Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZKSCAN4 Gene

protein-coding   GIFtS: 53
GCID: GC06M028212

Zinc Finger With KRAB And SCAN Domains 4

(Previous names: zinc finger protein 307, zinc finger protein 427)
(Previous symbols: ZNF307, ZNF427)
Microbiology & Infectious Diseases Congress
  Search for ZKSCAN4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger With KRAB And SCAN Domains 41 2     p373c6.12
ZNF3071 2 3 5     P373c6.1 (Novel C2H2 Type Zinc Finger Protein)2
Zinc Finger Protein 3071 2 3     Zinc Finger Protein With KRAB And SCAN Domains 42
Zinc Finger Protein 4271 2 3     P373c6.13
ZNF4271 2 3     EC 2.1.1.438
P1P373C62     EC 4.2.1.528
ZSCAN362     

External Ids:    HGNC: 138541   Entrez Gene: 3870322   Ensembl: ENSG000001876267   OMIM: 6116435   UniProtKB: Q969J23   

Export aliases for ZKSCAN4 gene to outside databases

Previous GC identifers: GC06M028324 GC06M028021


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZKSCAN4 Gene: 
ZKSCAN4 (zinc finger with KRAB and SCAN domains 4) is a protein-coding gene. Among its related super-pathways are Gene Expression. GO annotations related to this gene include DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF446.

UniProtKB/Swiss-Prot: ZKSC4_HUMAN, Q969J2
Function: May be involved in the transcriptional activation of MDM2 and EP300 genes




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZKSCAN4 gene promoter:
         p53   Brachyury   p300   LUN-1   LCR-F1   Roaz   c-Ets-1   C/EBPalpha   GATA-1   AREB6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZKSCAN4 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZKSCAN4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZKSCAN4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p21

ZKSCAN4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZKSCAN4 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M028212:  view genomic region     (about GC identifiers)

Start:
28,212,401 bp from pter      End:
28,227,011 bp from pter
Size:
14,611 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZKSC4_HUMAN, Q969J2 (See protein sequence)
Recommended Name: Zinc finger protein with KRAB and SCAN domains 4  
Size: 545 amino acids; 61579 Da
Subcellular location: Nucleus
Secondary accessions: B2RE32 Q5U7L4

Explore the universe of human proteins at neXtProt for ZKSCAN4: NX_Q969J2

Explore proteomics data for ZKSCAN4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q969J2

  • 2 DME Specific Peptides for ZKSCAN4 (Q969J2)
     RLRELCG  HQRTHTGEKPY 

    ZKSCAN4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZKSCAN4 Protein Expression
    REFSEQ proteins: NP_061983.2  
    ENSEMBL proteins: 
     ENSP00000366509   ENSP00000401978  
    Reactome Protein details: Q969J2
    Human Recombinant Protein Products for ZKSCAN4: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ZKSCAN4
    OriGene Protein Over-expression Lysate for ZKSCAN4
    OriGene MassSpec for ZKSCAN4 
    OriGene Custom Protein Services for ZKSCAN4
    GenScript Custom Purified and Recombinant Proteins Services for ZKSCAN4
    Novus Biologicals ZKSCAN4 Protein
    Novus Biologicals ZKSCAN4 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZKSCAN4 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    ZKSCAN4 for ontologies           About GeneDecksing



    ZKSCAN4 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for ZKSCAN4
    OriGene Custom Antibody Services for ZKSCAN4
    GenScript Custom Superior Antibodies Services for ZKSCAN4
    Novus Biologicals ZKSCAN4 Antibodies
    Abcam antibodies for ZKSCAN4
    Cloud-Clone Corp. Antibodies for ZKSCAN4 
    ThermoFisher Antibodies for ZKSCAN4
    LSBio Antibodies in human, mouse, rat for ZKSCAN4 

    Assay Products for ZKSCAN4: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZKSCAN4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZKSCAN4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZKSCAN4 
    Cloud-Clone Corp. CLIAs for ZKSCAN4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZNF: Zinc fingers, C2H2-type

    5/6 InterPro protein domains (see all 6):
     IPR015880 Znf_C2H2-like
     IPR001909 Krueppel-associated_box
     IPR008916 Retrov_capsid_C
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q969J2

    ProtoNet protein and cluster: Q969J2

    3 Blocks protein domains:
    IPB001909 KRAB box
    IPB003309 Transcriptional regulator SCAN
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZKSC4_HUMAN, Q969J2
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 7 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain
    Similarity: Contains 1 SCAN box domain


    ZKSCAN4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZKSC4_HUMAN, Q969J2
    Function: May be involved in the transcriptional activation of MDM2 and EP300 genes

         Enzyme Numbers (IUBMB): EC 2.1.1.432 EC 4.2.1.522

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0008270zinc ion binding ----
    GO:0046872metal ion binding IEA--
         
    ZKSCAN4 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZKSCAN4:
     Increased cilium length after  

