Aliases for ZHX2 Gene
Aliases for ZHX2 Gene
External Ids for ZHX2 Gene
- HGNC: 18513
- Entrez Gene: 22882
- Ensembl: ENSG00000178764
- OMIM: 609185
- UniProtKB: Q9Y6X8
Previous GeneCards Identifiers for ZHX2 Gene
- GC08P123462
- GC08P123750
- GC08P123863
- GC08P123793
- GC08P119119
Summaries for ZHX2 Gene
-
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008]
GeneCards Summary for ZHX2 Gene
ZHX2 (Zinc Fingers And Homeoboxes 2) is a Protein Coding gene. Among its related pathways are Hypothetical Network for Drug Addiction. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and identical protein binding. An important paralog of this gene is ZHX1.
UniProtKB/Swiss-Prot for ZHX2 Gene
-
Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZHX2 Gene
Genomics for ZHX2 Gene
Regulatory Elements for ZHX2 Gene
Enhancers for ZHX2 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around ZHX2 on UCSC Golden Path with GeneCards custom track
Promoters for ZHX2 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around ZHX2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ZHX2 gene promoter:
Regulatory Element Products
Genomic Location for ZHX2 Gene
- Chromosome:
- 8
- Start:
- 122,781,349 bp from pter
- End:
- 122,974,515 bp from pter
- Size:
- 193,167 bases
- Orientation:
- Plus strand
Genomic View for ZHX2 Gene
Genes around ZHX2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q24.13 by Ensembl
- 8q24.13 by Entrez Gene
- 8q24.13 by HGNC
ZHX2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZHX2 Gene
Proteins for ZHX2 Gene
-
Protein details for ZHX2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y6X8-ZHX2_HUMAN
- Recommended name:
- Zinc fingers and homeoboxes protein 2
- Protein Accession:
- Q9Y6X8
Protein attributes for ZHX2 Gene
- Size:
- 837 amino acids
- Molecular mass:
- 92307 Da
- Quaternary structure:
-
- Forms a homodimer (via homeobox domain). Forms a heterodimer with ZHX1 (via HD1 domain). Forms a heterodimer with ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts (via homeobox domain) with NFYA (via N-terminus).
- SequenceCaution:
-
- Sequence=BAA74877.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for ZHX2 Gene
Post-translational modifications for ZHX2 Gene
Other Protein References for ZHX2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ZHX2
- Abcam antibodies for ZHX2
- Invitrogen Antibodies for ZHX2
- antibodies-online Antibodies for ZHX2: See all 100
- GeneTex ZHX2 antibody for ZHX2
-
Santa Cruz Biotechnology (SCBT) Antibodies for ZHX2
Protein Products
-
OriGene Purified Proteins for ZHX2
- Search Origene for MassSpec and Protein Over-expression Lysates for ZHX2
- Origene Custom Protein Services for ZHX2
- antibodies-online Proteins for ZHX2: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ZHX2
- Abcam proteins for ZHX2
Assay Products
- antibodies-online Kits for ZHX2: See all 1
No data available for DME Specific Peptides for ZHX2 Gene
Domains & Families for ZHX2 Gene
Gene Families for ZHX2 Gene
Protein Domains for ZHX2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZHX2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9Y6X8UniProtKB/Swiss-Prot:
ZHX2_HUMAN :- Contains 4 homeobox DNA-binding domains.
- Belongs to the ZHX family.
- Contains 2 C2H2-type zinc fingers.
- Domain:
-
- Contains 4 homeobox DNA-binding domains.
- Family:
-
- Belongs to the ZHX family.
- Similarity:
-
- Contains 2 C2H2-type zinc fingers.
