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ZNF12 Gene

protein-coding   GIFtS: 53
GCID: GC07M006728

Zinc Finger Protein 12

(Previous name: zinc finger protein 325)
(Previous symbol: ZNF325)
  Search for ZNF12
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 121 2     KOX32 3
Zinc Finger Protein 3251 2 3     HZF112
ZNF3251 2 3     Gonadotropin Inducible Transcription Repressor 32
Gonadotropin-Inducible Ovary Transcription Repressor 32 3     Zinc Finger Protein 112
Zinc Finger Protein KOX32 3     GIOT33
GIOT-32 3     

External Ids:    HGNC: 129021   Entrez Gene: 75592   Ensembl: ENSG000001646317   OMIM: 1945365   UniProtKB: P170143   

Export aliases for ZNF12 gene to outside databases

Previous GC identifers: GC07U990124 GC07M006474 GC19M009266 GC07M006503 GC07M006696 GC07M006599


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZNF12 Gene:
This gene is a member of the krueppel C2H2-type zinc-finger protein family and encodes a protein with eight
C2H2-type zinc fingers and a KRAB domain. This nuclear protein is involved in developmental control of gene
expression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
(provided by RefSeq, Jul 2008)

GeneCards Summary for ZNF12 Gene:
ZNF12 (zinc finger protein 12) is a protein-coding gene. An important paralog of this gene is ZNF334.

UniProtKB/Swiss-Prot: ZNF12_HUMAN, P17014
Function: Transcriptional repressor which suppresses activation protein 1 (AP-1)- and serum response element
(SRE)-mediated transcriptional activity




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007819.18  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF12 gene promoter:
         AP-1   GR-beta   SREBP-1c   ATF-2   SREBP-1b   Evi-1   SREBP-1a   GR-alpha   c-Jun   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): ZNF12 promoter sequence
   Search Chromatin IP Primers for ZNF12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.1   Ensembl cytogenetic band:  7p22.1   HGNC cytogenetic band: 7p21.1

ZNF12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF12 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M006728:  view genomic region     (about GC identifiers)

Start:
6,728,064 bp from pter      End:
6,746,566 bp from pter
Size:
18,503 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 6,775,090-6,793,604     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZNF12_HUMAN, P17014 (See protein sequence)
Recommended Name: Zinc finger protein 12  
Size: 697 amino acids; 81202 Da
Developmental stage: Shows a relatively higher expression level in the fetal brain and a lower level in adult. The
expression level in liver is highest at 16 weeks of development and declines from 16 to 24 weeks and is lower in
adult. Expressed strongly in fetal heart on 18 and 24 weeks, but relatively weakly on the other development stage
of embryo, and then reaches a higher level in adult (isoform 3)
Sequence caution: Sequence=BAB14183.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAG57306.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8MYC4 A8WFQ8 B2RNQ7 B4DF45 Q6N016 Q8NHZ0 Q9H9P0 Q9ULZ6
Alternative splicing: 5 isoforms:  P17014-1   P17014-2   P17014-3   P17014-4   P17014-5   

Explore the universe of human proteins at neXtProt for ZNF12: NX_P17014

Explore proteomics data for ZNF12 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys337
  • Modification sites at PhosphoSitePlus

  • See ZNF12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_008887.2  NP_057349.2  

    ENSEMBL proteins: 
     ENSP00000384405   ENSP00000385939   ENSP00000344745   ENSP00000378375  
    Reactome Protein details: P17014

    ZNF12 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    4 InterPro protein domains:
     IPR001909 Krueppel-associated_box
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry P17014

    ProtoNet protein and cluster: P17014

    1 Blocks protein domain: IPB001909 KRAB box

    UniProtKB/Swiss-Prot: ZNF12_HUMAN, P17014
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 15 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    Find genes that share domains with ZNF12           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZNF12_HUMAN, P17014
    Function: Transcriptional repressor which suppresses activation protein 1 (AP-1)- and serum response element
    (SRE)-mediated transcriptional activity

