ZNF100 Gene

Aliases
for ZNF100 gene

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Previous GC identifers: GC19U990120 GC19M021697 GC19M021446

Summaries
for ZNF100 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Genomic Views
for ZNF100 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:

NC_000019.9  NT_011295.12  NC_018930.2  

SwitchGear Promoter luciferase reporter plasmid: ZNF100 promoter sequence

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF100

ZNF100 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M021906:  view genomic region     (about GC identifiers)

Proteins
for ZNF100 gene

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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Explore the universe of human proteins at neXtProt for ZNF100: NX_Q8IYN0

Explore proteomics data for ZNF100 at MOPED

Post-translational modifications: 

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Domains /
Families
for ZNF100 gene

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: Q8IYN0

Find genes that share domains with ZNF100           About GenesLikeMe

Function
for ZNF100 gene

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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     Gene Ontology (GO): 3 molecular function terms:    About this table

genOway: Develop your customized and physiologically relevant rodent model for ZNF100

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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF100

Localization
for ZNF100 gene

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

Compartment	Confidence
nucleus	4
cytosol	2

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Gene Ontology (GO): 2 cellular component terms:    About this table

Pathways & Interactions
for ZNF100 gene

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for ZNF100 About     See pathways by source

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	SuperPath	Contained pathways About
1	Gene Expression	Generic Transcription Pathway 0.40 Gene Expression 0.40

1 Reactome Pathway for ZNF100

Generic Transcription Pathway

Gene Ontology (GO): 2 biological process terms:    About this table

Drugs & Compounds
for ZNF100 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Transcripts
for ZNF100 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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Expression
for ZNF100 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ZNF100 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: ATAGACCCCT

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Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for ZNF100
		Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ZNF100
		QuantiTect SYBR Green Assays in human, mouse, rat ZNF100
		QuantiFast Probe-based Assays in human, mouse, rat ZNF100

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF100

Orthologs
for ZNF100 gene

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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Paralogs
for ZNF100 gene

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for ZNF100 gene

ZNF85²  ZNF486²  ZNF195²  ZNF92²  ZNF732²  ZNF675²  ZNF138²  ZNF506²  

ZNF66²  ZNF273²  ZNF695²  ZNF626²  ZNF680²  ZNF479²  ZNF253²  ZNF93²  

ZNF682²  ZNF492²  ZNF676²  ZNF681²  ZNF141²  ZNF736²  ZNF679²  ZNF257²  

ZNF254²  ZNF737²  ZNF724P²  ZNF98²  ZNF716²  ZNF714²  ZNF429²  ZNF519²  

ZNF430²  ZNF730²  ZNF117²  ZNF708²  ZNF431²  ZNF90²  ZNF726²  ZNF728²  

Selected SIMAP similar genes for ZNF100 using alignment to 4 protein entries:     ZN100_HUMAN (see all proteins) (see all similar genes):

DKFZp686M04222    MGC12518    ZNF724P    ZNF273    ZNF98    ZNF257

ZNF818P    ZNF506    ZNF90    ZNF730    ZNF430    ZNF429

ERBB2    ZFS-6    ZNF43    ZNF492    ZNF675    ZNF738

Find genes that share paralogs with ZNF100           About GenesLikeMe


1 Pseudogenes.org Pseudogene for ZNF100
PGOHUM00000234606

Genomic Variants
for ZNF100 gene

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ZNF100 (see all 1048)    About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1435746971,2	C	--	21449069(+)	ATGAA-/TTATC          TTATG	1	--	ut31		0	--	--	--	--
rs37952471,2	C,F,H	--	21906428(+)	CCACAT/CGAAGA	1	--	int1		15		EA NA NS CSA WA	2374
rs1490235021,2		--	21906466(+)	TTTTCA/CATCTC	1	--	int1		0	--	--	--	--
rs1114682211,2	F	--	21906612(+)	TAGTAG/CTTACC	1	--	int1		2		CSA	4
rs345047421,2	C,F,H	--	21906655(+)	ATGTCA/GACTAT	1	--	int1		4		NS NA	232
rs796810711,2	C,F	--	21906685(+)	AACTAA/CAGGGC	1	--	int1		3		NA	124
rs1866284191,2		--	21906747(+)	GTAACC/TTAATA	1	--	int1		0	--	--	--	--
rs1915220081,2		--	21906787(+)	TTGTAG/TGCACT	1	--	int1		0	--	--	--	--
rs1840877451,2		--	21906836(+)	TCACAA/TAATGA	1	--	int1		0	--	--	--	--
rs1888241151,2		--	21906880(+)	AAAGAC/TACAAA	1	--	ut31		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZNF100 (21905568 - 21950430 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for ZNF100 (see all 13):    About this table    

Variant ID	Type	Subtype	PubMed ID
esv2718343	CNV	Deletion	23290073
esv2675419	CNV	Deletion	23128226
dgv552e201	CNV	Deletion	23290073
esv2718335	CNV	Deletion	23290073
nsv833783	CNV	Loss	17160897
esv2578515	CNV	Loss	19546169
nsv833784	CNV	Loss	17160897
nsv911422	CNV	Loss	21882294
dgv3808n71	CNV	Gain	21882294
dgv3809n71	CNV	Gain	21882294

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing ZNF100

DNA2.0 Custom Variant and Variant Library Synthesis for ZNF100

Disorders / Diseases
for ZNF100 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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Publications
for ZNF100 gene

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ZNF100 gene integrated from 10 sources: (articles sorted by number of sources associating them with ZNF100)

Utopia: connect your pdf to the dynamic world of online information

1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{1, 3} Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (amp 2012)
4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (Genome Res. 2006)
5. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)² Grimwood J.... Lucas S.M. (Nature 2004)
6. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)¹ Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)
7. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PubMed id 8467795)¹ Bellefroid E.J.... Martial J.A. (EMBO J. 1993)
8. High-resolution localization of 69 potential human zinc finger protein genes: a number are clustered. (PubMed id 1740334)² Hoovers J.M.N.... Little P.F.R. (Genomics 1992)

External Searches for ZNF100 gene

Genome Databases showing ZNF100 gene

Other Databases showing ZNF100 gene

Specialized Databases showing ZNF100 gene

Products
for ZNF100 gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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