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Aliases for ZMAT2 Gene

Aliases for ZMAT2 Gene

  • Zinc Finger Matrin-Type 2 2 3
  • Zinc Finger, Matrin-Type 2 3 5
  • Ptg-12 3
  • Snu23 3

External Ids for ZMAT2 Gene

Previous GeneCards Identifiers for ZMAT2 Gene

  • GC05P140060
  • GC05P135225
  • GC05P140083
  • GC05P140084
  • GC05P140089
  • GC05P140097
  • GC05P141420
  • GC05P141564

Summaries for ZMAT2 Gene

GeneCards Summary for ZMAT2 Gene

ZMAT2 (Zinc Finger Matrin-Type 2) is a Protein Coding gene. Diseases associated with ZMAT2 include chondrosarcoma, extraskeletal myxoid. Among its related pathways are mRNA Splicing - Major Pathway. GO annotations related to this gene include nucleic acid binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZMAT2 Gene

Genomics for ZMAT2 Gene

Regulatory Elements for ZMAT2 Gene

Promoters for ZMAT2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZMAT2 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZMAT2 Gene

Chromosome:
5
Start:
140,698,680 bp from pter
End:
140,706,676 bp from pter
Size:
7,997 bases
Orientation:
Plus strand

Genomic View for ZMAT2 Gene

Genes around ZMAT2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZMAT2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZMAT2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZMAT2 Gene

Proteins for ZMAT2 Gene

  • Protein details for ZMAT2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96NC0-ZMAT2_HUMAN
    Recommended name:
    Zinc finger matrin-type protein 2
    Protein Accession:
    Q96NC0

    Protein attributes for ZMAT2 Gene

    Size:
    199 amino acids
    Molecular mass:
    23612 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZMAT2 Gene

Proteomics data for ZMAT2 Gene at MOPED

Post-translational modifications for ZMAT2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZMAT2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZMAT2 Gene

Domains & Families for ZMAT2 Gene

Gene Families for ZMAT2 Gene

Protein Domains for ZMAT2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZMAT2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96NC0

UniProtKB/Swiss-Prot:

ZMAT2_HUMAN :
  • Contains 1 matrin-type zinc finger.
Similarity:
  • Contains 1 matrin-type zinc finger.
genes like me logo Genes that share domains with ZMAT2: view

Function for ZMAT2 Gene

Gene Ontology (GO) - Molecular Function for ZMAT2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003723 RNA binding IBA --
genes like me logo Genes that share ontologies with ZMAT2: view
genes like me logo Genes that share phenotypes with ZMAT2: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZMAT2 Gene

Localization for ZMAT2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZMAT2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZMAT2 Gene COMPARTMENTS Subcellular localization image for ZMAT2 gene
Compartment Confidence
nucleus 5
mitochondrion 2

No data available for Gene Ontology (GO) - Cellular Components for ZMAT2 Gene

Pathways & Interactions for ZMAT2 Gene

SuperPathways for ZMAT2 Gene

Superpath Contained pathways
1 mRNA Splicing - Major Pathway
genes like me logo Genes that share pathways with ZMAT2: view

Pathways by source for ZMAT2 Gene

1 KEGG pathway for ZMAT2 Gene

Gene Ontology (GO) - Biological Process for ZMAT2 Gene

None

No data available for SIGNOR curated interactions for ZMAT2 Gene

Drugs & Compounds for ZMAT2 Gene

No Compound Related Data Available

Transcripts for ZMAT2 Gene

mRNA/cDNA for ZMAT2 Gene

Unigene Clusters for ZMAT2 Gene

Zinc finger, matrin-type 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZMAT2 Gene

No ASD Table

Relevant External Links for ZMAT2 Gene

GeneLoc Exon Structure for
ZMAT2
ECgene alternative splicing isoforms for
ZMAT2

Expression for ZMAT2 Gene

mRNA expression in normal human tissues for ZMAT2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZMAT2 Gene

This gene is overexpressed in NK cells (12.4), CD4 Tcells (8.9), and CD8 Tcells (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZMAT2 Gene



