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Aliases for ZNF100 Gene

Aliases for ZNF100 Gene

  • Zinc Finger Protein 100 2 3 5
  • Zinc Finger Protein 100 (Y1) 2

External Ids for ZNF100 Gene

Previous GeneCards Identifiers for ZNF100 Gene

  • GC19U990120
  • GC19M021697
  • GC19M021906
  • GC19M021446

Summaries for ZNF100 Gene

GeneCards Summary for ZNF100 Gene

ZNF100 (Zinc Finger Protein 100) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF718.

UniProtKB/Swiss-Prot for ZNF100 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF100 Gene

Genomics for ZNF100 Gene

Regulatory Elements for ZNF100 Gene

Promoters for ZNF100 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF100 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF100 Gene

Chromosome:
19
Start:
21,722,766 bp from pter
End:
21,767,628 bp from pter
Size:
44,863 bases
Orientation:
Minus strand

Genomic View for ZNF100 Gene

Genes around ZNF100 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF100 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF100 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF100 Gene

Proteins for ZNF100 Gene

  • Protein details for ZNF100 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IYN0-ZN100_HUMAN
    Recommended name:
    Zinc finger protein 100
    Protein Accession:
    Q8IYN0
    Secondary Accessions:
    • Q7M4M0

    Protein attributes for ZNF100 Gene

    Size:
    542 amino acids
    Molecular mass:
    62745 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF100 Gene

Proteomics data for ZNF100 Gene at MOPED

Post-translational modifications for ZNF100 Gene

  • Ubiquitination at Lys 12
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF100 Gene

No data available for DME Specific Peptides for ZNF100 Gene

Domains & Families for ZNF100 Gene

Gene Families for ZNF100 Gene

Protein Domains for ZNF100 Gene

Suggested Antigen Peptide Sequences for ZNF100 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IYN0

UniProtKB/Swiss-Prot:

ZN100_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF100: view

Function for ZNF100 Gene

Molecular function for ZNF100 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF100: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF100 Gene

Localization for ZNF100 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF100 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF100 Gene COMPARTMENTS Subcellular localization image for ZNF100 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF100 Gene

Pathways & Interactions for ZNF100 Gene

SuperPathways for ZNF100 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF100: view

Pathways by source for ZNF100 Gene

2 Reactome pathways for ZNF100 Gene

Interacting Proteins for ZNF100 Gene

Gene Ontology (GO) - Biological Process for ZNF100 Gene

None

No data available for SIGNOR curated interactions for ZNF100 Gene

Drugs & Compounds for ZNF100 Gene

No Compound Related Data Available

Transcripts for ZNF100 Gene

Unigene Clusters for ZNF100 Gene

Zinc finger protein 100:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF100 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c
SP1: -
SP2: -
SP3: - - -
SP4:

Relevant External Links for ZNF100 Gene

GeneLoc Exon Structure for
ZNF100
ECgene alternative splicing isoforms for
ZNF100

Expression for ZNF100 Gene

mRNA expression in normal human tissues for ZNF100 Gene

Protein differential expression in normal tissues from HIPED for ZNF100 Gene

This gene is overexpressed in Islet of Langerhans (46.6) and Serum (22.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF100 Gene



SOURCE GeneReport for Unigene cluster for ZNF100 Gene Hs.365142

genes like me logo Genes that share expression patterns with ZNF100: view

Protein tissue co-expression partners for ZNF100 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF100 Gene

Orthologs for ZNF100 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF100 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 50 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 36 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 35 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp493 36
  • 58 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia ZNF100 36
  • 100 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 48 (a)
ManyToMany
-- 36
  • 32 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 36 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 27 (a)
ManyToMany
Species with no ortholog for ZNF100:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF100 Gene

ENSEMBL:
Gene Tree for ZNF100 (if available)
TreeFam:
Gene Tree for ZNF100 (if available)

Paralogs for ZNF100 Gene

(531) SIMAP similar genes for ZNF100 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for ZNF100 Gene

genes like me logo Genes that share paralogs with ZNF100: view

Variants for ZNF100 Gene

Sequence variations from dbSNP and Humsavar for ZNF100 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
VAR_057395 -
VAR_060422 -

Structural Variations from Database of Genomic Variants (DGV) for ZNF100 Gene

Variant ID Type Subtype PubMed ID
esv4924 CNV Complex 18987735
esv2718335 CNV Deletion 23290073
dgv552e201 CNV Deletion 23290073
nsv911422 CNV Loss 21882294
nsv7306 OTHER Inversion 18451855
dgv3808n71 CNV Gain 21882294
esv2718343 CNV Deletion 23290073
nsv833783 CNV Loss 17160897
dgv73e19 OTHER Inversion 19470904
dgv3809n71 CNV Gain 21882294
nsv833784 CNV Loss 17160897
esv2578515 CNV Loss 19546169
esv2675419 CNV Deletion 23128226

Variation tolerance for ZNF100 Gene

Residual Variation Intolerance Score: 69.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.39; 63.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF100 Gene

HapMap Linkage Disequilibrium report
ZNF100

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF100 Gene

Disorders for ZNF100 Gene

Relevant External Links for ZNF100

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF100

No disorders were found for ZNF100 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF100 Gene

Publications for ZNF100 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PMID: 8467795) Bellefroid E.J. … Martial J.A. (EMBO J. 1993) 3

Products for ZNF100 Gene

Sources for ZNF100 Gene

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