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Aliases for ZFP82 Gene

Aliases for ZFP82 Gene

  • ZFP82 Zinc Finger Protein 2 3 5
  • Zinc Finger Protein 545 2 3 4
  • ZNF545 3 4
  • Zinc Finger Protein 82 Homolog (Mouse) 2
  • Zinc Finger Protein 82 Homolog 3
  • Zinc Finger Protein 82 2
  • Zinc Finger Protein 85 3
  • KIAA1948 4
  • Zfp-82 4

External Ids for ZFP82 Gene

Previous HGNC Symbols for ZFP82 Gene

  • ZNF545

Previous GeneCards Identifiers for ZFP82 Gene

  • GC19M041577
  • GC19M036874
  • GC19M036882
  • GC19M033351
  • GC19M036417
  • GC19M036698
  • GC19M036880
  • GC19M036901

Summaries for ZFP82 Gene

GeneCards Summary for ZFP82 Gene

ZFP82 (ZFP82 Zinc Finger Protein) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZFP30.

UniProtKB/Swiss-Prot for ZFP82 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFP82 Gene

Genomics for ZFP82 Gene

Regulatory Elements for ZFP82 Gene

Enhancers for ZFP82 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F036915 1.4 FANTOM5 ENCODE 43.2 -498.0 -497977 1.9 PKNOX1 ARID4B SIN3A ZNF2 YY1 ZNF302 ZNF416 ZNF143 ZNF548 ZNF263 ZNF383 ZNF345 ZNF850 ZNF790-AS1 ZNF793 ZNF585A ZNF568 ZNF607 ZNF529 ZNF567
GH19F036572 1.2 ENCODE 44 -154.9 -154851 3.0 HDGF PKNOX1 CREB3L1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF383 ZFP82 ZNF345 ZNF793 LINC00665 ZNF529 ZNF790-AS1 ZNF461 ZNF568 LINC01534
GH19F035429 1.6 FANTOM5 Ensembl ENCODE 32.2 +987.8 987821 2.4 PKNOX1 ZNF493 ZFP64 ZNF155 ZEB1 ZNF354C ZNF138 KLF7 ZNF548 ZNF202 TMEM147-AS1 HAUS5 KMT2B ZNF792 RBM42 ZNF146 ZFP82 ENSG00000267049 SDHAF1 LINC00665
GH19F036052 1.2 ENCODE 41.1 +363.9 363854 3.9 MLX DMAP1 YY1 SLC30A9 ZNF143 ZNF548 SP3 NFYC MEF2D ZNF610 ZNF345 ZNF850 RBM42 ZNF568 ZFP82 KMT2B ZNF146 ZNF461 ZNF790-AS1 ZNF529
GH19F035882 1.3 Ensembl ENCODE 32.2 +536.3 536258 0.4 ZFP64 ZNF493 ARID4B FEZF1 ZNF121 ZNF302 KLF7 ZNF202 SP3 MIER2 ZNF345 TMEM147-AS1 ZNF850 ZNF567 HAUS5 KMT2B ZNF790-AS1 ZNF146 ZNF792 ZNF790
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZFP82 on UCSC Golden Path with GeneCards custom track

Promoters for ZFP82 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000141883 357 2199 ATF1 ZNF133 ARID4B DMAP1 ZNF2 ZNF121 ZNF416 ZNF143 KLF7 SP3

Genomic Location for ZFP82 Gene

Chromosome:
19
Start:
36,383,120 bp from pter
End:
36,418,658 bp from pter
Size:
35,539 bases
Orientation:
Minus strand

Genomic View for ZFP82 Gene

Genes around ZFP82 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZFP82 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZFP82 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP82 Gene

Proteins for ZFP82 Gene

  • Protein details for ZFP82 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N141-ZFP82_HUMAN
    Recommended name:
    Zinc finger protein 82 homolog
    Protein Accession:
    Q8N141
    Secondary Accessions:
    • Q8NC63
    • Q8TF53

