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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ZIC5 Gene

protein-coding GIFtS: 45
GCID: GC13M100615

Zic family member 5

(Previous names: Zic family member 5 (odd-paired homolog, Drosophila) )

Explore 13 diseases affiliated with
ZIC5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Zic Family Member 5¹ ²
Zic Family Member 5 (Odd-Paired Homolog, Drosophila)¹ ²
Zinc Finger Protein Of The Cerebellum 5² ³
Zinc Family Member 5 Protein²
Zinc Finger Protein ZIC 5²

External Ids:	HGNC: 20322¹	Entrez Gene: 85416²	Ensembl: ENSG00000139800⁷	UniProtKB: Q96T25³

Export aliases for ZIC5 gene to outside databases

Previous GC identifers: GC13M098977 GC13M095004 GC13M099454 GC13M098315 GC13M099415 GC13M081209

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ZIC5:

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important

during development, and have been associated X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is

closely linked to a gene encoding zinc finger protein of the cerebellum 2, a related family member on chromosome 13.

(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ZIC5_HUMAN, Q96T25

Function: Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate.

Binds to DNA (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000013.10 NC_018924.1 NT_009952.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ZIC5 gene promoter:
E2F-3a E2F-4 COUP-TF1 MyoD COUP HNF-4alpha2 HNF-4alpha1 COUP-TF Sox9
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZIC5 promoter sequence

Search SABiosciences Chromatin IP Primers for ZIC5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZIC5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q32.3 Ensembl cytogenetic band: 13q32.3 HGNC cytogenetic band: 13q32.2

ZIC5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZIC5 gene location

GeneLoc information about chromosome 13 GeneLoc Exon Structure

GeneLoc location for GC13M100615: view genomic region (about GC identifiers)

Start:	100,615,275 bp from pter	End:	100,624,178 bp from pter
Size:	8,904 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ZIC5_HUMAN, Q96T25 (See protein sequence)

Recommended Name: Zinc finger protein ZIC 5

Size: 663 amino acids; 68448 Da

Subcellular location: Nucleus (By similarity)

Caution: It is uncertain whether Met-1 or Met-25 is the initiator

Sequence caution: Sequence=AAK55418.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Secondary accessions: Q5VYB0

Explore the universe of human proteins at neXtProt for ZIC5: NX_Q96T25

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96T25

ZIC5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_149123.2

ENSEMBL proteins:

ENSP00000267294

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	Uscn Proteins for ZIC5

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

ZIC5 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZIC5 for domains About GeneDecksing

3 InterPro domains/families:

IPR015880 Znf_C2H2-like

IPR013087 Znf_C2H2/integrase_DNA-bd

IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q96T25

ProtoNet protein and cluster: Q96T25

UniProtKB/Swiss-Prot: ZIC5_HUMAN, Q96T25

Similarity: Belongs to the GLI C2H2-type zinc-finger protein family

Similarity: Contains 4 C2H2-type zinc fingers

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ZIC5_HUMAN, Q96T25

Function: Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate.

Binds to DNA (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: ZIC5 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZIC5
		8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate ZIC5 (see all 31):
		hsa-miR-323-3p hsa-miR-21* hsa-miR-4272 hsa-miR-29c hsa-miR-29a hsa-miR-767-5p hsa-miR-301a hsa-miR-449a

		SwitchGear 3'UTR luciferase reporter plasmid: ZIC5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZIC5 (see all 7) OriGene shRNA RFP: ZIC5 OriGene siRNA: ZIC5
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZIC5

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0008270	zinc ion binding	IEA	--

ZIC5 for ontologies           About GeneDecksing

Animal Models:
     Mouse knock-out Zic5^tm1Jaru for ZIC5
     8 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Zic5):

behavior/neurological	craniofacial	embryogenesis	growth/size	mortality/aging
nervous system	skeleton	vision/eye

ZIC5 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Neural Crest Differentiation

Neural Crest Differentiation

1.00

1 BioSystems Pathway for ZIC5

Neural Crest Differentiation

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ZIC5

1 Interacting protein for ZIC5 (Q96T25²) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
--	P31016²	MINT-8106021

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001843	neural tube closure	IEA	--
GO:0030154	cell differentiation	IEA	--
GO:0030900	forebrain development	IEA	--

ZIC5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZIC5
Search CenterWatch for drugs/clinical trials and news about ZIC5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ZIC5 gene:

NM_033132.3

Unigene Cluster for ZIC5:

Zic family member 5

Hs.508570 [show with all ESTs]

Unigene Representative Sequence: NM_033132

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000267294(uc001vom.1)

miRNA Products:		OriGene 3'-UTR Clone: ZIC5 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZIC5
		8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate ZIC5 (see all 31):
		hsa-miR-323-3p hsa-miR-21* hsa-miR-4272 hsa-miR-29c hsa-miR-29a hsa-miR-767-5p hsa-miR-301a hsa-miR-449a

		SwitchGear 3'UTR luciferase reporter plasmid: ZIC5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZIC5 (see all 7) OriGene shRNA RFP: ZIC5 OriGene siRNA: ZIC5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZIC5

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZIC5 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZIC5 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZIC5 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZIC5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZIC5

Additional cDNA sequence: AF378304.1

3 DOTS entries:

DT.405334 DT.102835927 DT.40211565

6 AceView cDNA sequences:

BF057226 BE552258 NM_033132 AI699626 AF378304 BF511233

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZIC5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CATAGGTTAA

