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Aliases for ZNF112 Gene

Aliases for ZNF112 Gene

  • Zinc Finger Protein 112 2 3 5
  • Zinc Finger Protein 228 2 3 4
  • Zfp-112 3 4
  • ZNF228 3 4
  • ZFP112 3 4
  • Zinc Finger Protein 112 Homolog (Mouse) 2
  • Zinc Finger Protein 112 Homolog 3
  • Zinc Finger Protein 112 (Y14) 3

External Ids for ZNF112 Gene

Previous HGNC Symbols for ZNF112 Gene

  • ZFP112
  • ZNF228

Previous GeneCards Identifiers for ZNF112 Gene

  • GC19U990130
  • GC00U934196
  • GC19M044832

Summaries for ZNF112 Gene

GeneCards Summary for ZNF112 Gene

ZNF112 (Zinc Finger Protein 112) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF229.

UniProtKB/Swiss-Prot for ZNF112 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF112 Gene

Genomics for ZNF112 Gene

Regulatory Elements for ZNF112 Gene

Enhancers for ZNF112 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF112 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF112 Gene

44,326,553 bp from pter
44,367,217 bp from pter
40,665 bases
Minus strand

Genomic View for ZNF112 Gene

Genes around ZNF112 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF112 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF112 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF112 Gene

Proteins for ZNF112 Gene

  • Protein details for ZNF112 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 112
    Protein Accession:
    Secondary Accessions:
    • A4FU53
    • Q9HCA7

    Protein attributes for ZNF112 Gene

    913 amino acids
    Molecular mass:
    105842 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF112 Gene


neXtProt entry for ZNF112 Gene

Proteomics data for ZNF112 Gene at MOPED

Post-translational modifications for ZNF112 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF112 Gene

No data available for DME Specific Peptides for ZNF112 Gene

Domains & Families for ZNF112 Gene

Gene Families for ZNF112 Gene

Protein Domains for ZNF112 Gene

Suggested Antigen Peptide Sequences for ZNF112 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 17 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 17 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF112: view

Function for ZNF112 Gene

Molecular function for ZNF112 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF112: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF112 Gene

Localization for ZNF112 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF112 Gene

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZNF112 Gene

Pathways & Interactions for ZNF112 Gene

SuperPathways for ZNF112 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF112: view

Pathways by source for ZNF112 Gene

2 Reactome pathways for ZNF112 Gene

Interacting Proteins for ZNF112 Gene

Gene Ontology (GO) - Biological Process for ZNF112 Gene


No data available for SIGNOR curated interactions for ZNF112 Gene

Drugs & Compounds for ZNF112 Gene

No Compound Related Data Available

Transcripts for ZNF112 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF112 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d
SP3: -
SP4: - -

Relevant External Links for ZNF112 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF112 Gene

mRNA expression in normal human tissues for ZNF112 Gene

Protein differential expression in normal tissues from HIPED for ZNF112 Gene

This gene is overexpressed in Testis (46.6) and CD8 Tcells (22.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF112 Gene

genes like me logo Genes that share expression patterns with ZNF112: view

Protein tissue co-expression partners for ZNF112 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF112 Gene

Orthologs for ZNF112 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF112 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZFP112 35
  • 85.63 (n)
  • 80.62 (a)
ZNF112 36
  • 80 (a)
(Canis familiaris)
Mammalia ZFP112 35
  • 89.43 (n)
  • 87.9 (a)
(Mus musculus)
Mammalia Zfp112 35
  • 75.17 (n)
  • 65.63 (a)
Zfp112 16
Zfp112 36
  • 65 (a)
(Pan troglodytes)
Mammalia ZFP112 35
  • 98.97 (n)
  • 98.46 (a)
ZNF112 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Zfp112 35
  • 73.87 (n)
  • 64.48 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 47 (a)
(Gallus gallus)
Aves -- 36
  • 47 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 52 (a)
(Danio rerio)
Actinopterygii si:ch73-367f21.5 36
  • 41 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5245 36
  • 35 (a)
(Caenorhabditis elegans)
Secernentea C27A12.2 36
  • 19 (a)
tag-146 36
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9363 36
  • 27 (a)
Species with no ortholog for ZNF112:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF112 Gene

Gene Tree for ZNF112 (if available)
Gene Tree for ZNF112 (if available)

Paralogs for ZNF112 Gene

(547) SIMAP similar genes for ZNF112 Gene using alignment to 6 proteins: Pseudogenes for ZNF112 Gene

genes like me logo Genes that share paralogs with ZNF112: view

Variants for ZNF112 Gene

Sequence variations from dbSNP and Humsavar for ZNF112 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs4280359 - 44,329,698(+) TGAGT(C/G)AATAT reference, missense
rs16978965 - 44,329,687(+) CATTC(C/T)CTATA reference, missense
rs10419604 - 44,329,315(+) TGTAT(G/T)TATAG reference, missense
rs2609881 - 44,327,836(-) ATGTG(A/C)GGTGT reference, missense
rs11673395 - 44,336,701(+) GTCTG(A/G)CTTGA reference, missense

Variation tolerance for ZNF112 Gene

Residual Variation Intolerance Score: 69.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.83; 83.53% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for ZNF112 Gene

Disorders for ZNF112 Gene

Relevant External Links for ZNF112

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF112 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF112 Gene

Publications for ZNF112 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PMID: 12743021) Shannon M. … Stubbs L. (Genome Res. 2003) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF112 Gene

Sources for ZNF112 Gene