Aliases for ZHX2 Gene
Aliases for ZHX2 Gene
External Ids for ZHX2 Gene
- HGNC: 18513
- Entrez Gene: 22882
- Ensembl: ENSG00000178764
- OMIM: 609185
- UniProtKB: Q9Y6X8
Previous GeneCards Identifiers for ZHX2 Gene
- GC08P123462
- GC08P123750
- GC08P123863
- GC08P123793
- GC08P119119
Summaries for ZHX2 Gene
-
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008]
GeneCards Summary for ZHX2 Gene
ZHX2 (Zinc Fingers And Homeoboxes 2) is a Protein Coding gene. Diseases associated with ZHX2 include Smallpox and Cryptococcosis. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and identical protein binding. An important paralog of this gene is ZHX1.
UniProtKB/Swiss-Prot for ZHX2 Gene
-
Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZHX2 Gene
Genomics for ZHX2 Gene
Regulatory Elements for ZHX2 Gene
Enhancers for ZHX2 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH08G122779 | 1.7 | FANTOM5 ENCODE dbSUPER | 15.4 | +0.6 | 584 | 4.4 | HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 | ZHX2 DERL1 TBC1D31 C8orf76 PIR52073 |
| GH08G122798 | 1.5 | FANTOM5 Ensembl ENCODE dbSUPER | 11.5 | +17.8 | 17832 | 2.1 | HDGF ZNF687 MTA2 BHLHE40 EBF1 DPF2 NONO TARDBP NFYB NBN | ZHX2 C8orf76 PIR52073 ENSG00000253372 |
| GH08G122830 | 1.3 | Ensembl ENCODE dbSUPER | 13 | +48.9 | 48852 | 0.4 | CBX3 ZNF766 CBX5 CAVIN1 ZBTB11 HDAC8 ZNF592 MEF2D CREB3 ZNF589 | ZHX2 ENSG00000253372 GC08P122905 |
| GH08G122828 | 1.4 | Ensembl ENCODE dbSUPER | 11.8 | +47.1 | 47093 | 0.8 | HDGF ATF1 CREB3L1 ARNT TCF12 GATA2 FOS KDM4B NCOA1 ZNF592 | ZHX2 ENSG00000253607 ENSG00000253372 GC08P122905 |
| GH08G122784 | 1.8 | FANTOM5 Ensembl ENCODE dbSUPER | 8.1 | +5.8 | 5773 | 5.8 | HDGF ATF1 PKNOX1 FOXA2 WRNIP1 SIN3A YBX1 ZBTB7B ETS1 ZNF143 | ZHX2 PIR52073 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ZHX2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ZHX2 gene promoter:
Regulatory Element Products
Genomic Location for ZHX2 Gene
- Chromosome:
- 8
- Start:
- 122,781,349 bp from pter
- End:
- 122,974,515 bp from pter
- Size:
- 193,167 bases
- Orientation:
- Plus strand
Genomic View for ZHX2 Gene
Genes around ZHX2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q24.13 by Ensembl
- 8q24.13 by Entrez Gene
- 8q24.13 by HGNC
ZHX2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZHX2 Gene
Proteins for ZHX2 Gene
-
Protein details for ZHX2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y6X8-ZHX2_HUMAN
- Recommended name:
- Zinc fingers and homeoboxes protein 2
- Protein Accession:
- Q9Y6X8
Protein attributes for ZHX2 Gene
- Size:
- 837 amino acids
- Molecular mass:
- 92307 Da
- Quaternary structure:
-
- Forms a homodimer (via homeobox domain). Forms a heterodimer with ZHX1 (via HD1 domain). Forms a heterodimer with ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts (via homeobox domain) with NFYA (via N-terminus).
- SequenceCaution:
-
- Sequence=BAA74877.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for ZHX2 Gene
Post-translational modifications for ZHX2 Gene
Other Protein References for ZHX2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ZHX2
-
Abcam antibodies for ZHX2
- Invitrogen Antibodies for ZHX2
- antibodies-online Antibodies for ZHX2: See all 100
- GeneTex ZHX2 antibody for ZHX2
-
Santa Cruz Biotechnology (SCBT) Antibodies for ZHX2
Protein Products
-
OriGene Purified Proteins for ZHX2
- Search Origene for MassSpec and Protein Over-expression Lysates for ZHX2
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- antibodies-online Proteins for ZHX2: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ZHX2
-
Abcam proteins for ZHX2
Assay Products
- antibodies-online Kits for ZHX2: See all 1
No data available for DME Specific Peptides for ZHX2 Gene
Domains & Families for ZHX2 Gene
Gene Families for ZHX2 Gene
Protein Domains for ZHX2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZHX2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9Y6X8- Family:
-
- Belongs to the ZHX family.
