ZFYVE26 Gene
protein-coding GIFtS: 51
GCID: GC14M068194
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|
zinc finger, FYVE domain containing 26(Previous names: spastic paraplegia 15 (complicated, autosomal recessive)...)
(Previous symbol: SPG15)
| |
Aliases
for ZFYVE26 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger, FYVE Domain Containing 261 2 | | Spastic Paraplegia 15 (Complicated, Autosomal Recessive)1 | | SPG151 2 5 | | Spastizin3 | | KIAA03211 3 5 | | Zinc Finger FYVE Domain-Containing Protein 262 | | FYVE-CENT2 3 | | Spastizin3 | | FYVE Domain-Containing Centrosomal Protein2 3 | | |
Export aliases for ZFYVE26 gene to outside databasesPrevious GC identifers: GC14M062006 GC14M066203 GC14M067282 GC14M048382 |
Summaries
for ZFYVE26 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZFYVE26:
This gene encodes a protein which contains a FYVE zinc finger binding domain. The presence of this domain is thought totarget these proteins to membrane lipids through interaction with phospholipids in the membrane. Mutations in thisgene are associated with autosomal recessive spastic paraplegia-15. (provided by RefSeq, Oct 2008)
UniProtKB/Swiss-Prot: ZFY26_HUMAN, Q68DK2Function: Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited tothe midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologousrecombination DNA double-strand break repair
|
Genomic Views
for ZFYVE26 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZFYVE26 gene promoter:
HFH-3 POU3F2 C/EBPalpha FOXI1 PPAR-gamma1 FOXC1 FOXO4 USF-1 PPAR-gamma2 En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZFYVE26
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZFYVE26 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q24.1 Ensembl cytogenetic band: 14q24.1 HGNC cytogenetic band: 14q23.3ZFYVE26 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M068194: view genomic region
(about GC identifiers)
Start:
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68,194,091 bp from pter |
End:
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68,283,307 bp from pter |
Size:
|
89,217 bases |
Orientation:
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minus strand |
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Proteins
for ZFYVE26 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZFY26_HUMAN, Q68DK2 (See
protein sequence)Recommended Name: Zinc finger FYVE domain-containing protein 26 Size: 2539 amino acids; 284576 Da
Subunit: Interacts with AP5Z1, AP5B1, AP5S1 and SPG11. Interacts with TTC19 and KIF13A
Subcellular location: Cytoplasm, cytoskeleton, centrosome. Midbody. Note=Localizes to the centrosome during all stagesof the cell cycle. Recruited to the midbody during cytokinesis by KIF13A
Sequence caution: Sequence=BAG11658.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=CAD97882.1; Type=Erroneous termination; Positions=1463; Note=Translated as Gln;
Secondary accessions: B1B5Y3 B4E2U3 O15035 Q68DT9 Q6AW90 Q6ZR50 Q7Z3A4 Q7Z3I1 Q8N4W7Alternative splicing: 4 isoforms: Q68DK2-1 Q68DK2-2 Q68DK2-4 Q68DK2-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZFYVE26: NX_Q68DK2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q68DK2
ZFYVE26 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_056161.2
ENSEMBL proteins: ENSP00000251119 ENSP00000450431 ENSP00000452142 ENSP00000450603
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ZFYVE26 for ontologies About GeneDecksing
ZFYVE26 Antibody Products:
Assay Products for ZFYVE26: |
Protein
Domains /
Families
for ZFYVE26 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZFYVE26 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q68DK2ProtoNet protein and cluster: Q68DK2 1 Blocks protein family: IPB000306 Zn-finger
UniProtKB/Swiss-Prot: ZFY26_HUMAN, Q68DK2Domain: The FYVE-type zinc finger mediates binding to phosphatidylinositol 3-phosphate and recruitment to the midbodyduring cytokinesisSimilarity: Contains 1 FYVE-type zinc finger |
Function
for ZFYVE26 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZFY26_HUMAN, Q68DK2Function: Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited tothe midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologousrecombination DNA double-strand break repair
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE26 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE26
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZFYVE26 (NM_015346) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZFYVE26 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFYVE26 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFYVE26 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- | | GO:0032266 | phosphatidylinositol-3-phosphate binding |
IDA | -- | | GO:0046872 | metal ion binding |
IEA | -- |
ZFYVE26 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZFYVE26 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cytoskeletal Signaling | | | 2 | PI3K / Akt Signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Cell Signaling Technology (CST) Pathways for ZFYVE26
ZFYVE26 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZFYVE26
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
5 Interacting proteins for ZFYVE26 (Q68DK23 ENSP000002511194) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
ZFYVE26 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZFYVE26 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZFYVE26
Search CenterWatch for drugs/clinical trials and news about ZFYVE26 / ZFY26
|
Transcripts
for ZFYVE26 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZFYVE26 gene: NM_015346.3 Unigene Cluster for ZFYVE26: Zinc finger, FYVE domain containing 26 Hs.98041 [show with all ESTs]Unigene Representative Sequence: NM_01534611 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000394455 ENST00000347230(uc001xka.2 uc010tsz.1) ENST00000554557
ENST00000554523 ENST00000557306(uc001xkb.3) ENST00000554783 ENST00000555452(uc001xkc.4)
ENST00000557204 ENST00000557366(uc010tta.2) ENST00000557407 ENST00000553399
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE26 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE26
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZFYVE26 (NM_015346) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZFYVE26 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFYVE26 |
Additional cDNA sequence: AB002319.1 AB425197.1 AK024743.1 AK055455.1 AK304428.1 AK308233.1 BC008927.2 BC013909.2 BC033235.1 BC144594.1 BX538025.1 BX648036.1 BX648683.1 CR749276.1 CR749365.1 13 DOTS entries: DT.315080 DT.100812129 DT.75103071 DT.75122974 DT.100775498 DT.101983955 DT.100650404 DT.40250645 DT.75195549 DT.101983954 DT.95359593 DT.91759756 DT.95089137 24/149 AceView cDNA sequences (see all 149): AA614825 CB269757 BM771053 BU175284 BQ066246 BX441741 BU859628 BX538025 BU930934 BQ011604 BM988307 BQ184112 BX648683 BQ058240 BC033235 BX112682 AB002319 BQ012672 BQ010951 NM_015346 CF552568 BG059368 BC008927 AL044061
