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Aliases for ZHX1-C8orf76 Gene

Aliases for ZHX1-C8orf76 Gene

  • ZHX1-C8orf76 Readthrough 2 3
  • ZHX1-C8orf76 Readthrough Transcript Protein 4
  • C8orf76 4

External Ids for ZHX1-C8orf76 Gene

Previous GeneCards Identifiers for ZHX1-C8orf76 Gene

  • GC08M124239

Summaries for ZHX1-C8orf76 Gene

Entrez Gene Summary for ZHX1-C8orf76 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring zinc fingers and homeoboxes 1 (ZHX1) and chromosome 8 open reading frame 76 (C8orf76) genes. The read-through transcript encodes a protein that shares sequence identity with the downstream gene, but it has a distinct N-terminus encoded by exon structure from the upstream gene. [provided by RefSeq, Feb 2011]

GeneCards Summary for ZHX1-C8orf76 Gene

ZHX1-C8orf76 (ZHX1-C8orf76 Readthrough) is a Protein Coding gene. An important paralog of this gene is C8orf76.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZHX1-C8orf76 Gene

Genomics for ZHX1-C8orf76 Gene

Genomic Location for ZHX1-C8orf76 Gene

Start:
123,226,189 bp from pter
End:
123,274,487 bp from pter
Size:
48,299 bases
Orientation:
Minus strand

Genomic View for ZHX1-C8orf76 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZHX1-C8orf76 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZHX1-C8orf76 Gene

No data available for Regulatory Elements for ZHX1-C8orf76 Gene

Proteins for ZHX1-C8orf76 Gene

  • Protein details for ZHX1-C8orf76 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96EF9-ZHX1R_HUMAN
    Recommended name:
    Zinc fingers and homeoboxes protein 1, isoform 2
    Protein Accession:
    Q96EF9
    Secondary Accessions:

    Protein attributes for ZHX1-C8orf76 Gene

    Size:
    292 amino acids
    Molecular mass:
    33285 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZHX1-C8orf76 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZHX1-C8orf76 Gene

Proteomics data for ZHX1-C8orf76 Gene at MOPED

Post-translational modifications for ZHX1-C8orf76 Gene

Other Protein References for ZHX1-C8orf76 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZHX1-C8orf76 Gene

Domains for ZHX1-C8orf76 Gene

Protein Domains for ZHX1-C8orf76 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZHX1-C8orf76: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ZHX1-C8orf76 Gene

Function for ZHX1-C8orf76 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZHX1-C8orf76 Gene

Localization for ZHX1-C8orf76 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZHX1-C8orf76 Gene

Pathways for ZHX1-C8orf76 Gene

SuperPathways for ZHX1-C8orf76 Gene

No Data Available

Interacting Proteins for ZHX1-C8orf76 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000349593%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000349593 for ZHX1-C8orf76 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for ZHX1-C8orf76 Gene

None

No data available for Pathways by source for ZHX1-C8orf76 Gene

Transcripts for ZHX1-C8orf76 Gene

mRNA/cDNA for ZHX1-C8orf76 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ZHX1-C8orf76 Gene

No ASD Table

Relevant External Links for ZHX1-C8orf76 Gene

GeneLoc Exon Structure for
ZHX1-C8orf76
ECgene alternative splicing isoforms for
ZHX1-C8orf76

Expression for ZHX1-C8orf76 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZHX1-C8orf76 Gene

Orthologs for ZHX1-C8orf76 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZHX1-C8orf76 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 63 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 81 (a)
OneToMany
mouse
(Mus musculus)
Mammalia 9130401M01Rik 36
  • 50 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 50 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 40 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 33 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 40 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii C16H8orf76 36
  • 26 (a)
OneToMany
Species with no ortholog for ZHX1-C8orf76:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZHX1-C8orf76 Gene

ENSEMBL:
Gene Tree for ZHX1-C8orf76 (if available)
TreeFam:
Gene Tree for ZHX1-C8orf76 (if available)

Paralogs for ZHX1-C8orf76 Gene

Paralogs for ZHX1-C8orf76 Gene

Selected SIMAP similar genes for ZHX1-C8orf76 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZHX1-C8orf76: view

Variants for ZHX1-C8orf76 Gene

Sequence variations from dbSNP and Humsavar for ZHX1-C8orf76 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs10107523 -- 123,244,036(+) AGGGT(A/C)ATGTC intron-variant
rs13261992 -- 123,247,191(+) agttc(A/C)tcagg intron-variant
rs13270372 -- 123,247,628(+) cctcc(A/C)tggta intron-variant
rs34293410 -- 123,246,500(+) TATGG(-/AC)ACACA intron-variant
rs55905385 -- 123,245,870(+) AATTC(C/G)ACCTC intron-variant

Relevant External Links for ZHX1-C8orf76 Gene

HapMap Linkage Disequilibrium report
ZHX1-C8orf76

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZHX1-C8orf76 Gene

Disorders for ZHX1-C8orf76 Gene

No disorders were found for ZHX1-C8orf76 Gene.

No data available for UniProtKB/Swiss-Prot for ZHX1-C8orf76 Gene

Publications for ZHX1-C8orf76 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3
  3. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for ZHX1-C8orf76 Gene

Sources for ZHX1-C8orf76 Gene

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