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Aliases for ZFP82 Gene

Aliases for ZFP82 Gene

  • ZFP82 Zinc Finger Protein 2 3 5
  • Zinc Finger Protein 545 2 3 4
  • ZNF545 3 4
  • Zinc Finger Protein 82 Homolog (Mouse) 2
  • Zinc Finger Protein 82 2
  • Zinc Finger Protein 85 3
  • KIAA1948 4
  • Zfp-82 4

External Ids for ZFP82 Gene

Previous HGNC Symbols for ZFP82 Gene

  • ZNF545

Previous GeneCards Identifiers for ZFP82 Gene

  • GC19M041577
  • GC19M036874
  • GC19M036882
  • GC19M033351
  • GC19M036417
  • GC19M036698

Summaries for ZFP82 Gene

GeneCards Summary for ZFP82 Gene

ZFP82 (ZFP82 Zinc Finger Protein) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF345.

UniProtKB/Swiss-Prot for ZFP82 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFP82 Gene

Genomics for ZFP82 Gene

Regulatory Elements for ZFP82 Gene

Enhancers for ZFP82 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZFP82 on UCSC Golden Path with GeneCards custom track

Promoters for ZFP82 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZFP82 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZFP82 Gene

Chromosome:
19
Start:
36,383,120 bp from pter
End:
36,418,658 bp from pter
Size:
35,539 bases
Orientation:
Minus strand

Genomic View for ZFP82 Gene

Genes around ZFP82 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZFP82 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZFP82 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP82 Gene

Proteins for ZFP82 Gene

  • Protein details for ZFP82 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N141-ZFP82_HUMAN
    Recommended name:
    Zinc finger protein 82 homolog
    Protein Accession:
    Q8N141
    Secondary Accessions:
    • Q8NC63
    • Q8TF53

    Protein attributes for ZFP82 Gene

    Size:
    532 amino acids
    Molecular mass:
    62578 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB85534.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAB85534.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

neXtProt entry for ZFP82 Gene

Proteomics data for ZFP82 Gene at MOPED

Post-translational modifications for ZFP82 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZFP82 Gene

Antibody Products

No data available for DME Specific Peptides for ZFP82 Gene

Domains & Families for ZFP82 Gene

Gene Families for ZFP82 Gene

Protein Domains for ZFP82 Gene

Suggested Antigen Peptide Sequences for ZFP82 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N141

UniProtKB/Swiss-Prot:

ZFP82_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZFP82: view

Function for ZFP82 Gene

Molecular function for ZFP82 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZFP82: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZFP82 Gene

Localization for ZFP82 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP82 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZFP82 Gene COMPARTMENTS Subcellular localization image for ZFP82 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZFP82 Gene

Pathways & Interactions for ZFP82 Gene

SuperPathways for ZFP82 Gene

No Data Available

Interacting Proteins for ZFP82 Gene

Gene Ontology (GO) - Biological Process for ZFP82 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZFP82 Gene

Drugs & Compounds for ZFP82 Gene

No Compound Related Data Available

Transcripts for ZFP82 Gene

Unigene Clusters for ZFP82 Gene

ZFP82 zinc finger protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP82 Gene

No ASD Table

Relevant External Links for ZFP82 Gene

GeneLoc Exon Structure for
ZFP82
ECgene alternative splicing isoforms for
ZFP82

Expression for ZFP82 Gene

mRNA expression in normal human tissues for ZFP82 Gene

SOURCE GeneReport for Unigene cluster for ZFP82 Gene Hs.558734

genes like me logo Genes that share expression patterns with ZFP82: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZFP82 Gene

Orthologs for ZFP82 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZFP82 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZFP82 35
  • 91.54 (n)
  • 92.18 (a)
dog
(Canis familiaris)
Mammalia ZFP82 35
  • 91.22 (n)
  • 93.18 (a)
ZFP82 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp82 35
  • 82.33 (n)
  • 85.6 (a)
Zfp82 16
Zfp82 36
  • 85 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZFP82 35
  • 99.56 (n)
  • 100 (a)
ZFP82 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC102547241 35
  • 80.42 (n)
  • 84.6 (a)
Species with no ortholog for ZFP82:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZFP82 Gene

ENSEMBL:
Gene Tree for ZFP82 (if available)
TreeFam:
Gene Tree for ZFP82 (if available)

Paralogs for ZFP82 Gene

(502) SIMAP similar genes for ZFP82 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZFP82: view

Variants for ZFP82 Gene

Sequence variations from dbSNP and Humsavar for ZFP82 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7256914 -- 36,406,187(+) TATTA(C/T)TTCTT intron-variant
rs7257783 -- 36,416,586(+) ACCCC(A/G)TCTCT intron-variant
rs7259288 -- 36,410,514(+) tttgt(G/T)ttttt intron-variant
rs7351095 -- 36,412,723(+) TATAA(A/G)GCACA intron-variant
rs12976881 -- 36,396,296(+) aagat(C/T)tcttc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZFP82 Gene

Variant ID Type Subtype PubMed ID
nsv833816 CNV Gain 17160897

Variation tolerance for ZFP82 Gene

Residual Variation Intolerance Score: 20.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.61; 13.10% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZFP82 Gene

Disorders for ZFP82 Gene

Relevant External Links for ZFP82

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZFP82

No disorders were found for ZFP82 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZFP82 Gene

Publications for ZFP82 Gene

  1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4 67
  2. Poor survival is associated with the methylated degree of zinc-finger protein 545 (ZNF545) DNA promoter in gastric cancer. (PMID: 25714013) Deng J. … Hao X. (Oncotarget 2015) 3
  3. Zinc-finger protein 545 inhibits cell proliferation as a tumor suppressor through inducing apoptosis and is disrupted by promoter methylation in breast cancer. (PMID: 25360542) Xiao Y. … Tao Q. (PLoS ONE 2014) 3
  4. Zinc-finger protein 545 is a novel tumour suppressor that acts by inhibiting ribosomal RNA transcription in gastric cancer. (PMID: 22580414) Wang S. … Yu J. (Gut 2013) 3
  5. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3

Products for ZFP82 Gene

Sources for ZFP82 Gene

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