Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ZMAT4 Gene

protein-coding   GIFtS: 43
GCID: GC08M040388

Zinc Finger, Matrin-Type 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Zinc Finger, Matrin-Type 41 2
Zinc Finger Matrin-Type Protein 42
Zinc Finger, Matrin Type 42

External Ids:    HGNC: 258441   Entrez Gene: 796982   Ensembl: ENSG000001650617   UniProtKB: Q9H8983   

Export aliases for ZMAT4 gene to outside databases

Previous GC identifers: GC08M040508 GC08M038921


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for ZMAT4 Gene:
ZMAT4 (zinc finger, matrin-type 4) is a protein-coding gene. Diseases associated with ZMAT4 include refractive error, and myopia. An important paralog of this gene is KRCC1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000008.11  NT_167187.2  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZMAT4 gene promoter:
         ER-alpha   AML1a   CUTL1   Nkx2-5   POU6F1 (c2)   C/EBPalpha   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZMAT4 promoter sequence
   Search Chromatin IP Primers for ZMAT4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZMAT4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p11.21   Ensembl cytogenetic band:  8p11.21   HGNC cytogenetic band: 8p11.21

ZMAT4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZMAT4 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M040388:  view genomic region     (about GC identifiers)

Start:
40,388,109 bp from pter      End:
40,755,352 bp from pter
Size:
367,244 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ZMAT4_HUMAN, Q9H898 (See protein sequence)
Recommended Name: Zinc finger matrin-type protein 4  
Size: 229 amino acids; 25833 Da
Secondary accessions: Q8WUT8
Alternative splicing: 2 isoforms:  Q9H898-1   Q9H898-2   

Explore the universe of human proteins at neXtProt for ZMAT4: NX_Q9H898

Explore proteomics data for ZMAT4 at MOPED


See ZMAT4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_001129203.1  NP_078921.1  

ENSEMBL proteins: 
 ENSP00000319785   ENSP00000297737   ENSP00000428423   ENSP00000430050   ENSP00000427918  
 ENSP00000429068  

ZMAT4 Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein for ZMAT4
OriGene Protein Over-expression Lysate for ZMAT4
OriGene MassSpec for ZMAT4
OriGene Custom Protein Services for ZMAT4
GenScript Custom Purified and Recombinant Proteins Services for ZMAT4
Novus Biologicals ZMAT4 Protein
Novus Biologicals ZMAT4 Lysates
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for ZMAT4

ZMAT4 Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for ZMAT4
Novus Biologicals ZMAT4 Antibodies
Abcam antibodies for ZMAT4
Cloud-Clone Corp. Antibodies for ZMAT4
Search ThermoFisher Antibodies for ZMAT4
LSBio Antibodies in human, mouse, rat for ZMAT4

ZMAT4 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for ZMAT4
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for ZMAT4
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for ZMAT4
Cloud-Clone Corp. CLIAs for ZMAT4


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus
HGNC Gene Families:
ZMAT: Zinc fingers, matrin-type

4 InterPro protein domains:
 IPR003604 Znf_U1
 IPR015880 Znf_C2H2-like
 IPR007087 Znf_C2H2
 IPR022755 Znf_C2H2_jaz

Graphical View of Domain Structure for InterPro Entry Q9H898

ProtoNet protein and cluster: Q9H898

UniProtKB/Swiss-Prot: ZMAT4_HUMAN, Q9H898
Similarity: Contains 4 matrin-type zinc fingers


ZMAT4 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003676nucleic acid binding ----
GO:0003677DNA binding IEA--
GO:0008270zinc ion binding IEA--
     
ZMAT4 for ontologies           About GeneDecksing


Phenotypes:
     2 GenomeRNAi human phenotypes for ZMAT4:
 Decreased BPV1 E2 protein expr  Increased HPV18 LCR reporter a 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZMAT4
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZMAT4

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZMAT4
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZMAT4

miRNA
Products:
    
miRTarBase miRNAs that target ZMAT4:
hsa-mir-26b-5p (MIRT029334)

Block miRNA regulation of human, mouse, rat ZMAT4 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate ZMAT4 (see all 11):
hsa-miR-1178 hsa-miR-137 hsa-miR-499-3p hsa-miR-218 hsa-miR-1257 hsa-miR-466 hsa-miR-129-5p hsa-miR-3919
SwitchGear 3'UTR luciferase reporter plasmidZMAT4 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for ZMAT4
Predesigned siRNA for gene silencing in human, mouse, rat ZMAT4

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for ZMAT4

Clone
Products:
     
OriGene clones in human, mouse for ZMAT4 (see all 11)
OriGene ORF clones in mouse, rat for ZMAT4
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): ZMAT4 (NM_001135731)
Sino Biological Human cDNA Clone for ZMAT4
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZMAT4
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMAT4

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for ZMAT4
Browse ESI BIO Cell Lines and PureStem Progenitors for ZMAT4 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT4


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from UniProtKB/Swiss-Prot
ZMAT4_HUMAN, Q9H898: Nucleus (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus3
cytosol2

