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Aliases for ZNF106 Gene

Aliases for ZNF106 Gene

  • Zinc Finger Protein 106 2 3
  • SH3-Domain Binding Protein 3 2 3
  • Zinc Finger Protein 474 3 4
  • ZFP106 3 4
  • SH3BP3 3 4
  • ZNF474 3 4
  • Zinc Finger Protein 106 Homolog (Mouse) 2
  • Zfp-106 4

External Ids for ZNF106 Gene

Previous HGNC Symbols for ZNF106 Gene

  • ZFP106

Previous GeneCards Identifiers for ZNF106 Gene

  • GC19U990126
  • GC15M042707

Summaries for ZNF106 Gene

GeneCards Summary for ZNF106 Gene

ZNF106 (Zinc Finger Protein 106) is a Protein Coding gene. GO annotations related to this gene include SH3 domain binding and opioid peptide activity. An important paralog of this gene is WDR86.

Gene Wiki entry for ZNF106 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF106 Gene

Genomics for ZNF106 Gene

Genomic Location for ZNF106 Gene

Start:
42,412,437 bp from pter
End:
42,491,197 bp from pter
Size:
78,761 bases
Orientation:
Minus strand

Genomic View for ZNF106 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF106 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF106 Gene

No data available for Regulatory Elements for ZNF106 Gene

Proteins for ZNF106 Gene

  • Protein details for ZNF106 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H2Y7-ZN106_HUMAN
    Recommended name:
    Zinc finger protein 106
    Protein Accession:
    Q9H2Y7
    Secondary Accessions:
    • B4DZ40
    • E9PE29
    • Q6NSD9
    • Q6PEK1
    • Q86T43
    • Q86T45
    • Q86T50
    • Q86T58
    • Q86TA9
    • Q96M37
    • Q9H7B8

    Protein attributes for ZNF106 Gene

    Size:
    1883 amino acids
    Molecular mass:
    208883 Da
    Quaternary structure:
    • Interacts with KNOP1.
    SequenceCaution:
    • Sequence=AAH58023.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAH70244.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAB14976.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAD91134.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF106 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF106 Gene

Proteomics data for ZNF106 Gene at MOPED

Post-translational modifications for ZNF106 Gene

  • Ubiquitination at Lys243, Lys356, Lys539, and Lys775
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZNF106 Gene

Domains for ZNF106 Gene

Gene Families for ZNF106 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Graphical View of Domain Structure for InterPro Entry

Q9H2Y7

UniProtKB/Swiss-Prot:

ZN106_HUMAN :
  • Q9H2Y7
Similarity:
  • Contains 2 C2H2-type zinc fingers.
  • Contains 6 WD repeats.
genes like me logo Genes that share domains with ZNF106: view

No data available for Suggested Antigen Peptide Sequences for ZNF106 Gene

Function for ZNF106 Gene

Gene Ontology (GO) - Molecular Function for ZNF106 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001515 opioid peptide activity IEA --
GO:0005515 protein binding --
GO:0017124 SH3 domain binding IEA --
GO:0044822 poly(A) RNA binding IDA 22658674
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF106: view

Phenotypes for ZNF106 Gene

genes like me logo Genes that share phenotypes with ZNF106: view

Animal Model Products

CRISPR Products

miRNA for ZNF106 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF106

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF106 Gene

Localization for ZNF106 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF106 Gene

Nucleus, nucleolus.

Gene Ontology (GO) - Cellular Components for ZNF106 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005730 nucleolus IEA --
GO:0005829 cytosol IEA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with ZNF106: view

No data available for Subcellular locations from COMPARTMENTS for ZNF106 Gene

Pathways for ZNF106 Gene

SuperPathways for ZNF106 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF106 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008286 insulin receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with ZNF106: view

No data available for Pathways by source for ZNF106 Gene

Transcripts for ZNF106 Gene

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF106

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF106
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF106 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18a ·
SP1: -
SP2: -
SP3:
SP4: -
SP5:
SP6:
SP7:
SP8: -
SP9:
SP10: -
SP11:
SP12: - - -
SP13: - - - - -
SP14:

ExUns: 18b ^ 19 ^ 20a · 20b ^ 21a · 21b · 21c ^ 22a · 22b ^ 23 ^ 24a · 24b ^ 25
SP1: - -
SP2: - -
SP3: - -
SP4: - - -
SP5:
SP6:
SP7:
SP8:
SP9: - -
SP10:
SP11: -
SP12:
SP13:
SP14:

Relevant External Links for ZNF106 Gene

GeneLoc Exon Structure for
ZNF106
ECgene alternative splicing isoforms for
ZNF106

Expression for ZNF106 Gene

mRNA expression in normal human tissues for ZNF106 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF106 Gene

This gene is overexpressed in Muscle - Skeletal (12.3) and Heart - Left Ventricle (6.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF106 Gene

genes like me logo Genes that share expressions with ZNF106: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF106 Gene

Orthologs for ZNF106 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF106 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZFP106 35
  • 99.75 (n)
  • 99.91 (a)
ZNF106 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF106 35
  • 89.84 (n)
  • 88.25 (a)
ZNF106 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF106 35
  • 89.81 (n)
  • 89.45 (a)
ZNF106 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp106 35
  • 82.67 (n)
  • 78.28 (a)
Zfp106 16
Zfp106 36
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF106 36
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC688018 35
  • 81.93 (n)
  • 78.19 (a)
chicken
(Gallus gallus)
Aves ZFP106 35
  • 66.87 (n)
  • 62.68 (a)
ZNF106 36
  • 59 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF106 36
  • 56 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.9777 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.16042 35
znf106 35
  • 59.08 (n)
  • 53.57 (a)
zebrafish
(Danio rerio)
Actinopterygii znf106a 36
  • 40 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG14322 36
  • 18 (a)
OneToMany
Species with no ortholog for ZNF106:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF106 Gene

ENSEMBL:
Gene Tree for ZNF106 (if available)
TreeFam:
Gene Tree for ZNF106 (if available)

Paralogs for ZNF106 Gene

Paralogs for ZNF106 Gene

Selected SIMAP similar genes for ZNF106 Gene using alignment to 8 proteins:

Pseudogenes.org Pseudogenes for ZNF106 Gene

genes like me logo Genes that share paralogs with ZNF106: view

Variants for ZNF106 Gene

Sequence variations from dbSNP and Humsavar for ZNF106 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs934876 -- 42,461,319(-) TCCCC(C/T)GTGAT intron-variant
rs934877 -- 42,421,588(-) GTGGC(A/G)TGGTT intron-variant
rs1062015 -- 42,416,317(-) CAGCA(A/C)CTAAG utr-variant-3-prime
rs1062016 -- 42,416,028(-) GTGGC(C/T)GGGCG utr-variant-3-prime
rs1062038 -- 42,415,645(-) GCAGA(C/G)CATCC utr-variant-3-prime

Relevant External Links for ZNF106 Gene

HapMap Linkage Disequilibrium report
ZNF106

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF106 Gene

Disorders for ZNF106 Gene

No disorders were found for ZNF106 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF106 Gene

Publications for ZNF106 Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  2. Dual promoter structure of ZFP106: regulation by myogenin and nuclear respiratory factor-1. (PMID: 15656981) Grasberger H. … Bell G.I. (Gene 2005) 3 23
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Nucleolar proteome dynamics. (PMID: 15635413) Andersen J.S. … Mann M. (Nature 2005) 3

Products for ZNF106 Gene

Sources for ZNF106 Gene

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