.2) ENST00000425686
    ENST00000462170 ENST00000396026 ENST00000401790 ENST00000402618(uc010zrw.1)
    ENST00000538547 ENST00000535822

    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 2): ZNF133
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF133
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ZNF133
    SwitchGear 3'UTR luciferase reporter plasmidZNF133 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF133
    OriGene shRNA RFP: ZNF133
    OriGene siRNA: ZNF133
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF133
    Sirion Biotech Custom design and validation of potent shRNA sequences against ZNF133 
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF133 (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF133 (see all 2)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): ZNF133 (NM_003434)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF133
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF133 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF133
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF133
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF133
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF133

    Additional cDNA sequence: 

    AK291389.1 AK294263.1 AK295273.1 AK295513.1 AK313525.1 AK316386.1 BC001887.1 BT007310.1 

    9 DOTS entries:

    DT.415476  DT.100028665  DT.97787228  DT.100814687  DT.120836630  DT.120836638  DT.120836653  DT.120836659 
    DT.95196365 

    24/77 AceView cDNA sequences (see all 77):

    AW055275 BX280381 BU742160 CB152052 AA341469 CB152672 BE264198 BM717951 
    W81622 NM_003434 AA594234 AA779084 AA130195 AV682748 BG419708 AA643895 
    AK123005 AL691673 BQ017389 BM801793 BE887288 T09047 BP376077 AL120716 

    GeneLoc Exon Structure

    5/16 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF133 (see all 16)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d
    SP1:                                                              -                                                                           
    SP2:              -     -     -     -     -     -     -     -                                                     -                           
    SP3:              -     -     -     -     -     -     -     -     -                                               -                           
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for ZNF133

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF133 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTTGTGGCC
    ZNF133 Expression
    About this image

    ZNF133 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Yolk SacDefinitive Yolk SacDefinitive Hematopoietic Stem CellsBlood
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See ZNF133 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF133

    SOURCE GeneReport for Unigene cluster: Hs.472221

    UniProtKB/Swiss-Prot: ZN133_HUMAN, P52736
    Tissue specificity: Seems ubiquitous. Seen in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and
    pancreas

        SABiosciences Custom PCR Arrays for ZNF133
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF133
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF133
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF133
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF133
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF133

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for ZNF133 (if available)
    TreeFam Gene Tree for ZNF133 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF133 gene
    ZNF5892  ZNF1692  ZNF3432  ZNF3372  HKR12  
    18/545 SIMAP similar genes for ZNF133 using alignment to 8 protein entries:     ZN133_HUMAN (see all proteins) (see all similar genes):
    POM121C    kr-znf3    MGC12518    ZNF300P1    PRMD9    ZNF78L1
    ZFP41    ZNF696    PRDM9    FLJ00301    ZNF624    ZNF569
    ZNF84    HZF16    ZFS-2    ZFP90    ZNF761    ZNF273

    ZNF133 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/524 NCBI SNPs in ZNF133 are shown (see all 524    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1449535431,2
    C,Fother18296080(+) GGGAAC/TCCTGA 4 N syn11Minor allele frequency- T:0.00NA 4448
    rs1170039711,2
    F--18267135(+) TGCATG/TTTTTT 2 -- us2k11Minor allele frequency- T:0.02NA 120
    rs1825072981,2
    --18267162(+) ATGATC/TTACCG 2 -- us2k10--------
    rs1883031151,2
    --18267166(+) TCTACC/TGAGGT 2 -- us2k10--------
    rs1928402781,2
    --18267173(+) AGGTAC/TATGGT 2 -- us2k10--------
    rs9102471,2
    C,A,H--18267253(-) AAGATA/GTTGTG 2 -- us2k113Minor allele frequency- G:0.01NA WA CSA EA 376
    rs9102461,2
    C,H--18267363(-) CTTGGG/AAGCTT 2 -- us2k113Minor allele frequency- A:0.01NA WA CSA EA 376
    rs1495098411,2
    --18267431(+) TTTCAC/TGAAAG 2 -- us2k10--------
    rs1145255981,2
    F--18267460(+) TTGAAG/AGACCA 2 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1431477101,2
    --18267481(+) GAGGAC/GCTAAG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZNF133 (18269121 - 18297640 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for ZNF133
         2 CNVs: 8883 3213

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF133
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF133

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ZNF133 for disorders           About GeneDecksing

    OMIM gene information: 604075    OMIM disorders: --

    3 diseases for ZNF133:    About MalaCards
    alagille syndrome    chondroblastoma    alcoholism

    2 diseases from the University of Copenhagen DISEASES database for ZNF133:
    Osteoblastoma     Chondroblastoma

    Export disorders for ZNF133 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF133 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with ZNF133)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders. (PubMed id 7557990)1, 2, 3 Tommerup N. and Vissing H. (1995)
    2. Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins. (PubMed id 7649249)1, 2, 3 Vissing H.... Thiesen H.-J. (1995)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    5. PIAS1 interacts with the KRAB zinc finger protein, ZNF133, via zinc finger motifs and regulates its transcriptional activity. (PubMed id 17934332)1, 9 Lee S.J....Hahn M.J. (2007)
    6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    10. Human alcoholism studies of genes identified through mouse quantitative trait locus analysis. (PubMed id 14578011)1 Ehringer M.A....Sikela J.M. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7692 HGNC: 12917 AceView: ZNF133 Ensembl:ENSG00000125846 euGenes: HUgn7692
    ECgene: ZNF133 H-InvDB: ZNF133

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF133 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZNF133 gene:
    Search GeneIP for patents involving ZNF133

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for ZNF133  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF133   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF133  
     OriGene Protein Over-expression Lysate for ZNF133   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for ZNF133   OriGene 3'-UTR Clone for ZNF133  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF133   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF133  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZNF133   OriGene Custom Protein Services for ZNF133  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF133
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF133
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF133
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF133
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF133
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF133
     GenScript Custom Purified and Recombinant Proteins Services for ZNF133 GenScript cDNA clones with any tag delivered in your preferred vector for ZNF133
     GenScript Custom Assay Services for ZNF133 GenScript Custom Superior Antibodies Services for ZNF133
     GenScript Custom overexpressing Cell Line Services for ZNF133 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ZNF133 promoter
     Search Chromatin IP Primers for ZNF133
     RT2 qPCR Primer Assay in human, mouse / rat ZNF133
     GNC Network for ZNF133
     SABiosciences Custom PCR Arrays for ZNF133
     Search Tocris compounds for ZNF133
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ZNF133 antibodies
     ZNF133 proteins
     ZNF133 lysates
     Search for Antibodies for ZNF133 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ZNF133
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     ZNF133 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for ZNF133
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF133
     SwitchGear 3'UTR luciferase reporter plasmids for ZNF133
     SwitchGear Promoter luciferase reporter plasmids for ZNF133
     Search ThermoFisher Antibodies for ZNF133
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF133
     inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for ZNF133
    Sirion Biotech Customized:
     stable knockdown cell line services for ZNF133
     inducible knockdown cell line services for ZNF133
     design and validation of potent shRNA sequences against ZNF133
     adenovirus for potent knockdown of ZNF133
     adenovirus for overexpression of ZNF133
     stable overexpressing cell line services for ZNF133
     inducible overexpressing cell line services for ZNF133
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZNF133 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4