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Aliases for ZNF100 Gene

Aliases for ZNF100 Gene

  • Zinc Finger Protein 100 2 3
  • Zinc Finger Protein 100 (Y1) 2

External Ids for ZNF100 Gene

Summaries for ZNF100 Gene

GeneCards Summary for ZNF100 Gene

ZNF100 (Zinc Finger Protein 100) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF100 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF100 Gene

Genomics for ZNF100 Gene

Genomic Location for ZNF100 Gene

Start:
21,722,766 bp from pter
End:
21,767,628 bp from pter
Size:
44,863 bases
Orientation:
Minus strand

Genomic View for ZNF100 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF100 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF100 Gene

No data available for Regulatory Elements for ZNF100 Gene

Proteins for ZNF100 Gene

  • Protein details for ZNF100 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IYN0-ZN100_HUMAN
    Recommended name:
    Zinc finger protein 100
    Protein Accession:
    Q8IYN0
    Secondary Accessions:
    • Q7M4M0

    Protein attributes for ZNF100 Gene

    Size:
    542 amino acids
    Molecular mass:
    62745 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF100 Gene

Proteomics data for ZNF100 Gene at MOPED

Post-translational modifications for ZNF100 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys12 and Lys346

Other Protein References for ZNF100 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF100 Gene

Domains for ZNF100 Gene

Gene Families for ZNF100 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZN100_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q8IYN0
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q8IYN0
Similarity:
  • Contains 12 C2H2-type zinc fingers.:
    • Q8IYN0
genes like me logo Genes that share domains with ZNF100: view

Function for ZNF100 Gene

Molecular function for ZNF100 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF100 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF100: view

miRNA for ZNF100 Gene

miRTarBase miRNAs that target ZNF100

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF100 Gene

Localization for ZNF100 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF100 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF100 Gene COMPARTMENTS Subcellular localization image for ZNF100 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF100 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF100: view

Pathways for ZNF100 Gene

SuperPathways for ZNF100 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF100: view

Pathways by source for ZNF100 Gene

2 Reactome pathways for ZNF100 Gene

Interacting Proteins for ZNF100 Gene

Gene Ontology (GO) - Biological Process for ZNF100 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF100: view

Transcripts for ZNF100 Gene

Unigene Clusters for ZNF100 Gene

Zinc finger protein 100:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF100 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c
SP1: -
SP2: -
SP3: - - -
SP4:

Relevant External Links for ZNF100 Gene

GeneLoc Exon Structure for
ZNF100
ECgene alternative splicing isoforms for
ZNF100

Expression for ZNF100 Gene

mRNA expression in normal human tissues for ZNF100 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF100 Gene

SOURCE GeneReport for Unigene cluster for ZNF100 Gene Hs.365142

genes like me logo Genes that share expressions with ZNF100: view

Orthologs for ZNF100 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF100 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF100 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 50 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 36 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp493 37
  • 58 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 35 (a)
ManyToMany
-- 37
  • 47 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 48 (a)
ManyToMany
-- 37
  • 32 (a)
ManyToMany
-- 37
  • 39 (a)
ManyToMany
-- 37
  • 36 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 27 (a)
ManyToMany
Species with no ortholog for ZNF100:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF100 Gene

ENSEMBL:
Gene Tree for ZNF100 (if available)
TreeFam:
Gene Tree for ZNF100 (if available)

Paralogs for ZNF100 Gene

Selected SIMAP similar genes for ZNF100 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for ZNF100 Gene

genes like me logo Genes that share paralogs with ZNF100: view

Variants for ZNF100 Gene

Sequence variations from dbSNP and Humsavar for ZNF100 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1064126 -- 21,724,480(-) CATTT(C/T)TGAGG utr-variant-3-prime
rs2203944 -- 21,725,791(+) TTCTA(C/T)ACTCA utr-variant-3-prime
rs3081586 -- 21,725,877(-) aatCA(-/AAAA/AATA)TTAAG utr-variant-3-prime
rs3795247 -- 21,723,626(+) CCACA(C/T)GAAGA intron-variant, utr-variant-3-prime
rs4130935 -- 21,741,742(-) gccat(A/G)attgt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF100 Gene

Variant ID Type Subtype PubMed ID
esv4924 CNV Complex 18987735
esv2718335 CNV Deletion 23290073
dgv552e201 CNV Deletion 23290073
nsv911422 CNV Loss 21882294
nsv7306 OTHER Inversion 18451855
dgv3808n71 CNV Gain 21882294
esv2718343 CNV Deletion 23290073
nsv833783 CNV Loss 17160897
dgv73e19 OTHER Inversion 19470904
dgv3809n71 CNV Gain 21882294
nsv833784 CNV Loss 17160897
esv2578515 CNV Loss 19546169
esv2675419 CNV Deletion 23128226

Relevant External Links for ZNF100 Gene

HapMap Linkage Disequilibrium report
ZNF100

Disorders for ZNF100 Gene

No disorders were found for ZNF100 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF100 Gene

Publications for ZNF100 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  4. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PMID: 8467795) Bellefroid E.J. … Martial J.A. (EMBO J. 1993) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF100 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF100
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF100
    • Block miRNA regulation of ZNF100 using miScript Target Protectors

    Sources for ZNF100 Gene

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