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ZKSCAN5 Gene

protein-coding   GIFtS: 57
GCID: GC07P099102

Zinc Finger With KRAB And SCAN Domains 5

(Previous names: zinc finger protein homologous to Zfp95 in mouse, zinc finger...)
(Previous symbol: ZFP95)
  See ZKSCAN5-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger With KRAB And SCAN Domains 51 2     ZNF9142
ZFP951 2 3 5     ZSCAN372
Zinc Finger Protein Homologous To Zfp95 In Mouse1 2     zfp-952
Zinc Finger Protein 95 Homolog2 3     Zinc Finger Protein With KRAB And SCAN Domains 52
KIAA10153 5     Zfp-953
Zinc Finger Protein 95 Homolog (Mouse)1     

External Ids:    HGNC: 128671   Entrez Gene: 236602   Ensembl: ENSG000001966527   OMIM: 6112725   UniProtKB: Q9Y2L83   

Export aliases for ZKSCAN5 gene to outside databases

Previous GC identifers: GC07P098941 GC07P093738


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZKSCAN5 Gene:
This gene encodes a zinc finger protein of the Kruppel family. The protein contains a SCAN box and a KRAB A
domain. A similar protein in mouse is differentially expressed in spermatogenesis. Two alternatively spliced
transcript variants differing only in the 5' UTR have been described. Additional variants have been found, but
their full-length sequences have not been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for ZKSCAN5 Gene:
ZKSCAN5 (zinc finger with KRAB and SCAN domains 5) is a protein-coding gene. Diseases associated with ZKSCAN5 include pharyngitis. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF444.

UniProtKB/Swiss-Prot: ZKSC5_HUMAN, Q9Y2L8
Function: May be involved in transcriptional regulation

Gene Wiki entry for ZKSCAN5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZKSCAN5 gene promoter:
         Nkx3-1   ATF-2   Nkx3-1 v1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): ZKSCAN5 promoter sequence
   Search Chromatin IP Primers for ZKSCAN5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZKSCAN5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22

ZKSCAN5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZKSCAN5 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P099102:  view genomic region     (about GC identifiers)

Start:
99,102,273 bp from pter      End:
99,132,323 bp from pter
Size:
30,051 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 98,462,045-98,491,238     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZKSC5_HUMAN, Q9Y2L8 (See protein sequence)
Recommended Name: Zinc finger protein with KRAB and SCAN domains 5  
Size: 839 amino acids; 96903 Da
Sequence caution: Sequence=BAA76859.2; Type=Erroneous initiation;
Selected PDB 3D structures from and Proteopedia for ZKSCAN5 (see all 9):
2EM5 (3D)        2EMM (3D)        2EMZ (3D)        2EN3 (3D)        2EOM (3D)        2EON (3D)    
Secondary accessions: A4D280 D6W5S9

Explore the universe of human proteins at neXtProt for ZKSCAN5: NX_Q9Y2L8

Explore proteomics data for ZKSCAN5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZKSCAN5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_055384.1  NP_659570.1  

    ENSEMBL proteins: 
     ENSP00000322872   ENSP00000392104   ENSP00000377725   ENSP00000405716  
    Reactome Protein details: Q9Y2L8

    ZKSCAN5 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for ZKSCAN5

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    Selected InterPro protein domains (see all 6):
     IPR001909 Krueppel-associated_box
     IPR008916 Retrov_capsid_C
     IPR003309 Tscrpt_reg_SCAN
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd

    Graphical View of Domain Structure for InterPro Entry Q9Y2L8

    ProtoNet protein and cluster: Q9Y2L8

    2 Blocks protein domains:
    IPB001909 KRAB box
    IPB003309 Transcriptional regulator SCAN


    UniProtKB/Swiss-Prot: ZKSC5_HUMAN, Q9Y2L8
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 13 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain
    Similarity: Contains 1 SCAN box domain


    Find genes that share domains with ZKSCAN5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZKSC5_HUMAN, Q9Y2L8
    Function: May be involved in transcriptional regulation

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity NAS10585779
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding NAS10585779
         
    Find genes that share ontologies with ZKSCAN5           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZKSCAN5
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZKSCAN5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZKSCAN5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZKSCAN5

    miRNA
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    miRTarBase miRNAs that target ZKSCAN5:
    hsa-mir-155-5p (MIRT021052)

    Block miRNA regulation of human, mouse, rat ZKSCAN5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZKSCAN5 (see all 24):
    hsa-miR-140-5p hsa-miR-607 hsa-miR-125a-5p hsa-let-7d hsa-miR-202 hsa-let-7c hsa-let-7g hsa-miR-214*
    SwitchGear 3'UTR luciferase reporter plasmidZKSCAN5 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZKSCAN5
    Predesigned siRNA for gene silencing in human, mouse, rat ZKSCAN5

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): ZKSCAN5 (NM_014569)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZKSCAN5
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    Browse ESI BIO Cell Lines and PureStem Progenitors for ZKSCAN5 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZKSCAN5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZKSC5_HUMAN, Q9Y2L8: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus NAS10585779

    Find genes that share ontologies with ZKSCAN5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZKSCAN5 About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with ZKSCAN5           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZKSCAN5
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZKSCAN5
    Interactions:

        Search GeneGlobe Interaction Network for ZKSCAN5

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for ZKSCAN5 (Q9Y2L81, 2, 3 ENSP000003228724) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNNT1P138052, 3, ENSP000002919014MINT-8275138 I2D: score=2 STRING: ENSP00000291901
    ZBTB9Q96C003, ENSP000003785034I2D: score=1 STRING: ENSP00000378503
    ENSG00000236515Q96C003I2D: score=1 
    ZSCAN1Q8NBB43, ENSP000002823264I2D: score=1 STRING: ENSP00000282326
    SUV39H1O434631EBI-2876965,EBI-349968
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated NAS10585779

    Find genes that share ontologies with ZKSCAN5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZKSCAN5 (ZKSC5)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZKSCAN5 gene (2 alternative transcripts): 
    NM_014569.3  NM_145102.2  

    Unigene Cluster for ZKSCAN5:

    Zinc finger with KRAB and SCAN domains 5
    Hs.110839  [show with all ESTs]
    Unigene Representative Sequence: BX648490
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000326775(uc003uqv.3 uc010lfx.3) ENST00000451158 ENST00000394170(uc003uqw.3 uc003uqx.3)
    ENST00000454175(uc003uqy.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZKSCAN5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZKSCAN5 (see all 24):
    hsa-miR-140-5p hsa-miR-607 hsa-miR-125a-5p hsa-let-7d hsa-miR-202 hsa-let-7c hsa-let-7g hsa-miR-214*
    SwitchGear 3'UTR luciferase reporter plasmidZKSCAN5 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZKSCAN5
    Predesigned siRNA for gene silencing in human, mouse, rat ZKSCAN5
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ZKSCAN5 (NM_014569)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZKSCAN5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZKSCAN5
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ZKSCAN5
    OriGene qSTAR qPCR primer pairs in human, mouse for ZKSCAN5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZKSCAN5
      QuantiTect SYBR Green Assays in human, mouse, rat ZKSCAN5
      QuantiFast Probe-based Assays in human, mouse, rat ZKSCAN5

    Additional mRNA sequence: 

    AB023232.1 AB742315.1 AB742316.1 AB742317.1 AB742318.1 AF170025.1 AK027714.1 AK096552.1 
    BC030790.2 BX648490.1 

    7 DOTS entries:

    DT.91761181  DT.75102186  DT.97826865  DT.97804549  DT.95308584  DT.99932427  DT.100810046 

    Selected AceView cDNA sequences (see all 32):

    BU944630 BU162200 CF137397 BM921189 BG722929 AL702923 BE298739 BU189591 
    BX509662 BG748931 AL705852 AL705809 BE795688 BU431272 BC015622 AA309090 
    AK027714 NM_145102 AB023232 NM_014569 BC030790 BG829396 CB147662 BX648490 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ZKSCAN5    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8
    SP1:        -     -                                                         
    SP2:        -                                                               
    SP3:              -                                                         
    SP4:        -     -                       -     -                           
    SP5:                                            -                           


    ECgene alternative splicing isoforms for ZKSCAN5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZKSCAN5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTGAGAGAG
    ZKSCAN5 Expression
    About this image

