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Aliases for ZNF101 Gene

Aliases for ZNF101 Gene

  • Zinc Finger Protein 101 2 3
  • Zinc Finger Protein 101 (Y2) 2 3
  • Zinc Finger Protein HZF12 3 4
  • Zinc Finger Protein 12 3
  • HZF12 3

External Ids for ZNF101 Gene

Summaries for ZNF101 Gene

Entrez Gene Summary for ZNF101 Gene

  • Zinc finger proteins (ZNFs), such as ZNF101, bind nucleic acids and perform many key functions, the most important of which is regulating transcription (summary by Bellefroid et al., 1993 [PubMed 8467795]). See ZNF91 (MIM 603971) for general information on ZNFs.[supplied by OMIM, Nov 2010]

GeneCards Summary for ZNF101 Gene

ZNF101 (Zinc Finger Protein 101) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF709.

UniProtKB/Swiss-Prot for ZNF101 Gene

  • May be involved in transcriptional regulation

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF101 Gene

Genomics for ZNF101 Gene

Genomic Location for ZNF101 Gene

Start:
19,668,153 bp from pter
End:
19,683,509 bp from pter
Size:
15,357 bases
Orientation:
Plus strand

Genomic View for ZNF101 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF101 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF101 Gene

Regulatory Elements for ZNF101 Gene

Proteins for ZNF101 Gene

  • Protein details for ZNF101 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IZC7-ZN101_HUMAN
    Recommended name:
    Zinc finger protein 101
    Protein Accession:
    Q8IZC7
    Secondary Accessions:
    • C9JU83
    • Q0VDG9

    Protein attributes for ZNF101 Gene

    Size:
    436 amino acids
    Molecular mass:
    50339 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF101 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF101 Gene

Proteomics data for ZNF101 Gene at MOPED

Post-translational modifications for ZNF101 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys62

Other Protein References for ZNF101 Gene

No data available for DME Specific Peptides for ZNF101 Gene

Domains for ZNF101 Gene

Gene Families for ZNF101 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZN101_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q8IZC7
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q8IZC7
Similarity:
  • Contains 10 C2H2-type zinc fingers.:
    • Q8IZC7
genes like me logo Genes that share domains with ZNF101: view

Function for ZNF101 Gene

Molecular function for ZNF101 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF101: view

miRNA for ZNF101 Gene

miRTarBase miRNAs that target ZNF101

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF101 Gene

Localization for ZNF101 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF101 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF101 Gene COMPARTMENTS Subcellular localization image for ZNF101 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF101: view

Pathways for ZNF101 Gene

SuperPathways for ZNF101 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF101: view

Pathways by source for ZNF101 Gene

2 Reactome pathways for ZNF101 Gene

Gene Ontology (GO) - Biological Process for ZNF101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF101: view

Transcripts for ZNF101 Gene

Unigene Clusters for ZNF101 Gene

Zinc finger protein 101:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF101 Gene

ExUns: 1 ^ 2 ^ 3a · 3b
SP1:
SP2:

Relevant External Links for ZNF101 Gene

GeneLoc Exon Structure for
ZNF101
ECgene alternative splicing isoforms for
ZNF101

Expression for ZNF101 Gene

mRNA expression in normal human tissues for ZNF101 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF101 Gene

This gene is overexpressed in Whole Blood (5.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF101 Gene

SOURCE GeneReport for Unigene cluster for ZNF101 Gene Hs.631642

mRNA Expression by UniProt/SwissProt for ZNF101 Gene

Q8IZC7-ZN101_HUMAN
Tissue specificity: Expressed in a variety of adult and fetal tissues.
genes like me logo Genes that share expressions with ZNF101: view

Orthologs for ZNF101 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF101 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF101 36
  • 99.31 (n)
  • 99.08 (a)
ZNF101 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 50 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp961 37
  • 36 (a)
ManyToMany
Species with no ortholog for ZNF101:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF101 Gene

ENSEMBL:
Gene Tree for ZNF101 (if available)
TreeFam:
Gene Tree for ZNF101 (if available)

Paralogs for ZNF101 Gene

Selected SIMAP similar genes for ZNF101 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for ZNF101 Gene

genes like me logo Genes that share paralogs with ZNF101: view

Variants for ZNF101 Gene

Sequence variations from dbSNP and Humsavar for ZNF101 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1529714 -- 19,682,675(+) ATTTT(A/G)GTTTT utr-variant-3-prime
rs2304130 -- 19,678,719(+) TCTAC(A/G)TTTTA intron-variant
rs4808209 - 19,679,350(+) GGCAC(A/C)TGAGA reference, missense
rs5827456 -- 19,683,587(+) TCCCC(-/T)TTTTT intron-variant
rs7248802 -- 19,672,676(+) acctg(C/T)cacca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF101 Gene

Variant ID Type Subtype PubMed ID
nsv911309 CNV Loss 21882294
nsv911310 CNV Loss 21882294
esv2659968 CNV Deletion 23128226
nsv519533 CNV Gain 19592680

Relevant External Links for ZNF101 Gene

HapMap Linkage Disequilibrium report
ZNF101

Disorders for ZNF101 Gene

Relevant External Links for ZNF101

Genetic Association Database (GAD)
ZNF101
genes like me logo Genes that share disorders with ZNF101: view

No data available for UniProtKB/Swiss-Prot for ZNF101 Gene

Publications for ZNF101 Gene

  1. Human chromosome 19 and related regions in mouse: conservative and lineage-specific evolution. (PMID: 11441184) Dehal P. … Stubbs L. (Science 2001) 2 3
  2. A novel Kruppel-associated box identified in a panel of mammalian zinc finger proteins. (PMID: 14727140) Looman C. … Abrink M. (Mamm. Genome 2004) 3 4
  3. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. (PMID: 22359512) Demirkan A. … Schmitz G. (PLoS Genet. 2012) 3 49
  4. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (PMID: 19060911) Aulchenko Y.S. … Peltonen L. (Nat. Genet. 2009) 3 49
  5. Genetic variants influencing circulating lipid levels and risk of coronary artery disease. (PMID: 20864672) Waterworth D.M. … Sandhu M.S. (Arterioscler. Thromb. Vasc. Biol. 2010) 3 49

Products for ZNF101 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF101
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF101
    • Block miRNA regulation of ZNF101 using miScript Target Protectors

    Sources for ZNF101 Gene

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