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZKSCAN4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZKSCAN4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZKSCAN4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZKSCAN4 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZKSCAN4
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ZKSCAN4
    SwitchGear 3'UTR luciferase reporter plasmidZKSCAN4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZKSCAN4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZKSCAN4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZKSCAN4
    Sirion Biotech Customized adenovirus for overexpression of ZKSCAN4

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ZKSCAN4 (see all 7)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZKSCAN4 (NM_019110)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZKSCAN4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZKSCAN4
    Sirion Biotech Customized lentivirus for stable overexpression of ZKSCAN4 
                         Customized lentivirus expression plasmids for stable overexpression of ZKSCAN4 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZKSCAN4
    Search LifeMap BioReagents cell lines for ZKSCAN4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZKSCAN4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ZKSCAN4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Generic Transcription Pathway
    Generic Transcription Pathway0.47
    Gene Expression0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2        Reactome Pathways for ZKSCAN4
        Generic Transcription Pathway
    Gene Expression



    ZKSCAN4 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZKSCAN4

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ZKSCAN4 (Q969J23 ENSP000003665094) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TERF2Q155543, ENSP000002549424I2D: score=1 STRING: ENSP00000254942
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0016032viral process ----

    ZKSCAN4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZKSCAN4 (ZKSC4)

    Search CenterWatch for drugs/clinical trials and news about ZKSCAN4 / ZKSC4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZKSCAN4 gene: 
    NM_019110.3  

    Unigene Cluster for ZKSCAN4:

    Zinc finger with KRAB and SCAN domains 4
    Hs.44720  [show with all ESTs]
    Unigene Representative Sequence: AY781778
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377294(uc003nks.1 uc011dlb.1) ENST00000423974
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZKSCAN4
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ZKSCAN4
    SwitchGear 3'UTR luciferase reporter plasmidZKSCAN4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZKSCAN4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZKSCAN4
    Clone
    Products:
         
    OriGene clones in human, mouse for ZKSCAN4 (see all 7)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZKSCAN4 (NM_019110)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZKSCAN4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZKSCAN4
    Sirion Biotech Customized lentivirus for stable overexpression of ZKSCAN4 
                         Customized lentivirus expression plasmids for stable overexpression of ZKSCAN4 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ZKSCAN4
    OriGene qSTAR qPCR primer pairs in human, mouse for ZKSCAN4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZKSCAN4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZKSCAN4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZKSCAN4

    Additional mRNA sequence: 

    AK302017.1 AK315783.1 AY781778.1 BC014031.2 

    4 DOTS entries:

    DT.309108  DT.95286179  DT.100702103  DT.102821185 

    24/57 AceView cDNA sequences (see all 57):

    CA424165 CR625010 AL040316 AW135346 BC014031 NM_019110 AW594039 T08471 
    AI251024 AI139333 BQ006541 AK056698 AA580929 AA808566 BM973187 AI638854 
    BG431384 BG614793 AL555537 BU154576 BX350505 F02809 AA218821 AI830652 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZKSCAN4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGTCTTTTA
    ZKSCAN4 Expression
    About this image


    See ZKSCAN4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZKSCAN4

    SOURCE GeneReport for Unigene cluster: Hs.44720

    UniProtKB/Swiss-Prot: ZKSC4_HUMAN, Q969J2
    Tissue specificity: Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and
    skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine

        SABiosciences Custom PCR Arrays for ZKSCAN4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ZKSCAN4
    OriGene qSTAR qPCR primer pairs in human, mouse for ZKSCAN4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZKSCAN4
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZKSCAN4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZKSCAN4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZKSCAN4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for ZKSCAN4 gene from 1/6 species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zkscan31 zinc finger with KRAB and SCAN domains 3 79.64(n)
    72.37(a)
      72739  NM_001145778.1  NP_001139250.1 


    ENSEMBL Gene Tree for ZKSCAN4 (if available)
    TreeFam Gene Tree for ZKSCAN4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZKSCAN4 gene
    ZNF4462  ZSCAN92  ZKSCAN12  ZNF3972  ZNF2322  ZSCAN302  ZNF1742  ZNF32  
    ZNF3962  ZSCAN122  ZNF3942  ZSCAN232  ZSCAN212  ZNF1652  ZSCAN162  ZKSCAN82  
    ZSCAN222  ZSCAN312  ZNF242  ZKSCAN32  ZNF182  
    18/486 SIMAP similar genes for ZKSCAN4 using alignment to 2 protein entries:     ZKSC4_HUMAN (see all proteins) (see all similar genes):
    ZKSCAN3    ZNF78L1    ZNF56    ZNF826P    HZF16    ZNF883
    ZNF    ZFP41    ZFS-6    ZNF595    ZNF345    HZF40
    HZF41    ZFS-4    ZNF180    smap-7    ZFP2    ZFS-5

