Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZMYM4 Gene

protein-coding   GIFtS: 50
GCID: GC01P035734

Zinc Finger, MYM-Type 4

(Previous name: zinc finger protein 262)
(Previous symbol: ZNF262)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger, MYM-Type 41 2     ZNF198L32
Zinc Finger Protein 2621 2 3     Cell Death Inhibiting RNA2
ZNF2621 2 3     Zinc Finger MYM-Type Protein 42
CDIR2     KIAA04253
MYM2     

External Ids:    HGNC: 130551   Entrez Gene: 92022   Ensembl: ENSG000001464637   OMIM: 6135685   UniProtKB: Q5VZL53   

Export aliases for ZMYM4 gene to outside databases

Previous GC identifers: GC01P035404 GC01P035507 GC01P033853


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZMYM4 Gene: 
ZMYM4 (zinc finger, MYM-type 4) is a protein-coding gene. Diseases associated with ZMYM4 include stem cell leukemia, and t-cell leukemia. GO annotations related to this gene include DNA binding and zinc ion binding. An important paralog of this gene is ENSG00000271741.

UniProtKB/Swiss-Prot: ZMYM4_HUMAN, Q5VZL5
Function: Plays a role in the regulation of cell morphology and cytoskeletal organization




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZMYM4 gene promoter:
         Pbx1a   Egr-1   FOXD3   HNF-1A   AREB6   POU2F1   HNF-1   POU2F1a   Msx-1   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ZMYM4 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZMYM4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZMYM4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32-p34   Ensembl cytogenetic band:  1p34.3   HGNC cytogenetic band: 1p34-p32

ZMYM4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZMYM4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P035734:  view genomic region     (about GC identifiers)

Start:
35,734,568 bp from pter      End:
35,887,659 bp from pter
Size:
153,092 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZMYM4_HUMAN, Q5VZL5 (See protein sequence)
Recommended Name: Zinc finger MYM-type protein 4  
Size: 1548 amino acids; 172788 Da
Miscellaneous: The 3'-UTR region of the mRNA encoding this protein contains a motif called CDIR (for cell death
inhibiting RNA) that binds HNRPD/AUF1 and HSPB1/HSP27. It is able to inhibit interferon-gamma induced apoptosis
Sequence caution: Sequence=CAI22686.1; Type=Erroneous gene model prediction; Sequence=CAI22687.1; Type=Erroneous
gene model prediction;
Secondary accessions: A0JP19 A0JP20 O43308 Q5T5E1 Q5T5E2 Q7L3Q4
Alternative splicing: 4 isoforms:  Q5VZL5-1   Q5VZL5-2   Q5VZL5-3   Q5VZL5-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZMYM4: NX_Q5VZL5

Explore proteomics data for ZMYM4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5VZL5

  • ZMYM4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZMYM4 Protein Expression
    REFSEQ proteins: NP_005086.2  
    ENSEMBL proteins: 
     ENSP00000322915   ENSP00000397524   ENSP00000400506   ENSP00000362394  

    Human Recombinant Protein Products for ZMYM4: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ZMYM4
    GenScript Custom Purified and Recombinant Proteins Services for ZMYM4
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZMYM4 


    ZMYM4 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZMYM4
    GenScript Custom Superior Antibodies Services for ZMYM4
    Novus Biologicals ZMYM4 Antibodies
    Search for Antibodies for ZMYM4 at Abcam
    Cloud-Clone Corp. Antibodies for ZMYM4 
    ThermoFisher Antibodies for ZMYM4
    LSBio Antibodies in human, mouse, rat for ZMYM4 

    Assay Products for ZMYM4: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZMYM4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZMYM4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZMYM4 
    Cloud-Clone Corp. CLIAs for ZMYM4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZMYM: Zinc fingers, MYM type