About this image

ZIC5 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Line H9 (WA09) (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ZIC5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZIC5

SOURCE GeneReport for Unigene cluster: Hs.508570

SABiosciences Custom PCR Arrays for ZIC5

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZIC5 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZIC5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZIC5

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZIC5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ZIC5 gene from 8/24 species (see all 24) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ZIC4⁶	Uncharacterized protein	63(a)	possible ortholog	9(12989929-13002726)
lizard (Anolis carolinensis)	Reptilia	ZIC5⁶	--	84(a)	1 ↔ 1	3(99260063-99269560)
African clawed frog (Xenopus laevis)	Amphibia	zic5-A²	Zic family member 5	80.13(n)		AB034983.1
zebrafish (Danio rerio)	Actinopterygii	Dr.27091²	Danio rerio zinc finger protein Zic5 (zic5) mRNA, complete more	80.04(n)		AY326458.1
fruit fly (Drosophila melanogaster)	Insecta	opa³	midgut development specific RNA polymerase II more	62(a) (best of 2)		3 82E1 --
worm (Caenorhabditis elegans)	Secernentea	ref-2⁶	REgulator of Fusion family member (ref-2)	31(a)	possible ortholog	X(7744188-7749959)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT4G06634⁶	uncharacterized zinc finger protein	16(a)	1 → many	4(3764289-3766578)
rice (Oryza sativa)	Liliopsida	NM_188290.1²	--	72.5(n)		NM_188290.1

ENSEMBL Gene Tree for ZIC5 (if available)
TreeFam Gene Tree for ZIC5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ZIC5 gene

ZNF76² GLI1² ZIC2² YY1² ZIC1² GLIS2² GLI2² ZNF143²

GLI3² YY2² MTF1² ZIC3² ZNF410² ZFP42² GLIS1² ZIC4²

GLIS3²

8 SIMAP similar genes for ZIC5 using alignment to 1 protein entry: ZIC5_HUMAN:

GLIS3 ZNF ZIC4 ZNF323 ZNF844 ZIC1

ZIC2 ZNF702P

ZIC5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 13 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs191926146^1,2		--	100614911(+)	`CTCACC/TGTCCC`	1	--	int¹		0	--	--	--	--
rs182686257^1,2		--	100614927(+)	`CCACAC/TTTTCT`	1	--	int¹		0	--	--	--	--
rs147700520^1,2		--	100615052(+)	`AGTAAC/GCCAAA`	1	--	int¹		0	--	--	--	--
rs142829906^1,2		--	100615110(+)	`ATATC-/TGTGTTT`	1	--	int¹		0	--	--	--	--
rs187016340^1,2		--	100615111(+)	`TATCTA/GTGTTT`	1	--	int¹		0	--	--	--	--
rs118007166^1,2		--	100615179(+)	`TGGGGA/GGAGGC`	1	--	int¹		1		NA	120
rs3742253^1,2	C,F,A,H,	--	100615196(-)	`GGTCTC/GTTGAT`	1	--	int¹		29		EA NS NA CSA WA	3354
rs114278857^1,2	F,	--	100615221(+)	`ACTCCA/CTTAGC`	1	--	int¹		1		WA	118
rs16957100^1,2	C,F,H,	--	100615239(+)	`TCTATT/GTGTAT`	1	--	int¹		14		NA NS EA WA	1526
rs146744635^1,2		--	100615349(+)	`TACAC-/ATTTTT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZIC5 (100615275 - 100624178 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZIC5: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZIC5

DNA2.0 Custom Variant and Variant Library Synthesis for ZIC5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ZIC5 for disorders About GeneDecksing

13 diseases for ZIC5: About MalaCards

dandy-walker malformation holoprosencephaly alcohol-related birth defect alcohol-related neurodevelopmental disorder

visceral heterotaxy partial fetal alcohol syndrome fetal alcohol syndrome birth defects

heterotaxy alcoholism coloboma meningioma

cerebritis

1 disease from the University of Copenhagen DISEASES database for ZIC5:

Holoprosencephaly

Export disorders for ZIC5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ZIC5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZIC5)

Utopia: connect your pdf to the dynamic
world of online information

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Expression of ZIC family genes in meningiomas and oth er brain tumors. (PubMed id 20199689)¹ Aruga J....Yokota N. (2010)
Description of the smallest critical region for Dandy -Walker malformation in chromosome 13 in a girl with a cryptic deletion related to t(6;13)(q23;q32). (PubMed id 20683983)¹ Mademont-Soler I....SA!nchez A. (2010)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)² Dunham A.... Ross M.T. (2004)
Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family. (PubMed id 15465018)¹ Ishiguro A....Aruga J. (2004)
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)¹ Brandenberger R.... Stanton L.W. (2004)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)
A new murine zinc finger gene, Opr. (PubMed id 11044622)¹ Furushima K....Aizawa S. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 85416	HGNC: 20322	AceView: ZIC5	Ensembl:ENSG00000139800	euGenes: HUgn85416
ECgene: ZIC5	H-InvDB: ZIC5

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ZIC5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ZIC5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for ZIC5 gene:
Search GeneIP for patents involving ZIC5

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZIC5
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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes ZIC5 gene at Home site.

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ZIC5 Gene

Zic family member 5

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ZIC5 Gene

Zic family member 5

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Protein Domains /Familiesfor ZIC5 gene

Functionfor ZIC5 gene

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