ZFYVE16 Gene
protein-coding GIFtS: 54
GCID: GC05P079739
|
|
zinc finger, FYVE domain containing 16
| |
Aliases for ZFYVE16 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Zinc Finger, FYVE Domain Containing 161 2 | | Endosome-Associated FYVE-Domain Protein2 | | PPP1R691 2 | | Protein Phosphatase 1, Regulatory Subunit 692 | | KIAA03051 3 | | Zinc Finger FYVE Domain-Containing Protein 162 | | Endosome-Associated FYVE Domain Protein2 3 | | Endofin3 | | ENDOFIN2 | | |
Export aliases for ZFYVE16 gene to outside databasesPrevious GC identifers: GC05P079942 GC05P079742 GC05P079787 GC05P074911 |
Summaries for ZFYVE16 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ZFYVE16: The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. It ischaracterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain positioned in the middle ofthe molecule (Seet et al., 2004 (PubMed 14613930)).(supplied by OMIM, Mar 2008) UniProtKB/Swiss-Prot: ZFY16_HUMAN, Q7Z3T8Function: May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosomeaggregation. Required to target TOM1 to endosomes Gene Wiki entry for ZFYVE16
|
Genomic Views for ZFYVE16 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006713.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ZFYVE16 gene promoter: C/EBPbeta POU2F1 AML1a AP-1 POU2F1a ATF-2 Msx-1 c-Jun Other transcription factors
Search SABiosciences Chromatin IP Primers for ZFYVE16
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZFYVE16 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q14 Ensembl cytogenetic band: 5q14.1 HGNC cytogenetic band: 5q14.1ZFYVE16 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P079739: view genomic region
(about GC identifiers)
Start:
|
79,703,832 bp from pter |
End:
|
79,775,498 bp from pter |
Size:
|
71,667 bases |
Orientation:
|
plus strand |
|
Proteins for ZFYVE16 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ZFY16_HUMAN, Q7Z3T8 (See
protein sequence)Recommended Name: Zinc finger FYVE domain-containing protein 16 Size: 1539 amino acids; 168903 Da
Subunit: Interacts with the C-terminus of TOM1. Does not interact with TOM1L1 or TOM1L2
Subcellular location: Cytoplasm. Early endosome membrane; Peripheral membrane protein. Note=Localized to earlyendosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P)
Sequence caution: Sequence=BAA20764.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for ZFYVE16:3T7L (3D)
 
Secondary accessions: O15023 Q5H9U2 Q7LAU7 Q86T69 Q8N5L3 Q8NEK3Alternative splicing: 2 isoforms: Q7Z3T8-1 Q7Z3T8-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZFYVE16: NX_Q7Z3T8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z3T8 ZFYVE16 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001098721.1 NP_055548.3 ENSEMBL proteins: ENSP00000337159 ENSP00000423663 ENSP00000426848 ENSP00000422356 ENSP00000426536 ENSP00000421785 ENSP00000426500 Reactome Protein details: Q7Z3T8 Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ZFYVE16 for ontologies About GeneDecksing
ZFYVE16 Antibody Products: Assay Products for ZFYVE16: |
Protein
Domains / Families for ZFYVE16 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZFYVE16 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q7Z3T8ProtoNet protein and cluster: Q7Z3T8 1 Blocks protein family: IPB000306 Zn-finger
UniProtKB/Swiss-Prot: ZFY16_HUMAN, Q7Z3T8Domain: The FYVE-type zinc finger is necessary and sufficient for its localization into early endosomes and mediatesthe association with PI3PSimilarity: Contains 1 FYVE-type zinc finger |
Function for ZFYVE16 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ZFY16_HUMAN, Q7Z3T8Function: May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosomeaggregation. Required to target TOM1 to endosomes
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE16 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE16 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZFYVE16 (NM_001105251) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZFYVE16 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFYVE16  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFYVE16 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
ZFYVE16 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZFYVE16:
|
Pathways & Interactions for ZFYVE16 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by BMP | | | 2 | TGF-beta receptor signaling | | | 3 | TGF-beta signaling pathway | | | 4 | Endocytosis | | | 5 | Signaling by GPCR | |
Pathway sources See GeneCards unified pathways Show all pathways
2 BioSystems Pathways for ZFYVE16 
2
Reactome Pathways for ZFYVE16
2
Kegg Pathways (Kegg details for ZFYVE16):
ZFYVE16 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ZFYVE16
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
 5/27 Interacting proteins for ZFYVE16 (Q7Z3T81, 2, 3 ENSP000003371594) via UniProtKB, MINT, STRING, and/or I2D (see all 27)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
ZFYVE16 for ontologies About GeneDecksing
|
Drugs & Compounds for ZFYVE16 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ZFYVE16 for compounds About GeneDecksing
Browse Tocris compounds for ZFYVE16 1 Novoseek chemical compound relationship for ZFYVE16 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| phosphatidylinositol |
49.5 |
3 |
19887107 (1) |
Search CenterWatch for drugs/clinical trials and news about ZFYVE16 / ZFY16 
|
Transcripts for ZFYVE16 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ZFYVE16 gene (2 alternative transcripts): NM_001105251.1 NM_014733.3 Unigene Cluster for ZFYVE16: Zinc finger, FYVE domain containing 16 Hs.482660 [show with all ESTs]Unigene Representative Sequence: NM_00110525113 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000338008(uc003kgr.4 uc003kgq.4 uc003kgs.4 uc003kgt.4) ENST00000510158 ENST00000505560 ENST00000512558(uc003kgp.3) ENST00000509562 ENST00000510995(uc010jak.2) ENST00000512442 ENST00000511050 ENST00000511829 ENST00000509558 ENST00000507548 ENST00000512907(uc003kgu.4) ENST00000513789
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE16 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE16 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZFYVE16 (NM_001105251) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZFYVE16 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFYVE16  |
