Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ZFYVE19 Gene

protein-coding   GIFtS: 49
GCID: GC15P041099

Zinc Finger, FYVE Domain Containing 19

  Search for ZFYVE19
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Zinc Finger, FYVE Domain Containing 191 2
MPFYVE2 3
MLL Partner Containing FYVE Domain2 3
Zinc Finger FYVE Domain-Containing Protein 192

External Ids:    HGNC: 207581   Entrez Gene: 849362   Ensembl: ENSG000001661407   UniProtKB: Q96K213   
ORGUL members:         

Export aliases for ZFYVE19 gene to outside databases

Previous GC identifers: GC15P033995 GC15P038678 GC15P038815 GC15P038886 GC15P017947


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for ZFYVE19 Gene:
ZFYVE19 (zinc finger, FYVE domain containing 19) is a protein-coding gene.

Gene Wiki entry for ZFYVE19 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000015.10  NC_018926.2  NT_010194.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZFYVE19 gene promoter:
         Bach1   AhR   Max1   Nkx2-5   PPAR-gamma1   IRF-7A   PPAR-gamma2   ATF6   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ZFYVE19

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZFYVE19


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.1   Ensembl cytogenetic band:  15q15.1   HGNC cytogenetic band: 15q14

ZFYVE19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZFYVE19 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P041099:  view genomic region     (about GC identifiers)

Start:
41,099,274 bp from pter      End:
41,106,767 bp from pter
Size:
7,494 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ZFY19_HUMAN, Q96K21 (See protein sequence)
Recommended Name: Zinc finger FYVE domain-containing protein 19  
Size: 471 amino acids; 51546 Da
Sequence caution: Sequence=AAH21092.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAO73862.1; Type=Frameshift; Positions=459; Sequence=BAB55338.1; Type=Erroneous initiation;
Note=Translation N-terminally extended;
Secondary accessions: B3KVB2 C9JNF4 H3BUF9 Q86WC2 Q8WU96
Alternative splicing: 4 isoforms:  Q96K21-1   Q96K21-2   Q96K21-3   Q96K21-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZFYVE19: NX_Q96K21

Explore proteomics data for ZFYVE19 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZFYVE19 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001070736.1  NP_001245349.1  NP_001245350.1  NP_116239.3  

    ENSEMBL proteins: 
     ENSP00000456223   ENSP00000457617   ENSP00000347498   ENSP00000337824   ENSP00000299173  
     ENSP00000455157   ENSP00000456304   ENSP00000458096   ENSP00000454704   ENSP00000456679  
     ENSP00000456485   ENSP00000457839  

    ZFYVE19 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ZFYVE19
    OriGene Protein Over-expression Lysate for ZFYVE19
    OriGene MassSpec for ZFYVE19
    OriGene Custom Protein Services for ZFYVE19
    GenScript Custom Purified and Recombinant Proteins Services for ZFYVE19
    Novus Biologicals ZFYVE19 Protein
    Novus Biologicals ZFYVE19 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZFYVE19

     
    Search eBioscience for Proteins for ZFYVE19 

    ZFYVE19 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for ZFYVE19
    OriGene Custom Antibody Services for ZFYVE19
    Novus Biologicals ZFYVE19 Antibodies
    Abcam antibodies for ZFYVE19
    Cloud-Clone Corp. Antibodies for ZFYVE19
    ThermoFisher Antibodies for ZFYVE19
    LSBio Antibodies in human, mouse, rat for ZFYVE19

    ZFYVE19 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZFYVE19
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZFYVE19
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZFYVE19
    Cloud-Clone Corp. CLIAs for ZFYVE19
    Search eBioscience for ELISAs for ZFYVE19 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZFYVE: Zinc fingers, FYVE domain containing

    5 InterPro protein domains:
     IPR001841 Znf_RING
     IPR000306 Znf_FYVE
     IPR013083 Znf_RING/FYVE/PHD
     IPR017455 Znf_FYVE-rel
     IPR011011 Znf_FYVE_PHD

    Graphical View of Domain Structure for InterPro Entry Q96K21

    ProtoNet protein and cluster: Q96K21

    2 Blocks protein domains:
    IPB000306 Zn-finger
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: ZFY19_HUMAN, Q96K21
    Similarity: Contains 1 FYVE-type zinc finger


    Find genes that share domains with ZFYVE19           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17500595
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    Find genes that share ontologies with ZFYVE19           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ZFYVE19:
     Increased cell death HMECs cel 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZFYVE19
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZFYVE19

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZFYVE19
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZFYVE19

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZFYVE19:
    hsa-mir-3117-3p (MIRT052657)

    Block miRNA regulation of human, mouse, rat ZFYVE19 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ZFYVE19:
    hsa-miR-622
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZFYVE19
    Predesigned siRNA for gene silencing in human, mouse, rat ZFYVE19

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZFYVE19

    Clone
    Products:
         
    OriGene clones in human, mouse for ZFYVE19 (see all 8)
    OriGene ORF clones in mouse, rat for ZFYVE19
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZFYVE19 (NM_001077268)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZFYVE19
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFYVE19

