ZNF101 Gene
protein-coding GIFtS: 49
GCID: GC19P019779
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zinc finger protein 101(Previous name: zinc finger protein 101 (Y2) )
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Aliases
for ZNF101 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 1011 2 | | HZF121 2 | | Zinc Finger Protein 101 (Y2)1 2 | | Zinc Finger Protein HZF122 3 | | DKFZp570I01641 | | Zinc Finger Protein 122 |
Export aliases for ZNF101 gene to outside databasesPrevious GC identifers: GC19U990121 GC19P019640 GC19P019341 |
Summaries
for ZNF101 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZNF101:
Zinc finger proteins (ZNFs), such as ZNF101, bind nucleic acids and perform many key functions, the most important ofwhich is regulating transcription (summary by Bellefroid et al., 1993 (PubMed 8467795)). See ZNF91 (MIM 603971) forgeneral information on ZNFs.(supplied by OMIM, Nov 2010)
UniProtKB/Swiss-Prot: ZN101_HUMAN, Q8IZC7Function: May be involved in transcriptional regulation
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Genomic Views
for ZNF101 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF101 gene promoter:
AhR AML1a HTF CUTL1 Arnt Roaz POU2F1 POU2F1a TGIF Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF101
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF101 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.11 Ensembl cytogenetic band: 19p13.11 HGNC cytogenetic band: 19p13.11ZNF101 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P019779: view genomic region
(about GC identifiers)
Start:
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19,779,605 bp from pter |
End:
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19,794,318 bp from pter |
Size:
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14,714 bases |
Orientation:
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plus strand |
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Proteins
for ZNF101 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN101_HUMAN, Q8IZC7 (See
protein sequence)Recommended Name: Zinc finger protein 101 Size: 436 amino acids; 50339 Da
Subcellular location: Nucleus (Probable)Explore the universe of human proteins at neXtProt for ZNF101: NX_Q8IZC7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IZC7
ZNF101 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_149981.2
ENSEMBL proteins: ENSP00000467112 ENSP00000319716 ENSP00000466697 ENSP00000468049 ENSP00000400952 ENSP00000466744 Reactome Protein details: Q8IZC7
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF101 for ontologies About GeneDecksing
ZNF101 Antibody Products:
Assay Products for ZNF101: |
Protein
Domains /
Families
for ZNF101 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF101 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IZC7ProtoNet protein and cluster: Q8IZC7 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN101_HUMAN, Q8IZC7Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 10 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF101 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN101_HUMAN, Q8IZC7Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF101
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF101
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for ZNF101 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF101 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF101 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF101 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF101 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF101
ZNF101 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF101
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5/6 Interacting proteins for ZNF101 (Q8IZC72, 3 ENSP000003197164) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF101 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF101 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF101
Search CenterWatch for drugs/clinical trials and news about ZNF101 / ZN101
|
Transcripts
for ZNF101 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF101 gene: NM_033204.2 Unigene Cluster for ZNF101: Zinc finger protein 101 Hs.631642 [show with all ESTs]Unigene Representative Sequence: AK0971698 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000541458 ENST00000318110 ENST00000444249 ENST00000592502 ENST00000415784(uc010ecg.2)
ENST00000415440(uc002nni.2 uc002nnj.2) ENST00000585565 ENST00000586745
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF101
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF101
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF101 (NM_033204) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF101 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF101 |
Additional cDNA sequence: AK097169.1 AY149174.1 BC011502.1 BC094808.1 BC119680.1 BC119681.1 5 DOTS entries: DT.75163712 DT.95368838 DT.121492603 DT.121493179 DT.121425048 24/38 AceView cDNA sequences (see all 38): BP344642 AA232904 AL096747 AK097169 BQ685360 BC011502 BM797078 BF974514 CB148564 AK123904 BU532885 BF794147 BI837762 BE314293 AA380298 BE464819 BI838075 CB069539 AI434146 NM_033204 AY149174 BX105661 W86428 BE313621
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF101 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b |
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| SP1: | | | | | | | | | |
| SP2: | | | | | | | | |
ECgene alternative splicing isoforms for ZNF101
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Expression
for ZNF101 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF101 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZNF101 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF101
SOURCE GeneReport for Unigene cluster: Hs.631642
UniProtKB/Swiss-Prot: ZN101_HUMAN, Q8IZC7Tissue specificity: Expressed in a variety of adult and fetal tissues
SABiosciences Custom PCR Arrays for ZNF101
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF101
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF101 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF101 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF101 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF101 |
Orthologs
for ZNF101 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF101 (if available)
TreeFam Gene Tree for ZNF101 (if available) |
Paralogs
for ZNF101 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF101 gene
- ZNF6692 ZNF4902 ZNF5642 ZNF4412 ZNF8782 ENSG000002671792 ZNF142 ENSG000001968262
- ZNF7002 ZNF692 ZNF4402 ZNF4432 ZNF442 ZNF4392 ZNF8232 ZNF4912
- ENSG000001884742 ZNF5552 ZNF7092 ZNF6252 ZNF7992 ZNF202 ZNF7912 ZNF4422
- ZNF4332 ZNF572 ZNF5632 ZNF6272 ENSG000002573552 ZNF1362 ZNF5562 ZNF6702
- ZNF7632 ZNF1242 ZNF6992 ZNF8442 ZNF772
18/523 SIMAP similar genes for ZNF101 using alignment to 6 protein entries: ZN101_HUMAN (see all proteins)
(see all similar genes):DKFZp570I0164 AVGR4 MRPS17 ZNF226 ZNF738 ZFP90
KRBOX1 ZFP57 ZNF175 AVGR5 KRBOX4 ZNF235
ZNF596 MGC12518 PMS2P3 POM121C ZNF527 ZNF624
ZNF101 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ZNF101
PGOHUM00000238382 PGOHUM00000244381
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Genomic Variants
for ZNF101 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF101 (19779605 - 19794318 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF101: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF101 |
|
Disorders
/ Diseases
for ZNF101 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF101 for disorders About GeneDecksing
OMIM gene information: 603983
OMIM disorders: --
1  disease for ZNF101: About MalaCardscoronary heart disease
Export disorders for ZNF101 gene to outside databases
|
Publications
for ZNF101 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF101 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF101) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel Kruppel-associated box identified in a panel of mammalian zinc finger proteins. (PubMed id 14727140)1, 2 Looman C.... Abrink M. (2004)
- Human chromosome 19 and related regions in mouse: con servative and lineage-specific evolution. (PubMed id 11441184)1, 3 Dehal P....Stubbs L. (2001)
- Genome-wide association study identifies novel loci as sociated with circulating phospho- and sphingolipid concentrations. (PubMed id 22359512)1 Demirkan A....Schmitz G. (2012)
- Genetic variants influencing circulating lipid levels and risk of coronary artery disease. (PubMed id 20864672)1 Waterworth D.M....Sandhu M.S. (2010)
- Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (PubMed id 19060911)1 Aulchenko Y.S....Peltonen L. (2009)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PubMed id 8467795)1 Bellefroid E.J.... Martial J.A. (1993)
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External Searches for ZNF101 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF101 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF101 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF101 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF101 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF101 gene:
Search GeneIP for patents involving ZNF101
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF101 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF101 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF101 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF101 | | | OriGene Protein Over-expression Lysate for ZNF101 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF101 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF101 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF101 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF101 | | OriGene Custom Protein Services for ZNF101 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF101 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF101 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF101 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF101 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF101 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF101 |
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 | | | ZNF101 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF101 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF101 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF101 |
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