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ZMAT3 Gene

protein-coding   GIFtS: 51
GCID: GC03M178735

Zinc Finger, Matrin-Type 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, Matrin-Type 31 2     P53 Target Zinc Finger Protein2
WIG12 3 5     WIG-1/PAG608 Protein2
Zinc Finger Protein WIG-12 3     Zinc Finger Matrin-Type Protein 32
PAG6082 3     Zinc Finger Protein WIG12
P53-Activated Gene 608 Protein2 3     Zinc Finger, Matrin Type 32
WIG-12     

External Ids:    HGNC: 299831   Entrez Gene: 643932   Ensembl: ENSG000001726677   OMIM: 6064525   UniProtKB: Q9HA383   

Export aliases for ZMAT3 gene to outside databases

Previous GC identifers: GC03M180225 GC03M176139


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZMAT3 Gene:
This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and
the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell
growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative
splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.
(provided by RefSeq, Jul 2008)

GeneCards Summary for ZMAT3 Gene:
ZMAT3 (zinc finger, matrin-type 3) is a protein-coding gene. Diseases associated with ZMAT3 include esophagitis, and squamous cell carcinoma. GO annotations related to this gene include RNA binding.

UniProtKB/Swiss-Prot: ZMAT3_HUMAN, Q9HA38
Function: Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory
pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the
nucleus and nucleolus




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZMAT3 gene promoter:
         Sox5   Elk-1   FOXF2   Nkx2-2   E47   GATA-1   FOXL1   AREB6   PPAR-alpha   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZMAT3 promoter sequence
   Search Chromatin IP Primers for ZMAT3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZMAT3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q26.32   Ensembl cytogenetic band:  3q26.32   HGNC cytogenetic band: 3q26.32

ZMAT3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZMAT3 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M178735:  view genomic region     (about GC identifiers)

Start:
178,735,011 bp from pter      End:
178,790,067 bp from pter
Size:
55,057 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZMAT3_HUMAN, Q9HA38 (See protein sequence)
Recommended Name: Zinc finger matrin-type protein 3  
Size: 289 amino acids; 32059 Da
Subunit: Interacts with dsRNA
Secondary accessions: B3KVA6 D3DNR1 Q96A21
Alternative splicing: 2 isoforms:  Q9HA38-1   Q9HA38-2   

Explore the universe of human proteins at neXtProt for ZMAT3: NX_Q9HA38

Explore proteomics data for ZMAT3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZMAT3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_071915.1  NP_689426.1  

    ENSEMBL proteins: 
     ENSP00000311221   ENSP00000396506   ENSP00000398920  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZMAT: Zinc fingers, matrin-type

    3 InterPro protein domains:
     IPR003604 Znf_U1
     IPR015880 Znf_C2H2-like
     IPR022755 Znf_C2H2_jaz

    Graphical View of Domain Structure for InterPro Entry Q9HA38

    ProtoNet protein and cluster: Q9HA38

    UniProtKB/Swiss-Prot: ZMAT3_HUMAN, Q9HA38
    Similarity: Contains 3 matrin-type zinc fingers


    ZMAT3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZMAT3_HUMAN, Q9HA38
    Function: Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory
    pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the
    nucleus and nucleolus
    Induction: By DNA damage in a p53/TP53-dependent manner. Up-regulated following ionizing radiation in primary
    squamous cell carcinoma of the lung and in various colon cancer cell lines

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding ----
    GO:0005515protein binding IPI18519039
    GO:0008270zinc ion binding IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    ZMAT3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZMAT3:
     Increased circadian period len 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZMAT3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZMAT3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZMAT3

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZMAT3:
    hsa-mir-192-5p (MIRT026966), hsa-mir-215-5p (MIRT024666)

    Block miRNA regulation of human, mouse, rat ZMAT3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZMAT3 (see all 143):
    hsa-miR-411* hsa-miR-576-3p hsa-miR-193a-3p hsa-miR-361-5p hsa-miR-1914* hsa-miR-106a hsa-miR-128 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidZMAT3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZMAT3

