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Aliases for ZKSCAN8 Gene

Aliases for ZKSCAN8 Gene

  • Zinc Finger With KRAB And SCAN Domains 8 2 3
  • Zinc Finger Protein 192 2 3 4
  • ZNF192 3 4 6
  • LD5-1 3 4
  • Zinc Finger Protein With KRAB And SCAN Domains 8 3
  • ZSCAN40 3

External Ids for ZKSCAN8 Gene

Previous HGNC Symbols for ZKSCAN8 Gene

  • ZNF192

Previous GeneCards Identifiers for ZKSCAN8 Gene

  • GC06P028115

Summaries for ZKSCAN8 Gene

GeneCards Summary for ZKSCAN8 Gene

ZKSCAN8 (Zinc Finger With KRAB And SCAN Domains 8) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF396.

UniProtKB/Swiss-Prot for ZKSCAN8 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZKSCAN8 Gene

Genomics for ZKSCAN8 Gene

Genomic Location for ZKSCAN8 Gene

28,141,910 bp from pter
28,159,472 bp from pter
17,563 bases
Plus strand

Genomic View for ZKSCAN8 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZKSCAN8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZKSCAN8 Gene

No data available for Regulatory Elements for ZKSCAN8 Gene

Proteins for ZKSCAN8 Gene

  • Protein details for ZKSCAN8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein with KRAB and SCAN domains 8
    Protein Accession:
    Secondary Accessions:
    • A1L3D4
    • B4DYF1
    • Q4VAR1
    • Q4VAR2
    • Q4VAR3
    • Q9H4T1

    Protein attributes for ZKSCAN8 Gene

    578 amino acids
    Molecular mass:
    65816 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZKSCAN8 Gene


neXtProt entry for ZKSCAN8 Gene

Proteomics data for ZKSCAN8 Gene at MOPED

Post-translational modifications for ZKSCAN8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZKSCAN8 Gene

No data available for DME Specific Peptides for ZKSCAN8 Gene

Domains for ZKSCAN8 Gene

Gene Families for ZKSCAN8 Gene

  • ZNF :Zinc fingers, C2H2-type

Graphical View of Domain Structure for InterPro Entry



  • Q15776
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZKSCAN8: view

No data available for Suggested Antigen Peptide Sequences for ZKSCAN8 Gene

Function for ZKSCAN8 Gene

Molecular function for ZKSCAN8 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZKSCAN8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZKSCAN8: view

Phenotypes for ZKSCAN8 Gene

GenomeRNAi human phenotypes for ZKSCAN8:
genes like me logo Genes that share phenotypes with ZKSCAN8: view

Animal Model Products

CRISPR Products

miRNA for ZKSCAN8 Gene

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZKSCAN8 Gene

Localization for ZKSCAN8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZKSCAN8 Gene

Gene Ontology (GO) - Cellular Components for ZKSCAN8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZKSCAN8: view

No data available for Subcellular locations from COMPARTMENTS for ZKSCAN8 Gene

Pathways for ZKSCAN8 Gene

SuperPathways for ZKSCAN8 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZKSCAN8: view

Pathways by source for ZKSCAN8 Gene

2 Reactome pathways for ZKSCAN8 Gene

Gene Ontology (GO) - Biological Process for ZKSCAN8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZKSCAN8: view

Transcripts for ZKSCAN8 Gene

Unigene Clusters for ZKSCAN8 Gene

Zinc finger with KRAB and SCAN domains 8:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZKSCAN8

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZKSCAN8
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZKSCAN8 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b
SP1: -
SP2: -
SP3: - -

Relevant External Links for ZKSCAN8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZKSCAN8 Gene

mRNA expression in normal human tissues for ZKSCAN8 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZKSCAN8 Gene

SOURCE GeneReport for Unigene cluster for ZKSCAN8 Gene Hs.57679

genes like me logo Genes that share expressions with ZKSCAN8: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZKSCAN8 Gene

Orthologs for ZKSCAN8 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZKSCAN8 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZKSCAN8 35
  • 99.6 (n)
  • 98.96 (a)
  • 99 (a)
(Bos Taurus)
Mammalia -- 36
  • 53 (a)
ZNF192 35
  • 92.96 (n)
  • 92.91 (a)
(Canis familiaris)
Mammalia ZKSCAN8 35
  • 92.78 (n)
  • 93.76 (a)
  • 94 (a)
(Mus musculus)
Mammalia Zkscan8 35
  • 87.72 (n)
  • 87.72 (a)
Zkscan8 16
Zkscan8 36
  • 86 (a)
(Monodelphis domestica)
Mammalia ZKSCAN8 36
  • 66 (a)
(Rattus norvegicus)
Mammalia Zfp192 35
  • 88.41 (n)
  • 87.89 (a)
Species with no ortholog for ZKSCAN8:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZKSCAN8 Gene

Gene Tree for ZKSCAN8 (if available)
Gene Tree for ZKSCAN8 (if available)

Paralogs for ZKSCAN8 Gene

Selected SIMAP similar genes for ZKSCAN8 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZKSCAN8: view

Variants for ZKSCAN8 Gene

Sequence variations from dbSNP and Humsavar for ZKSCAN8 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs868987 -- 28,142,370(+) GCGCT(C/T)TTTTG intron-variant, upstream-variant-2KB
rs1048319 -- 28,148,746(+) AAGGA(A/T)CATCA reference, missense, utr-variant-5-prime
rs1048320 -- 28,148,753(+) ATCAG(C/T)TAGAG reference, synonymous-codon, utr-variant-5-prime
rs1150666 -- 28,156,150(-) CACAT(A/G)TATTT utr-variant-3-prime
rs1150667 -- 28,156,285(-) CATAC(C/T)ACCCT utr-variant-3-prime

Relevant External Links for ZKSCAN8 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZKSCAN8 Gene

Disorders for ZKSCAN8 Gene

No disorders were found for ZKSCAN8 Gene.

No data available for UniProtKB/Swiss-Prot for ZKSCAN8 Gene

Publications for ZKSCAN8 Gene

  1. Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. (PMID: 9244436) Lee P.L. … Beutler E. (Genomics 1997) 3 4 23
  2. A strategy for cloning the hereditary hemochromatosis gene. (PMID: 8673473) Beutler E. … Lee P. (Blood Cells Mol. Dis. 1995) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZKSCAN8 Gene

Sources for ZKSCAN8 Gene

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