Function for ZHX2 Gene
Molecular function for ZHX2 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | transcription factor activity, sequence-specific DNA binding | IDA | 12741956 |
| GO:0003714 | transcription corepressor activity | IDA | 12741956 |
| GO:0005515 | protein binding | IPI | 12741956 |
| GO:0042802 | identical protein binding | IPI | 12741956 |
Phenotypes for ZHX2 Gene
- MGI mutant phenotypes for ZHX2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ZHX2:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- shRNA abundance <= 50%
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased viability in esophageal squamous lineage
- Decreased shRNA abundance (Z-score < -2)
- Dynamic nuclei (hole, folded or small irregular)
- Effect on mitosis
- Increased shRNA abundance (Z-score > 2)
- Increased virus production
Animal Model Products
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- Cyagen custom Knockout/knockin (KOKI) mouse models for ZHX2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ZHX2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
- Search ViGene Biosciences for ZHX2
CRISPR Products
-
OriGene CRISPR knockouts for ZHX2
-
Applied Biological Materials CRISPR for ZHX2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZHX2
- GenScript: Design CRISPR guide RNA sequences for ZHX2
miRNA for ZHX2 Gene
- miRTarBase miRNAs that target ZHX2
miRNA Products
- Search ViGene Biosciences for ZHX2
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for ZHX2
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-
ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
Clone Products
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- VectorBuilder custom plasmid, inducible vectors for ZHX2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZHX2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ZHX2
-
ViGene Biosciences adenoviral particle packaged cDNA for ZHX2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ZHX2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZHX2 Gene
Localization for ZHX2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZHX2 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 2 |
| cytosol | 2 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IDA | 12741956 |
Pathways & Interactions for ZHX2 Gene
No Data Available
Interacting Proteins for ZHX2 Gene
Selected Interacting proteins:
Q9Y6X8-ZHX2_HUMAN
ENSP00000314709
for ZHX2 Gene via
IID
STRING
UniProtKB
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | IDA | 12741956 |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription from RNA polymerase II promoter | IEA | -- |
| GO:0006402 | mRNA catabolic process | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for ZHX2 Gene
Drugs & Compounds for ZHX2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| regorafenib | Approved | Pharma | inhibitor | Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1, Kinase Inhibitors, Vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) inhibitors | 0 | |
| Sorafenib | Approved, Investigational | Pharma | inhibitors, inhibitor | Raf kinases and tyrosine kinases inhibitor, RAF, VEGFR2, and PDGFR-beta inhibitors, Kinase Inhibitors, Vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) inhibitors | 700 |
Transcripts for ZHX2 Gene
mRNA/cDNA for ZHX2 Gene
- (5) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (121) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ZHX2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ZHX2
-
Applied Biological Materials CRISPR for ZHX2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZHX2
- GenScript: Design CRISPR guide RNA sequences for ZHX2
miRNA Products
- Search ViGene Biosciences for ZHX2
Inhibitory RNA Products
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-
ViGene Biosciences ready-to-package AAV shRNAs for ZHX2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ZHX2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZHX2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||
| SP3: |
Expression for ZHX2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Liver (Hepatobiliary System)
- Mature Hepatocytes Liver Lobule
- Hepatocytes Liver Lobule
- Brain (Nervous System)
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
- Ovary (Reproductive System)
This gene is overexpressed in Bone marrow mesenchymal stem cell (54.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZHX2 Gene
NURSA nuclear receptor signaling pathways regulating expression of ZHX2 Gene:
ZHX2SOURCE GeneReport for Unigene cluster for ZHX2 Gene:
Hs.377090mRNA Expression by UniProt/SwissProt for ZHX2 Gene:
Q9Y6X8-ZHX2_HUMAN
Tissue specificity:
Ubiquitously expressed. Expressed in podocytes.
Evidence on tissue expression from TISSUES for ZHX2 Gene
- Liver(4.4)
- Nervous system(4.3)
- Kidney(4.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for ZHX2
-
OriGene qPCR primer pairs for ZHX2
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZHX2 Gene
Orthologs for ZHX2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZHX2 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ZHX2 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | ZHX2 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Zhx2 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Zhx2 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ZHX2 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ZHX2 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ZHX2 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | zhx2 34 |
|
||
| Str.1051 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.13932 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | zhx2 34 35 |
|
- Species where no ortholog for ZHX2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ZHX2 Gene
Variants for ZHX2 Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs138450443 | Uncertain significance | 122,953,192(+) | GGATC(A/G)GCTAA | reference, missense | |
| rs1000004112 | -- | 122,939,530(+) | AACCC(A/G)TGAGT | intron-variant | |
| rs1000027319 | -- | 122,846,295(+) | GCAAA(C/G)AGTCA | intron-variant | |
| rs1000035143 | -- | 122,939,291(+) | ACCTC(A/G)AAGGC | intron-variant | |
| rs1000058693 | -- | 122,970,400(+) | CGGAT(-/G)GGGGG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2737525 | CNV | deletion | 23290073 |
| esv3544137 | CNV | deletion | 23714750 |
| esv3572972 | CNV | loss | 25503493 |
| nsv1032827 | CNV | gain | 25217958 |
| nsv1150054 | CNV | insertion | 26484159 |
Residual Variation Intolerance Score:
69.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.93;
79.74% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ZHX2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZHX2 Gene
Disorders for ZHX2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| smallpox |
|
|
| cryptococcosis |
|
|
Search ZHX2 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for ZHX2
No data available for UniProtKB/Swiss-Prot and Genatlas for ZHX2 Gene
Publications for ZHX2 Gene
- Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor. (PMID: 12741956) Kawata H. … Miyamoto K. (Biochem. J. 2003) 2 3 4 64
- Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10048485) Nagase T. … Ohara O. (DNA Res. 1998) 2 3 4 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. (PMID: 20080650) Xu J. … Isaacs W.B. (Proc. Natl. Acad. Sci. U.S.A. 2010) 3 46 64
- Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G. … Wijmenga C. (Gut 2009) 3 46 64
Products for ZHX2 Gene
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- antibodies-online Antibodies for ZHX2: See all 100
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- GeneTex ZHX2 antibody for ZHX2
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- ViGene Biosciences adenoviral particle packaged cDNA for ZHX2 gene
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- Santa Cruz Biotechnology (SCBT) Antibodies for ZHX2
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- Santa Cruz Biotechnology (SCBT) CRISPR for ZHX2
- Horizon Cell Lines for ZHX2
- Cyagen custom Knockout/knockin (KOKI) mouse models for ZHX2
- VectorBuilder custom plasmid, inducible vectors for ZHX2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZHX2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ZHX2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus Biologicals
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