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Aliases for ZMYND12 Gene

Aliases for ZMYND12 Gene

  • Zinc Finger MYND-Type Containing 12 2 3 5

External Ids for ZMYND12 Gene

Previous GeneCards Identifiers for ZMYND12 Gene

  • GC01M042359
  • GC01M042309
  • GC01M042565
  • GC01M042668
  • GC01M042896
  • GC01M041016

Summaries for ZMYND12 Gene

GeneCards Summary for ZMYND12 Gene

ZMYND12 (Zinc Finger MYND-Type Containing 12) is a Protein Coding gene.

Additional gene information for ZMYND12 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZMYND12 Gene

Genomics for ZMYND12 Gene

GeneHancer (GH) Regulatory Elements for ZMYND12 Gene

Promoters and enhancers for ZMYND12 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I042454 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.4 399 3.6 HDGF PKNOX1 SMAD1 ARID4B SIN3A DMAP1 IRF4 YY1 POLR2B ZNF213 PPCS ZMYND12 CCDC30 FOXJ3 PPIH PIR31959
GH01I042461 Promoter/Enhancer 1.4 Ensembl ENCODE 14.5 -6.8 -6774 2.2 PKNOX1 ARID4B SIN3A ZNF48 YY1 ELK1 ZNF207 ZNF143 RUNX3 SP3 CCDC30 SZT2 ZMYND12 P3H1 PPCS
GH01I042784 Enhancer 0.7 FANTOM5 Ensembl 25.5 -329.0 -328974 1.1 PKNOX1 ZBTB33 TMEM269 LOC105378683 SVBP ZMYND12 CFAP57 YBX1 ENSG00000283580 GC01M042733
GH01I042419 Enhancer 0.7 ENCODE 24.7 +35.8 35773 2.6 ZBTB6 NFIB FEZF1 ZIC2 ZNF335 POLR2A ZBTB48 PATZ1 PRDM10 RCOR1 ZMYND12 SVBP PPIH PPCS RNU6-536P ENSG00000236180 CLDN19 YBX1 PIR31959 RIMKLA
GH01I042529 Enhancer 0.8 Ensembl ENCODE 20.6 -73.8 -73772 1.7 IRF2 CEBPB CEBPG FOSL1 ZNF766 IKZF1 SCRT2 NFE2 ZNF24 FOS ZMYND12 RNU6-536P ENSG00000236180 PPIH GC01P042512 GC01M042556 CCDC30
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZMYND12 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZMYND12 gene promoter:

Genomic Locations for ZMYND12 Gene

Genomic Locations for ZMYND12 Gene
chr1:42,430,329-42,456,267
(GRCh38/hg38)
Size:
25,939 bases
Orientation:
Minus strand
chr1:42,896,000-42,921,938
(GRCh37/hg19)

Genomic View for ZMYND12 Gene

Genes around ZMYND12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZMYND12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZMYND12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZMYND12 Gene

Proteins for ZMYND12 Gene

  • Protein details for ZMYND12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0C1-ZMY12_HUMAN
    Recommended name:
    Zinc finger MYND domain-containing protein 12
    Protein Accession:
    Q9H0C1
    Secondary Accessions:
    • Q5VUS6
    • Q8TC87
    • Q96M51

    Protein attributes for ZMYND12 Gene

    Size:
    365 amino acids
    Molecular mass:
    41818 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZMYND12 Gene

Post-translational modifications for ZMYND12 Gene

No Post-translational modifications

Other Protein References for ZMYND12 Gene

No data available for DME Specific Peptides for ZMYND12 Gene

Domains & Families for ZMYND12 Gene

Gene Families for ZMYND12 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZMYND12 Gene

Suggested Antigen Peptide Sequences for ZMYND12 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZMYND12: view

No data available for UniProtKB/Swiss-Prot for ZMYND12 Gene

Function for ZMYND12 Gene

Gene Ontology (GO) - Molecular Function for ZMYND12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZMYND12: view
genes like me logo Genes that share phenotypes with ZMYND12: view

