Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZG16B Gene

Aliases for ZG16B Gene

  • Zymogen Granule Protein 16B 2 3
  • Jacalin-Like Lectin Domain Containing 2 2 3
  • Pancreatic Adenocarcinoma Upregulated Factor 3
  • Zymogen Granule Protein 16 Homolog B (Rat) 2
  • Zymogen Granule Protein 16 Homolog B 3
  • Endocrine And Exocrine Protein 3
  • HRPE773 3
  • PRO1567 3
  • JCLN2 3
  • EECP 3
  • PAUF 3

External Ids for ZG16B Gene

Summaries for ZG16B Gene

GeneCards Summary for ZG16B Gene

ZG16B (Zymogen Granule Protein 16B) is a Protein Coding gene. Diseases associated with ZG16B include adenocarcinoma and pancreatic ductal adenocarcinoma. An important paralog of this gene is ZG16.

Gene Wiki entry for ZG16B Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZG16B Gene

Genomics for ZG16B Gene

Genomic Location for ZG16B Gene

Start:
2,830,169 bp from pter
End:
2,839,585 bp from pter
Size:
9,417 bases
Orientation:
Plus strand

Genomic View for ZG16B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZG16B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZG16B Gene

Regulatory Elements for ZG16B Gene

Proteins for ZG16B Gene

  • Protein details for ZG16B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96DA0-ZG16B_HUMAN
    Recommended name:
    Zymogen granule protein 16 homolog B
    Protein Accession:
    Q96DA0
    Secondary Accessions:
    • A6NIY1
    • B2R4F6
    • Q6UW28

    Protein attributes for ZG16B Gene

    Size:
    208 amino acids
    Molecular mass:
    22739 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAQ89380.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAG34753.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ZG16B Gene

neXtProt entry for ZG16B Gene

Proteomics data for ZG16B Gene at MOPED

Post-translational modifications for ZG16B Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn197

Other Protein References for ZG16B Gene

No data available for DME Specific Peptides for ZG16B Gene

Domains for ZG16B Gene

Protein Domains for ZG16B Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

ZG16B_HUMAN
Family:
  • Belongs to the jacalin lectin family.:
    • Q96DA0
genes like me logo Genes that share domains with ZG16B: view

No data available for Gene Families for ZG16B Gene

Function for ZG16B Gene

Gene Ontology (GO) - Molecular Function for ZG16B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0030246 carbohydrate binding IEA --
genes like me logo Genes that share ontologies with ZG16B: view

Phenotypes for ZG16B Gene

GenomeRNAi human phenotypes for ZG16B:
genes like me logo Genes that share phenotypes with ZG16B: view

miRNA for ZG16B Gene

miRTarBase miRNAs that target ZG16B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZG16B Gene

Localization for ZG16B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZG16B Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZG16B Gene COMPARTMENTS Subcellular localization image for ZG16B gene
Compartment Confidence
extracellular 3
cytosol 1
lysosome 1
nucleus 1

Gene Ontology (GO) - Cellular Components for ZG16B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 16502470
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with ZG16B: view

Pathways for ZG16B Gene

SuperPathways for ZG16B Gene

No Data Available

Interacting Proteins for ZG16B Gene

Gene Ontology (GO) - Biological Process for ZG16B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001895 retina homeostasis IEP 23580065
genes like me logo Genes that share ontologies with ZG16B: view

No data available for Pathways by source for ZG16B Gene

Transcripts for ZG16B Gene

Unigene Clusters for ZG16B Gene

Zymogen granule protein 16B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZG16B Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c
SP1: - -
SP2: -
SP3:
SP4: -

Relevant External Links for ZG16B Gene

GeneLoc Exon Structure for
ZG16B
ECgene alternative splicing isoforms for
ZG16B

Expression for ZG16B Gene

mRNA expression in normal human tissues for ZG16B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZG16B Gene

This gene is overexpressed in Minor Salivary Gland (52.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZG16B Gene

SOURCE GeneReport for Unigene cluster for ZG16B Gene Hs.105887

genes like me logo Genes that share expressions with ZG16B: view

Orthologs for ZG16B Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZG16B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZG16B 36
  • 99.2 (n)
  • 98.08 (a)
ZG16B 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 41 (a)
OneToMany
-- 37
  • 45 (a)
OneToMany
-- 37
  • 52 (a)
OneToMany
ZG16B 36
  • 68.1 (n)
  • 53.99 (a)
dog
(Canis familiaris)
Mammalia ZG16B 36
  • 64.52 (n)
  • 52.86 (a)
ZG16B 37
  • 48 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Sbp 37
  • 24 (a)
OneToMany
Sbpl 37
  • 20 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 29 (a)
OneToMany
-- 37
  • 29 (a)
OneToMany
Species with no ortholog for ZG16B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZG16B Gene

ENSEMBL:
Gene Tree for ZG16B (if available)
TreeFam:
Gene Tree for ZG16B (if available)

Paralogs for ZG16B Gene

Paralogs for ZG16B Gene

Selected SIMAP similar genes for ZG16B Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZG16B: view

Variants for ZG16B Gene

Sequence variations from dbSNP and Humsavar for ZG16B Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs12373 -- 2,832,196(-) ACCAC(A/C)CAGAT utr-variant-3-prime
rs758189 -- 2,831,674(-) GGGTC(C/T)CTGAC intron-variant
rs886953 -- 2,832,266(-) CAGAA(C/G)CTTTA utr-variant-3-prime
rs929435 -- 2,829,560(-) CCTCA(C/T)CTGGG upstream-variant-2KB
rs1860061 -- 2,830,959(-) ACCGT(C/G)TCCGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZG16B Gene

Variant ID Type Subtype PubMed ID
nsv905152 CNV Loss 21882294
nsv905162 CNV Gain 21882294
nsv905165 CNV Loss 21882294
nsv905169 CNV Loss 21882294
nsv905170 CNV Loss 21882294
dgv2574n71 CNV Loss 21882294
esv2663371 CNV Deletion 23128226

Relevant External Links for ZG16B Gene

HapMap Linkage Disequilibrium report
ZG16B

Disorders for ZG16B Gene

genes like me logo Genes that share disorders with ZG16B: view

No data available for UniProtKB/Swiss-Prot for ZG16B Gene

Publications for ZG16B Gene

  1. Crystal structures of human secretory proteins ZG16p and ZG16b reveal a Jacalin-related beta-prism fold. (PMID: 21110947) Kanagawa M. … Yamaguchi Y. (Biochem. Biophys. Res. Commun. 2011) 2 3 4
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Mass spectrometry allows direct identification of proteins in large genomes. (PMID: 11678034) Kuster B. … Mann M. (Proteomics 2001) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZG16B Gene

Sources for ZG16B Gene

Back to Top

Content