Function for ZHX2 Gene
Molecular function for ZHX2 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003714 | transcription corepressor activity | IDA | 12741956 |
| GO:0005515 | protein binding | IEA,IPI | 12741956 |
| GO:0042802 | identical protein binding | IPI | 12741956 |
| GO:0042803 | protein homodimerization activity | IDA | 12741956 |
Phenotypes for ZHX2 Gene
- MGI mutant phenotypes for ZHX2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ZHX2:
-
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased viability in esophageal squamous lineage
- Decreased shRNA abundance (Z-score < -2)
- Dynamic nuclei (hole, folded or small irregular)
- Effect on mitosis
- Increased shRNA abundance (Z-score > 2)
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for ZHX2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
- Search ViGene Biosciences for ZHX2
CRISPR Products
-
OriGene CRISPR knockouts for ZHX2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZHX2
- GenScript: Design CRISPR guide RNA sequences for ZHX2
miRNA for ZHX2 Gene
- miRTarBase miRNAs that target ZHX2
miRNA Products
- Search ViGene Biosciences for ZHX2
Inhibitory RNA Products
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for ZHX2
- Browse OriGene Inhibitory RNA Products For ZHX2
-
ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
Clone Products
- OriGene clones in human for ZHX2
- OriGene ORF clones in human,mouse,rat for ZHX2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for ZHX2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ZHX2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZHX2 Gene
Localization for ZHX2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZHX2 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 5 |
| cytosol | 2 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | -- |
Pathways & Interactions for ZHX2 Gene
More details on SuperPathways for ZHX2| Superpath | Contained pathways | |
|---|---|---|
| 1 | Hypothetical Network for Drug Addiction |
Pathways by source for ZHX2 Gene
1 BioSystems pathway for ZHX2 Gene
Interacting Proteins for ZHX2 Gene
Selected Interacting proteins:
Q9Y6X8-ZHX2_HUMAN
ENSP00000314709
for ZHX2 Gene via
MINT
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006402 | mRNA catabolic process | IEA | -- |
| GO:0035019 | somatic stem cell population maintenance | IEA | -- |
| GO:0045665 | negative regulation of neuron differentiation | IEA | -- |
No data available for SIGNOR curated interactions for ZHX2 Gene
Drugs & Compounds for ZHX2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| regorafenib | Approved | Pharma | inhibitor | Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1, Kinase Inhibitors, Vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) inhibitors | 0 | |
| Sorafenib | Approved, Investigational | Pharma | inhibitors, inhibitor | Raf kinases and tyrosine kinases inhibitor, RAF, VEGFR2, and PDGFR-beta inhibitors, Kinase Inhibitors, Vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) inhibitors | 677 |
Transcripts for ZHX2 Gene
mRNA/cDNA for ZHX2 Gene
- (5) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (121) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ZHX2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ZHX2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZHX2
- GenScript: Design CRISPR guide RNA sequences for ZHX2
miRNA Products
- Search ViGene Biosciences for ZHX2
Inhibitory RNA Products
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for ZHX2
- Browse OriGene Inhibitory RNA Products For ZHX2
-
ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
Clone Products
- OriGene clones in human for ZHX2
- OriGene ORF clones in human,mouse,rat for ZHX2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||
| SP3: |
Expression for ZHX2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Liver (Hepatobiliary System)
- Mature Hepatocytes Liver Lobule
- Hepatocytes Liver Lobule
- Brain (Nervous System)
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
- Ovary (Reproductive System)
This gene is overexpressed in Bone marrow mesenchymal stem cell (54.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZHX2 Gene
SOURCE GeneReport for Unigene cluster for ZHX2 Gene Hs.377090
mRNA Expression by UniProt/SwissProt for ZHX2 Gene
Q9Y6X8-ZHX2_HUMAN
Tissue specificity:
Ubiquitously expressed. Expressed in podocytes.
