ZNF100 Gene
protein-coding GIFtS: 45
GCID: GC19M021906
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|
zinc finger protein 100(Previous name: zinc finger protein 100 (Y1) )
| |
Aliases
for ZNF100 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 1001 2 | | Zinc Finger Protein 100 (Y1)1 2 |
Export aliases for ZNF100 gene to outside databasesPrevious GC identifers: GC19U990120 GC19M021697 GC19M021446 |
Summaries
for ZNF100 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN100_HUMAN, Q8IYN0Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF100 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZNF100
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF100
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF100 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p12 Ensembl cytogenetic band: 19p12 HGNC cytogenetic band: 19p13.1ZNF100 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M021906: view genomic region
(about GC identifiers)
Start:
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21,905,568 bp from pter |
End:
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21,950,430 bp from pter |
Size:
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44,863 bases |
Orientation:
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minus strand |
1 alternative location:
| Chr19-,PATCHES 21,911,582-21,955,169 |
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Proteins
for ZNF100 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN100_HUMAN, Q8IYN0 (See
protein sequence)Recommended Name: Zinc finger protein 100 Size: 542 amino acids; 62745 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q7M4M0Explore the universe of human proteins at neXtProt for ZNF100: NX_Q8IYN0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IYN0
ZNF100 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_775802.2
ENSEMBL proteins: ENSP00000351042 Reactome Protein details: Q8IYN0
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF100 for ontologies About GeneDecksing
ZNF100 Antibody Products:
Assay Products for ZNF100: |
Protein
Domains /
Families
for ZNF100 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF100 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IYN0ProtoNet protein and cluster: Q8IYN0 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN100_HUMAN, Q8IYN0Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 12 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF100 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN100_HUMAN, Q8IYN0Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF100
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF100
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ZNF100 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF100 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF100 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF100 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF100
ZNF100 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF100
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF100 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF100 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF100
Search CenterWatch for drugs/clinical trials and news about ZNF100 / ZN100
|
Transcripts
for ZNF100 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF100 gene: NM_173531.3 Unigene Cluster for ZNF100: Zinc finger protein 100 Hs.365142 [show with all ESTs]Unigene Representative Sequence: BC0355791 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000358296(uc002nqh.3 uc002nqi.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF100
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF100
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF100 (NM_173531) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF100 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF100 |
Additional cDNA sequence: AK126551.1 AK308798.1 BC031248.1 BC035579.1 BX640982.1 7 DOTS entries: DT.95071826 DT.101976780 DT.121421774 DT.75122213 DT.100799832 DT.121421758 DT.91873758 24/52 AceView cDNA sequences (see all 52): H54456 BX640982 AA282536 BM471621 CB146744 BM466181 AA282641 AW515912 BQ436588 AA580396 BX426165 AI818947 BG503950 NM_173531 AI818966 BX508716 BX414754 AK126551 BX107586 BX404682 BG285112 AA319414 BC031248 CD688588
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF100 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c |
|---|
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| SP1: | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF100
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Expression
for ZNF100 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF100 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATAGACCCCT
About this image
See ZNF100 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF100
SOURCE GeneReport for Unigene cluster: Hs.365142
SABiosciences Custom PCR Arrays for ZNF100
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF100
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF100 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF100 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF100 |
Orthologs
for ZNF100 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF100 gene from 1/4 species (see all 4) About this table
ENSEMBL Gene Tree for ZNF100 (if available)
TreeFam Gene Tree for ZNF100 (if available) |
Paralogs
for ZNF100 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF100 gene
- ZNF852 ZNF4932 ZNF4862 ZNF922 ZNF7322 ZNF1382 ZNF6752 ZNF5062
- ZNF2732 ZNF66P2 ZNF6952 ZNF6262 ZNF6802 ZNF2532 ZNF4792 ZNF932
- ZNF4922 ZNF6822 ZNF6762 ZNF1412 ZNF6812 ZNF6792 ZNF2572 ZNF2542
- ZNF7372 ZNF724P2 ZNF982 ZNF849P2 ZNF7162 ZNF7142 ZNF4292 ZNF4302
- ZNF7302 ZNF6782 ZNF1172 ZNF7082 ZNF1072 ZNF4312 ZNF902
18/507 SIMAP similar genes for ZNF100 using alignment to 4 protein entries: ZN100_HUMAN (see all proteins)
(see all similar genes):DKFZp686M04222 MGC12518 ZNF818P ZNF273 ZNF738 ZFS-6
ZNF492 ZNF98 ZNF85 ZNF66 ZNF430 ZNF737
ZNF429 ZNF724P ZNF93 ZNF708 ZNF726 ZNF78L1
ZNF100 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ZNF100
PGOHUM00000234606
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Genomic Variants
for ZNF100 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF100 (21905568 - 21950430 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZNF100
2 Inversions: 59910 37202 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF100 |
|
Disorders
/ Diseases
for ZNF100 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF100 for disorders About MalaCards
ZNF100 for disorders About GeneDecksing
OMIM gene information: 603982
OMIM disorders: --
Export disorders for ZNF100 gene to outside databases
|
Publications
for ZNF100 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF100 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF100) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
- Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PubMed id 8467795)1 Bellefroid E.J.... Martial J.A. (1993)
- High-resolution localization of 69 potential human zinc finger protein genes: a number are clustered. (PubMed id 1740334)2 Hoovers J.M.... Little P.F. (1992)
|
External Searches for ZNF100 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF100 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF100 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF100 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF100 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF100 gene:
Search GeneIP for patents involving ZNF100
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF100 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF100 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF100 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF100 | | | OriGene Protein Over-expression Lysate for ZNF100 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF100 | | OriGene 3'-UTR Clone for ZNF100 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF100 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF100 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF100 | | OriGene Custom Protein Services for ZNF100 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF100 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF100 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF100 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF100 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF100 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF100 |
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 | | | ZNF100 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | ThermoFisher Antibodies for ZNF100 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF100 |
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