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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZMIZ1 Gene

protein-coding   GIFtS: 53
GCID: GC10P080828

zinc finger, MIZ-type containing 1

(Previous name: retinoic acid induced 17 )
(Previous symbol: RAI17)
 Explore 12 diseases affiliated with
ZMIZ1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ZMIZ1    

Aliases
for ZMIZ1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Zinc Finger, MIZ-Type Containing 11 2     FLJ135411
RAI171 2 3 5     Zimp101
KIAA12241 3 5     TRAFIP102
ZIMP102 3 5     FLJ00092 Protein2
MIZ1 2     Zinc Finger MIZ Domain-Containing Protein 12
RP11-519K18.11 2     Zinc Finger-Containing, Miz1, PIAS-Like Protein On Chromosome 102
HZIMP101     PIAS-Like Protein Zimp103
Retinoic Acid Induced 171 2     Retinoic Acid-Induced Protein 173

External Ids:    HGNC: 164931   Entrez Gene: 571782   Ensembl: ENSG000001081757   OMIM: 6071595   UniProtKB: Q9ULJ63   
ORGUL members:         
NONCODE:n342605    

Export aliases for ZMIZ1 gene to outside databases

Previous GC identifers: GC10P080498 GC10P080631 GC10P074825


Summaries
for ZMIZ1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ZMIZ1:
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein
regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The
encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the
protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. (provided by
RefSeq, Mar 2010)

UniProtKB/Swiss-Prot: ZMIZ1_HUMAN, Q9ULJ6
Function: Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR
activity is dependent upon sumoylation

Gene Wiki entry for ZMIZ1


Genomic Views
for ZMIZ1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZMIZ1 gene promoter:
         Pax-5   MyoD   MIF-1   RORalpha2   MEF-2A   PPAR-gamma1   POU2F1   POU2F1a   PPAR-gamma2   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZMIZ1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZMIZ1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZMIZ1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.3   Ensembl cytogenetic band:  10q22.3   HGNC cytogenetic band: 10q22.3

ZMIZ1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZMIZ1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P080828:  view genomic region     (about GC identifiers)

Start:
 80,828,792 bp from pter      End:
 81,076,285 bp from pter
Size:
 247,494 bases      Orientation:
 plus strand

Proteins
for ZMIZ1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ZMIZ1_HUMAN, Q9ULJ6 (See protein sequence)
Recommended Name: Zinc finger MIZ domain-containing protein 1  
Size: 1067 amino acids; 115483 Da
Subunit: Interacts with AR, but not with ESR1, NR3C1, PGR, THRB nor VDR
Subcellular location: Nucleus speckle. Cytoplasm
Secondary accessions: Q5JSH9 Q7Z7E6
Alternative splicing: 2 isoforms:  Q9ULJ6-1   Q9ULJ6-2   (Incomplete sequence. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZMIZ1: NX_Q9ULJ6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9ULJ6

    • ZMIZ1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_065071.1  
    ENSEMBL proteins: 
     ENSP00000334474   ENSP00000401558  

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    Uscn Proteins for ZMIZ1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0016607nuclear speck IEA--


    ZMIZ1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ZMIZ1

    Protein Domains /
    Families
    for ZMIZ1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ZMIZ1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR004181 Znf_MIZ
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q9ULJ6

    ProtoNet protein and cluster: Q9ULJ6

    UniProtKB/Swiss-Prot: ZMIZ1_HUMAN, Q9ULJ6
    Domain: The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity. This activity is
    inhibited by the N-terminus in the full-length protein
    Similarity: Contains 1 SP-RING-type zinc finger


    Function
    for ZMIZ1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ZMIZ1_HUMAN, Q9ULJ6
    Function: Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR
    activity is dependent upon sumoylation

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    hsa-miR-548j hsa-miR-300 hsa-miR-605 hsa-miR-138-2* hsa-miR-759 hsa-miR-3162-5p hsa-miR-409-5p hsa-miR-3622b-3p
    SwitchGear 3'UTR luciferase reporter plasmid: ZMIZ1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--


    ZMIZ1 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for ZMIZ1:
     Decreased viability with pacli  Increased gamma-H2AX phosphory 

    Animal Models:
         Mouse knock-out Zmiz1tm1Zsu for ZMIZ1
         8 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Zmiz1):
     cardiovascular system  cellular  craniofacial  embryogenesis  growth/size 
     hematopoietic system  integument  mortality/aging 

    ZMIZ1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for ZMIZ1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Integrated Breast Cancer Pathway
    		Integrated Breast Cancer Pathway1.00
    2Coregulation of Androgen receptor activity
    		Coregulation of Androgen receptor activity1.00
    3Androgen receptor signaling pathway
    		Androgen receptor signaling pathway1.00


    3 BioSystems Pathways for ZMIZ1 
        Integrated Breast Cancer Pathway
    Androgen receptor signaling pathway
    Coregulation of Androgen receptor activity


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZMIZ1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/9 Interacting proteins for ZMIZ1 (Q9ULJ62, 3 ENSP000003344744) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARP102753, ENSP000003638224I2D: score=2 STRING: ENSP00000363822
    CACHD1Q5VU973, ENSP000002900394I2D: score=2 STRING: ENSP00000290039
    TP53P046373, ENSP000002693054I2D: score=1 STRING: ENSP00000269305
    PIAS3Q9Y6X23, ENSP000003767654I2D: score=1 STRING: ENSP00000376765
    CNTNAP2Q9UHC63, ENSP000003547784I2D: score=2 STRING: ENSP00000354778
    About this table

    Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001570vasculogenesis IEA--
    GO:0001701in utero embryonic development IEA--
    GO:0003007heart morphogenesis IEA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----


    ZMIZ1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ZMIZ1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZMIZ1
    Search CenterWatch for drugs/clinical trials and news about ZMIZ1 

    Transcripts
    for ZMIZ1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ZMIZ1 gene: 
    NM_020338.3  

    Unigene Cluster for ZMIZ1:

    Zinc finger, MIZ-type containing 1
    Hs.193118  [show with all ESTs]
    Unigene Representative Sequence: NM_020338
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000334512(uc001kaf.2 uc001kae.3 uc001kag.2 uc010qlq.1)
    ENST00000472035 ENST00000478357(uc001kah.1) ENST00000446377

    miRNA
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    hsa-miR-548j hsa-miR-300 hsa-miR-605 hsa-miR-138-2* hsa-miR-759 hsa-miR-3162-5p hsa-miR-409-5p hsa-miR-3622b-3p
    SwitchGear 3'UTR luciferase reporter plasmid: ZMIZ1 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: ZMIZ1
    OriGene siRNA: ZMIZ1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZMIZ1
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZMIZ1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZMIZ1

    Additional cDNA sequence: 

    AB033050.2 AF070622.1 AF357909.1 AK023603.1 AK024490.1 AK025812.1 AL049432.1 AY235683.1 
    BC007288.1 BC025342.1 BC035890.1 BC049845.1 BC117687.2 

    16 DOTS entries:

    DT.318444  DT.100786689  DT.99935422  DT.97864176  DT.100786692  DT.75189419  DT.97792558  DT.100786696 
    DT.121274709  DT.121274846  DT.121274884  DT.430051  DT.86846869  DT.95204015  DT.91804110  DT.95111872 

    24/272 AceView cDNA sequences (see all 272):

    AI870797 BQ631840 AW129048 AI139371 AW504502 BU633603 AJ346314 BG059981 
    BU787553 AA977527 BQ214716 AA306791 AU157689 NM_020338 CA446702 AA443116 
    AA954680 AA610084 AI125915 AI160049 AI937270 AA234094 T52132 AW025448 

    GeneLoc Exon Structure


    Expression
    for ZMIZ1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZMIZ1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See ZMIZ1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZMIZ1

    SOURCE GeneReport for Unigene cluster: Hs.193118

    UniProtKB/Swiss-Prot: ZMIZ1_HUMAN, Q9ULJ6
    Tissue specificity: Expressed most abundantly in ovary and, at lower levels, in prostate, spleen and testis. Weak
    expression, if any, in thymus, small intestine, colon and peripheral blood leukocytes

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    In Situ
    Assay Products:     
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    Orthologs
    for ZMIZ1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ZMIZ1 gene from 7/25 species (see all 25)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves ZMIZ11 zinc finger, MIZ-type containing 1 81.24(n)
    94.5(a)    		   423724  XM_003641477.1  XP_003641525.1 
    lizard
    (Anolis carolinensis)    		 Reptilia ZMIZ16
    ZMIZ16
    		 --
    		 89(a)
    16(a)
    		 1 ↔ 1
    possible ortholog
    		 GL343468.1(489110-568740)
    GL343468.1(382509-395641)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.74462 Transcribed sequence with weak similarity to protein more 82.27(n)    AL846714.2 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufb80e102 wufb80e10 81.22(n)   323065  57046570 
    fruit fly
    (Drosophila melanogaster)    		 Insecta tna1 tonalli 52.83(n)
    45.38(a)    		   39217  NM_140155.3  NP_648412.2 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons SIZ16
    EMB30016
    (see all 3)    		 zinc ion binding protein
    (see all 3)    		 9(a)
    9(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 5(24294890-24301147)
    1(2856227-2861170)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 4)    		 zinc finger protein, putative, expressed
    (see all 4)    		 9(a)
    8(a)
    (see all 4)    		 many ↔ many
    many ↔ many
    (see all 4)    		 3(29119839-29128018)
    6(3249463-3260365)


    ENSEMBL Gene Tree for ZMIZ1 (if available)
    TreeFam Gene Tree for ZMIZ1 (if available) 

    Paralogs
    for ZMIZ1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZMIZ1 gene
    ZMIZ22  PIAS32  PIAS22  PIAS12  PIAS42  
    4 SIMAP similar genes for ZMIZ1 using alignment to 4 protein entries:     ZMIZ1_HUMAN (see all proteins):
    FLJ00092    TRAFIP10    ZMIZ2    TRAFIP20

    ZMIZ1 for paralogs           About GeneDecksing



    Genomic Variants
    for ZMIZ1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4400 NCBI SNPs in ZMIZ1 are shown (see all 4400)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 10 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs741434461,2
    		C,--74822948(+) GCCCCC/TGCCTG 1 -- us2k12Minor allele frequency- T:0.13WA 120
    rs741434471,2
    		C,--74823303(+) TTTGGG/TGGGGA 1 -- us2k13Minor allele frequency- T:0.20WA CSA 122
    rs22979231,2
    		C,F,--74823662(-) AGCGGG/AGGTGT 1 -- us2k18Minor allele frequency- A:0.17EA NA CSA WA 1719
    rs559231521,2
    		--74824277(+) GCTCCG/ACTCCG 1 -- us2k11Minor allele frequency- A:0.00NA 2
    rs122642561,2
    		--74824488(+) gcggcC/Ggggcg 1 -- ut51 ese30--------
    rs11152871,2
    		C,A,--74825058(-) TTCCCG/CGTCCT 1 -- int15Minor allele frequency- C:0.10MN CSA WA NA EA 543
    rs761846391,2
    		C,--74825155(+) CGCTGG/TGGAAA 1 -- int12Minor allele frequency- T:0.05NA 122
    rs13379831,2
    		C,--74827694(-) CGTGCG/ATGAGG 1 -- int14Minor allele frequency- A:0.12CSA WA NA EA 359
    rs46414011,2
    		C,--74827819(+) TTGCAG/AGNNNN 1 -- int15Minor allele frequency- A:0.12CSA WA NA EA 361
    rs668706341,2
    		C,F,--74827961(+) ACCTGC/TGTATA 1 -- int18Minor allele frequency- T:0.24NA WA CSA EA 366

    HapMap Linkage Disequilibrium report for ZMIZ1 (80828792 - 81076285 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for ZMIZ1
         7 CNVs: 4704 71051 2158 29867 6886 71052 29866

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    Disorders / Diseases
    for ZMIZ1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ZMIZ1 for disorders           About GeneDecksing

    OMIM gene information: 607159    OMIM disorders: --

    12 diseases for ZMIZ1:    About MalaCards
    acute lymphoblastic leukemia    lymphoblastic leukemia    inflammatory bowel disease    multiple sclerosis
    celiac disease    leukemia    vitiligo    crohn's disease
    alzheimer's disease    nephropathy    malaria    prostatitis

    Human Genome Epidemiology (HuGE) Navigator: ZMIZ1 (7 documents)

    Export disorders for ZMIZ1 gene to outside databases

    Publications
    for ZMIZ1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZMIZ1 gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with ZMIZ1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Are gene expression microarray analyses reliable? A re view of studies of retinoic acid responsive genes. (PubMed id 15626329)1, 3 van der Spek P.J....Walker M.G. (2003)
    2. hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci. (PubMed id 14609956)1, 2 Sharma M.... Sun Z. (2003)
    3. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2 Nagase T.... Ohara O. (1999)
    4. The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity. (PubMed id 16777850)1, 9 Li X....Sun Z. (2006)
    5. Combined analysis of genome-wide association studies f or Crohn disease and psoriasis identifies seven shared susceptibility loci. (PubMed id 22482804)1 Ellinghaus D....Franke A. (2012)
    6. Genome-wide meta-analysis identifies novel multiple sc lerosis susceptibility loci. (PubMed id 22190364)1 Patsopoulos N.A....de Bakker P.I. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Genetic risk and a primary role for cell-mediated immu ne mechanisms in multiple sclerosis. (PubMed id 21833088)1  ....Compston A. (2011)
    9. Association between genome-wide association studies r eported SNPs and pediatric-onset Crohn's disease in Canadian children. (PubMed id 20473688)1 Amre D.K....Levy E. (2010)
    10. Multiple common variants for celiac disease influenci ng immune gene expression. (PubMed id 20190752)1 Dubois P.C....van Heel D.A. (2010)

    External Searches for ZMIZ1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ZMIZ1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57178 HGNC: 16493 AceView: RAI17 Ensembl:ENSG00000108175 euGenes: HUgn57178
    ECgene: ZMIZ1 H-InvDB: ZMIZ1

    Other Databases showing ZMIZ1 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA1224

    Specialized Databases showing ZMIZ1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZMIZ1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ZMIZ1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ZMIZ1 gene:
    Search GeneIP for patents involving ZMIZ1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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