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZFYVE19
    Browse ESI BIO Cell Lines and PureStem Progenitors for ZFYVE19 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFYVE19


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZFYVE19
    Interactions:

        Search GeneGlobe Interaction Network for ZFYVE19

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ZFYVE19 (Q96K213 ENSP000003474984) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SH3BP5LQ7L8J43, ENSP000003554284I2D: score=5 STRING: ENSP00000355428
    SH3BP5ENSP000003733014STRING: ENSP00000373301
    COPAENSP000003570484STRING: ENSP00000357048
    COPEENSP000002628124STRING: ENSP00000262812
    PIKFYVEENSP000002643804STRING: ENSP00000264380
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZFYVE19 (ZFY19)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ZFYVE19 gene (4 alternative transcripts): 
    NM_001077268.1  NM_001258420.1  NM_001258421.1  NM_032850.4  

    Unigene Cluster for ZFYVE19:

    Zinc finger, FYVE domain containing 19
    Hs.121676  [show with all ESTs]
    Unigene Representative Sequence: NM_001077268
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000570108 ENST00000564258 ENST00000355341(uc001zmt.1 uc001zmu.1 uc001zmv.1)
    ENST00000336455 ENST00000299173 ENST00000568062 ENST00000563530 ENST00000566407
    ENST00000567756 ENST00000561617 ENST00000569057 ENST00000561768 ENST00000560078
    ENST00000566767 ENST00000570162 ENST00000563497
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZFYVE19 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ZFYVE19:
    hsa-miR-622
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZFYVE19
    Predesigned siRNA for gene silencing in human, mouse, rat ZFYVE19
    Clone
    Products:
         
    OriGene clones in human, mouse for ZFYVE19 (see all 8)
    OriGene ORF clones in mouse, rat for ZFYVE19
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZFYVE19 (NM_001077268)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZFYVE19
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFYVE19
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ZFYVE19
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZFYVE19
      QuantiTect SYBR Green Assays in human, mouse, rat ZFYVE19
      QuantiFast Probe-based Assays in human, mouse, rat ZFYVE19

    Additional mRNA sequence: 

    AF445414.1 AK027746.1 AK122779.1 AK225553.1 BC015738.1 BC021092.1 

    14 DOTS entries:

    DT.100703726  DT.95270602  DT.424941  DT.121061248  DT.121061200  DT.447001  DT.97855321  DT.121061265 
    DT.121061270  DT.100792339  DT.100642595  DT.95242113  DT.95242222  DT.95257371 

    Selected AceView cDNA sequences (see all 184):

    BM704933 AF445414 CR625018 CR614847 BM925120 AA761558 CA309126 BQ438184 
    BM998461 BU628326 BM824270 BQ428312 AA773608 AK122779 CA489708 BQ937181 
    BQ009568 CB241353 AW015263 BE302320 BM676967 BI860679 CN481117 BU734353 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZFYVE19 (see all 13)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b · 11c ^ 12 ^
    SP1:        -     -     -     -     -     -     -           -     -                                                                                             
    SP2:                                            -     -     -     -                                                                                             
    SP3:                                            -     -     -     -                                                                       -     -     -         
    SP4:                                            -     -     -     -     -     -     -                                                                           
    SP5:                                      -     -     -     -     -                                                                                             

    ExUns: 13a · 13b ^ 14 ^ 15a · 15b · 15c
    SP1:  -                                 
    SP2:  -                                 
    SP3:  -                                 
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for ZFYVE19

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ZFYVE19 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGGGGAGAG
    ZFYVE19 Expression
    About this image

    ZFYVE19 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZFYVE19 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.121676

    UniProtKB/Swiss-Prot: ZFY19_HUMAN, Q96K21
    Tissue specificity: Detected in brain, heart, skeletal muscle, kidney and liver

        Custom PCR Arrays for ZFYVE19
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ZFYVE19
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZFYVE19
    QuantiTect SYBR Green Assays in human, mouse, rat ZFYVE19
    QuantiFast Probe-based Assays in human, mouse, rat ZFYVE19
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFYVE19

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for ZFYVE19 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfyve191 , 5 zinc finger, FYVE domain containing 191, 5 82.52(n)1
    81.65(a)1
      2 (59.97 cM)5
    720081  NM_028054.31  NP_082330.21 
     1192086175 
    chicken
    (Gallus gallus)
    Aves ZFYVE191 zinc finger, FYVE domain containing 19 63.67(n)
    63.75(a)
      423204  NM_001199652.1  NP_001186581.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZFYVE196
    zinc finger, FYVE domain containing 19
    58(a)
    1 ↔ 1
    GL343264.1(446821-461624)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX728472.12   -- 74.72(n)    BX728472.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.61842 Transcribed sequences 79.4(n)    BQ074816.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG156021 CG15602 45.49(n)
    37.46(a)
      32533  NM_132849.3  NP_573077.2 