    Protein attributes for ZFP82 Gene

    Size:
    532 amino acids
    Molecular mass:
    62578 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB85534.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAB85534.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

neXtProt entry for ZFP82 Gene

Post-translational modifications for ZFP82 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZFP82 Gene

No data available for DME Specific Peptides for ZFP82 Gene

Domains & Families for ZFP82 Gene

Gene Families for ZFP82 Gene

Protein Domains for ZFP82 Gene

Suggested Antigen Peptide Sequences for ZFP82 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N141

UniProtKB/Swiss-Prot:

ZFP82_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZFP82: view

Function for ZFP82 Gene

Molecular function for ZFP82 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZFP82 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZFP82: view
genes like me logo Genes that share phenotypes with ZFP82: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZFP82 Gene

Localization for ZFP82 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP82 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZFP82 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZFP82 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZFP82: view

Pathways & Interactions for ZFP82 Gene

SuperPathways for ZFP82 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZFP82 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZFP82: view

No data available for Pathways by source and SIGNOR curated interactions for ZFP82 Gene

Transcripts for ZFP82 Gene

Unigene Clusters for ZFP82 Gene

ZFP82 zinc finger protein:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP82 Gene

No ASD Table

Relevant External Links for ZFP82 Gene

GeneLoc Exon Structure for
ZFP82
ECgene alternative splicing isoforms for
ZFP82

Expression for ZFP82 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZFP82 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZFP82 Gene:

ZFP82

SOURCE GeneReport for Unigene cluster for ZFP82 Gene:

Hs.558734
genes like me logo Genes that share expression patterns with ZFP82: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZFP82 Gene

Orthologs for ZFP82 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZFP82 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZFP82 34 35
  • 99.56 (n)
cow
(Bos Taurus)
Mammalia ZFP82 34
  • 91.54 (n)
dog
(Canis familiaris)
Mammalia ZFP82 34 35
  • 91.22 (n)
mouse
(Mus musculus)
Mammalia Zfp82 34 16 35
  • 82.33 (n)
rat
(Rattus norvegicus)
Mammalia LOC102547241 34
  • 80.42 (n)
Species where no ortholog for ZFP82 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZFP82 Gene

ENSEMBL:
Gene Tree for ZFP82 (if available)
TreeFam:
Gene Tree for ZFP82 (if available)

Paralogs for ZFP82 Gene

(502) SIMAP similar genes for ZFP82 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZFP82: view

Variants for ZFP82 Gene

Sequence variations from dbSNP and Humsavar for ZFP82 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10402218 -- 36,386,922(+) agagc(A/G)agact intron-variant
rs10403466 -- 36,386,203(+) tagag(G/T)gccct intron-variant
rs10409479 -- 36,414,727(+) AAGGC(A/C)CCTGT intron-variant
rs10412442 -- 36,409,745(+) CCTTA(A/G)CATGA intron-variant
rs10414054 -- 36,413,923(+) tgaga(C/T)gcagt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZFP82 Gene

Variant ID Type Subtype PubMed ID
esv3644256 CNV gain 21293372
nsv1066026 CNV gain 25217958
nsv1067101 CNV gain 25217958
nsv1114003 CNV deletion 24896259
nsv833816 CNV gain 17160897

Variation tolerance for ZFP82 Gene

Residual Variation Intolerance Score: 20.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.61; 13.10% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZFP82 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZFP82

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZFP82 Gene

Disorders for ZFP82 Gene

Relevant External Links for ZFP82

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZFP82

No disorders were found for ZFP82 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZFP82 Gene

Publications for ZFP82 Gene

  1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Poor survival is associated with the methylated degree of zinc-finger protein 545 (ZNF545) DNA promoter in gastric cancer. (PMID: 25714013) Deng J. … Hao X. (Oncotarget 2015) 3 64
  5. Zinc-finger protein 545 inhibits cell proliferation as a tumor suppressor through inducing apoptosis and is disrupted by promoter methylation in breast cancer. (PMID: 25360542) Xiao Y. … Tao Q. (PLoS ONE 2014) 3 64

Products for ZFP82 Gene

Sources for ZFP82 Gene

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