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    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZMAT3_HUMAN, Q9HA38: Nucleus. Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--

    ZMAT3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZMAT3 About    
    See pathways by source

    SuperPathContained pathways About
    1p53 signaling pathway
    p53 signaling pathway0.41

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for ZMAT3):
        p53 signaling pathway


    ZMAT3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZMAT3
    Interactions:

        GeneGlobe Interaction Network for ZMAT3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for ZMAT3 (Q9HA381, 2, 3 ENSP000003112214) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HNRNPA2B1P226261, 2, 3, ENSP000003466944EBI-2548480,EBI-299649 MINT-6542879 MINT-6542899 MINT-6542926 I2D: score=1 STRING: ENSP00000346694
    AGO2Q9UKV81, 2EBI-2548480,EBI-528269 MINT-8410974 MINT-8410991 MINT-8410958 MINT-8410942 MINT-8411008
    DHX9Q082111, 2, 3, ENSP000003565204EBI-2548480,EBI-352022 MINT-6542891 MINT-6542867 MINT-6542918 I2D: score=1 STRING: ENSP00000356520
    SMARCA2P515313, ENSP000002657734I2D: score=1 STRING: ENSP00000265773
    SNW1Q135733, ENSP000002615314I2D: score=1 STRING: ENSP00000261531
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0006974cellular response to DNA damage stimulus IEA--
    GO:0015031protein transport IEA--
    GO:0040008regulation of growth IEA--
    GO:0043065positive regulation of apoptotic process IEA--

    ZMAT3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZMAT3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZMAT3 gene (2 alternative transcripts): 
    NM_022470.3  NM_152240.2  

    Unigene Cluster for ZMAT3:

    Zinc finger, matrin-type 3
    Hs.371609  [show with all ESTs]
    Unigene Representative Sequence: NM_152240
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000311417(uc003fji.3 uc003fjg.3) ENST00000432729 ENST00000414084

    miRNA
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    Block miRNA regulation of human, mouse, rat ZMAT3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZMAT3 (see all 143):
    hsa-miR-411* hsa-miR-576-3p hsa-miR-193a-3p hsa-miR-361-5p hsa-miR-1914* hsa-miR-106a hsa-miR-128 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidZMAT3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZMAT3
    Predesigned siRNA for gene silencing in human, mouse, rat ZMAT3
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): ZMAT3 (NM_152240)
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat ZMAT3
      QuantiFast Probe-based Assays in human, mouse, rat ZMAT3

    Additional mRNA sequence: 

    AF355465.1 AK022358.1 AK056245.1 AK122768.1 AY037945.1 BC002896.2 BC036485.1 

    8 DOTS entries:

    DT.315675  DT.86997342  DT.92423327  DT.100811484  DT.100804576  DT.120871152  DT.92420955  DT.40299787 

    Selected AceView cDNA sequences (see all 50):

    AI085719 NM_022470 NM_152240 AL515795 BU168772 CA443928 BE794892 BQ775038 
    BF797456 AK122768 CN482717 AK022358 BU179951 AY037945 AA321286 BM010514 
    AW675225 BX446040 BF339314 AF355465 BF591406 BU570977 CA441228 BE207688 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ZMAT3    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b
    SP1:              -     -                                                   
    SP2:                                                                        
    SP3:                                                                        
    SP4:                                                                        


    ECgene alternative splicing isoforms for ZMAT3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZMAT3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGATTAAAAC
    ZMAT3 Expression
    About this image

    ZMAT3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZMAT3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.371609

    UniProtKB/Swiss-Prot: ZMAT3_HUMAN, Q9HA38
    Tissue specificity: Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in
    fetal brain, heart, pancreas, adrenal gland, liver or small intestine