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

ZMAT4 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus




    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZMAT4
Interactions:

    Search GeneGlobe Interaction Network for ZMAT4

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ZMAT4



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for ZMAT4 gene (2 alternative transcripts): 
NM_001135731.1  NM_024645.2  

Unigene Cluster for ZMAT4:

Zinc finger, matrin-type 4
Hs.591850  [show with all ESTs]
Unigene Representative Sequence: NM_024645
9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000315769(uc003xns.3) ENST00000297737(uc003xnr.3) ENST00000519406
ENST00000519806 ENST00000518242 ENST00000523188 ENST00000523542 ENST00000522623
ENST00000523823
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat ZMAT4 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate ZMAT4 (see all 11):
hsa-miR-1178 hsa-miR-137 hsa-miR-499-3p hsa-miR-218 hsa-miR-1257 hsa-miR-466 hsa-miR-129-5p hsa-miR-3919
SwitchGear 3'UTR luciferase reporter plasmidZMAT4 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for ZMAT4
Predesigned siRNA for gene silencing in human, mouse, rat ZMAT4
Clone
Products:
     
OriGene clones in human, mouse for ZMAT4 (see all 11)
OriGene ORF clones in mouse, rat for ZMAT4
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): ZMAT4 (NM_001135731)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZMAT4
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMAT4
Primer
Products:
    
OriGene qPCR primer pairs and template standards for ZMAT4
OriGene qSTAR qPCR primer pairs in human, mouse for ZMAT4
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZMAT4
  QuantiTect SYBR Green Assays in human, mouse, rat ZMAT4
  QuantiFast Probe-based Assays in human, mouse, rat ZMAT4

Additional mRNA sequence: 

AK023904.1 BC019598.1 

3 DOTS entries:

DT.108380  DT.97838595  DT.99975931 

Selected AceView cDNA sequences (see all 41):

AI694423 AW197541 AA443144 BF513318 AA773635 AW138024 BM696997 NM_024645 
BU738684 AU141401 AV724451 BU726774 BI821509 N80841 BM661950 BM668027 
AI918138 AK023904 AW206226 AI337165 BF478133 AA443143 W07349 AL519652 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

ZMAT4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
ZMAT4 Expression
About this image

ZMAT4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ZMAT4 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.591850
    Custom PCR Arrays for ZMAT4
Primer
Products:
OriGene qPCR primer pairs and template standards for ZMAT4
OriGene qSTAR qPCR primer pairs in human, mouse for ZMAT4
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZMAT4
QuantiTect SYBR Green Assays in human, mouse, rat ZMAT4
QuantiFast Probe-based Assays in human, mouse, rat ZMAT4
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT4

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of chordates.

Orthologs for ZMAT4 gene from Selected species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Zmat41 , 5 zinc finger, matrin type 41, 5 87.05(n)1
94.76(a)1
  8 (11.50 cM)5
3201581  NM_177086.41  NP_796060.11 
 236360195 
chicken
(Gallus gallus)
Aves ZMAT41 zinc finger, matrin-type 4 76.61(n)
83.33(a)
  426786  XM_424398.4  XP_424398.3 
lizard
(Anolis carolinensis)
Reptilia ZMAT46
zinc finger, matrin-type 4
79(a)
1 ↔ 1
GL343578.1(39154-195145)
tropical clawed frog
(Xenopus tropicalis)
Amphibia LOC1004943861 zinc finger matrin-type protein 4-like 65.01(n)
66.52(a)
  100494386  XM_002936438.2  XP_002936484.2 
zebrafish
(Danio rerio)
Actinopterygii zmat4a1 zinc finger, matrin type 4a 70.32(n)
75(a)
  100270739  XM_003198634.2  XP_003198682.2 


ENSEMBL Gene Tree for ZMAT4 (if available)
TreeFam Gene Tree for ZMAT4 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
Paralogs for ZMAT4 gene
KRCC12  ZNF3462  ZMAT12  
2 SIMAP similar genes for ZMAT4 using alignment to 4 protein entries:     ZMAT4_HUMAN (see all proteins):
ZNF346    ZMAT1

ZMAT4 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Selected SNPs for ZMAT4 (see all 8125)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 8 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs132745271,2
C,F,H--40387791(+) ATTTCC/AACTAT 2 -- int116Minor allele frequency- A:0.06NS EA NA WA 2220
rs1868138081,2
--40387926(+) TCTGAA/TTATTA 2 -- int10--------
rs1162719531,2
C,F--40387934(+) TTATGG/CCCGGA 2 -- int11Minor allele frequency- C:0.01WA 118
rs724685631,2
C--40388027(+) TTTAA-/AC/AT 
        
ACACA
2 -- int11CSA 2
rs8914051,2
C,A--40388028(+) TTAAAC/TACACA 2 -- int14Minor allele frequency- T:0.14WA NA CSA 7
rs339850321,2
C--40388028(+) TTAAA-/TA    
   