         Genatlas biochemistry entry for ZNF12:
    zinc finger protein 12 (KOX3) (C2H2 type,Kruppel-like)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IBA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZNF12           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for ZNF12:
     Decreased p24 protein expressi  Increased S DNA content  Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZNF12
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    miRNA
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    miRTarBase miRNAs that target ZNF12:
    hsa-mir-181a-5p (MIRT025182)

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    Selected qRT-PCR Assays for microRNAs that regulate ZNF12 (see all 21):
    hsa-miR-520e hsa-miR-302d hsa-miR-125a-5p hsa-miR-302e hsa-miR-520a-3p hsa-miR-372 hsa-miR-125b hsa-miR-155*
    SwitchGear 3'UTR luciferase reporter plasmidZNF12 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZNF12

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZNF12_HUMAN, P17014: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA16806083

    Find genes that share ontologies with ZNF12           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF12 About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with ZNF12           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZNF12
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF12
    Interactions:

        Search GeneGlobe Interaction Network for ZNF12

    1 Interacting protein for ZNF12 (P170143) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ZNF473Q8WTR73I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0045892negative regulation of transcription, DNA-templated IDA16806083

    Find genes that share ontologies with ZNF12           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF12



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZNF12 gene (2 alternative transcripts): 
    NM_006956.2  NM_016265.3  

    Unigene Cluster for ZNF12:

    Zinc finger protein 12
    Hs.431471  [show with all ESTs]
    Unigene Representative Sequence: BC154414
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000404360 ENST00000405858(uc011jxa.1 uc003sqs.1 uc003sqt.1)
    ENST00000342651 ENST00000394917 ENST00000491565
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ZNF12 (see all 21):
    hsa-miR-520e hsa-miR-302d hsa-miR-125a-5p hsa-miR-302e hsa-miR-520a-3p hsa-miR-372 hsa-miR-125b hsa-miR-155*
    SwitchGear 3'UTR luciferase reporter plasmidZNF12 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZNF12
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    GenScript: all cDNA clones in your preferred vector (see all 2): ZNF12 (NM_016265)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF12
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF12
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF12
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZNF12
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF12
      QuantiFast Probe-based Assays in human, mouse, rat ZNF12

    Additional mRNA sequence: 

    AB021643.1 AF505656.1 AK022691.1 AK055709.1 AK293925.1 AY500354.1 BC051892.1 BC137068.1 
    BC137069.1 BC144465.1 BC154414.1 BX640749.1 X52334.1 

    10 DOTS entries:

    DT.95367683  DT.101978958  DT.315766  DT.121038787  DT.100776429  DT.100776428  DT.91693968  DT.95256034 
    DT.91809448  DT.97775124 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF12    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5
    SP1:                                    
    SP2:                                    


    ECgene alternative splicing isoforms for ZNF12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTCCTGTTT
    ZNF12 Expression
    About this image


    ZNF12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 4 entries
             Peripheral blood-derived hematopoietic stem cells (family)
             bone marrow cd34+   
     
     Umbilical Cord (Extraembryonic Tissues)
             stem cells (umbilical cord cd34+)   
     
     Eye (Sensory Organs)
             Retina
    ZNF12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.431471

    UniProtKB/Swiss-Prot: ZNF12_HUMAN, P17014
    Tissue specificity: Widely expressed in various adult tissues and embryonic developmental stages (isoform 3)

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZNF12 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp121 , 5 zinc finger protein 121, 5 77.37(n)1
    81.5(a)1
      5 (82.02 cM)5
    2318661  NM_177681.31  NP_808349.11 
     1432351635 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    32(a)
    1 → many
    2(350396-358052)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    48(a)
    many ↔ many
    GL343676.1(226652-245929)
    zebrafish
    (Danio rerio)
    Actinopterygii CR361547.16
    Uncharacterized protein
    40(a)
    many ↔ many
    4(32922401-32928051) ENSDARG00000094141