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZMAT3 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zmat31 , 5 zinc finger matrin type 31, 5 84.84(n)1
    87.5(a)1
      3 (15.67 cM)5
    224011  NM_009517.21  NP_033543.21 
     323347985 
    chicken
    (Gallus gallus)
    Aves ZMAT31 zinc finger, matrin-type 3 77.89(n)
    80.56(a)
      425428  XM_423190.4  XP_423190.2 
    lizard
    (Anolis carolinensis)
    Reptilia ZMAT36
    zinc finger, matrin-type 3
    79(a)
    1 ↔ 1
    3(2357913-2379336)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia AL890450.22   -- 78.38(n)    AL890450.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5615351 zinc finger matrin-type protein 3-like 64.31(n)
    70.2(a)
      561535  XM_005155855.1  XP_005155912.1 


    ENSEMBL Gene Tree for ZMAT3 (if available)
    TreeFam Gene Tree for ZMAT3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZMAT3 (see all 1054)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1903391581,2
    --178734550(+) CTGTAC/TACAGA 2 -- ds50010--------
    rs1816707131,2
    --178734622(+) GTAAGA/CGTATT 2 -- ds50010--------
    rs1473146001,2
    --178734637(+) ATGTAA/GAACAC 2 -- ds50010--------
    rs1400396661,2
    C--178734812(+) GAGAAC/TGGGCA 2 -- ds50010--------
    rs766800431,2
    C,F--178734813(+) AGAACG/AGGCAG 2 -- ds50012Minor allele frequency- A:0.02CSA WA 120
    rs1123779821,2
    C--178734930(+) ACAGTC/TATCGA 2 -- ds50013Minor allele frequency- T:0.13CSA WA NA 240
    rs1498195341,2
    --178734966(+) GTGATA/GACAAT 2 -- ds50010--------
    rs1448048881,2
    --178734971(+) GACAAC/TTTACC 2 -- ds50010--------
    rs1866571951,2
    --178735051(+) TGGAAC/TACAAA 2 -- ut310--------
    rs1910013501,2
    --178735060(+) AAATGC/TGTGTT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for ZMAT3 (178735011 - 178790067 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ZMAT3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv461026CNV Gain19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZMAT3
    DNA2.0 Custom Variant and Variant Library Synthesis for ZMAT3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606452    OMIM disorders: --

    3 diseases for ZMAT3:    
    About MalaCards
    esophagitis    squamous cell carcinoma    hiv-1


    ZMAT3 for disorders           About GeneDecksing


    Export disorders for ZMAT3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZMAT3 gene, integrated from 10 sources (see all 29):
    (articles sorted by number of sources associating them with ZMAT3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and chromosomal localization of human WIG-1/PAG608 and demonstration of amplification with increased expression in primary squamous cell carcinoma of the lung. (PubMed id 11689294)1, 2, 3 Varmeh-Ziaie S.... Collins V.P. (Cancer Lett. 2001)
    2. The p53-induced Wig-1 protein binds double-stranded RNAs with structural characteristics of siRNAs and miRNAs. (PubMed id 16844115)1, 2 Mendez Vidal C.... Wiman K.G. (FEBS Lett. 2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Human wig-1, a p53 target gene that encodes a growth inhibitory zinc finger protein. (PubMed id 11571644)1, 2 Hellborg F.... Wiman K.G. (Oncogene 2001)
    5. Wig-1, a new p53-induced gene encoding a zinc finger protein. (PubMed id 9400996)1, 3 Varmeh-Ziaie S....Wiman K.G. (Oncogene 1997)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. (PubMed id 23726511)1 Xie P....Gelernter J. (Biol. Psychiatry 2013)
    8. HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3. (PubMed id 23158102)1 Kula A....Marcello A. (Virology 2013)
    9. Wig-1, a novel regulator of N-Myc mRNA and N-Myc-driven tumor growth. (PubMed id 22513872)1 Vilborg A....Wiman K.G. (amp 2012)
    10. Wig1 prevents cellular senescence by regulating p21 mRNA decay through control of RISC recruitment. (PubMed id 23085987)1 Kim B.C....Lee J.S. (EMBO J. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Free Text  

      Query String
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    OMIM
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64393 HGNC: 29983 AceView: WIG1 Ensembl:ENSG00000172667 euGenes: HUgn64393
    ECgene: ZMAT3 Kegg: 64393 H-InvDB: ZMAT3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZMAT3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZMAT3 gene:
    Search GeneIP for patents involving ZMAT3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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