ZNF107 Gene
protein-coding GIFtS: 44
GCID: GC07P064126
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zinc finger protein 107(Previous names: zinc finger protein 588, zinc finger protein 107 (Y8) ) (Previous symbol: ZNF588)
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Aliases for ZNF107 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 1071 2 | | Zinc Finger Protein ZFD252 3 | | Zinc Finger Protein 5881 2 3 | | Zinc Finger Protein 107 (Y8)1 | | ZFD251 2 3 | | Y82 | | ZNF5881 2 3 | | C2H2 Type Zinc-Finger Protein2 | | Smap-71 | | Zinc Finger Protein (ZFD25)2 |
Export aliases for ZNF107 gene to outside databasesPrevious GC identifers: GC07U990127 GC07P063764 GC07P060507 |
Summaries for ZNF107 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ZNF107: Zinc finger proteins (ZNFs), which bind nucleic acids, perform many key functions, the most important of which isregulating transcription. See ZNF91 (MIM 603971) for general information on ZNFs.(supplied by OMIM, Mar 2008) UniProtKB/Swiss-Prot: ZN107_HUMAN, Q9UII5Function: May be involved in transcriptional regulation
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Genomic Views for ZNF107 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079593.2
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ZNF107 gene promoter: p53 NRSF form 2 Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF107
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF107 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q11.2 Ensembl cytogenetic band: 7q11.21 HGNC cytogenetic band: 7q11.2ZNF107 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P064126: view genomic region
(about GC identifiers)
Start:
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64,126,511 bp from pter |
End:
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64,171,404 bp from pter |
Size:
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44,894 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 63,464,105-63,508,998 |
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Proteins for ZNF107 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ZN107_HUMAN, Q9UII5 (See
protein sequence)Recommended Name: Zinc finger protein 107 Size: 783 amino acids; 90673 Da
Subcellular location: Nucleus (Potential)Explore the universe of human proteins at neXtProt for ZNF107: NX_Q9UII5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UII5 ZNF107 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (2 alternative transcripts):
NP_001013768.1 NP_057304.1 ENSEMBL proteins: ENSP00000353234 ENSP00000343443 ENSP00000378789 ENSP00000400037 Human Recombinant Protein Products for ZNF107:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF107 for ontologies About GeneDecksing
ZNF107 Antibody Products: Assay Products for ZNF107: |
Protein
Domains / Families for ZNF107 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF107 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UII5ProtoNet protein and cluster: Q9UII5 UniProtKB/Swiss-Prot: ZN107_HUMAN, Q9UII5Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 25 C2H2-type zinc fingers |
Function for ZNF107 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: ZN107_HUMAN, Q9UII5Function: May be involved in transcriptional regulation Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF107 for ontologies About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF107 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF107 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF107 (NM_016220) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF107 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF107  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF107 |
|
Pathways & Interactions for ZNF107 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF107
2 Interacting proteins for ZNF107 (Q9UII52, 3) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0008150 | biological_process |
ND | -- |
ZNF107 for ontologies About GeneDecksing
|
Drugs & Compounds for ZNF107 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ZNF107 Search CenterWatch for drugs/clinical trials and news about ZNF107 / ZN107 
|
Transcripts for ZNF107 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ZNF107 gene (2 alternative transcripts): NM_001013746.1 NM_016220.3 Unigene Cluster for ZNF107: Zinc finger protein 107 Hs.732661 [show with all ESTs]Unigene Representative Sequence: NM_0162204 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000360117 ENST00000344930(uc003tte.3) ENST00000395391 ENST00000423627(uc003ttd.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF107 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF107 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF107 (NM_016220) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF107 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF107  |
Additional cDNA sequence: AB014735.1 AK303931.1 BC017809.1 BC047243.1 8 DOTS entries: DT.95144794 DT.102833779 DT.121053218 DT.121053248 DT.411593 DT.208744 DT.411536 DT.91932667 24/66 AceView cDNA sequences (see all 66): AA827146 BC017809 AA747556 AI884422 CF136291 NM_016220 AB014735 BU193507 BF796377 BX476718 BG502892 AL601710 AA287275 BG503326 AI760251 AI394116 AA278839 AA279103 BQ228688 BG503639 AA599639 BG615050 AA732792 BC053669 GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF107 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | |
