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Aliases for ZNF114 Gene

Aliases for ZNF114 Gene

  • Zinc Finger Protein 114 2 3

External Ids for ZNF114 Gene

Previous GeneCards Identifiers for ZNF114 Gene

  • GC19U990132
  • GC19P053467
  • GC19P048775
  • GC19P045156
  • GC19P048675

Summaries for ZNF114 Gene

GeneCards Summary for ZNF114 Gene

ZNF114 (Zinc Finger Protein 114) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression.

UniProtKB/Swiss-Prot for ZNF114 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF114 Gene

Genomics for ZNF114 Gene

Regulatory Elements for ZNF114 Gene

Genomic Location for ZNF114 Gene

Start:
48,172,318 bp from pter
End:
48,287,608 bp from pter
Size:
115,291 bases
Orientation:
Plus strand

Genomic View for ZNF114 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF114 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF114 Gene

Proteins for ZNF114 Gene

  • Protein details for ZNF114 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NC26-ZN114_HUMAN
    Recommended name:
    Zinc finger protein 114
    Protein Accession:
    Q8NC26
    Secondary Accessions:
    • A8K6B0
    • Q08AQ6

    Protein attributes for ZNF114 Gene

    Size:
    417 amino acids
    Molecular mass:
    47747 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF114 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF114 Gene

Proteomics data for ZNF114 Gene at MOPED

Post-translational modifications for ZNF114 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF114 Gene

No data available for DME Specific Peptides for ZNF114 Gene

Domains for ZNF114 Gene

Gene Families for ZNF114 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF114 Gene

Suggested Antigen Peptide Sequences for ZNF114 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NC26

UniProtKB/Swiss-Prot:

ZN114_HUMAN :
  • Q8NC26
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF114: view

Function for ZNF114 Gene

Molecular function for ZNF114 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF114 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF114: view

miRNA for ZNF114 Gene

miRTarBase miRNAs that target ZNF114

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF114 Gene

Localization for ZNF114 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF114 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF114 Gene COMPARTMENTS Subcellular localization image for ZNF114 gene
Compartment Confidence
nucleus 4
cytosol 1

Gene Ontology (GO) - Cellular Components for ZNF114 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with ZNF114: view

Pathways for ZNF114 Gene

SuperPathways for ZNF114 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF114: view

Pathways by source for ZNF114 Gene

2 Reactome pathways for ZNF114 Gene

Gene Ontology (GO) - Biological Process for ZNF114 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZNF114: view

Transcripts for ZNF114 Gene

Unigene Clusters for ZNF114 Gene

Zinc finger protein 114:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF114 Gene

No ASD Table

Relevant External Links for ZNF114 Gene

GeneLoc Exon Structure for
ZNF114
ECgene alternative splicing isoforms for
ZNF114

Expression for ZNF114 Gene

mRNA expression in normal human tissues for ZNF114 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF114 Gene

This gene is overexpressed in Thyroid (6.9).

SOURCE GeneReport for Unigene cluster for ZNF114 Gene Hs.511883

genes like me logo Genes that share expressions with ZNF114: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF114 Gene

Orthologs for ZNF114 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF114 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF114 35
  • 98.63 (n)
  • 98.07 (a)
ZNF114 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF114 35
  • 69.02 (n)
  • 52.44 (a)
ZNF114 36
  • 52 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF114 35
  • 72.06 (n)
  • 54.9 (a)
ZNF114 36
  • 50 (a)
OneToOne
Species with no ortholog for ZNF114:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF114 Gene

ENSEMBL:
Gene Tree for ZNF114 (if available)
TreeFam:
Gene Tree for ZNF114 (if available)

Paralogs for ZNF114 Gene

Selected SIMAP similar genes for ZNF114 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF114: view

No data available for Paralogs for ZNF114 Gene

Variants for ZNF114 Gene

Sequence variations from dbSNP and Humsavar for ZNF114 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs373185 -- 48,269,483(-) ccagc(C/T)tgggt upstream-variant-2KB
rs397831 -- 48,287,570(-) CCTCC(C/T)TTCAG utr-variant-3-prime
rs439847 -- 48,274,508(+) TATAT(A/G/T)TTTTT intron-variant
rs524993 -- 48,287,723(+) CATCT(C/T)TACAA intron-variant, downstream-variant-500B
rs1504519 -- 48,280,045(-) CCCAC(G/T)GGCAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF114 Gene

Variant ID Type Subtype PubMed ID
nsv9739 CNV Gain+Loss 18304495
esv34181 CNV Loss 18971310
nsv469623 CNV Complex 16826518
nsv833854 CNV Loss 17160897
esv2657727 CNV Deletion 23128226
esv2672581 CNV Deletion 23128226
esv269836 CNV Insertion 20981092

Relevant External Links for ZNF114 Gene

HapMap Linkage Disequilibrium report
ZNF114

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF114 Gene

Disorders for ZNF114 Gene

No disorders were found for ZNF114 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF114 Gene

Publications for ZNF114 Gene

  1. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PMID: 8467795) Bellefroid E.J. … Martial J.A. (EMBO J. 1993) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PMID: 19056867) Gonzales P.A. … Knepper M.A. (J. Am. Soc. Nephrol. 2009) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for ZNF114 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF114
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF114
  • Block miRNA regulation of ZNF114 using miScript Target Protectors

Sources for ZNF114 Gene

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