Aliases for ZIC5 Gene
External Ids for ZIC5 Gene
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 2, a related family member on chromosome 13. [provided by RefSeq, Jul 2008]
GeneCards Summary for ZIC5 Gene
ZIC5 (Zic Family Member 5) is a Protein Coding gene. Diseases associated with ZIC5 include visceral heterotaxy and heterotaxy. Among its related pathways are Neural Crest Differentiation. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZIC4.
UniProtKB/Swiss-Prot for ZIC5 Gene
Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA (By similarity).