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ZMIZ2 Gene

protein-coding   GIFtS: 55
GCID: GC07P044756

Zinc Finger, MIZ-Type Containing 2

  See ZMIZ2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, MIZ-Type Containing 21 2     NET272
ZIMP72 3 5     TRAFIP202
PIAS-Like Protein Zimp72 3     hZIMP72
KIAA18863 5     Zinc Finger MIZ Domain-Containing Protein 22

External Ids:    HGNC: 222291   Entrez Gene: 836372   Ensembl: ENSG000001225157   OMIM: 6111965   UniProtKB: Q8NF643   

Export aliases for ZMIZ2 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZMIZ2 Gene:
ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with
nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated
transcription (Huang et al., 2005 (PubMed 16051670)).(supplied by OMIM, May 2010)

GeneCards Summary for ZMIZ2 Gene:
ZMIZ2 (zinc finger, MIZ-type containing 2) is a protein-coding gene. Diseases associated with ZMIZ2 include blepharitis. GO annotations related to this gene include ligand-dependent nuclear receptor transcription coactivator activity. An important paralog of this gene is PIAS3.

UniProtKB/Swiss-Prot: ZMIZ2_HUMAN, Q8NF64
Function: Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors

Gene Wiki entry for ZMIZ2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007819.18  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZMIZ2 gene promoter:
         Pax-5   Lmo2   CUTL1   LUN-1   LCR-F1   GATA-1   PPAR-alpha   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 6): ZMIZ2 promoter sequence
   Search Chromatin IP Primers for ZMIZ2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZMIZ2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p13   Ensembl cytogenetic band:  7p13   HGNC cytogenetic band: 7p13

ZMIZ2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZMIZ2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P044756:  view genomic region     (about GC identifiers)

Start:
44,788,180 bp from pter      End:
44,809,480 bp from pter
Size:
21,301 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 44,828,066-44,849,014     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ZMIZ2_HUMAN, Q8NF64 (See protein sequence)
Recommended Name: Zinc finger MIZ domain-containing protein 2  
Size: 920 amino acids; 96537 Da
Subunit: Interacts with AR, SMARCA4/BRG1 and SMARCE1/BAF57. Interaction with either SMARCA4 and SMARCE1 enhances
AR-mediated transcription
Sequence caution: Sequence=AAH21924.1; Type=Erroneous initiation; Sequence=BAC03396.1; Type=Erroneous initiation;
Sequence=CAB66507.1; Type=Erroneous initiation;
Secondary accessions: A4D2K7 D3DVL1 O94790 Q0VGB4 Q659A8 Q6JKL5 Q8WTX8 Q96Q01 Q9BQH7
Alternative splicing: 3 isoforms:  Q8NF64-1   Q8NF64-2   Q8NF64-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZMIZ2: NX_Q8NF64

Explore proteomics data for ZMIZ2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZMIZ2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_113637.3  NP_777589.2  

    ENSEMBL proteins: 
     ENSP00000409648   ENSP00000415501   ENSP00000311778   ENSP00000406820   ENSP00000396601  
     ENSP00000265346   ENSP00000414723  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZMIZ: Zinc fingers, MIZ-type

    1 InterPro protein domain:
     IPR004181 Znf_MIZ

    Graphical View of Domain Structure for InterPro Entry Q8NF64

    ProtoNet protein and cluster: Q8NF64

    1 Blocks protein domain: IPB004181 Zn-finger

    UniProtKB/Swiss-Prot: ZMIZ2_HUMAN, Q8NF64
    Domain: The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity. This
    activity is inhibited by the N-terminus in the full-length protein
    Similarity: Contains 1 SP-RING-type zinc finger


    Find genes that share domains with ZMIZ2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZMIZ2_HUMAN, Q8NF64
    Function: Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16051670
    GO:0008270zinc ion binding IEA--
    GO:0030374ligand-dependent nuclear receptor transcription coactivator activity IDA16051670
         
    Find genes that share ontologies with ZMIZ2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ZMIZ2:
     Increased S DNA content 

         1 MGI phenotypic allele for Zmiz2 (no phenotypes)

    Find genes that share phenotypes with ZMIZ2           About GenesLikeMe

    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidZMIZ2 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZMIZ2_HUMAN, Q8NF64: Nucleus. Note=Detected at replication foci throughout S phase
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion4
    plasma membrane2
    cytosol1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005739mitochondrion IDA--
    GO:0043596nuclear replication fork IDA16051670