    3 InterPro protein domains:
     IPR021893 DUF3504
     IPR010507 Znf_MYM
     IPR011017 TRASH_dom

    Graphical View of Domain Structure for InterPro Entry Q5VZL5

    ProtoNet protein and cluster: Q5VZL5

    3 Blocks protein domains:
    IPB001545 Gonadotropin
    IPB010507 MYM-type zinc finger
    IPB011017 TRASH


    UniProtKB/Swiss-Prot: ZMYM4_HUMAN, Q5VZL5
    Similarity: Contains 9 MYM-type zinc fingers


    ZMYM4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZMYM4_HUMAN, Q5VZL5
    Function: Plays a role in the regulation of cell morphology and cytoskeletal organization

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding TAS10486218
    GO:0008270zinc ion binding IEA--
         
    ZMYM4 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZMYM4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZMYM4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZMYM4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZMYM4 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZMYM4
    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate ZMYM4 (see all 14):
    hsa-miR-203 hsa-miR-34c-5p hsa-miR-429 hsa-miR-449b hsa-miR-513a-5p hsa-miR-27a hsa-miR-491-3p hsa-miR-501-3p
    SwitchGear 3'UTR luciferase reporter plasmidZMYM4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZMYM4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZMYM4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZMYM4
    Sirion Biotech Customized adenovirus for overexpression of ZMYM4

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ZMYM4 (see all 7)
    OriGene ORF clones in mouse, rat for ZMYM4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZMYM4 (NM_005095)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZMYM4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMYM4

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZMYM4
    Search LifeMap BioReagents cell lines for ZMYM4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMYM4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZMYM4

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/7 Interacting proteins for ZMYM4 (Q5VZL53 ENSP000003229154) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KLHL13Q9P2N73, ENSP000002628204I2D: score=2 STRING: ENSP00000262820
    ZMYM2Q9UBW73, ENSP000003723224I2D: score=1 STRING: ENSP00000372322
    SUMO2P619563, ENSP000004059654I2D: score=1 STRING: ENSP00000405965
    ATF2P153363I2D: score=2 
    TFCP2L1Q9NZI63I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007010cytoskeleton organization IMP--
    GO:0007275multicellular organismal development TAS10486218
    GO:0022604regulation of cell morphogenesis IMP--

    ZMYM4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZMYM4

    Search CenterWatch for drugs/clinical trials and news about ZMYM4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZMYM4 gene: 
    NM_005095.2  

    Unigene Cluster for ZMYM4:

    Zinc finger, MYM-type 4
    Hs.269211  [show with all ESTs]
    Unigene Representative Sequence: NM_005095
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000314607(uc001byt.3 uc009vuu.3 uc001byu.3 uc009vuv.3)
    ENST00000441447 ENST00000457946 ENST00000482131 ENST00000470175 ENST00000492456
    ENST00000373297
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZMYM4
    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate ZMYM4 (see all 14):
    hsa-miR-203 hsa-miR-34c-5p hsa-miR-429 hsa-miR-449b hsa-miR-513a-5p hsa-miR-27a hsa-miR-491-3p hsa-miR-501-3p
    SwitchGear 3'UTR luciferase reporter plasmidZMYM4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZMYM4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZMYM4
    Clone
    Products:
         
    OriGene clones in human, mouse for ZMYM4 (see all 7)
    OriGene ORF clones in mouse, rat for ZMYM4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZMYM4 (NM_005095)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZMYM4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMYM4
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ZMYM4
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZMYM4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZMYM4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZMYM4

    Additional mRNA sequence: 

    AB007885.1 AK308320.1 AK309705.1 BC012093.1 BC127113.1 BC127114.1 BX647376.1 BX648067.1 
    CR936741.1 

    10 DOTS entries:

    DT.101973250  DT.100780312  DT.316601  DT.100642347  DT.100675914  DT.100756362  DT.75190873  DT.75200200 
    DT.91948969  DT.100688598 

