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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZGPAT Gene

protein-coding   GIFtS: 52
GCID: GC20P062338

Zinc Finger, CCCH-Type With G Patch Domain

(Previous name: KIAA1847)
(Previous symbol: KIAA1847)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger, CCCH-Type With G Patch Domain1 2     GPATCH62 3
KIAA18471 2 3     ZC3H92 3
G Patch Domain-Containing Protein 62 3     ZC3HDC92 3
Zinc Finger And G Patch Domain-Containing Protein2 3     ZIP2 3
Zinc Finger CCCH Domain-Containing Protein 92 3     Zinc Finger CCCH-Type With G Patch Domain-Containing Protein2
GPATC62 3     

External Ids:    HGNC: 159481   Entrez Gene: 846192   Ensembl: ENSG000001971147   UniProtKB: Q8N5A53   

Export aliases for ZGPAT gene to outside databases

Previous GC identifers: GC20P061810 GC20P059071


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZGPAT Gene: 
ZGPAT (zinc finger, CCCH-type with G patch domain) is a protein-coding gene. Diseases associated with ZGPAT include crohn's disease, and inflammatory bowel disease. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity.

UniProtKB/Swiss-Prot: ZGPAT_HUMAN, Q8N5A5
Function: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses
transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates
expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes
of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis

Gene Wiki entry for ZGPAT Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NT_011333.6  NC_018931.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZGPAT gene promoter:
         STAT5B   AREB6   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZGPAT promoter sequence
   Search SABiosciences Chromatin IP Primers for ZGPAT

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZGPAT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.3   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.3

ZGPAT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZGPAT gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P062338:  view genomic region     (about GC identifiers)

Start:
62,338,794 bp from pter      End:
62,370,456 bp from pter
Size:
31,663 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZGPAT_HUMAN, Q8N5A5 (See protein sequence)
Recommended Name: Zinc finger CCCH-type with G patch domain-containing protein  
Size: 531 amino acids; 57359 Da
Subunit: Interacts with CHD4/Mi-2; the interaction is direct
Subcellular location: Nucleus
Sequence caution: Sequence=BAB47476.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAC11317.1; Type=Frameshift; Positions=290; Sequence=CAI95713.1; Type=Erroneous gene model prediction;
1 PDB 3D structure from and Proteopedia for ZGPAT:
4II1 (3D)    
Secondary accessions: E1P5K1 Q4VXN9 Q5JWI9 Q5JWJ0 Q8NC55 Q8WUV4 Q96JI0 Q96JU4 Q9H401
Alternative splicing: 3 isoforms:  Q8N5A5-1   Q8N5A5-2   Q8N5A5-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZGPAT: NX_Q8N5A5

Explore proteomics data for ZGPAT at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N5A5

  • ZGPAT Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZGPAT Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001076582.1  NP_001182582.1  NP_001182583.1  NP_115916.3  NP_852150.2  

    ENSEMBL proteins: 
     ENSP00000348242   ENSP00000349634   ENSP00000403966   ENSP00000358984   ENSP00000332013  
     ENSP00000391176  

    Human Recombinant Protein Products for ZGPAT: 
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    Cloud-Clone Corp. Proteins for ZGPAT 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA19644445

    ZGPAT for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GPATCH: G patch domain containing
    ZC3H: Zinc fingers, CCCH-type domain containing

    2 InterPro protein domains:
     IPR000571 Znf_CCCH
     IPR000467 G_patch_dom

    Graphical View of Domain Structure for InterPro Entry Q8N5A5

    ProtoNet protein and cluster: Q8N5A5

    2 Blocks protein domains:
    IPB000467 D111/G-patch domain
    IPB000571 Zn-finger


    UniProtKB/Swiss-Prot: ZGPAT_HUMAN, Q8N5A5
    Similarity: Contains 1 C3H1-type zinc finger
    Similarity: Contains 1 G-patch domain


    ZGPAT for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZGPAT_HUMAN, Q8N5A5
    Function: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses
    transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates
    expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes
    of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis
    Induction: Down-regulated in breast carcinomas

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IDA19644445
    GO:0005515protein binding IPI19644445
    GO:0008270zinc ion binding ----
    GO:0043565sequence-specific DNA binding IDA19644445
         
    ZGPAT for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZGPAT:
     Synthetic lethal with Ras 