Animal Model Products

miRNA for ZMYND12 Gene

miRTarBase miRNAs that target ZMYND12

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZMYND12 Gene

Localization for ZMYND12 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZMYND12 gene
Compartment Confidence
nucleus 2
cytosol 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for ZMYND12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IDA --
genes like me logo Genes that share ontologies with ZMYND12: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for ZMYND12 Gene

Pathways & Interactions for ZMYND12 Gene

SuperPathways for ZMYND12 Gene

No Data Available

Interacting Proteins for ZMYND12 Gene

Selected Interacting proteins: Q9H0C1-ZMY12_HUMAN for ZMYND12 Gene via UniProtKB

Gene Ontology (GO) - Biological Process for ZMYND12 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZMYND12 Gene

Drugs & Compounds for ZMYND12 Gene

No Compound Related Data Available

Transcripts for ZMYND12 Gene

Unigene Clusters for ZMYND12 Gene

Zinc finger, MYND-type containing 12:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZMYND12 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9
SP1: - - -
SP2: -
SP3:
SP4:

Relevant External Links for ZMYND12 Gene

GeneLoc Exon Structure for
ZMYND12
ECgene alternative splicing isoforms for
ZMYND12

Expression for ZMYND12 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZMYND12 Gene

mRNA differential expression in normal tissues according to GTEx for ZMYND12 Gene

This gene is overexpressed in Testis (x11.1).

Protein differential expression in normal tissues from HIPED for ZMYND12 Gene

This gene is overexpressed in Plasma (57.9) and Ovary (11.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZMYND12 Gene



Protein tissue co-expression partners for ZMYND12 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZMYND12 Gene:

ZMYND12

SOURCE GeneReport for Unigene cluster for ZMYND12 Gene:

Hs.294009
genes like me logo Genes that share expression patterns with ZMYND12: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZMYND12 Gene

Orthologs for ZMYND12 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZMYND12 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZMYND12 33 34
  • 99.36 (n)
cow
(Bos Taurus)
Mammalia ZMYND12 33 34
  • 88.58 (n)
dog
(Canis familiaris)
Mammalia ZMYND12 33 34
  • 87.12 (n)
rat
(Rattus norvegicus)
Mammalia Zmynd12 33
  • 84.16 (n)
mouse
(Mus musculus)
Mammalia Zmynd12 33 16 34
  • 83.89 (n)
oppossum
(Monodelphis domestica)
Mammalia ZMYND12 34
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZMYND12 34
  • 57 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZMYND12 33
  • 60.54 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia zmynd12 33
  • 61.43 (n)
Str.3332 33
zebrafish
(Danio rerio)
Actinopterygii zymnd12 33 34
  • 51.5 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3655 34
  • 37 (a)
OneToOne
Species where no ortholog for ZMYND12 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZMYND12 Gene

ENSEMBL:
Gene Tree for ZMYND12 (if available)
TreeFam:
Gene Tree for ZMYND12 (if available)

Paralogs for ZMYND12 Gene

No data available for Paralogs for ZMYND12 Gene

Variants for ZMYND12 Gene

Sequence variations from dbSNP and Humsavar for ZMYND12 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000004996 -- 42,438,845(-) G/A/T intron_variant
rs1000071534 -- 42,437,415(-) TTTT/TTT intron_variant
rs1000258260 -- 42,447,838(-) C/G intron_variant
rs1000346565 -- 42,432,229(-) T/G intron_variant
rs1000546667 -- 42,456,445(-) T/C/G upstream_transcript_variant

Variation tolerance for ZMYND12 Gene

Residual Variation Intolerance Score: 66.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.91; 35.60% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZMYND12 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZMYND12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZMYND12 Gene

Disorders for ZMYND12 Gene

Additional Disease Information for ZMYND12

No disorders were found for ZMYND12 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZMYND12 Gene

Publications for ZMYND12 Gene

  1. Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 2 3 4 58
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ZMYND12 Gene

Sources for ZMYND12 Gene

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