    24/227 AceView cDNA sequences (see all 227):

    CB269523 NM_005095 BI494520 BC012093 AA483696 AA953350 BM789050 BQ101158 
    AI669561 BE349185 CK823143 AA897167 AI341198 BF516492 AI923936 BM504601 
    AA331947 BE858967 BM967368 AI221823 AA251887 AI277244 AA564814 BM504603 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ZMYM4 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^
    SP1:                                                                                -                                                                           
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:              -                                                                                                                                             

    ExUns: 21 ^ 22 ^ 23 ^ 24 ^ 25a · 25b ^ 26 ^ 27a · 27b ^ 28a · 28b ^ 29 ^ 30a · 30b ^ 31
    SP1:                          -                             -                                 
    SP2:                                                                                          
    SP3:                                                                                          
    SP4:                                                                                          
    SP5:                                                                                          


    ECgene alternative splicing isoforms for ZMYM4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZMYM4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZMYM4 Expression
    About this image


    See ZMYM4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZMYM4

    SOURCE GeneReport for Unigene cluster: Hs.269211

    UniProtKB/Swiss-Prot: ZMYM4_HUMAN, Q5VZL5
    Tissue specificity: Expressed at higher level in heart, skeletal muscle, kidney and liver

        SABiosciences Custom PCR Arrays for ZMYM4
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ZMYM4
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZMYM4
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZMYM4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZMYM4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMYM4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ZMYM4 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zmym41 , 5 zinc finger, MYM-type 41, 5 91.76(n)1
    94.5(a)1
      4 (61.05 cM)5
    677851  NM_001114399.11  NP_001107871.11 
     1268619395 
    chicken
    (Gallus gallus)
    Aves ZMYM41 zinc finger, MYM-type 4 80.2(n)
    84.01(a)
      419635  XM_417783.3  XP_417783.3 
    African clawed frog
    (Xenopus laevis)
    Amphibia BU911075.12   -- 77.07(n)    BU911075.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zmym41 zinc finger, MYM-type 4 55.82(n)
    51.36(a)
      327248  NM_001044312.1  NP_001037777.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta woc6
    without children
    19(a)
    1 → many
    3R(23082315-23089758)


    ENSEMBL Gene Tree for ZMYM4 (if available)
    TreeFam Gene Tree for ZMYM4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZMYM4 gene
    ENSG000002717412  ZMYM12  ZMYM52  ZMYM32  ZMYM62  ZMYM22  QRICH12  
    4 SIMAP similar genes for ZMYM4 using alignment to 2 protein entries:     ZMYM4_HUMAN (see all proteins):
    ZMYM1    ZMYM6    ZMYM3    ZMYM2

    ZMYM4 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for ZMYM4
    PGOHUM00000238804 PGOHUM00000237323


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2988 SNPs in ZMYM4 are shown (see all 2988)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0356724
    A colorectal cancer sample4--see VAR_0356722 R W mis40--------
    rs1885858101,2
    --35732609(+) AGTTAG/TACTAA 1 -- us2k10--------
    rs1149805971,2
    F--35732617(+) TAAACT/CAATAA 1 -- us2k11Minor allele frequency- C:0.07WA 118
    rs1157754391,2
    F--35732619(+) AACTAA/GTAAGT 1 -- us2k11Minor allele frequency- G:0.07WA 118
    rs728952911,2
    C--35732742(+) ACTCCC/TAACTT 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1469070691,2
    --35732895(+) TGGACA/GTGGAA 1 -- us2k10--------
    rs1815279111,2
    --35732961(+) TCTTTC/TTTCTC 1 -- us2k10--------
    rs1512393221,2
    C--35733004(+) AAAGGC/TATAAG 1 -- us2k10--------
    rs801182501,2
    F--35733196(+) GAAATA/GACCTT 1 -- us2k10--------
    rs1870580391,2
    --35733272(+) ACTTAA/TTTTTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZMYM4 (35734568 - 35887659 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for ZMYM4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv870976CNV Loss21882294
    esv32554CNV Loss17666407
    nsv818134CNV Loss17921354
    nsv508149CNV Loss20534489
    nsv822298CNV Loss20364138
    nsv870757CNV Gain21882294
    nsv822287CNV Gain20364138
    esv8737CNV Gain19470904