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ZFYVE26 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32a | · | 32b | ^ | 33 | ^ | 34a | · | 34b | ^ | 35a | · | 35b | ^ | 36a | · | 36b | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40 | ^ | 41a | · | 41b | ^ | 42 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZFYVE26
|
Expression
for ZFYVE26 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZFYVE26 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZFYVE26 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZFYVE26
SOURCE GeneReport for Unigene cluster: Hs.98041
UniProtKB/Swiss-Prot: ZFY26_HUMAN, Q68DK2Tissue specificity: Strongest expression in the adrenal gland, bone marrow, adult brain, fetal brain, lung, placenta,prostate, skeletal muscle, testis, thymus, and retina. Intermediate levels are detected in other structures, includingthe spinal cord
SABiosciences Custom PCR Arrays for ZFYVE26
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZFYVE26
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZFYVE26 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZFYVE26 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZFYVE26 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFYVE26 |
Orthologs
for ZFYVE26 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ZFYVE26 gene from 7/18 species (see all 18) About this table
ENSEMBL Gene Tree for ZFYVE26 (if available)
TreeFam Gene Tree for ZFYVE26 (if available) |
Paralogs
for ZFYVE26 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZFYVE26 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZFYVE26 (68194091 - 68283307 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZFYVE26
1 CNV: 35261
Human Gene Mutation Database (HGMD): ZFYVE26
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZFYVE26 |
|
Disorders
/ Diseases
for ZFYVE26 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZFYVE26 for disorders About GeneDecksing
OMIM gene information: 612012
OMIM disorders: 270700
UniProtKB/Swiss-Prot: ZFY26_HUMAN, Q68DK2
Defects in ZFYVE26 are the cause of spastic paraplegia autosomal recessive type 15 (SPG15) [MIM:270700]; alsoknown as spastic paraplegia and retinal degeneration or Kjellin syndrome. Spastic paraplegia is a neurodegenerativedisorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progressionand the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness andstiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladdersymptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. SPG15is a complex form associated with additional neurological symptoms such as cognitive deterioration or mentalretardation, axonal neuropathy, mild cerebellar signs, and, less frequently, a central hearing deficit, decreasedvisual acuity, or retinal degeneration
12  diseases for ZFYVE26: About MalaCardsspastic paraplegia 15 spastic paraplegia paraplegia spasticity
hereditary spastic paraplegia corpus callosum axonal neuropathy optic atrophy
retinal degeneration neuropathy retinitis prostatitis
1 disease from the University of Copenhagen DISEASES database for ZFYVE26:Paraplegia Human Genome Epidemiology (HuGE) Navigator: ZFYVE26 (1 document)
Export disorders for ZFYVE26 gene to outside databases
|
Publications
for ZFYVE26 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZFYVE26 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with ZFYVE26) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of the SPG15 gene, encoding spastizin, as a frequent cause of complicated autosomal-recessive spastic paraplegia, including Kjellin syndrome. (PubMed id 18394578)1, 2, 3 Hanein S.... Stevanin G. (2008)
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (1997)
- PtdIns(3)P controls cytokinesis through KIF13A-mediat ed recruitment of FYVE-CENT to the midbody. (PubMed id 20208530)1, 2 Sagona A.P....Stenmark H. (2010)
- SPG15 is the second most common cause of hereditary s pastic paraplegia with thin corpus callosum. (PubMed id 19805727)1, 2 Goizet C....Stevanin G. (2009)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Cellular distribution and subcellular localization of spatacsin and spastizin, two proteins involved in hereditary spastic paraplegi a. (PubMed id 21545838)1 Murmu R.P....Stevanin G. (2011)
- A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis. (PubMed id 21455500)1 Sagona A.P....Stenmark H. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- A genome-scale DNA repair RNAi screen identifies SPG4 8 as a novel gene associated with hereditary spastic paraplegia. (PubMed id 20613862)2 SA8abicki M....Buchholz F. (2010)
- Spastic paraplegia with thinning of the corpus callosum and white matter abnormalities: further mutations and relative frequency in ZFYVE26/SPG15 in the Italian population. (PubMed id 19084844)2 Denora P.S....Santorelli F.M. (2009)
|
External Searches for ZFYVE26 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZFYVE26 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZFYVE26 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZFYVE26 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZFYVE26 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZFYVE26 gene:
Search GeneIP for patents involving ZFYVE26
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZFYVE26 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | OriGene Antibodies for ZFYVE26 | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZFYVE26 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZFYVE26 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for ZFYVE26 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE26 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE26 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZFYVE26 | | OriGene Custom Protein Services for ZFYVE26 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZFYVE26 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZFYVE26 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZFYVE26 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZFYVE26 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZFYVE26 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZFYVE26 |
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| | | | Search Tocris compounds for ZFYVE26 |
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 | | | ZFYVE26 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFYVE26 |
|  |  |  | | | | ThermoFisher Antibodies for ZFYVE26 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFYVE26 |
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