SOURCE GeneReport for Unigene cluster for ZMAT2 Gene Hs.350194

genes like me logo Genes that share expression patterns with ZMAT2: view

Protein tissue co-expression partners for ZMAT2 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZMAT2 Gene

Orthologs for ZMAT2 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ZMAT2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZMAT2 35
  • 95.14 (n)
  • 100 (a)
ZMAT2 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZMAT2 35
  • 95.81 (n)
  • 100 (a)
ZMAT2 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zmat2 35
  • 91.79 (n)
  • 100 (a)
Zmat2 16
Zmat2 36
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZMAT2 35
  • 99.83 (n)
  • 100 (a)
ZMAT2 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zmat2 35
  • 93.63 (n)
  • 99.5 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 99 (a)
OneToMany
-- 36
  • 99 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia ZMAT2 36
  • 99 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZMAT2 35
  • 86.43 (n)
  • 97.99 (a)
ZMAT2 36
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZMAT2 36
  • 98 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.6883 35
zmat2 35
  • 77.55 (n)
  • 92.96 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.3637 35
zebrafish
(Danio rerio)
Actinopterygii wufc30d10 35
zmat2 35
  • 77.95 (n)
  • 91.41 (a)
zmat2 36
  • 90 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP006245 35
  • 63.99 (n)
  • 64.17 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11586 35
  • 67.03 (n)
  • 70.65 (a)
CG11586 36
  • 65 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea ZK686.4 35
  • 56.07 (n)
  • 50.77 (a)
snu-23 36
  • 44 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G05760 35
  • 57.07 (n)
  • 53.03 (a)
soybean
(Glycine max)
eudicotyledons Gma.8365 35
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.4536 35
barley
(Hordeum vulgare)
Liliopsida Hv.5951 35
rice
(Oryza sativa)
Liliopsida Os03g0831900 35
  • 58.25 (n)
  • 54.74 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.1075 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9251 36
  • 65 (a)
OneToOne
Species with no ortholog for ZMAT2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZMAT2 Gene

ENSEMBL:
Gene Tree for ZMAT2 (if available)
TreeFam:
Gene Tree for ZMAT2 (if available)

Paralogs for ZMAT2 Gene

No data available for Paralogs for ZMAT2 Gene

Variants for ZMAT2 Gene

Sequence variations from dbSNP and Humsavar for ZMAT2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs6848 -- 140,706,477(-) AAACA(A/T)GAGAA utr-variant-3-prime
rs6849 -- 140,706,606(-) ACCGA(A/C)GGGCT utr-variant-3-prime
rs11410 -- 140,706,497(-) CATAA(A/T)TCTTC utr-variant-3-prime
rs14803 -- 140,706,526(-) CAAAA(A/G)CCTGC utr-variant-3-prime
rs801166 -- 140,702,317(-) GACCA(C/T)TCCTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZMAT2 Gene

Variant ID Type Subtype PubMed ID
nsv830508 CNV Loss 17160897

Variation tolerance for ZMAT2 Gene

Residual Variation Intolerance Score: 39.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.09; 2.13% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZMAT2 Gene

HapMap Linkage Disequilibrium report
ZMAT2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZMAT2 Gene

Disorders for ZMAT2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZMAT2 Gene - From: DISEASES

Disorder Aliases PubMed IDs
chondrosarcoma, extraskeletal myxoid
  • extraskeletal myxoid chondrosarcoma
- elite association - COSMIC cancer census association via MalaCards
Search ZMAT2 in MalaCards View complete list of genes associated with diseases

Relevant External Links for ZMAT2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZMAT2
genes like me logo Genes that share disorders with ZMAT2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZMAT2 Gene

Publications for ZMAT2 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Development and application of a DNA microarray-based yeast two-hybrid system. (PMID: 23275563) Suter B. … Wanker E.E. (Nucleic Acids Res. 2013) 3

Products for ZMAT2 Gene

Sources for ZMAT2 Gene

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