Aliases for ZIC5 Gene
External Ids for ZIC5 Gene
Previous GeneCards Identifiers for ZIC5 Gene
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 2, a related family member on chromosome 13. [provided by RefSeq, Jul 2008]
GeneCards Summary for ZIC5 Gene
ZIC5 (Zic Family Member 5) is a Protein Coding gene. Diseases associated with ZIC5 include visceral heterotaxy and holoprosencephaly. Among its related pathways are Neural Crest Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZIC4.
UniProtKB/Swiss-Prot for ZIC5 Gene
Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA (By similarity).