    Find genes that share ontologies with ZMIZ2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZMIZ2 About    
    See pathways by source

    SuperPathContained pathways About
    1Regulation of Androgen receptor activity
    Regulation of Androgen receptor activity


    1 BioSystems Pathway for ZMIZ2
        Regulation of Androgen receptor activity


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZMIZ2
    Interactions:

        Search GeneGlobe Interaction Network for ZMIZ2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ZMIZ2 (Q8NF642, 3 ENSP000003117784) via UniProtKB, MINT, STRING, and/or I2D (see all 54)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PIN1Q135262, 3, ENSP000002479704MINT-66724 I2D: score=5 STRING: ENSP00000247970
    SALL2Q9Y4673, ENSP000003335374I2D: score=3 STRING: ENSP00000333537
    ARP102753, ENSP000003638224I2D: score=1 STRING: ENSP00000363822
    PIAS1O759253, ENSP000002496364I2D: score=1 STRING: ENSP00000249636
    PIAS4Q8N2W93, ENSP000002629714I2D: score=1 STRING: ENSP00000262971
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0045944positive regulation of transcription from RNA polymerase II promoter IDA16051670

    Find genes that share ontologies with ZMIZ2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZMIZ2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZMIZ2 gene (2 alternative transcripts): 
    NM_031449.3  NM_174929.2  

    Unigene Clusters for ZMIZ2:

    Zinc finger, MIZ-type containing 2
    Hs.77978  [show with all ESTs], Hs.600681  [show with all ESTs]
    Unigene Representative Sequences: NM_031449, BC008049
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000413916 ENST00000457123 ENST00000309315(uc003tlr.3) ENST00000416856
    ENST00000492001 ENST00000433667 ENST00000265346 ENST00000478045 ENST00000463056
    ENST00000480964 ENST00000492558 ENST00000463931 ENST00000482322 ENST00000441627(uc003tlq.3 uc003tls.3 uc003tlt.3 uc010kyj.3 uc003tlu.3)

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    hsa-miR-3173-3p hsa-miR-185* hsa-miR-1324 hsa-miR-4255 hsa-miR-3647-3p hsa-miR-218 hsa-miR-3160-3p hsa-miR-890
    SwitchGear 3'UTR luciferase reporter plasmidZMIZ2 3' UTR sequence
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      QuantiFast Probe-based Assays in human, mouse, rat ZMIZ2

    Additional mRNA sequence: 

    AK097263.1 BC008049.2 

    17 DOTS entries:

    DT.97797119  DT.100789872  DT.100666562  DT.91754218  DT.100030508  DT.101961219  DT.91729700  DT.100789869 
    DT.91748350  DT.75101580  DT.438495  DT.91754215  DT.97798992  DT.100789873  DT.91754217  DT.91955340 
    DT.121080183 

    Selected AceView cDNA sequences (see all 195):

    AY426594 BF589720 BQ272250 AB067473 AW444969 AI914892 BE220886 AK090415 
    AL136572 BQ081875 AK090841 AW081833 AL831933 BF968199 BM680197 AI572061 
    BF114989 AA077801 AI870972 AI559163 AI494261 AK057378 BC021924 AI275786 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZMIZ2 (see all 12)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a ·
    SP1:                                                                    -     -           -                                               -                     
    SP2:                                      -                             -     -     -     -                                               -                     
    SP3:                                                                                                                                      -                     
    SP4:                    -     -                                                                                                                                 
    SP5:                                                                                                                                                            

    ExUns: 16b ^ 17a · 17b ^ 18 ^ 19 ^ 20a · 20b · 20c ^ 21a · 21b · 21c · 21d ^ 22a · 22b
    SP1:        -     -                                                                     
    SP2:        -     -                                                                     
    SP3:        -     -                                                                     
    SP4:                                                                                    
    SP5:                                                                                    


    ECgene alternative splicing isoforms for ZMIZ2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZMIZ2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCACGTGCCT
    ZMIZ2 Expression
    About this image

    ZMIZ2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZMIZ2 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.77978 Hs.600681

    UniProtKB/Swiss-Prot: ZMIZ2_HUMAN, Q8NF64
    Tissue specificity: Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and
    ovary

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMIZ2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ZMIZ2 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zmiz21 , 5 zinc finger, MIZ-type containing 21, 5 88.15(n)1
    90.87(a)1
      11 (3.95 cM)5
    529151  NM_028601.21  NP_082877.21 
     63890745 
    lizard
    (Anolis carolinensis)
    Reptilia ZMIZ26
    zinc finger, MIZ-type containing 2
    77(a)
    1 ↔ 1
    GL343238.1(687291-784896)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.243382 Xenopus laevis transcribed sequence with weak similarity more 78.47(n)    BX847575.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zmiz21 zinc finger, MIZ-type containing 2 71.6(n)
    72.95(a)
      100333571  XM_005155481.1  XP_005155538.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta tna6
    tonalli
    28(a)
    1 → many
    3L(10850989-10869596)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NFI16
    SIZ16
    SUMO E3 ligase, catalyzes the covalent attachment ...
    SUMO/Smt3 ligase that promotes the attachment of s...
    15(a)
    14(a)
    many ↔ many
    many ↔ many
    XV(628360-630540) YOR156C
    IV(1289406-1292120) YDR409W


    ENSEMBL Gene Tree for ZMIZ2 (if available)
    TreeFam Gene Tree for ZMIZ2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZMIZ2 gene
    PIAS32  PIAS12  PIAS22  ZMIZ12  PIAS42  
    4 SIMAP similar genes for ZMIZ2 using alignment to 5 protein entries:     ZMIZ2_HUMAN (see all proteins):
    TRAFIP20    TRAFIP10    FLJ00092    ZMIZ1

    Find genes that share paralogs with ZMIZ2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZMIZ2 (see all 506)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs725953531,2
    C--44786591(+) AGGGGC/ACTTAT 1 -- us2k13Minor allele frequency- A:0.20NA EA 242
    rs1413910331,2
    --44786655(+) TTGTAC/TAGCAG 1 -- us2k10--------
    rs1474637651,2
    --44786724(+) AGAGGC/TGGCCT 1 -- us2k10--------
    rs1846699761,2
    --44786725(+) GAGGCA/GGCCTT 1 -- us2k10--------
    rs731094621,2
    C,F--44786840(+) GCCATA/GAGAAA 1 -- us2k13Minor allele frequency- G:0.05NA EA 242
    rs1894940041,2
    --44786848(+) AAAGAA/CGGGGC 1 -- us2k10--------
    rs69426531,2
    C,F--44786859(+) tgggcG/Accgtg 1 -- us2k12Minor allele frequency- A:0.10WA 120
    rs132323031,2
    C,F--44786871(+) ctcacG/Acctgt 1 -- us2k13Minor allele frequency- A:0.33NA 6
    rs1399414381,2
    --44786875(+) CGCCTA/GTAATC 1 -- us2k10--------
    rs1454854221,2
    C--44786927(+) GGAGAC/TCGATT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZMIZ2 (44788180 - 44809480 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ZMIZ2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv5722CNV Insertion18451855
    nsv887999CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing ZMIZ2
    DNA2.0 Custom Variant and Variant Library Synthesis for ZMIZ2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611196    OMIM disorders: --

    1 disease for ZMIZ2:    
    About MalaCards
    blepharitis

    1 disease from the University of Copenhagen DISEASES database for ZMIZ2:
    Blepharitis

    Find genes that share disorders with ZMIZ2           About GenesLikeMe


    Export disorders for ZMIZ2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZMIZ2 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with ZMIZ2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. hZimp7, a novel PIAS-like protein, enhances androgen receptor- mediated transcription and interacts with SWI/SNF-like BAF complexes. (PubMed id 16051670)1, 2 Huang C.-Y....Sun Z. (Mol. Endocrinol. 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    5. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (Nature 2003)
    6. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2 Nagase T.... Ohara O. (DNA Res. 2001)
    7. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    8. Selection system for genes encoding nuclear-targeted proteins. (PubMed id 9853615)1, 2 Ueki N.... Muramatsu M.-A. (Nat. Biotechnol. 1998)
    9. Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase. (PubMed id 23277564)1 Delker R.K....Papavasiliou F.N. (Proc. Natl. Acad. Sci. U.S.A. 2013)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83637 HGNC: 22229 AceView: DKFZp761I2123 Ensembl:ENSG00000122515 euGenes: HUgn83637
    ECgene: ZMIZ2 H-InvDB: ZMIZ2

    (According to HUGE)
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    HUGE: KIAA1886

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZMIZ2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZMIZ2 gene:
    Search GeneIP for patents involving ZMIZ2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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