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ZMYM4
    DNA2.0 Custom Variant and Variant Library Synthesis for ZMYM4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613568    OMIM disorders: --

    4 diseases for ZMYM4:    About MalaCards
    stem cell leukemia    t-cell leukemia    mental retardation    leukemia

    1 disease from the University of Copenhagen DISEASES database for ZMYM4:
    non-specific X-linked mental retardation

    ZMYM4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZMYM4

    Export disorders for ZMYM4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZMYM4 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with ZMYM4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Assignment of ZNF262 to human chromosome band 1p34-->p32 by in situ hybridization. (PubMed id 10449923)1, 2, 3 Sohal J.... Cross N.C.P. (1999)
    2. Cell death inhibiting RNA (CDIR) derived from a 3'-untranslated region binds AUF1 and heat shock protein 27. (PubMed id 12356764)1, 2 Shchors K.... Deiss L.P. (2002)
    3. Cloning and mapping of members of the MYM family. (PubMed id 10486218)1, 2 Smedley D.... Shipley J. (1999)
    4. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)1, 2 Ishikawa K....Ohara O. (1997)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    7. Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. (PubMed id 21834987)2 Bai S.W.... Ridley A.J. (2011)
    8. Interaction proteomics analysis of polycomb proteins defines distinct PRC1 Complexes in mammalian cells. (PubMed id 21282530)1 Vandamme J.... Angrand P.O. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9202 HGNC: 13055 AceView: ZNF262 Ensembl:ENSG00000146463 euGenes: HUgn9202
    ECgene: ZMYM4 H-InvDB: ZMYM4

    (According to HUGE)
    About This Section
    HUGE: KIAA0425

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZMYM4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZMYM4 gene:
    Search GeneIP for patents involving ZMYM4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZMYM4  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ZMYM4  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZMYM4   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ZMYM4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZMYM4   OriGene Custom Protein Services for ZMYM4  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZMYM4
     QIAGEN SeqTarget long-range PCR primers for resequencing ZMYM4
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZMYM4
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZMYM4
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZMYM4
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZMYM4
     GenScript Custom Purified and Recombinant Proteins Services for ZMYM4 GenScript cDNA clones with any tag delivered in your preferred vector for ZMYM4
     GenScript Custom Assay Services for ZMYM4 GenScript Custom Superior Antibodies Services for ZMYM4
     GenScript Custom overexpressing Cell Line Services for ZMYM4 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ZMYM4 promoter
     Search Chromatin IP Primers for ZMYM4
     RT2 qPCR Primer Assay in human, mouse / rat ZMYM4
     Search GNC Networks for ZMYM4
     SABiosciences Custom PCR Arrays for ZMYM4
     Search Tocris compounds for ZMYM4
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ZMYM4 antibodies
     Search for Antibodies for ZMYM4 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ZMYM4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ZMYM4
     Antibodies for ZMYM4
     ELISAs for ZMYM4
     CLIAs for ZMYM4
     Search LifeMap BioReagents cell lines for ZMYM4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMYM4
     SwitchGear 3'UTR luciferase reporter plasmids for ZMYM4
     SwitchGear Promoter luciferase reporter plasmids for ZMYM4
     ThermoFisher Antibodies for ZMYM4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMYM4
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ZMYM4
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZMYM4
    Customized:
     lentivirus for stable overexpression
     lentivirus expression plasmids for stable overexpression
     adenovirus for overexpression of ZMYM4
     LSBio Antibodies in human, mouse, rat for ZMYM4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZMYM4 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4