Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ZKSCAN8 Gene

protein-coding   GIFtS: 47
GCID: GC06P028115

Zinc Finger With KRAB And SCAN Domains 8

(Previous name: zinc finger protein 192)
(Previous symbol: ZNF192)
  Search for ZKSCAN8
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Zinc Finger With KRAB And SCAN Domains 81 2
ZNF1921 2 3 5
Zinc Finger Protein 1921 2 3
LD5-12 3
ZSCAN402
Zinc Finger Protein With KRAB And SCAN Domains 82

External Ids:    HGNC: 129831   Entrez Gene: 77452   Ensembl: ENSG000001983157   OMIM: 6022405   UniProtKB: Q157763   

Export aliases for ZKSCAN8 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for ZKSCAN8 Gene:
ZKSCAN8 (zinc finger with KRAB and SCAN domains 8) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF446.

UniProtKB/Swiss-Prot: ZKSC8_HUMAN, Q15776
Function: May be involved in transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NC_018917.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for ZKSCAN8
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZKSCAN8 promoter sequence
   Search Chromatin IP Primers for ZKSCAN8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZKSCAN8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p21

ZKSCAN8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZKSCAN8 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P028115:  view genomic region     (about GC identifiers)

Start:
28,109,688 bp from pter      End:
28,127,250 bp from pter
Size:
17,563 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ZKSC8_HUMAN, Q15776 (See protein sequence)
Recommended Name: Zinc finger protein with KRAB and SCAN domains 8  
Size: 578 amino acids; 65816 Da
Secondary accessions: A1L3D4 Q4VAR1 Q4VAR2 Q4VAR3 Q9H4T1

Explore the universe of human proteins at neXtProt for ZKSCAN8: NX_Q15776

Explore proteomics data for ZKSCAN8 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZKSCAN8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001265048.1  NP_001265050.1  NP_001265051.1  NP_006289.2  

    ENSEMBL proteins: 
     ENSP00000475589   ENSP00000402948   ENSP00000332750   ENSP00000439117  
    Reactome Protein details: Q15776

    ZKSCAN8 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ZKSCAN8
    GenScript Custom Purified and Recombinant Proteins Services for ZKSCAN8
    Novus Biologicals ZKSCAN8 Proteins
    Novus Biologicals ZKSCAN8 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for ZKSCAN8 

    ZKSCAN8 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZKSCAN8
    Novus Biologicals ZKSCAN8 Antibodies
    Search for Antibodies for ZKSCAN8 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    Search ThermoFisher Antibodies for ZKSCAN8
    LSBio Antibodies in human, mouse, rat for ZKSCAN8

    ZKSCAN8 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZKSCAN8
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZKSCAN8
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for ZKSCAN8 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    Selected InterPro protein domains (see all 6):
     IPR001909 Krueppel-associated_box
     IPR008916 Retrov_capsid_C
     IPR003309 Tscrpt_reg_SCAN
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd

    Graphical View of Domain Structure for InterPro Entry Q15776

    ProtoNet protein and cluster: Q15776

    3 Blocks protein domains:
    IPB001909 KRAB box
    IPB003309 Transcriptional regulator SCAN
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZKSC8_HUMAN, Q15776
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 9 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain
    Similarity: Contains 1 SCAN box domain


    Find genes that share domains with ZKSCAN8           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZKSC8_HUMAN, Q15776
    Function: May be involved in transcriptional regulation

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZKSCAN8           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ZKSCAN8:
     Low eccentricity cells 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZKSCAN8
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZKSCAN8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZKSCAN8
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZKSCAN8

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZKSCAN8:
    hsa-mir-221-3p (MIRT024197), hsa-mir-335-5p (MIRT018290), hsa-mir-877-5p (MIRT037331), hsa-mir-98-5p (MIRT027721)

    Block miRNA regulation of human, mouse, rat ZKSCAN8 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ZKSCAN8
    SwitchGear 3'UTR luciferase reporter plasmidZKSCAN8 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZKSCAN8
    Predesigned siRNA for gene silencing in human, mouse, rat ZKSCAN8

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZKSCAN8

    Clone
    Products:
         
    OriGene clones in human, mouse for ZKSCAN8 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for ZKSCAN8
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZKSCAN8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZKSCAN8

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZKSCAN8
    Browse ESI BIO Cell Lines and PureStem Progenitors for ZKSCAN8 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZKSCAN8


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    ZKSC8_HUMAN, Q15776: Nucleus (Potential)

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--
    GO:0005730nucleolus ----
    GO:0005737cytoplasm ----

