Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZKSCAN7 Gene

Aliases for ZKSCAN7 Gene

  • Zinc Finger With KRAB And SCAN Domains 7 2 3
  • Zinc Finger Protein 448 2 3 4
  • Zinc Finger Protein 167 2 3 4
  • Zinc Finger Protein 64 2 3 4
  • ZNF167 3 4
  • ZNF448 3 4
  • ZNF64 3 4
  • Zinc Finger Protein With KRAB And SCAN Domains 7 3
  • ZSCAN39 3
  • ZFP 3

External Ids for ZKSCAN7 Gene

Previous HGNC Symbols for ZKSCAN7 Gene

  • ZNF64
  • ZNF448
  • ZNF167

Previous GeneCards Identifiers for ZKSCAN7 Gene

  • GC03P044597

Summaries for ZKSCAN7 Gene

GeneCards Summary for ZKSCAN7 Gene

ZKSCAN7 (Zinc Finger With KRAB And SCAN Domains 7) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF10.

UniProtKB/Swiss-Prot for ZKSCAN7 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZKSCAN7 Gene

Genomics for ZKSCAN7 Gene

Genomic Location for ZKSCAN7 Gene

Start:
44,555,175 bp from pter
End:
44,583,483 bp from pter
Size:
28,309 bases
Orientation:
Plus strand

Genomic View for ZKSCAN7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZKSCAN7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZKSCAN7 Gene

No data available for Regulatory Elements for ZKSCAN7 Gene

Proteins for ZKSCAN7 Gene

  • Protein details for ZKSCAN7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P0L1-ZKSC7_HUMAN
    Recommended name:
    Zinc finger protein with KRAB and SCAN domains 7
    Protein Accession:
    Q9P0L1
    Secondary Accessions:
    • A0PJV3
    • A8K5H0
    • Q6WL09
    • Q96FQ2

    Protein attributes for ZKSCAN7 Gene

    Size:
    754 amino acids
    Molecular mass:
    85033 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZKSCAN7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZKSCAN7 Gene

Proteomics data for ZKSCAN7 Gene at MOPED

Post-translational modifications for ZKSCAN7 Gene

  • Ubiquitination at Lys636
  • Modification sites at PhosphoSitePlus

Other Protein References for ZKSCAN7 Gene

No data available for DME Specific Peptides for ZKSCAN7 Gene

Domains for ZKSCAN7 Gene

Gene Families for ZKSCAN7 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Graphical View of Domain Structure for InterPro Entry

Q9P0L1

UniProtKB/Swiss-Prot:

ZKSC7_HUMAN :
  • Q9P0L1
Domain:
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZKSCAN7: view

No data available for Suggested Antigen Peptide Sequences for ZKSCAN7 Gene

Function for ZKSCAN7 Gene

Molecular function for ZKSCAN7 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZKSCAN7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZKSCAN7: view

Animal Model Products

CRISPR Products

miRNA for ZKSCAN7 Gene

miRTarBase miRNAs that target ZKSCAN7

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZKSCAN7 Gene

Localization for ZKSCAN7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZKSCAN7 Gene

Gene Ontology (GO) - Cellular Components for ZKSCAN7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZKSCAN7: view

No data available for Subcellular locations from COMPARTMENTS for ZKSCAN7 Gene

Pathways for ZKSCAN7 Gene

SuperPathways for ZKSCAN7 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZKSCAN7: view

Pathways by source for ZKSCAN7 Gene

2 Reactome pathways for ZKSCAN7 Gene

Gene Ontology (GO) - Biological Process for ZKSCAN7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZKSCAN7: view

Compounds for ZKSCAN7 Gene

(4) Novoseek inferred chemical compound relationships for ZKSCAN7 Gene

Compound -log(P) Hits PubMed IDs
zinc 75 20
histidine 31.8 1
cysteine 17.9 1
lead 14.5 1
genes like me logo Genes that share compounds with ZKSCAN7: view

Transcripts for ZKSCAN7 Gene

Unigene Clusters for ZKSCAN7 Gene

Zinc finger with KRAB and SCAN domains 7:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZKSCAN7

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZKSCAN7
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZKSCAN7 Gene

No ASD Table

Relevant External Links for ZKSCAN7 Gene

GeneLoc Exon Structure for
ZKSCAN7
ECgene alternative splicing isoforms for
ZKSCAN7

Expression for ZKSCAN7 Gene

mRNA expression in normal human tissues for ZKSCAN7 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZKSCAN7 Gene

SOURCE GeneReport for Unigene cluster for ZKSCAN7 Gene Hs.529512

genes like me logo Genes that share expressions with ZKSCAN7: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZKSCAN7 Gene

Orthologs for ZKSCAN7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZKSCAN7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZKSCAN7 36
  • 99 (a)
OneToOne
ZNF167 35
  • 99.42 (n)
  • 99.2 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 81 (a)
OneToMany
ZNF167 35
  • 84.68 (n)
  • 81.01 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 58 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zkscan7 35
  • 79.53 (n)
  • 72.42 (a)
Zkscan7 16
Zkscan7 36
  • 73 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 52 (a)
ManyToMany
-- 36
  • 56 (a)
ManyToMany
-- 36
  • 37 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Zfp167 35
  • 80.21 (n)
  • 75.31 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 46 (a)
OneToMany
ZNF167 35
  • 56.96 (n)
  • 52.02 (a)
Species with no ortholog for ZKSCAN7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZKSCAN7 Gene

ENSEMBL:
Gene Tree for ZKSCAN7 (if available)
TreeFam:
Gene Tree for ZKSCAN7 (if available)

Paralogs for ZKSCAN7 Gene

Selected SIMAP similar genes for ZKSCAN7 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZKSCAN7 Gene

genes like me logo Genes that share paralogs with ZKSCAN7: view

Variants for ZKSCAN7 Gene

Sequence variations from dbSNP and Humsavar for ZKSCAN7 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1966821 -- 44,572,723(-) acagg(C/G/T)gcccc intron-variant
rs2034475 -- 44,571,522(-) TTACT(A/C)CTACT utr-variant-3-prime, intron-variant
rs2034476 -- 44,571,403(-) AGGTC(C/G)TTGCT utr-variant-3-prime, intron-variant
rs2293600 -- 44,557,611(-) AAACT(A/C)TTTTC intron-variant
rs3080634 -- 44,572,347(-) acaca(-/CA)aAATC intron-variant, downstream-variant-500B

Relevant External Links for ZKSCAN7 Gene

HapMap Linkage Disequilibrium report
ZKSCAN7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZKSCAN7 Gene

Disorders for ZKSCAN7 Gene

(1) Novoseek inferred disease relationships for ZKSCAN7 Gene

Disease -log(P) Hits PubMed IDs
cancer 0 2
genes like me logo Genes that share disorders with ZKSCAN7: view

No data available for UniProtKB/Swiss-Prot for ZKSCAN7 Gene

Publications for ZKSCAN7 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PMID: 1505991) Lichter P. … Ward D.C. (Genomics 1992) 2 3
  4. Positional cloning of cDNAs from the human chromosome 3p21-22 region identifies a clustered organization of zinc-finger genes. (PMID: 7814019) CalabrA^ V. … Lania L. (Hum. Genet. 1995) 2 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZKSCAN7 Gene

Sources for ZKSCAN7 Gene

Back to Top

Content