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Aliases for ZMAT1 Gene

Aliases for ZMAT1 Gene

  • Zinc Finger, Matrin-Type 1 2 3
  • KIAA1789 4

External Ids for ZMAT1 Gene

Previous GeneCards Identifiers for ZMAT1 Gene

  • GC0XM100943
  • GC0XM101023
  • GC0XM101137
  • GC0XM090944

Summaries for ZMAT1 Gene

Entrez Gene Summary for ZMAT1 Gene

  • This gene encodes a protein containing Cys2-His2 (C2H2)-type zinc fingers, which are similar to those found in the nuclear matrix protein matrin 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

GeneCards Summary for ZMAT1 Gene

ZMAT1 (Zinc Finger, Matrin-Type 1) is a Protein Coding gene. An important paralog of this gene is KRCC1.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZMAT1 Gene

Genomics for ZMAT1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZMAT1 Gene

Start:
101,882,288 bp from pter
End:
101,932,135 bp from pter
Size:
49,848 bases
Orientation:
Minus strand

Genomic View for ZMAT1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZMAT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZMAT1 Gene

Proteins for ZMAT1 Gene

  • Protein details for ZMAT1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5H9K5-ZMAT1_HUMAN
    Recommended name:
    Zinc finger matrin-type protein 1
    Protein Accession:
    Q5H9K5
    Secondary Accessions:
    • Q8NDS3
    • Q96JN6

    Protein attributes for ZMAT1 Gene

    Size:
    638 amino acids
    Molecular mass:
    74755 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB47418.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZMAT1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZMAT1 Gene

Proteomics data for ZMAT1 Gene at MOPED

Post-translational modifications for ZMAT1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZMAT1 Gene

Antibody Products

No data available for DME Specific Peptides for ZMAT1 Gene

Domains for ZMAT1 Gene

Gene Families for ZMAT1 Gene

HGNC:
  • ZMAT :Zinc fingers, matrin-type

Protein Domains for ZMAT1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q5H9K5

UniProtKB/Swiss-Prot:

ZMAT1_HUMAN :
  • Q5H9K5
Similarity:
  • Contains 3 matrin-type zinc fingers.
genes like me logo Genes that share domains with ZMAT1: view

Function for ZMAT1 Gene

Gene Ontology (GO) - Molecular Function for ZMAT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0008270 zinc ion binding IEA --
GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor --
genes like me logo Genes that share ontologies with ZMAT1: view

Phenotypes for ZMAT1 Gene

GenomeRNAi human phenotypes for ZMAT1:
genes like me logo Genes that share phenotypes with ZMAT1: view

Animal Model Products

miRNA for ZMAT1 Gene

miRTarBase miRNAs that target ZMAT1

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZMAT1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZMAT1 Gene

Localization for ZMAT1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZMAT1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZMAT1 Gene COMPARTMENTS Subcellular localization image for ZMAT1 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZMAT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZMAT1: view

Pathways for ZMAT1 Gene

SuperPathways for ZMAT1 Gene

No Data Available

Interacting Proteins for ZMAT1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000361868%0d%0a9606.ENSP00000327541%0d%0a9606.ENSP00000309259%0d%0a
Selected Interacting proteins: ENSP00000361868 for ZMAT1 Gene via STRING

Gene Ontology (GO) - Biological Process for ZMAT1 Gene

None

No data available for Pathways by source for ZMAT1 Gene

Transcripts for ZMAT1 Gene

Unigene Clusters for ZMAT1 Gene

Zinc finger, matrin-type 1:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZMAT1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZMAT1 Gene

No ASD Table

Relevant External Links for ZMAT1 Gene

GeneLoc Exon Structure for
ZMAT1
ECgene alternative splicing isoforms for
ZMAT1

Expression for ZMAT1 Gene

mRNA expression in normal human tissues for ZMAT1 Gene

mRNA differential expression in normal tissues according to GTEx for ZMAT1 Gene

This gene is overexpressed in Pituitary (4.0).

Protein differential expression in normal tissues for ZMAT1 Gene

This gene is overexpressed in Neutrophil (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZMAT1 Gene

SOURCE GeneReport for Unigene cluster for ZMAT1 Gene Hs.496512

genes like me logo Genes that share expressions with ZMAT1: view

Expression partners for ZMAT1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZMAT1 Gene

Orthologs for ZMAT1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZMAT1 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZMAT1 35
  • 89.89 (n)
  • 83.75 (a)
ZMAT1 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zmat1 35
  • 77.33 (n)
  • 63.32 (a)
Zmat1 16
Zmat1 36
  • 59 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC100610936 35
  • 99.63 (n)
  • 99.22 (a)
-- 36
  • 99 (a)
OneToMany
-- 36
  • 99 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zmat1 35
  • 77.05 (n)
  • 62.65 (a)
cow
(Bos Taurus)
Mammalia ZMAT1 36
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZMAT1 36
  • 42 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 43 (a)
OneToMany
-- 36
  • 59 (a)
OneToMany
chicken
(Gallus gallus)
Aves ZMAT1 36
  • 28 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZMAT1 36
  • 34 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ZMAT1 36
  • 26 (a)
OneToMany
Species with no ortholog for ZMAT1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZMAT1 Gene

ENSEMBL:
Gene Tree for ZMAT1 (if available)
TreeFam:
Gene Tree for ZMAT1 (if available)

Paralogs for ZMAT1 Gene

Paralogs for ZMAT1 Gene

Selected SIMAP similar genes for ZMAT1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZMAT1: view

Variants for ZMAT1 Gene

Sequence variations from dbSNP and Humsavar for ZMAT1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1046774 -- 101,882,824(-) GGCTA(C/T)TTTAA utr-variant-3-prime
rs2071698 -- 101,886,888(+) AGTCA(C/T)AGAGC intron-variant
rs2213322 -- 101,909,177(+) aaagg(G/T)attcc intron-variant
rs2269491 -- 101,931,293(+) CTTTC(C/T)CCATC intron-variant
rs2362752 -- 101,885,786(+) tcaag(C/T)gatcc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZMAT1 Gene

Variant ID Type Subtype PubMed ID
esv2740363 CNV Deletion 23290073
esv1733154 CNV Deletion 17803354

Relevant External Links for ZMAT1 Gene

HapMap Linkage Disequilibrium report
ZMAT1
Locus Specific Mutation Databases (LSDB)
ZMAT1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZMAT1 Gene

Disorders for ZMAT1 Gene

Relevant External Links for ZMAT1

Genetic Association Database (GAD)
ZMAT1

No disorders were found for ZMAT1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ZMAT1 Gene

Publications for ZMAT1 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 3 4
  2. Three classes of C2H2 zinc finger proteins. (PMID: 11361095) Iuchi S. (Cell. Mol. Life Sci. 2001) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Zinc finger proteins: getting a grip on RNA. (PMID: 15718139) Brown R.S. (Curr. Opin. Struct. Biol. 2005) 3

Products for ZMAT1 Gene

Sources for ZMAT1 Gene

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