    Find genes that share ontologies with ZKSCAN8           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for ZKSCAN8 About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with ZKSCAN8           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZKSCAN8
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZKSCAN8
    Interactions:

        Search GeneGlobe Interaction Network for ZKSCAN8

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for ZKSCAN8 (Q157763 ENSP000003327504) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ZNF174Q156973, ENSP000002686554I2D: score=1 STRING: ENSP00000268655
    ZNF24P170283, ENSP000002613324I2D: score=1 STRING: ENSP00000261332
    PRNPP041563I2D: score=1 
    ZNF165P499103I2D: score=1 
    --ENSP000002522064STRING: ENSP00000252206
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----

    Find genes that share ontologies with ZKSCAN8           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZKSCAN8 (ZKSC8)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ZKSCAN8 gene (4 alternative transcripts): 
    NM_001278119.1  NM_001278121.1  NM_001278122.1  NM_006298.3  

    Unigene Cluster for ZKSCAN8:

    Zinc finger with KRAB and SCAN domains 8
    Hs.57679  [show with all ESTs]
    Unigene Representative Sequence: NM_006298
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000606198 ENST00000457389 ENST00000330236(uc003nkn.1 uc010jqx.1 uc010jqy.1 uc011dkz.1)
    ENST00000536028
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZKSCAN8 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ZKSCAN8
    SwitchGear 3'UTR luciferase reporter plasmidZKSCAN8 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZKSCAN8
    Predesigned siRNA for gene silencing in human, mouse, rat ZKSCAN8
    Clone
    Products:
         
    OriGene clones in human, mouse for ZKSCAN8 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for ZKSCAN8
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZKSCAN8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZKSCAN8
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ZKSCAN8
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ZKSCAN8
      QuantiTect SYBR Green Assays in human, mouse, rat ZKSCAN8
      QuantiFast Probe-based Assays in human, mouse, rat ZKSCAN8

    Additional mRNA sequence: 

    AB208793.1 AK302402.1 BC096282.3 BC096283.3 BC096284.3 BC113961.1 BC130032.1 BC152378.1 
    U57796.1 

    3 DOTS entries:

    DT.306471  DT.100709290  DT.92007421 

    Selected AceView cDNA sequences (see all 102):

    BX107865 AI493843 AA453245 BX495565 AI002421 AA856663 BF446148 BM664529 
    BM729174 BX953436 AW292761 BU077939 CR606559 AA879100 AI302309 AW512745 
    BM783854 BM696011 AA814747 NM_006298 BM752213 AA722772 AW104801 BF446527 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ZKSCAN8    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b
    SP1:                          -                                 
    SP2:              -                                             
    SP3:              -           -                                 


    ECgene alternative splicing isoforms for ZKSCAN8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ZKSCAN8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZKSCAN8 Expression
    About this image

    ZKSCAN8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZKSCAN8 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.57679
        Custom PCR Arrays for ZKSCAN8
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ZKSCAN8
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ZKSCAN8
    QuantiTect SYBR Green Assays in human, mouse, rat ZKSCAN8
    QuantiFast Probe-based Assays in human, mouse, rat ZKSCAN8
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZKSCAN8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of human and mouse.

    Orthologs for ZKSCAN8 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zkscan81 , 5 zinc finger protein 1925
    zinc finger with KRAB and SCAN domains 81
    87.72(n)1
    87.72(a)1
      13 (7.84 cM)5
    936811  NM_139141.41  NP_631880.21 
     215132225 


    ENSEMBL Gene Tree for ZKSCAN8 (if available)
    TreeFam Gene Tree for ZKSCAN8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ZKSCAN8 gene
    ZNF4462  ZSCAN92  ZKSCAN12  ZNF3972  ZNF5002  ZNF2132  ZNF2322  ZSCAN302  
    ZNF1742  ZNF32  ZKSCAN42  ZNF3962  ZSCAN122  ZNF3942  ZSCAN212  ZSCAN232  
    ZNF1652  ZSCAN162  ZSCAN222  ZSCAN312  ZNF242  ZKSCAN32  ZNF182  
    Selected SIMAP similar genes for ZKSCAN8 using alignment to 2 protein entries:     ZKSC8_HUMAN (see all proteins) (see all similar genes):
    SCAND1    ZNF444    ZNF211    DKFZp666C237    HZF30    HZF36
    ZNF383    DKFZp571N1833    DKFZp686H20223    DKFZp686O111    ZFS-1    ZNF134
    ZNF23    ZNF354A    ZNF417    ZNF479    ZNF585B    ZNF658