    Animal Models:
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZGPAT


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZGPAT

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/20 Interacting proteins for ZGPAT (Q8N5A52, 3 ENSP000003320134) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HDAC1Q135472, ENSP000003626494MINT-7943970 MINT-7944011 MINT-7943765 STRING: ENSP00000362649
    HDAC2Q927692, ENSP000003813314MINT-7943970 MINT-7944011 MINT-7943765 STRING: ENSP00000381331
    MTA2O947762, ENSP000002788234MINT-7943970 MINT-7944011 MINT-7943765 STRING: ENSP00000278823
    RBBP7Q165762, ENSP000003694274MINT-7944011 MINT-7943765 STRING: ENSP00000369427
    RBBP4Q090282, ENSP000003625924MINT-7944011 MINT-7943765 STRING: ENSP00000362592
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0007175negative regulation of epidermal growth factor-activated receptor activity IDA19644445
    GO:0045892negative regulation of transcription, DNA-dependent IDA19644445

    ZGPAT for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZGPAT

    Search CenterWatch for drugs/clinical trials and news about ZGPAT

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZGPAT gene (6 alternative transcripts): 
    NM_181484.1  NM_001083113.1  NM_001195653.1  NM_001195654.1  NM_032527.4  NM_181485.2  

    Unigene Cluster for ZGPAT:

    Zinc finger, CCCH-type with G patch domain
    Hs.590868  [show with all ESTs]
    Unigene Representative Sequence: NM_032527
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000355969 ENST00000477340 ENST00000490623(uc002ygj.2 uc010gkl.2 uc002ygn.4 uc011abi.2)
    ENST00000357119(uc010gkk.2 uc002ygm.3) ENST00000431125 ENST00000369967
    ENST00000328969(uc002ygk.3) ENST00000486025(uc002ygp.4) ENST00000472711
    ENST00000478385 ENST00000468235 ENST00000484569 ENST00000448100(uc002ygi.2)

    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate ZGPAT:
    hsa-miR-198 hsa-miR-34b
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    Inhib. RNA
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    Additional mRNA sequence: 

    AB058750.3 AK027878.1 AK307368.1 AK314726.1 BC019338.1 BC032612.1 BC127798.1 

    24 DOTS entries:

    DT.92425170  DT.100822150  DT.109754  DT.120824945  DT.100822148  DT.120824969  DT.100822149  DT.120824949 
    DT.92425169  DT.100822143  DT.120825034  DT.100756802  DT.120824906  DT.120824895  DT.120824898  DT.100822145 
    DT.92425168  DT.100676962  DT.100822142  DT.120824974  DT.120825090  DT.95158424  DT.97816282  DT.101982338 

    24/291 AceView cDNA sequences (see all 291):

    CR604734 CR626338 BQ069562 CB156612 AI261465 BM912404 CR616647 NM_017806 
    BM916471 BC052306 NM_020062 CR592410 AK000413 AI671731 CR595933 AA328684 
    CR593736 BQ673062 BF337599 AI240959 BM974581 BC017446 BM846083 BC017016 

    GeneLoc Exon Structure

    5/16 Alternative Splicing Database (ASD) splice patterns (SP) for ZGPAT (see all 16)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c · 6d ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b ·
    SP1:                    -     -                                         -                 -     -     -           -                                             
    SP2:                                                                    -           -     -     -     -           -                                             
    SP3:                                                                    -                 -     -                 -                                             
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                  -     -   

    ExUns: 10c ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c · 14d ^ 15a · 15b · 15c
    SP1:                                                                              
    SP2:                                                                              
    SP3:                                                                              
    SP4:        -                                                                     
    SP5:  -     -                 -                                                   


    ECgene alternative splicing isoforms for ZGPAT

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZGPAT expression in normal human tissues (normalized intensities)      ZGPAT embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCAGCAAGAG
    ZGPAT Expression
    About this image


    ZGPAT expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 5 entries
             lymphocytes   
     
     Lymph (Hematopoietic System)
             lymph node   
     
     Eye (Sensory Organs)
             retinal amacrine cell p0   
     
     Neural Tube (Nervous System)
             Telencephalon
     
     Thymus (Hematopoietic System)

    See ZGPAT Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZGPAT

    SOURCE GeneReport for Unigene cluster: Hs.590868

    UniProtKB/Swiss-Prot: ZGPAT_HUMAN, Q8N5A5
    Tissue specificity: Widely expressed