    ENSEMBL Gene Tree for ZNF12 (if available)
    TreeFam Gene Tree for ZNF12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF12 gene
    ZNF3342  ZNF4202  ZNF780A2  ZNF6652  ZNF72  ZNF232  ZNF33A2  RBAK2  
    ZNF7172  ZNF302  ZNF5732  ZNF33B2  ZNF5402  ZNF2512  ZNF6052  ZNF842  
    ZNF1892  ZNF5712  ZNF6302  ZNF3372  ZNF2832  ZNF4042  ZNF1352  ZNF4842  
    ZNF3452  ZNF1842  ZNF6992  ZNF412  ZNF6152  ZNF4702  ZNF5692  
    Selected SIMAP similar genes for ZNF12 using alignment to 2 protein entries:     ZNF12_HUMAN (see all proteins) (see all similar genes):
    HZF11    PMS2P3    POM121C    FIK    ZFP90    ZNF78L1
    ZNF793    ZNF300P1    ZNF720    ZNF573    ZNF790    ZNF569
    ZNF84    ZNF415    ZNF616    ZNF780A    ZFP41    ZNF323

    Find genes that share paralogs with ZNF12           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for ZNF12
    PGOHUM00000257788 PGOHUM00000242214


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF12 (see all 490)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs733312261,2
    C,F--6727586(+) GTATAG/CGGAAA 2 -- ds50012Minor allele frequency- C:0.05WA 120
    rs1476672001,2
    --6727646(+) TTTCCC/TGCAAA 2 -- ds50010--------
    rs1165302391,2
    F--6727705(+) TTTCCG/ATGGCA 2 -- ds50011Minor allele frequency- A:0.09WA 118
    rs733312281,2
    C,F--6727707(+) TCCGTG/CGCACC 2 -- ds50012Minor allele frequency- C:0.07WA 120
    rs789922091,2
    C,F--6727744(+) CAGCCC/TATGCT 2 -- ds50011Minor allele frequency- T:0.09WA 118
    rs778256821,2
    C,F--6727814(+) TTTTTG/TATGTA 2 -- ds50011Minor allele frequency- T:0.09WA 118
    rs1155818521,2
    C,F--6727833(+) TGTGAT/CAGGAA 2 -- ds50011Minor allele frequency- C:0.09WA 118
    rs1865632511,2
    --6728007(+) TATACA/GTACCA 2 -- ds50010--------
    rs284984201,2
    C,F--6728011(+) CGTACC/AAGACC 2 -- ds50012Minor allele frequency- A:0.06WA NA 238
    rs1424786651,2
    --6728096(+) AATGCA/GTATTG 2 -- ut310--------

    HapMap Linkage Disequilibrium report for ZNF12 (6728064 - 6746566 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ZNF12 (see all 15):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2669093CNV Deletion23128226
    esv2733934CNV Deletion23290073
    esv4389CNV Deletion18987735
    esv2560724CNV Deletion19546169
    dgv1120e201CNV Deletion23290073
    nsv436904CNV Insertion17901297
    dgv7151n71CNV Loss21882294
    esv32852CNV Loss17666407
    esv7643CNV Loss19470904
    nsv887439CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 194536    OMIM disorders: --


    Find genes that share disorders with ZNF12           About GenesLikeMe

    Genetic Association Database (GAD): ZNF12
    Human Genome Epidemiology (HuGE) Navigator: ZNF12 (1 document)

    Export disorders for ZNF12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF12 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with ZNF12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ZNF325, a novel human zinc finger protein with a RBaK-like RB-binding domain, inhibits AP-1- and SRE-mediated transcriptional activity. (PubMed id 16806083)1, 2 Zhao Y.... Li Y. (Biochem. Biophys. Res. Commun. 2006)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Multiple genes encoding zinc finger domains are expressed in human T cells. (PubMed id 2288909)1, 2 Thiesen H.-J. (New Biol. 1990)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    6. Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection. (PubMed id 21083371)4 Chinn L.W....O'Brien S.J. (J. Infect. Dis. 2010)
    7. Identification of host proteins required for HIV infection through a functional genomic screen. (PubMed id 18187620)1 Brass A.L....Elledge S.J. (Science 2008)
    8. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PubMed id 17903296)4 Kiel D.P....Karasik D. (BMC Med. Genet. 2007)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7559 HGNC: 12902 Ensembl:ENSG00000164631 euGenes: HUgn7559 ECgene: ZNF12
    H-InvDB: ZNF12

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZNF12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZNF12 gene:
    Search GeneIP for patents involving ZNF12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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