| SP1: | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |
| SP4: | |   | - |   | - |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ZNF107
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Expression for ZNF107 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF107 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AAGTAGGTTT
 About this image See ZNF107 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ZNF107
SOURCE GeneReport for Unigene cluster: Hs.732661
UniProtKB/Swiss-Prot: ZN107_HUMAN, Q9UII5Tissue specificity: Expressed in brain, heart, skeletal muscle, kidney and pancreas. Weakly expressed in aorta, liverand lung SABiosciences Custom PCR Arrays for ZNF107
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF107 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF107 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF107 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF107 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF107 |
Orthologs for ZNF107 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF107 gene from 3/14 species (see all 14) About this table
ENSEMBL Gene Tree for ZNF107 (if available) TreeFam Gene Tree for ZNF107 (if available)  |
Paralogs for ZNF107 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ZNF107 gene
- ZNF852 ZNF4932 ZNF4862 ZNF1002 ZNF922 ZNF7322 ZNF1382 ZNF6752
- ZNF5062 ZNF2732 ZNF66P2 ZNF6952 ZNF6262 ZNF6802 ZNF2532 ZNF4792
- ZNF932 ZNF4922 ZNF6822 ZNF6762 ZNF1412 ZNF6812 ZNF6792 ZNF2572
- ZNF2542 ZNF7372 ZNF724P2 ZNF982 ZNF849P2 ZNF7162 ZNF7142 ZNF4292
- ZNF4302 ZNF7302 ZNF6782 ZNF7082 ZNF1172 ZNF4312 ZNF902
18/393 SIMAP similar genes for ZNF107 using alignment to 3 protein entries: ZN107_HUMAN (see all proteins)
(see all similar genes):smap-7 ZNF232 ZFS-1 ZNF431 ZNF675 ZNF85 ZNF117 ZNF714 DKFZp762K012 ZNF273 ZNF420 ZNF429 ZNF676 ZNF708 ZSCAN21 ZNF138 ZNF430 ZNF492
ZNF107 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ZNF107 PGOHUM00000234558
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Genomic Variants for ZNF107 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 7 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF107 (64126511 - 64171404 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for ZNF107 2 CNVs: 69927 5239  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF107 |
|
Disorders
/ Diseases for ZNF107 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF107 for disorders About MalaCards
ZNF107 for disorders About GeneDecksing
OMIM gene information: 603989
OMIM disorders: --
Export disorders for ZNF107 gene to outside databases
|
Publications for ZNF107 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF107 gene integrated from 9 sources: (articles sorted by number of sources associating them with ZNF107) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Cloning and characterization of a novel gene encoding a zinc finger protein with 25 fingers. (PubMed id 10673043)1, 2 Li X.-A.... Yutani C. (1999)
- Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PubMed id 8467795)1, 3 Bellefroid E.J.... Martial J.A. (1993)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A universal strategy for proteomic studies of SUMO an d other ubiquitin-like modifiers. (PubMed id 15576338)1 Rosas-Acosta G....Wilson V.G. (2005)
- Functional proteomics mapping of a human signaling pathway. (PubMed id 15231748)1 Colland F....Gauthier J.M. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1 Hillier L.W.... Wilson R.K. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF107 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ZNF107 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF107 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF107 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ZNF107 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF107 gene: Search GeneIP for patents involving ZNF107
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ZNF107 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
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 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF107 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF107 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF107 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ZNF107 | | OriGene 3'-UTR Clone for ZNF107 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF107 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF107 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ZNF107 | | OriGene Custom Protein Services for ZNF107 | | OriGene Custom Immunoassay Development | | |
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| | | Search Tocris compounds for ZNF107 |
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 | | ZNF107 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF107 |
|  |  |  |  | | | ThermoFisher Antibody for ZNF107 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF107 |
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