ZMAT1 Gene
protein-coding GIFtS: 41
GCID: GC0XM101137
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zinc finger, matrin-type 1
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Aliases
for ZMAT1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger, Matrin-Type 11 2 | | KIAA17891 3 | | Zinc Finger Matrin-Type Protein 12 |
Export aliases for ZMAT1 gene to outside databasesPrevious GC identifers: GC0XM100943 GC0XM101023 GC0XM090944 |
Summaries
for ZMAT1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZMAT1:
This gene encodes a protein containing Cys2-His2 (C2H2)-type zinc fingers, which are similar to those found in thenuclear matrix protein matrin 3. Alternatively spliced transcript variants have been found for this gene. (provided byRefSeq, Jan 2012)
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Genomic Views
for ZMAT1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011651.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZMAT1 gene promoter:
TBP HFH-3 Egr-1 Nkx2-2 POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2 FOXI1 FOXJ2 (long isoform) FOXJ2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZMAT1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZMAT1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq21 Ensembl cytogenetic band: Xq22.1 HGNC cytogenetic band: Xq21ZMAT1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM101137: view genomic region
(about GC identifiers)
Start:
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101,137,260 bp from pter |
End:
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101,187,039 bp from pter |
Size:
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49,780 bases |
Orientation:
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minus strand |
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Proteins
for ZMAT1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZMAT1_HUMAN, Q5H9K5 (See
protein sequence)Recommended Name: Zinc finger matrin-type protein 1 Size: 638 amino acids; 74755 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=BAB47418.1; Type=Erroneous initiation;
Secondary accessions: Q8NDS3 Q96JN6Alternative splicing: 2 isoforms: Q5H9K5-1 Q5H9K5-2 Explore the universe of human proteins at neXtProt for ZMAT1: NX_Q5H9K5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5H9K5
ZMAT1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001011657.2
ENSEMBL proteins: ENSP00000361868 ENSP00000437529 ENSP00000413044
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZMAT1 for ontologies About GeneDecksing
ZMAT1 Antibody Products:
Assay Products for ZMAT1: |
Protein
Domains /
Families
for ZMAT1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZMAT1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5H9K5ProtoNet protein and cluster: Q5H9K5 UniProtKB/Swiss-Prot: ZMAT1_HUMAN, Q5H9K5Similarity: Contains 3 matrin-type zinc fingers |
Function
for ZMAT1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZMAT1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZMAT1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZMAT1 (NM_001011657) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZMAT1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMAT1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZMAT1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZMAT1:
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Pathways & Interactions
for ZMAT1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZMAT1
|
Drugs & Compounds
for ZMAT1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZMAT1
Search CenterWatch for drugs/clinical trials and news about ZMAT1
|
Transcripts
for ZMAT1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZMAT1 gene: NM_001011657.3 Unigene Cluster for ZMAT1: Zinc finger, matrin-type 1 Hs.496512 [show with all ESTs]Unigene Representative Sequence: BC1524706 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000372782(uc011mrl.2) ENST00000494068(uc004eim.3) ENST00000488347
ENST00000490757 ENST00000540921 ENST00000458570(uc004ein.3 uc011mrm.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZMAT1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZMAT1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZMAT1 (NM_001011657) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZMAT1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMAT1 |
Additional cDNA sequence: AB058692.1 AK094141.1 AK296520.1 AL831883.1 BC028029.1 BC045706.1 BC140920.1 BC152470.1 NR_046008.1 NR_046009.1 4 DOTS entries: DT.100751519 DT.100751520 DT.448510 DT.121304331 24/85 AceView cDNA sequences (see all 85): AL598531 AA864380 BE766387 CA450632 BE674358 AA937712 BF447849 BF438184 AI383874 H98173 BE328846 BE467954 AA459272 AA927811 AB058692 BF111188 AL119853 CD237034 BM984593 CB985445 AI985140 AI446419 BM680659 AI564282
GeneLoc Exon Structure
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Expression
for ZMAT1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZMAT1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAGATAATT
About this image
See ZMAT1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZMAT1
SOURCE GeneReport for Unigene cluster: Hs.496512
SABiosciences Custom PCR Arrays for ZMAT1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZMAT1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZMAT1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZMAT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZMAT1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT1 |
Orthologs
for ZMAT1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZMAT1 gene from 3/8 species (see all 8) About this table
ENSEMBL Gene Tree for ZMAT1 (if available)
TreeFam Gene Tree for ZMAT1 (if available) |
Paralogs
for ZMAT1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZMAT1 gene
- KRCC12 ZNF3462 ZMAT42 ZMAT32
14 SIMAP similar genes for ZMAT1 using alignment to 2 protein entries: ZMAT1_HUMAN (see all proteins):KIAA1651 NCKAP1L pp12301 C12orf76 TUBA1C COQ5
KRCC1 PFKFB3 SNRPF SH2B3 C21orf37 FP6778
ATF1 ZMAT4
ZMAT1 for paralogs About GeneDecksing
|
Genomic Variants
for ZMAT1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for ZMAT1 (101137260 - 101187039 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZMAT1: --
Locus Specific Mutation Databases (LSDB): ZMAT1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZMAT1 |
|
Disorders
/ Diseases
for ZMAT1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZMAT1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZMAT1 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with ZMAT1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (2001)
- Keep your fingers off my DNA: protein-protein interac tions mediated by C2H2 zinc finger domains. (PubMed id 18253864)1 Brayer K.J. and Segal D.J. (2008)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- Zinc finger proteins: getting a grip on RNA. (PubMed id 15718139)1 Brown R.S. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Three classes of C2H2 zinc finger proteins. (PubMed id 11361095)1 Iuchi S. (2001)
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External Searches for ZMAT1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ZMAT1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZMAT1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZMAT1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZMAT1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for ZMAT1 gene:
Search GeneIP for patents involving ZMAT1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZMAT1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZMAT1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZMAT1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZMAT1 | | | OriGene Protein Over-expression Lysate for ZMAT1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZMAT1 | | OriGene 3'-UTR Clone for ZMAT1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZMAT1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZMAT1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZMAT1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZMAT1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZMAT1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZMAT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZMAT1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZMAT1 |
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| | | | Search Tocris compounds for ZMAT1 |
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 | | | ZMAT1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZMAT1 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZMAT1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZMAT1 |
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