    Find genes that share paralogs with ZKSCAN8           About GenesLikeMe


    5 Pseudogenes.org Pseudogenes for ZKSCAN8
    PGOHUM00000262943 PGOHUM00000243544 PGOHUM00000250201 PGOHUM00000249529 PGOHUM00000249818


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ZKSCAN8 (see all 410)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1998384621,2
    --28107767(+) GACTT-/AAAAAA 3 -- us2k10--------
    rs37571851,2
    C,F,A--28107776(-) AATAAA/TTTTTT 3 -- us2k1 tfbs36Minor allele frequency- T:0.28WA NA EA 364
    rs1427102971,2
    --28107797(+) TGTTGA/GGACAG 3 -- us2k10--------
    rs1922304001,2
    --28108014(+) CTCAGG/TTGATC 4 -- us2k10--------
    rs1853536021,2
    --28108066(+) CACCGC/TGCTCA 4 -- us2k10--------
    rs1151646881,2
    F--28108067(+) ACCGCG/ACTCAG 4 -- us2k11Minor allele frequency- A:0.01WA 118
    rs19048411,2
    C,F,A,H--28108085(-) TAAAAG/ATAACT 4 -- us2k1 tfbs39Minor allele frequency- A:0.25NS EA WA CSA NA 662
    rs1894670481,2
    C--28108103(+) AAAAAA/GGAAAC 4 -- us2k10--------
    rs1813913481,2
    --28108168(+) AAAGCA/GACAGC 4 -- us2k10--------
    rs19048401,2
    C,F,A,H--28108232(-) ACACTG/AGGAAG 4 -- us2k119Minor allele frequency- A:0.24MN NS EA WA CSA NA 2524

    HapMap Linkage Disequilibrium report for ZKSCAN8 (28109688 - 28127250 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ZKSCAN8: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZKSCAN8
    DNA2.0 Custom Variant and Variant Library Synthesis for ZKSCAN8

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 602240    OMIM disorders: --


    Find genes that share disorders with ZKSCAN8           About GenesLikeMe


    Export disorders for ZKSCAN8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ZKSCAN8 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with ZKSCAN8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. (PubMed id 9244436)1, 2, 9 Lee P.L.... Beutler E. (Genomics 1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    4. A strategy for cloning the hereditary hemochromatosis gene. (PubMed id 8673473)1, 2 Beutler E.... Lee P. (Blood Cells Mol. Dis. 1995)
    5. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    6. Protein microarray analysis identifies human cellular prion protein interactors. (PubMed id 18482256)1 Satoh J....Tabunoki H. (Neuropathol. Appl. Neurobiol. 2009)
    7. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 7745 HGNC: 12983 AceView: ZNF192 Ensembl:ENSG00000198315 euGenes: HUgn7745
    ECgene: ZKSCAN8 H-InvDB: ZKSCAN8

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ZKSCAN8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ZKSCAN8 gene:
    Search GeneIP for patents involving ZKSCAN8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZKSCAN8  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ZKSCAN8  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZKSCAN8   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZKSCAN8   OriGene Custom Protein Services for ZKSCAN8  

     
     
     Block miRNA regulation of human, mouse, rat ZKSCAN8 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ZKSCAN8
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZKSCAN8 Predesigned siRNA for gene silencing in human, mouse, rat ZKSCAN8
     QuantiFast Probe-based Assays in human, mouse, rat ZKSCAN8 QuantiTect SYBR Green Assays in human, mouse, rat ZKSCAN8
     Custom PCR Arrays for ZKSCAN8 Search Chromatin IP Primers for ZKSCAN8
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ZKSCAN8 Search GeneGlobe Interaction Network for ZKSCAN8
     Search Regulatory tfbs for ZKSCAN8
     GenScript Custom Purified and Recombinant Proteins Services for ZKSCAN8 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for ZKSCAN8
     GenScript Custom Assay Services for ZKSCAN8 GenScript Custom overexpressing Cell Line Services for ZKSCAN8
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ZKSCAN8 (ZKSC8)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ZKSCAN8 antibodies
     ZKSCAN8 proteins
     ZKSCAN8 lysates
     Search for Antibodies for ZKSCAN8 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ZKSCAN8
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for ZKSCAN8
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZKSCAN8
     SwitchGear 3'UTR luciferase reporter plasmids for ZKSCAN8
     SwitchGear Promoter luciferase reporter plasmids for ZKSCAN8
     Search ThermoFisher Antibodies for ZKSCAN8
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZKSCAN8
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZKSCAN8
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZKSCAN8
     LSBio Antibodies in human, mouse, rat for ZKSCAN8
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ZKSCAN8
      Search eBioscience for proteins for ZKSCAN8
      Search eBioscience for elisas for ZKSCAN8
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZKSCAN8 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4