    ENSEMBL Gene Tree for ZFYVE19 (if available)
    TreeFam Gene Tree for ZFYVE19 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ZFYVE19 (see all 192)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1821787851,2
    --41101715(+) ATAGGA/GAAAGA 4 -- int10--------
    rs1861405321,2
    --41101721(+) AAAGAA/CCCTGC 4 -- int10--------
    rs1464009221,2
    --41101795(+) GCCCTC/TTTGGG 4 -- int10--------
    rs751752931,2
    C,F--41101816(+) AGCTCT/GTCAGC 4 -- int11Minor allele frequency- G:0.03EA 120
    rs1396747151,2
    --41101834(+) CCAGGA/TCAGGC 4 -- int10--------
    rs1429329711,2
    --41101870(+) TGGACC/TGTCTG 4 -- int10--------
    rs798351061,2
    F--41101877(+) TCTGGC/TTGGTC 4 -- int11Minor allele frequency- T:0.01WA 118
    rs1165566741,2
    C,F--41101907(+) GTGACA/GTGAGT 4 -- int11Minor allele frequency- G:0.03WA 118
    rs1395187381,2
    C,F--41102015(+) CTCTGC/ACTTCT 4 -- int11Minor allele frequency- A:0.01EU 1323
    rs2010058581,2
    --41102029(+) AGAGCC/TTCTAT 4 -- int10--------

    HapMap Linkage Disequilibrium report for ZFYVE19 (41099274 - 41106767 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ZFYVE19:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv272589CNV Insertion20981092
    esv267815CNV Insertion20981092
    nsv904102CNV Loss21882294
    nsv904101CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZFYVE19
    DNA2.0 Custom Variant and Variant Library Synthesis for ZFYVE19

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    UniProtKB/Swiss-Prot: ZFY19_HUMAN, Q96K21
  • Note=A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML).
    Translocation t(11;15)(q23;q14) with KMT2A/MLL1


  • Find genes that share disorders with ZFYVE19           About GenesLikeMe


    Export disorders for ZFYVE19 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ZFYVE19 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with ZFYVE19)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. A t(11;15) fuses MLL to two different genes, AF15q14 and a novel gene MPFYVE on chromosome 15. (PubMed id 12618766)1, 2 Chinwalla V....Rowley J.D. (Oncogene 2003)
    4. Development and application of a DNA microarray-based yeast two-hybrid system. (PubMed id 23275563)1 Suter B....Wanker E.E. (Nucleic Acids Res. 2013)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment. (PubMed id 19367720)2 Carrascal M.... Abian J. (J. Proteome Res. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 84936 HGNC: 20758 AceView: ZFYVE19 Ensembl:ENSG00000166140 euGenes: HUgn84936
    ECgene: ZFYVE19 H-InvDB: ZFYVE19

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ZFYVE19 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ZFYVE19 gene:
    Search GeneIP for patents involving ZFYVE19

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for ZFYVE19   OriGene RNAi products in human, mouse, rat for ZFYVE19  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for ZFYVE19  
     OriGene MassSpec something-or-other for ZFYVE19   OriGene clones in human, mouse for ZFYVE19  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZFYVE19   OriGene Purified Protein for ZFYVE19  
     OriGene ORF clones in mouse, rat for ZFYVE19   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZFYVE19   OriGene Custom Protein Services for ZFYVE19  

     
     
     Block miRNA regulation of human, mouse, rat ZFYVE19 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ZFYVE19
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZFYVE19 Predesigned siRNA for gene silencing in human, mouse, rat ZFYVE19
     QuantiFast Probe-based Assays in human, mouse, rat ZFYVE19 QuantiTect SYBR Green Assays in human, mouse, rat ZFYVE19
     Custom PCR Arrays for ZFYVE19 Search Chromatin IP Primers for ZFYVE19
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZFYVE19  Search GeneGlobe Interaction Network for ZFYVE19
     Regulatory tfbs in ZFYVE19 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ZFYVE19 GenScript cDNA clones with any tag delivered in your preferred vector for ZFYVE19
     GenScript Custom Assay Services for ZFYVE19 GenScript Custom overexpressing Cell Line Services for ZFYVE19
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ZFYVE19 (ZFY19)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ZFYVE19 antibodies
     ZFYVE19 proteins
     ZFYVE19 lysates
     Antibodies for ZFYVE19
     See all of Abcam's Antibodies, Kits and Proteins for ZFYVE19
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for ZFYVE19
     Antibodies for ZFYVE19
     ELISAs for ZFYVE19
     CLIAs for ZFYVE19



     Browse ESI BIO Cell Lines and PureStem Progenitors for ZFYVE19
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFYVE19
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ZFYVE19
     Browse SwitchGear Promoter luciferase reporter plasmids for ZFYVE19
     ThermoFisher Antibodies for ZFYVE19
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFYVE19
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZFYVE19
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZFYVE19
     LSBio Antibodies in human, mouse, rat for ZFYVE19
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ZFYVE19
      Search eBioscience for proteins for ZFYVE19
      Search eBioscience for elisas for ZFYVE19
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZFYVE19 gene at Home site.
    Version: 3.12.202 14 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4