/TACA
CACAC
2 -- int11NA 2
rs339881261,2
C--40388070(+) CTTTA-/GGGCAT 2 -- int10--------
rs759831411,2
C,F--40388267(+) TCCAAC/TCCCCT 2 -- ut311Minor allele frequency- T:0.02NA 120
rs1927178231,2
--40388296(+) GTGTGG/TCTCGT 2 -- ut310--------
rs7531331,2
C,F,O,A,H--40388318(-) GCCTGC/AAGAGA 2 -- ut31 ese329Minor allele frequency- A:0.15NA EA NS WA 3160

HapMap Linkage Disequilibrium report for ZMAT4 (40388109 - 40638109 bp, first 250kb of ZMAT4)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for ZMAT4 (see all 24):    About this table    
Variant IDTypeSubtypePubMed ID
nsv821546CNV Deletion20802225
esv2736920CNV Deletion23290073
esv2736919CNV Deletion23290073
esv2662604CNV Deletion23128226
esv2736914CNV Deletion23290073
esv2736916CNV Deletion23290073
esv2736915CNV Deletion23290073
esv2736913CNV Deletion23290073
esv2024539CNV Deletion18987734
esv2664427CNV Deletion23128226

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing ZMAT4
DNA2.0 Custom Variant and Variant Library Synthesis for ZMAT4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
2 diseases for ZMAT4:    About MalaCards
refractive error    myopia


ZMAT4 for disorders           About GeneDecksing

Genetic Association Database (GAD): ZMAT4
Human Genome Epidemiology (HuGE) Navigator: ZMAT4 (1 document)

Export disorders for ZMAT4 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for ZMAT4 gene integrated from 10 sources:
(articles sorted by number of sources associating them with ZMAT4)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Genome-wide association with diabetes-related traits in the Framingham Heart Study. (PubMed id 17903298)1, 4 Meigs J.B....Dupuis J. (BMC Med. Genet. 2007)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  4. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
  5. Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. (PubMed id 23396134)1 Verhoeven V.J....Hammond C.J. (Nat. Genet. 2013)
  6. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
  7. The association between the copy-number variations of ZMAT4 and hematological malignancy. (PubMed id 21269563)1 Wan J....Zhang W. (Hematology 2011)
  8. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
  9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus
Entrez Gene: 79698 HGNC: 25844 AceView: FLJ13842 Ensembl:ENSG00000165061 euGenes: HUgn79698
ECgene: ZMAT4 H-InvDB: ZMAT4

(According to HUGE)
About This Section

TryGeneCards Plus
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus
NameDescription
PharmGKB entry for ZMAT4 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section

TryGeneCards Plus
Patent Information for ZMAT4 gene:
Search GeneIP for patents involving ZMAT4

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus

 
 EMD Millipore genomic analysis products

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZMAT4  
 OriGene qPCR primer pairs and template standards for ZMAT4   OriGene Protein Over-expression Lysate for ZMAT4  
 OriGene MassSpec something-or-other for ZMAT4   OriGene clones in human, mouse for ZMAT4  
 OriGene qSTAR qPCR primer pairs in human, mouse for ZMAT4   OriGene Purified Protein for ZMAT4  
 OriGene ORF clones in mouse, rat for ZMAT4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for ZMAT4   OriGene Custom Protein Services for ZMAT4  

 
 
 Block miRNA regulation of human, mouse, rat ZMAT4 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ZMAT4
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZMAT4 Predesigned siRNA for gene silencing in human, mouse, rat ZMAT4
 QuantiFast Probe-based Assays in human, mouse, rat ZMAT4 QuantiTect SYBR Green Assays in human, mouse, rat ZMAT4
 Custom PCR Arrays for ZMAT4 Search Chromatin IP Primers for ZMAT4
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZMAT4  Search GeneGlobe Interaction Network for ZMAT4
 Regulatory tfbs in ZMAT4 promoter
 GenScript Custom Purified and Recombinant Proteins Services for ZMAT4 GenScript cDNA clones with any tag delivered in your preferred vector for ZMAT4
 GenScript Custom Assay Services for ZMAT4 GenScript Custom overexpressing Cell Line Services for ZMAT4
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for ZMAT4
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 cDNA Clones for ZMAT4
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 ZMAT4 antibodies
 ZMAT4 proteins
 ZMAT4 lysates
 Antibodies for ZMAT4
 See all of Abcam's Antibodies, Kits and Proteins for ZMAT4
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for ZMAT4
 Antibodies for ZMAT4
 ELISAs for ZMAT4
 CLIAs for ZMAT4



 Browse ESI BIO Cell Lines and PureStem Progenitors for ZMAT4
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT4
 SwitchGear 3'UTR luciferase reporter plasmids for ZMAT4
 SwitchGear Promoter luciferase reporter plasmids for ZMAT4
 Search ThermoFisher Antibodies for ZMAT4
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMAT4
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZMAT4
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZMAT4
 LSBio Antibodies in human, mouse, rat for ZMAT4
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

View Random Gene

Category
(GIFtS: )
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      ZMAT4 gene at Home site.
Version: 3.12.136 22 July 2014
hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4