ZMAT5 Gene
protein-coding GIFtS: 40
GCID: GC22M030126
|
|
zinc finger, matrin-type 5
| |
Aliases
for ZMAT5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger, Matrin-Type 51 2 | | U11/U12 SnRNP 20 KDa Protein2 3 | | SNRNP201 2 | | U11/U12 SnRNP 20K2 | | U11/U12-20K2 3 | | Zinc Finger Matrin-Type Protein 52 | | U11/U12 Small Nuclear Ribonucleoprotein 20 KDa Protein2 3 | | Zinc Finger, Matrin Type 52 |
Export aliases for ZMAT5 gene to outside databasesPrevious GC identifers: GC22M028452 GC22M028456 GC22M013090 |
Summaries
for ZMAT5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ZMAT5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZMAT5 gene promoter:
TBP AML1a HOXA5 Cart-1 CUTL1 STAT5A C/EBPalpha c-Ets-1 HNF-4alpha1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZMAT5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZMAT5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22cen-q12.3 Ensembl cytogenetic band: 22q12.2 HGNC cytogenetic band: 22cen-q12.3ZMAT5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M030126: view genomic region
(about GC identifiers)
Start:
|
30,126,945 bp from pter |
End:
|
30,163,000 bp from pter |
Size:
|
36,056 bases |
Orientation:
|
minus strand |
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Proteins
for ZMAT5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZMAT5_HUMAN, Q9UDW3 (See
protein sequence)Recommended Name: Zinc finger matrin-type protein 5 Size: 170 amino acids; 19971 Da
Subunit: Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Not found in the major spliceosome
Subcellular location: Nucleus
Secondary accessions: A8K9F6Explore the universe of human proteins at neXtProt for ZMAT5: NX_Q9UDW3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UDW3
ZMAT5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001003692.1 NP_061976.1
ENSEMBL proteins: ENSP00000344241 ENSP00000380883
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ZMAT5 for ontologies About GeneDecksing
ZMAT5 Antibody Products:
Assay Products for ZMAT5: |
Protein
Domains /
Families
for ZMAT5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZMAT5 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UDW3ProtoNet protein and cluster: Q9UDW3 2 Blocks protein families: IPB000571 Zn-finger IPB003604 Zn-finger
UniProtKB/Swiss-Prot: ZMAT5_HUMAN, Q9UDW3Similarity: Contains 1 C3H1-type zinc finger |
Function
for ZMAT5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZMAT5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZMAT5 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZMAT5 (NM_019103) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZMAT5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMAT5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT5 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003676 | nucleic acid binding |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZMAT5 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for ZMAT5:
|
Pathways & Interactions
for ZMAT5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZMAT5
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
ZMAT5 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZMAT5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZMAT5
Search CenterWatch for drugs/clinical trials and news about ZMAT5
|
Transcripts
for ZMAT5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZMAT5 gene (2 alternative transcripts): NM_001003692.1 NM_019103.2 Unigene Cluster for ZMAT5: Zinc finger, matrin-type 5 Hs.713647 [show with all ESTs]Unigene Representative Sequence: BM5479093 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000344318 ENST00000489010(uc003ago.1) ENST00000397781(uc003agm.3 uc003agn.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZMAT5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZMAT5 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ZMAT5 (NM_019103) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZMAT5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMAT5 |
Additional cDNA sequence: AK292671.1 AL160311.1 BC009717.1 CR456353.1 CR457393.1 9 DOTS entries: DT.456154 DT.100026715 DT.100755430 DT.91701580 DT.100755433 DT.95224291 DT.92047643 DT.100759242 DT.97786659 24/164 AceView cDNA sequences (see all 164): AI383082 CK430232 BU584159 AL160311 BU839565 BI915248 BC009717 BQ931527 AI139242 CB160060 BU687650 BQ186218 BQ012495 BE218662 AI393350 CA944667 BX103763 AW007574 BQ013228 AA378133 BU190596 NM_019103 NM_001003692 BM684026
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZMAT5 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 |
|---|
|
| SP1: | | | | | | | - | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZMAT5
|
Expression
for ZMAT5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZMAT5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGGCTCCGA
About this image
See ZMAT5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZMAT5
SOURCE GeneReport for Unigene cluster: Hs.713647
SABiosciences Custom PCR Arrays for ZMAT5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZMAT5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZMAT5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZMAT5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZMAT5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT5 |
Orthologs
for ZMAT5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ZMAT5 gene from 8/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Zmat51 , 5 |
zinc finger, matrin type 51, 5 |
90.78(n)1
92.94(a)1 |
|
11 (2.96 cM)5
671781 NM_026015.21 NP_080291.11
47046785 |
chicken
(Gallus gallus) |
Aves |
ZMAT51 |
zinc finger, matrin type 5 |
76.08(n)
73.53(a) |
|
417017 XM_415307.3 XP_415307.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ZMAT56 |
-- |
69(a) |
1 ↔ 1 |
GL344849.1(8238-9420) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.42212 |
Xenopus laevis transcribed sequence with weak similarity more |
80.41(n) |
|
BJ037060.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zmat51 |
zinc finger, matrin type 5 |
57.59(n)
51.48(a) |
|
445314 NM_001003771.1 NP_001003771.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG319226 |
-- |
33(a) |
1 ↔ 1 |
2L(1170181-1170789) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G267496 |
nucleic acid binding / zinc ion binding protein |
25(a) |
1 ↔ 1 |
5(9398015-9399267) |
rice
(Oryza sativa) |
Liliopsida |
-- |
zinc finger matrin-type protein 5, putative, expre... |
31(a) |
1 ↔ 1 |
1(8333519-8337574) |
ENSEMBL Gene Tree for ZMAT5 (if available)
TreeFam Gene Tree for ZMAT5 (if available) |
Paralogs
for ZMAT5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZMAT5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZMAT5 (30126945 - 30163000 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZMAT5: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZMAT5 |
|
Disorders
/ Diseases
for ZMAT5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZMAT5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZMAT5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZMAT5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. (PubMed id 15146077)1, 2 Will C.L.... Luehrmann R. (2004)
- Toward a complete human genome sequence. (PubMed id 9847074)1, 3 Wilson R. (1998)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. (PubMed id 7566098)1 Adams M.D....White O. (1995)
|
External Searches for ZMAT5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZMAT5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZMAT5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZMAT5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZMAT5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZMAT5 gene:
Search GeneIP for patents involving ZMAT5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZMAT5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZMAT5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZMAT5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZMAT5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZMAT5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZMAT5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZMAT5 |
| |
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| | | | Search Tocris compounds for ZMAT5 |
| |  |  |  |  | | | | |
 |
 |
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 | | | ZMAT5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT5 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZMAT5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMAT5 |
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