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZGPAT

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ZGPAT gene from 9/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zgpat1 , 5 zinc finger, CCCH-type with G patch domain1, 5 80.88(n)1
    80.94(a)1
      2 (103.63 cM)5
    2290071  NM_001048148.11  NP_001041613.11 
     1813649285 
    chicken
    (Gallus gallus)
    Aves ZGPAT1 zinc finger, CCCH-type with G patch domain 68.15(n)
    68.53(a)
      419260  XM_003642486.1  XP_003642534.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZGPAT6
    Uncharacterized protein
    63(a)
    1 ↔ 1
    GL343401.1(923707-929198)
    African clawed frog
    (Xenopus laevis)
    Amphibia BU914358.12   -- 75.43(n)    BU914358.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC055224.12   -- 75.42(n)   393457  BC055224.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG47091 CG4709 45.1(n)
    33.67(a)
      34324  NM_135487.3  NP_609331.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C33H5.171 Protein C33H5.17 38.38(n)
    28.38(a)
      177568  NM_068895.2  NP_501296.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G248301 zinc finger CCCH domain-containing protein 22 39.1(n)
    26.92(a)
      817020  NM_128042.4  NP_180056.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g07930001 hypothetical protein 42.09(n)
    31.14(a)
      4330984  NM_001054900.1  NP_001048365.1 


    ENSEMBL Gene Tree for ZGPAT (if available)
    TreeFam Gene Tree for ZGPAT (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/712 SNPs in ZGPAT are shown (see all 712)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0255394
    ----see VAR_0255392 S R mis40--------
    rs558708071,2
    C--62321816(+) GTGAG-/GTGTGTGT 5 -- int11Minor allele frequency- GTG:0.00NA 2
    rs1419499681,2
    --62341823(+) ATTCTA/CTAGAG 5 -- int10--------
    rs1842148501,2
    --62341907(+) CCCACA/GGTCCA 5 -- int10--------
    rs60625011,2
    C,F,A,H--62341931(+) TCATTT/GATTAA 5 -- int124Minor allele frequency- G:0.12NS EA NA 2826
    rs1890222791,2
    --62342161(+) TAACAC/TATTTA 5 -- int10--------
    rs1817289921,2
    --62342199(+) ATGAAC/TAATTA 5 -- int10--------
    rs1847324951,2
    --62342226(+) ATTTCC/GCTAAG 5 -- int10--------
    rs1905359471,2
    --62342303(+) AGGTAA/GTTTTC 5 -- int10--------
    rs1463168181,2
    C--62342336(+) TGACCA/GTGTAA 5 -- int10--------

    HapMap Linkage Disequilibrium report for ZGPAT (62338794 - 62370456 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/33 variations for ZGPAT (see all 33):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv5348CNV Deletion18987735
    esv2722960CNV Deletion23290073
    esv2722959CNV Deletion23290073
    esv2722965CNV Deletion23290073
    esv2722966CNV Deletion23290073
    esv2661713CNV Deletion23128226
    esv2722961CNV Deletion23290073
    esv2722964CNV Deletion23290073
    esv2722963CNV Deletion23290073
    dgv4649n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for ZGPAT:    About MalaCards
    crohn's disease    inflammatory bowel disease


    ZGPAT for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZGPAT
    Human Genome Epidemiology (HuGE) Navigator: ZGPAT (2 documents)

    Export disorders for ZGPAT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZGPAT gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with ZGPAT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. (PubMed id 21102463)1, 4 Franke A....Parkes M. (2010)
    2. Genome-wide searching of rare genetic variants in WTC CC data. (PubMed id 20549515)1, 4 Feng T. and Zhu X. (2010)
    3. Investigation of reported associations between the 20 q13 and 21q22 loci and pediatric-onset Crohn's disease in Canadian children. (PubMed id 19623168)1, 4 Amre D.K....Levy E. (2009)
    4. ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis. (PubMed id 19644445)1, 2 Li R.... Shang Y. (2009)
    5. Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. (PubMed id 18758464)1, 4 Kugathasan S....Hakonarson H. (2008)
    6. Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets. (PubMed id 16952911)1, 3 Ordway J.M....Jeddeloh J.A. (2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    10. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84619 HGNC: 15948 AceView: FLJ20406andSLC2A4RGandKIAA1847 Ensembl:ENSG00000197114 euGenes: HUgn84619
    ECgene: ZGPAT H-InvDB: ZGPAT

    (According to HUGE)
    About This Section
    HUGE: KIAA1847

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZGPAT Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZGPAT gene:
    Search GeneIP for patents involving ZGPAT

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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