    ZKSCAN5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZKSCAN5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.110839
        Custom PCR Arrays for ZKSCAN5
    Primer
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    QuantiTect SYBR Green Assays in human, mouse, rat ZKSCAN5
    QuantiFast Probe-based Assays in human, mouse, rat ZKSCAN5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZKSCAN5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ZKSCAN5 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zkscan51 , 5 zinc finger with KRAB and SCAN domains 51, 5 80.4(n)1
    80.93(a)1
      5 (85.14 cM)5
    227571  NM_016683.21  NP_057892.21 
     1452045625 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(3)neo386
    CG73686
    --
    17(a)
    15(a)
    many ↔ many
    many ↔ many
    3R(7590760-7604886)
    3L(11590302-11598474)


    ENSEMBL Gene Tree for ZKSCAN5 (if available)
    TreeFam Gene Tree for ZKSCAN5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZKSCAN5 gene
    ZNF4442  
    Selected SIMAP similar genes for ZKSCAN5 using alignment to 8 protein entries:     ZKSC5_HUMAN (see all proteins) (see all similar genes):
    ZFP95    SCAND1    KRBOX4    ZNF674    ZSCAN32    ZNF124
    ZSCAN29    ZNF500    ZNF697    ZNF78L1    ZNF444    ZNF
    ZFP41    ZNF702P    ZSCAN30    ZSCAN18    ZNF548    ZNF24

    Find genes that share paralogs with ZKSCAN5           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZKSCAN5 (see all 651)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs779111431,2
    C,F--99100280(+) CAAAAG/CGTGTT 1 -- us2k11Minor allele frequency- C:0.50WA 2
    rs1824198541,2
    --99100377(+) AGATGA/GAGACC 1 -- us2k10--------
    rs1870736951,2
    C--99100604(+) CAAACA/GAATAA 2 -- us2k10--------
    rs1494873751,2
    --99100615(+) ATAAAG/TCATTT 2 -- us2k10--------
    rs1916755141,2
    --99100641(+) TATTAG/TAAAAG 2 -- us2k10--------
    rs1439333821,2
    --99100842(+) TTTTTA/GTAGAG 2 -- us2k10--------
    rs1486648441,2
    --99100906(+) CACCTC/TGGCCT 2 -- us2k10--------
    rs1827240981,2
    --99100935(+) CAGGCA/GTGAGC 2 -- us2k10--------
    rs1884933191,2
    --99100978(+) ATTAAA/GCAACT 2 -- us2k10--------
    rs1443697831,2
    --99100990(+) TATACA/GAGCAA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZKSCAN5 (99102273 - 99132323 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ZKSCAN5:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2675875CNV Deletion23128226
    esv2662144CNV Deletion23128226
    esv2734884CNV Deletion23290073
    nsv824229CNV Loss20364138
    nsv831069CNV Loss17160897
    nsv819741CNV Gain19587683

    Human Gene Mutation Database (HGMD): ZKSCAN5
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing ZKSCAN5
    DNA2.0 Custom Variant and Variant Library Synthesis for ZKSCAN5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611272    OMIM disorders: --

    1 disease for ZKSCAN5:    
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    pharyngitis

    1 disease from the University of Copenhagen DISEASES database for ZKSCAN5:
    Pharyngitis

    Find genes that share disorders with ZKSCAN5           About GenesLikeMe

    Genetic Association Database (GAD): ZKSCAN5

    Export disorders for ZKSCAN5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZKSCAN5 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with ZKSCAN5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation, characterization, and mapping of a zinc finger gene, ZFP95, containing both a SCAN box and an alternatively spliced KRAB A domain. (PubMed id 10585779)1, 2, 3, 9 Dreyer S.D.... Lee B. (Genomics 1999)
    2. Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. (PubMed id 21533175)1, 4 Zhai G....Wallaschofski H. (PLoS Genet. 2011)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    4. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2 Nagase T.... Ohara O. (DNA Res. 1999)
    5. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    8. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (Cell 2010)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. Sequence diversity and haplotype structure at the human CYP3A cluster. (PubMed id 16314882)1 Thompson E.E....Di Rienzo A. (Pharmacogenomics J. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23660 HGNC: 12867 AceView: ZFP95 Ensembl:ENSG00000196652 euGenes: HUgn23660
    ECgene: ZKSCAN5 H-InvDB: ZKSCAN5

    (According to HUGE)
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    HUGE: KIAA1015

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZKSCAN5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZKSCAN5 gene:
    Search GeneIP for patents involving ZKSCAN5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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