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Aliases for ZMYM5 Gene

Aliases for ZMYM5 Gene

  • Zinc Finger, MYM-Type 5 2 3
  • Zinc Finger Protein 237 2 3 4
  • Zinc Finger Protein 198-Like 1 3 4
  • ZNF198L1 3 4
  • ZNF237 3 4
  • Zinc Finger MYM-Type Protein 5 3
  • HSPC050 3
  • MYM 3

External Ids for ZMYM5 Gene

Previous HGNC Symbols for ZMYM5 Gene

  • ZNF237

Previous GeneCards Identifiers for ZMYM5 Gene

  • GC13M019310
  • GC13M020397
  • GC13M001202

Summaries for ZMYM5 Gene

GeneCards Summary for ZMYM5 Gene

ZMYM5 (Zinc Finger, MYM-Type 5) is a Protein Coding gene. An important paralog of this gene is ZMYM6.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZMYM5 Gene

Genomics for ZMYM5 Gene

Regulatory Elements for ZMYM5 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZMYM5 Gene

Start:
19,823,481 bp from pter
End:
19,863,636 bp from pter
Size:
40,156 bases
Orientation:
Minus strand

Genomic View for ZMYM5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZMYM5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZMYM5 Gene

Proteins for ZMYM5 Gene

  • Protein details for ZMYM5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UJ78-ZMYM5_HUMAN
    Recommended name:
    Zinc finger MYM-type protein 5
    Protein Accession:
    Q9UJ78
    Secondary Accessions:
    • B2R6V1
    • Q5T6E1
    • Q5T6E2
    • Q5T6E4
    • Q96IY6
    • Q9NZY5
    • Q9UBW0
    • Q9UJ77

    Protein attributes for ZMYM5 Gene

    Size:
    669 amino acids
    Molecular mass:
    74817 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF29022.1; Type=Frameshift; Positions=286, 322, 337; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ZMYM5 Gene

    Alternative splice isoforms for ZMYM5 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZMYM5 Gene

Proteomics data for ZMYM5 Gene at MOPED

Post-translational modifications for ZMYM5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZMYM5 Gene

No data available for DME Specific Peptides for ZMYM5 Gene

Domains for ZMYM5 Gene

Gene Families for ZMYM5 Gene

HGNC:
  • ZMYM :Zinc fingers, MYM type

Protein Domains for ZMYM5 Gene

Suggested Antigen Peptide Sequences for ZMYM5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UJ78

UniProtKB/Swiss-Prot:

ZMYM5_HUMAN :
  • Q9UJ78
Similarity:
  • Contains 4 MYM-type zinc fingers.
genes like me logo Genes that share domains with ZMYM5: view

Function for ZMYM5 Gene

Gene Ontology (GO) - Molecular Function for ZMYM5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZMYM5: view

Phenotypes for ZMYM5 Gene

GenomeRNAi human phenotypes for ZMYM5:
genes like me logo Genes that share phenotypes with ZMYM5: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZMYM5 Gene

Localization for ZMYM5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZMYM5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZMYM5 Gene COMPARTMENTS Subcellular localization image for ZMYM5 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZMYM5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZMYM5: view

Pathways for ZMYM5 Gene

SuperPathways for ZMYM5 Gene

No Data Available

Interacting Proteins for ZMYM5 Gene

Gene Ontology (GO) - Biological Process for ZMYM5 Gene

None

No data available for Pathways by source for ZMYM5 Gene

Transcripts for ZMYM5 Gene

Unigene Clusters for ZMYM5 Gene

Zinc finger, MYM-type 5:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZMYM5

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZMYM5 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c ^ 9
SP1: -
SP2: - -
SP3:
SP4: -
SP5: -
SP6:
SP7: - -

Relevant External Links for ZMYM5 Gene

GeneLoc Exon Structure for
ZMYM5
ECgene alternative splicing isoforms for
ZMYM5

Expression for ZMYM5 Gene

mRNA expression in normal human tissues for ZMYM5 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZMYM5 Gene

SOURCE GeneReport for Unigene cluster for ZMYM5 Gene Hs.530988

genes like me logo Genes that share expressions with ZMYM5: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZMYM5 Gene

Orthologs for ZMYM5 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZMYM5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZMYM5 35
  • 99.55 (n)
  • 98.95 (a)
ZMYM5 36
  • 53 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZMYM5 35
  • 85.58 (n)
  • 78.29 (a)
ZMYM5 36
  • 41 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZMYM5 35
  • 87.8 (n)
  • 80.12 (a)
mouse
(Mus musculus)
Mammalia Zmym5 35
  • 79.86 (n)
  • 68.91 (a)
Zmym5 16
Zmym5 36
  • 36 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
ManyToMany
rat
(Rattus norvegicus)
Mammalia RGD1306353 35
  • 79.98 (n)
  • 68.18 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 18 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 17 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii zmym2 36
  • 11 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta woc 36
  • 4 (a)
OneToMany
Species with no ortholog for ZMYM5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZMYM5 Gene

ENSEMBL:
Gene Tree for ZMYM5 (if available)
TreeFam:
Gene Tree for ZMYM5 (if available)

Paralogs for ZMYM5 Gene

Paralogs for ZMYM5 Gene

genes like me logo Genes that share paralogs with ZMYM5: view

Variants for ZMYM5 Gene

Sequence variations from dbSNP and Humsavar for ZMYM5 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs2016493 -- 19,837,095(+) ggcgc(A/G)atctc intron-variant
rs2340308 -- 19,840,811(+) tagct(G/T)ggact intron-variant
rs2340309 -- 19,840,820(+) ctaca(A/G)gcaca intron-variant
rs3783036 -- 19,862,366(+) AGACA(A/G)CAAAG intron-variant
rs3783037 -- 19,862,458(+) GGTGA(G/T)TCCTG utr-variant-5-prime, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZMYM5 Gene

Variant ID Type Subtype PubMed ID
nsv516945 CNV Gain+Loss 19592680
nsv899857 CNV Gain 21882294
nsv455826 CNV Loss 19166990
dgv1551n71 CNV Loss 21882294
nsv899860 CNV Loss 21882294
nsv899865 CNV Gain 21882294
dgv1553n71 CNV Loss 21882294

Relevant External Links for ZMYM5 Gene

HapMap Linkage Disequilibrium report
ZMYM5
Human Gene Mutation Database (HGMD)
ZMYM5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZMYM5 Gene

Disorders for ZMYM5 Gene

No disorders were found for ZMYM5 Gene.

No data available for UniProtKB/Swiss-Prot for ZMYM5 Gene

Publications for ZMYM5 Gene

  1. Cloning of ZNF237, a novel member of the MYM gene family that maps to human chromosome 13q11-->q12. (PMID: 10894931) Sohal J. … Cross N.C. (Cytogenet. Cell Genet. 2000) 3 4 23
  2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 3 4
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Specification of SUMO1- and SUMO2-interacting motifs. (PMID: 16524884) Hecker C.M. … Dikic I. (J. Biol. Chem. 2006) 3

Products for ZMYM5 Gene

Sources for ZMYM5 Gene

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