Primer Products
-
OriGene qPCR primer pairs for ZHX2
-
OriGene qPCR primer pairs and template standards for ZHX2
No data available for mRNA differential expression in normal tissues and Protein tissue co-expression partners for ZHX2 Gene
Orthologs for ZHX2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | ZHX2 35 |
|
||
| ZHX2 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | ZHX2 35 |
|
||
| ZHX2 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Zhx2 35 |
|
||
| Zhx2 16 |
|
||||
| Zhx2 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | ZHX2 35 |
|
||
| ZHX2 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Zhx2 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ZHX2 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ZHX2 35 |
|
||
| ZHX2 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | ZHX2 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.1051 35 |
|
||
| zhx2 35 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.13932 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | zhx2 35 |
|
||
| zhx2 36 |
|
OneToOne |
- Species with no ortholog for ZHX2:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ZHX2 Gene
(2) SIMAP similar genes for ZHX2 Gene using alignment to 2 proteins:
Variants for ZHX2 Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs9649951 | - | 122,952,579(+) | CAAAG(A/G)TGACG | reference, missense | |
| rs35319449 | - | 122,953,456(+) | TGCAA(A/G)AACCC | reference, missense | |
| rs3802264 | - | 122,953,845(+) | GGGAC(A/G)GCCAG | reference, missense | |
| rs2084047 | -- | 122,832,700(+) | gaaaa(C/G)agaga | intron-variant | |
| rs2120911 | -- | 122,805,762(+) | GCCCA(A/G)CAGTT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2737525 | CNV | Deletion | 23290073 |
Residual Variation Intolerance Score:
69.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.93;
79.74% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZHX2 Gene
Disorders for ZHX2 Gene
Relevant External Links for ZHX2
No disorders were found for ZHX2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZHX2 Gene
Publications for ZHX2 Gene
- Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor. (PMID: 12741956) Kawata H. … Miyamoto K. (Biochem. J. 2003) 2 3 4 67
- ZHX2 is a repressor of alpha-fetoprotein expression in human hepatoma cell lines. (PMID: 18194454) Shen H. … Ma C. (J. Cell. Mol. Med. 2008) 3 23
- The mouse zinc-fingers and homeoboxes (ZHX) family; ZHX2 forms a heterodimer with ZHX3. (PMID: 14659886) Kawata H. … Miyamoto K. (Gene 2003) 3 23
- Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10048485) Nagase T. … Ohara O. (DNA Res. 1998) 2 3
- ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA. (PMID: 25473899) Ma H. … Ma C. (Oncotarget 2015) 3
Products for ZHX2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ZHX2
- Search Origene for MassSpec and Protein Over-expression Lysates for ZHX2
- Origene Custom Protein Services for ZHX2
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for ZHX2
- Browse OriGene Inhibitory RNA Products For ZHX2
- OriGene qPCR primer pairs for ZHX2
- OriGene qPCR primer pairs and template standards for ZHX2
- OriGene CRISPR knockouts for ZHX2
- OriGene clones in human for ZHX2
- OriGene ORF clones in human,mouse,rat for ZHX2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for ZHX2
- GenScript Custom Assay Services for ZHX2
- GenScript Custom overexpressing Cell Line Services for ZHX2
- GenScript: Design CRISPR guide RNA sequences for ZHX2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ZHX2
- Novus Biologicals Antibodies for ZHX2
- Novus Biologicals proteins and lysates for ZHX2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for ZHX2
- Abcam proteins for ZHX2
- Search for Assays for ZHX2 at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- antibodies-online Antibodies for ZHX2: See all 100
- antibodies-online Kits for ZHX2: See all 1
- antibodies-online Proteins for ZHX2: See all 4
- Search antibodies-online for peptides
- GeneTex ZHX2 antibody for ZHX2
- Search GeneTex for Proteins for ZHX2
- ViGene Biosciences adenoviral particle packaged cDNA for ZHX2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ZHX2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ZHX2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
- Search ViGene Biosciences for ZHX2
- Search ViGene Biosciences for ZHX2
- Santa Cruz Biotechnology (SCBT) Antibodies for ZHX2
- Search Santa Cruz Biotechnology (SCBT) for ZHX2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ZHX2
Sources for ZHX2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon