Aliases for ZHX2 Gene
External Ids for ZHX2 Gene
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008]
GeneCards Summary for ZHX2 Gene
ZHX2 (Zinc Fingers And Homeoboxes 2) is a Protein Coding gene. Among its related pathways are Hypothetical Network for Drug Addiction. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is ZHX1.
UniProtKB/Swiss-Prot for ZHX2 Gene
Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.