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Aliases for ZMAT5 Gene

Aliases for ZMAT5 Gene

  • Zinc Finger Matrin-Type 5 2 3
  • Zinc Finger CCCH-Type Containing 19 2 2 3
  • U11/U12 Small Nuclear Ribonucleoprotein 20 KDa Protein 3 4
  • U11/U12 SnRNP 20 KDa Protein 3 4
  • Zinc Finger, Matrin-Type 5 3 5
  • U11/U12 SnRNP 20K 2 3
  • U11/U12-20K 3 4
  • SNRNP20 3
  • ZC3H19 3

External Ids for ZMAT5 Gene

Previous HGNC Symbols for ZMAT5 Gene

  • ZC3H19

Previous GeneCards Identifiers for ZMAT5 Gene

  • GC22M028452
  • GC22M028456
  • GC22M030126
  • GC22M013090

Summaries for ZMAT5 Gene

GeneCards Summary for ZMAT5 Gene

ZMAT5 (Zinc Finger Matrin-Type 5) is a Protein Coding gene. Among its related pathways are Gene Expression and mRNA Splicing - Major Pathway.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZMAT5 Gene

Genomics for ZMAT5 Gene

Regulatory Elements for ZMAT5 Gene

Promoters for ZMAT5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZMAT5 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZMAT5 Gene

29,730,956 bp from pter
29,767,068 bp from pter
36,113 bases
Minus strand

Genomic View for ZMAT5 Gene

Genes around ZMAT5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZMAT5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZMAT5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZMAT5 Gene

Proteins for ZMAT5 Gene

  • Protein details for ZMAT5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger matrin-type protein 5
    Protein Accession:
    Secondary Accessions:
    • A8K9F6

    Protein attributes for ZMAT5 Gene

    170 amino acids
    Molecular mass:
    19971 Da
    Quaternary structure:
    • Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Not found in the major spliceosome.

neXtProt entry for ZMAT5 Gene

Proteomics data for ZMAT5 Gene at MOPED

Post-translational modifications for ZMAT5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZMAT5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZMAT5 Gene

Domains & Families for ZMAT5 Gene

Gene Families for ZMAT5 Gene

Protein Domains for ZMAT5 Gene

Suggested Antigen Peptide Sequences for ZMAT5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 C3H1-type zinc finger.
  • Contains 1 C3H1-type zinc finger.
genes like me logo Genes that share domains with ZMAT5: view

Function for ZMAT5 Gene

Gene Ontology (GO) - Molecular Function for ZMAT5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZMAT5: view
genes like me logo Genes that share phenotypes with ZMAT5: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZMAT5 Gene

Localization for ZMAT5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZMAT5 Gene

Subcellular locations from

Jensen Localization Image for ZMAT5 Gene COMPARTMENTS Subcellular localization image for ZMAT5 gene
Compartment Confidence
nucleus 5
cytosol 2
extracellular 2

No data available for Gene Ontology (GO) - Cellular Components for ZMAT5 Gene

Pathways & Interactions for ZMAT5 Gene

genes like me logo Genes that share pathways with ZMAT5: view

Pathways by source for ZMAT5 Gene

Interacting Proteins for ZMAT5 Gene

Gene Ontology (GO) - Biological Process for ZMAT5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008380 RNA splicing IC,TAS 15146077
genes like me logo Genes that share ontologies with ZMAT5: view

No data available for SIGNOR curated interactions for ZMAT5 Gene

Drugs & Compounds for ZMAT5 Gene

No Compound Related Data Available

Transcripts for ZMAT5 Gene

Unigene Clusters for ZMAT5 Gene

Zinc finger, matrin-type 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZMAT5 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5
SP1: - -
SP2: -
SP3: -

Relevant External Links for ZMAT5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZMAT5 Gene

mRNA expression in normal human tissues for ZMAT5 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZMAT5 Gene

SOURCE GeneReport for Unigene cluster for ZMAT5 Gene Hs.713647

genes like me logo Genes that share expression patterns with ZMAT5: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZMAT5 Gene

Orthologs for ZMAT5 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZMAT5 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZMAT5 35
  • 91.76 (n)
  • 94.12 (a)
ZMAT5 36
  • 94 (a)
(Canis familiaris)
Mammalia ZMAT5 35
  • 92.16 (n)
  • 94.12 (a)
ZMAT5 36
  • 94 (a)
(Mus musculus)
Mammalia Zmat5 35
  • 90.78 (n)
  • 92.94 (a)
Zmat5 16
Zmat5 36
  • 93 (a)
(Pan troglodytes)
Mammalia ZMAT5 35
  • 99.61 (n)
  • 99.41 (a)
ZMAT5 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Zmat5 35
  • 89.41 (n)
  • 93.53 (a)
(Monodelphis domestica)
Mammalia ZMAT5 36
  • 77 (a)
(Gallus gallus)
Aves ZMAT5 35
  • 76.27 (n)
  • 73.53 (a)
ZMAT5 36
  • 74 (a)
(Anolis carolinensis)
Reptilia ZMAT5 36
  • 69 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.7488 35
zmat5 35
  • 61.55 (n)
  • 58.9 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.4221 35
(Danio rerio)
Actinopterygii zmat5 35
  • 57.59 (n)
  • 51.48 (a)
zmat5 36
  • 46 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9091 35
fruit fly
(Drosophila melanogaster)
Insecta CG31922 36
  • 33 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 36 (a)
Species with no ortholog for ZMAT5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZMAT5 Gene

Gene Tree for ZMAT5 (if available)
Gene Tree for ZMAT5 (if available)

Paralogs for ZMAT5 Gene

No data available for Paralogs for ZMAT5 Gene

Variants for ZMAT5 Gene

Sequence variations from dbSNP and Humsavar for ZMAT5 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs131258 -- 29,732,762(+) AAAAA(-/A)GTACA intron-variant
rs131259 -- 29,736,799(+) gcggg(C/T)ggatc intron-variant
rs131260 -- 29,736,975(+) atgag(A/C)caatt intron-variant
rs131261 -- 29,737,017(+) caaga(A/C)tccgt intron-variant
rs131262 -- 29,737,055(+) tggtg(G/T)ctcat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZMAT5 Gene

Variant ID Type Subtype PubMed ID
dgv4953n71 CNV Loss 21882294
nsv515720 CNV Gain+Loss 19592680
nsv471194 CNV Gain 18288195
nsv471195 CNV Loss 18288195
nsv914967 CNV Loss 21882294

Variation tolerance for ZMAT5 Gene

Residual Variation Intolerance Score: 34.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.90; 18.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZMAT5 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZMAT5 Gene

Disorders for ZMAT5 Gene

Relevant External Links for ZMAT5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZMAT5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZMAT5 Gene

Publications for ZMAT5 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Toward a complete human genome sequence. (PMID: 9847074) Sulston J.E. … Waterston R. (Genome Res. 1998) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks. (PMID: 24550385) Abu-Odeh M. … Aqeilan R.I. (J. Biol. Chem. 2014) 3
  5. Search for chromosome rearrangements: new approaches toward discovery of novel translocations in head and neck squamous cell carcinoma. (PMID: 22807096) Wang V.W. … Smith D.I. (Head Neck 2013) 3

Products for ZMAT5 Gene

Sources for ZMAT5 Gene

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