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Aliases for ZMYM1 Gene

Aliases for ZMYM1 Gene

  • Zinc Finger, MYM-Type 1 2 3
  • Zinc Finger, MYM Domain Containing 1 2 3
  • MYM 3

External Ids for ZMYM1 Gene

Previous GeneCards Identifiers for ZMYM1 Gene

  • GC01P034972
  • GC01P035214
  • GC01P035317
  • GC01P035526
  • GC01P033662

Summaries for ZMYM1 Gene

GeneCards Summary for ZMYM1 Gene

ZMYM1 (Zinc Finger, MYM-Type 1) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and protein dimerization activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZMYM1 Gene

Genomics for ZMYM1 Gene

Regulatory Elements for ZMYM1 Gene

Genomic Location for ZMYM1 Gene

Chromosome:
1
Start:
35,059,786 bp from pter
End:
35,115,859 bp from pter
Size:
56,074 bases
Orientation:
Plus strand

Genomic View for ZMYM1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZMYM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZMYM1 Gene

Proteins for ZMYM1 Gene

  • Protein details for ZMYM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5SVZ6-ZMYM1_HUMAN
    Recommended name:
    Zinc finger MYM-type protein 1
    Protein Accession:
    Q5SVZ6
    Secondary Accessions:
    • D3DPR7
    • Q7Z3Q4

    Protein attributes for ZMYM1 Gene

    Size:
    1142 amino acids
    Molecular mass:
    128717 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZMYM1 Gene

Proteomics data for ZMYM1 Gene at MOPED

Post-translational modifications for ZMYM1 Gene

  • Ubiquitination at Lys 106
  • Modification sites at PhosphoSitePlus

Other Protein References for ZMYM1 Gene

No data available for DME Specific Peptides for ZMYM1 Gene

Domains & Families for ZMYM1 Gene

Gene Families for ZMYM1 Gene

Protein Domains for ZMYM1 Gene

Graphical View of Domain Structure for InterPro Entry

Q5SVZ6

UniProtKB/Swiss-Prot:

ZMYM1_HUMAN :
  • Contains 4 MYM-type zinc fingers.
Similarity:
  • Contains 4 MYM-type zinc fingers.
  • Contains 1 TTF-type zinc finger.
genes like me logo Genes that share domains with ZMYM1: view

Function for ZMYM1 Gene

Gene Ontology (GO) - Molecular Function for ZMYM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0008270 zinc ion binding IEA --
GO:0046983 protein dimerization activity IEA --
genes like me logo Genes that share ontologies with ZMYM1: view
genes like me logo Genes that share phenotypes with ZMYM1: view

Animal Model Products

miRNA for ZMYM1 Gene

miRTarBase miRNAs that target ZMYM1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZMYM1 Gene

Localization for ZMYM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZMYM1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZMYM1 Gene COMPARTMENTS Subcellular localization image for ZMYM1 gene
Compartment Confidence
nucleus 3
cytoskeleton 2

Gene Ontology (GO) - Cellular Components for ZMYM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZMYM1: view

Pathways & Interactions for ZMYM1 Gene

SuperPathways for ZMYM1 Gene

No Data Available

Interacting Proteins for ZMYM1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000352920%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000405965%0d%0a
Selected Interacting proteins: ENSP00000352920 for ZMYM1 Gene via STRING

Gene Ontology (GO) - Biological Process for ZMYM1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZMYM1 Gene

Drugs & Compounds for ZMYM1 Gene

No Compound Related Data Available

Transcripts for ZMYM1 Gene

Unigene Clusters for ZMYM1 Gene

Zinc finger, MYM-type 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZMYM1 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b
SP1: - -
SP2: - - -
SP3: - - - - -
SP4: - - - -
SP5: - - -
SP6:

Relevant External Links for ZMYM1 Gene

GeneLoc Exon Structure for
ZMYM1
ECgene alternative splicing isoforms for
ZMYM1

Expression for ZMYM1 Gene

mRNA expression in normal human tissues for ZMYM1 Gene

Protein differential expression in normal tissues from HIPED for ZMYM1 Gene

This gene is overexpressed in Fetal Liver (68.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZMYM1 Gene



SOURCE GeneReport for Unigene cluster for ZMYM1 Gene Hs.471243

genes like me logo Genes that share expression patterns with ZMYM1: view

Protein tissue co-expression partners for ZMYM1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZMYM1 Gene

Orthologs for ZMYM1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ZMYM1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZMYM1 35
  • 87.02 (n)
  • 80.27 (a)
ZMYM1 36
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZMYM1 35
  • 87.43 (n)
  • 82.36 (a)
ZMYM1 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zmym1 35
  • 73.19 (n)
  • 63.2 (a)
Zmym1 16
Zmym1 36
  • 64 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZMYM1 35
  • 99.65 (n)
  • 99.56 (a)
ZMYM1 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zmym1 35
  • 73.41 (n)
  • 63.17 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 20 (a)
OneToMany
-- 36
  • 24 (a)
OneToMany
-- 36
  • 22 (a)
OneToMany
-- 36
  • 22 (a)
OneToMany
-- 36
  • 23 (a)
OneToMany
-- 36
  • 21 (a)
OneToMany
-- 36
  • 22 (a)
OneToMany
-- 36
  • 23 (a)
OneToMany
-- 36
  • 21 (a)
OneToMany
-- 36
  • 19 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii LOC101886631 35
  • 45.13 (n)
  • 29.84 (a)
ZMYM1 36
  • 19 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G06541 35
  • 46.31 (n)
  • 31.14 (a)
rice
(Oryza sativa)
Liliopsida Os01g0293600 35
  • 44.71 (n)
  • 29.21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 24 (a)
OneToOne
Species with no ortholog for ZMYM1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZMYM1 Gene

ENSEMBL:
Gene Tree for ZMYM1 (if available)
TreeFam:
Gene Tree for ZMYM1 (if available)

Paralogs for ZMYM1 Gene

(2) SIMAP similar genes for ZMYM1 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZMYM1 Gene

genes like me logo Genes that share paralogs with ZMYM1: view

No data available for Paralogs for ZMYM1 Gene

Variants for ZMYM1 Gene

Sequence variations from dbSNP and Humsavar for ZMYM1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1134120 -- 35,116,049(+) AACAT(A/G)GTAAG downstream-variant-500B
rs1809853 -- 35,096,099(-) CTGAC(C/T)TCATG intron-variant
rs2101973 -- 35,095,909(-) ACTAA(C/T)TTAAA intron-variant
rs2935950 -- 35,091,622(-) TCTGC(G/T)CCCAG intron-variant, upstream-variant-2KB
rs2935951 -- 35,089,083(-) tgaaa(C/T)ccctg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZMYM1 Gene

Variant ID Type Subtype PubMed ID
nsv870757 CNV Gain 21882294
nsv422 CNV Insertion 18451855

Variation tolerance for ZMYM1 Gene

Residual Variation Intolerance Score: 21.25% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.22; 69.95% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZMYM1 Gene

HapMap Linkage Disequilibrium report
ZMYM1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZMYM1 Gene

Disorders for ZMYM1 Gene

Relevant External Links for ZMYM1

Genetic Association Database (GAD)
ZMYM1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZMYM1
genes like me logo Genes that share disorders with ZMYM1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZMYM1 Gene

Publications for ZMYM1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. (PMID: 25852190) So J. … Colwill K. (Sci Signal 2015) 67
  4. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PMID: 20360068) Hutchins J.R. … Peters J.M. (Science 2010) 67
  5. Genome-wide association with diabetes-related traits in the Framingham Heart Study. (PMID: 17903298) Meigs J.B. … Dupuis J. (BMC Med. Genet. 2007) 67

Products for ZMYM1 Gene

Sources for ZMYM1 Gene

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