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Aliases for ZMYM6 Gene

Aliases for ZMYM6 Gene

  • Zinc Finger, MYM-Type 6 2 3
  • Zinc Finger Protein 258 2 3 4
  • ZNF258 3 4 6
  • Transposon-Derived Buster2 Transposase-Like Protein 3 4
  • Zinc Finger, MYM-Type Containing 6 2 3
  • Buster2 3 4
  • Zinc Finger, BED-Type Containing 7 3
  • Zinc Finger MYM-Type Protein 6 3
  • BED-Type Containing 7 2
  • Zinc Finger 2
  • ZNF198L4 3
  • KIAA1353 4
  • ZBED7 3
  • MYM 3

External Ids for ZMYM6 Gene

Previous Symbols for ZMYM6 Gene

  • ZNF258

Summaries for ZMYM6 Gene

GeneCards Summary for ZMYM6 Gene

ZMYM6 (Zinc Finger, MYM-Type 6) is a Protein Coding gene. An important paralog of this gene is ZMYM4.

UniProtKB/Swiss-Prot for ZMYM6 Gene

  • Plays a role in the regulation of cell morphology and cytoskeletal organization.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZMYM6 Gene

Genomics for ZMYM6 Gene

Genomic Location for ZMYM6 Gene

Start:
34,986,165 bp from pter
End:
35,031,968 bp from pter
Size:
45,804 bases
Orientation:
Minus strand

Genomic View for ZMYM6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZMYM6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZMYM6 Gene

Regulatory Elements for ZMYM6 Gene

Proteins for ZMYM6 Gene

  • Protein details for ZMYM6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95789-ZMYM6_HUMAN
    Recommended name:
    Zinc finger MYM-type protein 6
    Protein Accession:
    O95789
    Secondary Accessions:
    • B4DRJ6
    • Q32Q23
    • Q4G108
    • Q5SVZ9
    • Q5SW00
    • Q69YL4
    • Q96IY0
    • Q9NWF1
    • Q9P2J4

    Protein attributes for ZMYM6 Gene

    Size:
    1325 amino acids
    Molecular mass:
    148089 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH33903.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAI07881.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAA92591.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZMYM6 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZMYM6 Gene

Proteomics data for ZMYM6 Gene at MOPED

Post-translational modifications for ZMYM6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZMYM6 Gene

No data available for DME Specific Peptides for ZMYM6 Gene

Domains for ZMYM6 Gene

Gene Families for ZMYM6 Gene

HGNC:
  • ZMYM :Zinc fingers, MYM type
  • ZBED :Zinc fingers, BED-type

Protein Domains for ZMYM6 Gene

Suggested Antigen Peptide Sequences for ZMYM6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O95789

UniProtKB/Swiss-Prot:

ZMYM6_HUMAN
Similarity:
  • Contains 8 MYM-type zinc fingers.:
    • O95789
genes like me logo Genes that share domains with ZMYM6: view

Function for ZMYM6 Gene

Molecular function for ZMYM6 Gene

UniProtKB/Swiss-Prot Function: Plays a role in the regulation of cell morphology and cytoskeletal organization.

Gene Ontology (GO) - Molecular Function for ZMYM6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding TAS 10486218
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZMYM6: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZMYM6 Gene

Localization for ZMYM6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZMYM6 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZMYM6 Gene COMPARTMENTS Subcellular localization image for ZMYM6 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZMYM6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZMYM6: view

Pathways for ZMYM6 Gene

SuperPathways for ZMYM6 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZMYM6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007010 cytoskeleton organization IMP 21834987
GO:0007275 multicellular organismal development TAS 10486218
GO:0022604 regulation of cell morphogenesis IMP 21834987
genes like me logo Genes that share ontologies with ZMYM6: view

No data available for Pathways by source for ZMYM6 Gene

Transcripts for ZMYM6 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for ZMYM6 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a ·
SP1: - - - -
SP2: - - -
SP3: - -
SP4: - -
SP5:
SP6: - - -
SP7: - -
SP8: - - - - -
SP9:
SP10:
SP11:
SP12:

ExUns: 19b ^ 20a · 20b ^ 21a · 21b ^ 22 ^ 23a · 23b
SP1:
SP2: -
SP3:
SP4:
SP5:
SP6:
SP7: -
SP8:
SP9:
SP10:
SP11: - - - - -
SP12:

Relevant External Links for ZMYM6 Gene

GeneLoc Exon Structure for
ZMYM6
ECgene alternative splicing isoforms for
ZMYM6

Expression for ZMYM6 Gene

mRNA expression in normal human tissues for ZMYM6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZMYM6 Gene

SOURCE GeneReport for Unigene cluster for ZMYM6 Gene Hs.623978

mRNA Expression by UniProt/SwissProt for ZMYM6 Gene

O95789-ZMYM6_HUMAN
Tissue specificity: Expressed at high levels in heart, skeletal muscle, kidney and liver.
genes like me logo Genes that share expressions with ZMYM6: view

No data available for mRNA differential expression in normal tissues for ZMYM6 Gene

Orthologs for ZMYM6 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZMYM6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZMYM6 35
  • 99.82 (n)
  • 99.77 (a)
ZMYM6 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZMYM6 35
  • 90.09 (n)
  • 86.8 (a)
dog
(Canis familiaris)
Mammalia ZMYM6 35
  • 90.16 (n)
  • 87.96 (a)
ZMYM6 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zmym6 35
  • 76.91 (n)
  • 68.07 (a)
Zmym6 16
Zmym6 36
  • 71 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 38 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 45 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zmym6 35
  • 76.93 (n)
  • 67.42 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 38 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 52 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.555 35
zebrafish
(Danio rerio)
Actinopterygii si:ch211-173p18.3 36
  • 21 (a)
ManyToMany
si:ch211-266o15.1 36
  • 23 (a)
ManyToMany
zmym4 36
  • 22 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta woc 36
  • 11 (a)
OneToMany
Species with no ortholog for ZMYM6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZMYM6 Gene

ENSEMBL:
Gene Tree for ZMYM6 (if available)
TreeFam:
Gene Tree for ZMYM6 (if available)

Paralogs for ZMYM6 Gene

Paralogs for ZMYM6 Gene

Selected SIMAP similar genes for ZMYM6 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZMYM6: view

Variants for ZMYM6 Gene

Sequence variations from dbSNP and Humsavar for ZMYM6 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1065530 -- 35,014,797(-) CACCA(C/T)GAACT missense, reference
rs1065531 -- 35,010,861(-) TCTTG(C/G)TGAAC reference, missense
rs2151554 -- 35,002,828(-) TAGAA(C/T)AATGC intron-variant
rs2184188 -- 35,002,903(-) GAGCC(A/G)ATGGT intron-variant
rs3820462 -- 35,014,561(-) TGGGA(C/T)AGATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZMYM6 Gene

Variant ID Type Subtype PubMed ID
dgv213n71 CNV Loss 21882294
nsv870757 CNV Gain 21882294
nsv511093 CNV Complex 20534489
nsv508138 CNV Loss 20534489

Relevant External Links for ZMYM6 Gene

HapMap Linkage Disequilibrium report
ZMYM6
Human Gene Mutation Database (HGMD)
ZMYM6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZMYM6 Gene

Disorders for ZMYM6 Gene

(2) University of Copenhagen DISEASES for ZMYM6 Gene

genes like me logo Genes that share disorders with ZMYM6: view

No data available for UniProtKB/Swiss-Prot for ZMYM6 Gene

Publications for ZMYM6 Gene

  1. Cloning and mapping of members of the MYM family. (PMID: 10486218) Smedley D. … Shipley J. (Genomics 1999) 2 3 4
  2. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. (PMID: 21834987) Bai S.W. … Ridley A.J. (BMC Biol. 2011) 3 4

Products for ZMYM6 Gene

Sources for ZMYM6 Gene

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