    ZKSCAN4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/237 SNPs in ZKSCAN4 are shown (see all 237)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1407471001,2
    --28212150(+) ATTAAA/CATTGA 1 -- int10--------
    rs1500890461,2
    --28212248(+) TCATGG/TTAGAG 1 -- int10--------
    rs1383603371,2
    --28212296(+) TGTACA/GTGGCA 1 -- int10--------
    rs1492227741,2
    C--28212357(+) AAATTC/TAAATG 1 -- int10--------
    rs1114199011,2
    C,F--28212367(+) GGCATG/AAGTTA 1 -- int12Minor allele frequency- A:0.50CSA 4
    rs1392762601,2
    --28212478(+) AAAGAA/TGAGTA 1 -- int10--------
    rs77572151,2
    C,F,A,H--28212489(+) AAAGAC/ACTCAT 1 -- spd1 ese329Minor allele frequency- A:0.10NS NA EA WA CSA 2728
    rs134081,2
    C,F,H--28212748(-) TGAGAT/CGATGA 1 -- ut31 ese335Minor allele frequency- C:0.37MN EA NA NS WA CSA 4717
    rs1166307541,2
    C,F--28212786(+) GATGTA/GTAGTG 1 -- ut311Minor allele frequency- G:0.05WA 118
    rs2001593901,2
    C--28212933(+) CTCTGA/GTGTTG 2 H syn11Minor allele frequency- G:0.00EU 1323

    HapMap Linkage Disequilibrium report for ZKSCAN4 (28212401 - 28227011 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ZKSCAN4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv830620CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ZKSCAN4
    DNA2.0 Custom Variant and Variant Library Synthesis for ZKSCAN4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ZKSCAN4 for disorders           About MalaCards
    OMIM gene information: 611643    OMIM disorders: --


    ZKSCAN4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZKSCAN4

    Export disorders for ZKSCAN4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZKSCAN4 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ZKSCAN4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ZNF307, a novel zinc finger gene suppresses p53 and p21 pathway. (PubMed id 17910948)1, 2 Li J.... Wu X. (2007)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    6. The protein network surrounding the human telomere re peat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (2010)
    7. A RAS recruitment screen identifies ZKSCAN4 as a glucocorticoid receptor-interacting protein. (PubMed id 19008334)1 Ecker K....Helmberg A. (2009)
    8. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PubMed id 17525332)2 Matsuoka S.... Elledge S.J. (2007)
    9. Framingham Heart Study genome-wide association: results for pulmonary function measures. (PubMed id 17903307)4 Wilk J.B....O'Connor G.T. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 387032 HGNC: 13854 AceView: ZNF307 Ensembl:ENSG00000187626 euGenes: HUgn387032
    ECgene: ZKSCAN4 H-InvDB: ZKSCAN4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZKSCAN4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZKSCAN4 gene:
    Search GeneIP for patents involving ZKSCAN4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for ZKSCAN4   OriGene RNAi products in human, mouse, rat for ZKSCAN4  
     OriGene qPCR primer pairs and template standards for ZKSCAN4   OriGene Protein Over-expression Lysate for ZKSCAN4  
     OriGene MassSpec something-or-other for ZKSCAN4   OriGene clones in human, mouse for ZKSCAN4  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZKSCAN4   OriGene Purified Protein for ZKSCAN4  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZKSCAN4   OriGene Custom Protein Services for ZKSCAN4  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZKSCAN4
     QIAGEN SeqTarget long-range PCR primers for resequencing ZKSCAN4
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZKSCAN4
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZKSCAN4
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZKSCAN4
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZKSCAN4
     GenScript Custom Purified and Recombinant Proteins Services for ZKSCAN4 GenScript cDNA clones with any tag delivered in your preferred vector for ZKSCAN4
     GenScript Custom Assay Services for ZKSCAN4 GenScript Custom Superior Antibodies Services for ZKSCAN4
     GenScript Custom overexpressing Cell Line Services for ZKSCAN4 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ZKSCAN4 promoter
     Search Chromatin IP Primers for ZKSCAN4
     RT2 qPCR Primer Assay in human, mouse, rat ZKSCAN4
     Search GNC Networks for ZKSCAN4
     SABiosciences Custom PCR Arrays for ZKSCAN4
     Search Tocris compounds for ZKSCAN4 (ZKSC4)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ZKSCAN4 antibodies
     ZKSCAN4 proteins
     ZKSCAN4 lysates
     Antibodies for ZKSCAN4
     See all of Abcam's Antibodies, Kits and Proteins for ZKSCAN4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ZKSCAN4
     Antibodies for ZKSCAN4
     ELISAs for ZKSCAN4
     CLIAs for ZKSCAN4
     Search LifeMap BioReagents cell lines for ZKSCAN4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZKSCAN4
     SwitchGear 3'UTR luciferase reporter plasmids for ZKSCAN4
     SwitchGear Promoter luciferase reporter plasmids for ZKSCAN4
     ThermoFisher Antibodies for ZKSCAN4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZKSCAN4
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ZKSCAN4
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZKSCAN4
    Customized:
     lentivirus for stable overexpression of ZKSCAN4
     lentivirus expression plasmids for stable overexpression of ZKSCAN4
     adenovirus for overexpression of ZKSCAN4
     LSBio Antibodies in human, mouse, rat for ZKSCAN4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZKSCAN4 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4