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Aliases for ZFP69B Gene

Aliases for ZFP69B Gene

  • ZFP69 Zinc Finger Protein B 2 3 5
  • Zinc Finger Protein 643 2 3 4
  • ZNF643 3 4
  • Novel Zinc Finger Protein 3
  • ZKSCAN23B 3
  • ZSCAN54B 3

External Ids for ZFP69B Gene

Previous HGNC Symbols for ZFP69B Gene

  • ZNF643

Previous GeneCards Identifiers for ZFP69B Gene

  • GC01P040916

Summaries for ZFP69B Gene

GeneCards Summary for ZFP69B Gene

ZFP69B (ZFP69 Zinc Finger Protein B) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF514.

UniProtKB/Swiss-Prot for ZFP69B Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFP69B Gene

Genomics for ZFP69B Gene

Regulatory Elements for ZFP69B Gene

Enhancers for ZFP69B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZFP69B on UCSC Golden Path with GeneCards custom track

Promoters for ZFP69B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZFP69B on UCSC Golden Path with GeneCards custom track

Genomic Location for ZFP69B Gene

40,450,086 bp from pter
40,463,718 bp from pter
13,633 bases
Plus strand

Genomic View for ZFP69B Gene

Genes around ZFP69B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZFP69B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZFP69B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP69B Gene

Proteins for ZFP69B Gene

  • Protein details for ZFP69B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein ZFP69B
    Protein Accession:
    Secondary Accessions:
    • Q5QPL4

    Protein attributes for ZFP69B Gene

    534 amino acids
    Molecular mass:
    61481 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH17498.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI19856.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZFP69B Gene


neXtProt entry for ZFP69B Gene

Proteomics data for ZFP69B Gene at MOPED

Post-translational modifications for ZFP69B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZFP69B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZFP69B Gene

Domains & Families for ZFP69B Gene

Gene Families for ZFP69B Gene

Protein Domains for ZFP69B Gene

Suggested Antigen Peptide Sequences for ZFP69B Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZFP69B: view

Function for ZFP69B Gene

Molecular function for ZFP69B Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZFP69B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZFP69B: view
genes like me logo Genes that share phenotypes with ZFP69B: view

Animal Model Products

CRISPR Products

miRNA for ZFP69B Gene

miRTarBase miRNAs that target ZFP69B

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZFP69B Gene

Localization for ZFP69B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP69B Gene

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZFP69B Gene

Pathways & Interactions for ZFP69B Gene

SuperPathways for ZFP69B Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZFP69B: view

Pathways by source for ZFP69B Gene

2 Reactome pathways for ZFP69B Gene

Interacting Proteins for ZFP69B Gene

Gene Ontology (GO) - Biological Process for ZFP69B Gene


No data available for SIGNOR curated interactions for ZFP69B Gene

Drugs & Compounds for ZFP69B Gene

No Compound Related Data Available

Transcripts for ZFP69B Gene

mRNA/cDNA for ZFP69B Gene

Unigene Clusters for ZFP69B Gene

ZFP69 zinc finger protein B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP69B Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
SP2: - -
SP4: -

Relevant External Links for ZFP69B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZFP69B Gene

mRNA expression in normal human tissues for ZFP69B Gene

SOURCE GeneReport for Unigene cluster for ZFP69B Gene Hs.133034

genes like me logo Genes that share expression patterns with ZFP69B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZFP69B Gene

Orthologs for ZFP69B Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZFP69B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZFP69B 35
  • 87.85 (n)
  • 83.18 (a)
-- 36
  • 16 (a)
(Canis familiaris)
Mammalia ZNF643 35
  • 89.58 (n)
  • 87.38 (a)
ZFP69B 36
  • 87 (a)
(Pan troglodytes)
Mammalia ZNF643 35
  • 99 (n)
  • 98.88 (a)
ZFP69B 36
  • 99 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 42 (a)
Species with no ortholog for ZFP69B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZFP69B Gene

Gene Tree for ZFP69B (if available)
Gene Tree for ZFP69B (if available)

Paralogs for ZFP69B Gene

Paralogs for ZFP69B Gene

(457) SIMAP similar genes for ZFP69B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZFP69B: view

Variants for ZFP69B Gene

Sequence variations from dbSNP and Humsavar for ZFP69B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs2272994 - 40,457,347(+) AGGAT(A/G)TCAGC reference, missense
rs12407929 - 40,463,059(+) ATACC(A/G)GGGAA reference, missense
rs169698 -- 40,458,825(+) CTGGA(A/G)AAATT intron-variant
rs182350 -- 40,458,871(+) ATTCA(A/G)AAAGA intron-variant
rs184100 -- 40,458,890(+) CCTTG(G/T)GGCTC intron-variant

Variation tolerance for ZFP69B Gene

Residual Variation Intolerance Score: 89.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.16; 80.78% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for ZFP69B Gene

Disorders for ZFP69B Gene

Relevant External Links for ZFP69B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZFP69B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZFP69B Gene

Publications for ZFP69B Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. (PMID: 25963833) Drissi R. … Boisvert F.M. (Mol. Cell Proteomics 2015) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3

Products for ZFP69B Gene

Sources for ZFP69B Gene