Additional cDNA sequence: AB002303.1 AF434817.1 AK090896.1 AK127003.1 AL833087.2 BC030808.1 BX537424.1 CR933621.1 12 DOTS entries: DT.75161116 DT.101983544 DT.75135092 DT.416510 DT.101983543 DT.75100255 DT.92429515 DT.100025221 DT.120873316 DT.425603 DT.95259779 DT.120873281 24/160 AceView cDNA sequences (see all 160): AA443383 AL705583 BM925782 AI362488 AV717110 N21588 CA393193 AI243668 BM976393 AI282629 CB216048 AA349902 AA349612 AA349613 BU735599 AA235268 AA815426 BX106860 BQ884268 CA388945 AI493297 N23475 AA864794 C01346 GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ZFYVE16 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | |
| SP1: | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22a | · | 22b | · | 22c | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ZFYVE16
|
Expression for ZFYVE16 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZFYVE16 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
About this image See ZFYVE16 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ZFYVE16
SOURCE GeneReport for Unigene cluster: Hs.482660 UniProtKB/Swiss-Prot: ZFY16_HUMAN, Q7Z3T8Tissue specificity: Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level inheart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes SABiosciences Custom PCR Arrays for ZFYVE16
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZFYVE16 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZFYVE16 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZFYVE16 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZFYVE16 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFYVE16 |
Orthologs for ZFYVE16 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZFYVE16 gene from 6/19 species (see all 19) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Zfyve161 , 5 |
zinc finger, FYVE domain containing 161, 5 |
81.46(n)1 74.19(a)1 |
  |
13 (47.72 cM)5 2184411 NM_173392.41 NP_775568.11 924871085 |
chicken (Gallus gallus) |
Aves |
ZFYVE161 |
zinc finger, FYVE domain containing 16 |
60.96(n) 49.97(a) |
  |
427315 XM_424894.3 XP_424894.3 |
lizard (Anolis carolinensis) |
Reptilia |
ZFYVE166 |
-- |
48(a) |
1 ↔ 1 |
2(17098407-17121159) |
zebrafish (Danio rerio) |
Actinopterygii |
LOC7946891 |
zinc finger FYVE domain-containing protein 16-like |
51.01(n) 43.99(a) |
  |
794689 XM_001920883.2 XP_001920918.2 |
fruit fly (Drosophila melanogaster) |
Insecta |
Sara6 |
Smad anchor for receptor activation |
25(a) |
1 → many |
2R(17369424-17374618) |
worm (Caenorhabditis elegans) |
Secernentea |
aka-16 |
A Kinase Anchor protein family member (aka-1) |
18(a) |
1 → many |
II(7472685-7478914) |
ENSEMBL Gene Tree for ZFYVE16 (if available) TreeFam Gene Tree for ZFYVE16 (if available)  |
Paralogs for ZFYVE16 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ZFYVE16 gene
- ZFYVE92
1 SIMAP similar gene for ZFYVE16 using alignment to 5 protein entries: ZFY16_HUMAN (see all proteins):ZFYVE9
ZFYVE16 for paralogs About GeneDecksing
|
Genomic Variants for ZFYVE16 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 5 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ZFYVE16 (79703832 - 79775498 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ZFYVE16: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZFYVE16 |
|
Disorders
/ Diseases for ZFYVE16 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZFYVE16 for disorders About MalaCards
ZFYVE16 for disorders About GeneDecksing
OMIM gene information: 608880
OMIM disorders: --
Export disorders for ZFYVE16 gene to outside databases
|
Publications for ZFYVE16 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZFYVE16 gene, integrated from 9 sources (see all 35): (articles sorted by number of sources associating them with ZFYVE16) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Endofin, an endosomal FYVE domain protein. (PubMed id 11546807)1, 2, 3, 9 Seet L.-F. and Hong W. (2001)
- Endofin recruits TOM1 to endosomes. (PubMed id 14613930)1, 2, 9 Seet L.-F.... Hong W. (2004)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
- Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2 Nagase T.... Ohara O. (1997)
- EGF-induced tyrosine phosphorylation of Endofin is de pendent on PI3K activity and proper localization to endosomes. (PubMed id 19887107)1, 9 Toy W....Lim Y.P. (2010)
- Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling. (PubMed id 17272273)1, 9 Chen Y.G....Lu Z. (2007)
- Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells. (PubMed id 17570516)1, 9 Chen Y....Lim Y.P. (2007)
- Endofin acts as a Smad anchor for receptor activation in BMP signaling. (PubMed id 17356069)1, 9 Shi W....Cao X. (2007)
|
External Searches for ZFYVE16 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ZFYVE16 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZFYVE16 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZFYVE16 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ZFYVE16 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZFYVE16 gene: Search GeneIP for patents involving ZFYVE16
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ZFYVE16 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for ZFYVE16 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZFYVE16 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZFYVE16 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ZFYVE16 | | OriGene 3'-UTR Clone for ZFYVE16 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE16 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZFYVE16 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ZFYVE16 | | OriGene Custom Protein Services for ZFYVE16 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZFYVE16 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZFYVE16 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZFYVE16 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZFYVE16 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZFYVE16 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZFYVE16 |
| |
 |  |  |  | |
| | | Search Tocris compounds for ZFYVE16 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | ZFYVE16 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFYVE16 |
|  |  |  | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFYVE16 |
|
|
|
|