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Aliases for ZFP69B Gene

Aliases for ZFP69B Gene

  • ZFP69 Zinc Finger Protein B 2 3
  • Zinc Finger Protein 643 2 3 4
  • ZNF643 3 4
  • Zinc Finger Protein ZFP69B 3
  • Novel Zinc Finger Protein 3
  • ZKSCAN23B 3
  • ZSCAN54B 3

External Ids for ZFP69B Gene

Previous Symbols for ZFP69B Gene

  • ZNF643

Summaries for ZFP69B Gene

GeneCards Summary for ZFP69B Gene

ZFP69B (ZFP69 Zinc Finger Protein B) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZFP69.

UniProtKB/Swiss-Prot for ZFP69B Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFP69B Gene

Genomics for ZFP69B Gene

Genomic Location for ZFP69B Gene

Start:
40,450,102 bp from pter
End:
40,463,718 bp from pter
Size:
13,617 bases
Orientation:
Plus strand

Genomic View for ZFP69B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZFP69B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP69B Gene

No data available for Regulatory Elements for ZFP69B Gene

Proteins for ZFP69B Gene

  • Protein details for ZFP69B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UJL9-ZF69B_HUMAN
    Recommended name:
    Zinc finger protein ZFP69B
    Protein Accession:
    Q9UJL9
    Secondary Accessions:
    • Q5QPL4

    Protein attributes for ZFP69B Gene

    Size:
    534 amino acids
    Molecular mass:
    61481 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH17498.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI19856.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZFP69B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZFP69B Gene

Proteomics data for ZFP69B Gene at MOPED

Post-translational modifications for ZFP69B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZFP69B Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZFP69B Gene

Domains for ZFP69B Gene

Gene Families for ZFP69B Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZFP69B Gene

Graphical View of Domain Structure for InterPro Entry

Q9UJL9

UniProtKB/Swiss-Prot:

ZF69B_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q9UJL9
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9UJL9
Similarity:
  • Contains 9 C2H2-type zinc fingers.:
    • Q9UJL9
genes like me logo Genes that share domains with ZFP69B: view

No data available for Suggested Antigen Peptide Sequences for ZFP69B Gene

Function for ZFP69B Gene

Molecular function for ZFP69B Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZFP69B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZFP69B: view

Phenotypes for ZFP69B Gene

GenomeRNAi human phenotypes for ZFP69B:
genes like me logo Genes that share phenotypes with ZFP69B: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZFP69B Gene

Localization for ZFP69B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP69B Gene

Gene Ontology (GO) - Cellular Components for ZFP69B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZFP69B: view

No data available for Subcellular locations from COMPARTMENTS for ZFP69B Gene

Pathways for ZFP69B Gene

SuperPathways for ZFP69B Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZFP69B: view

Pathways by source for ZFP69B Gene

2 Reactome pathways for ZFP69B Gene

Interacting Proteins for ZFP69B Gene

Gene Ontology (GO) - Biological Process for ZFP69B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZFP69B: view

Transcripts for ZFP69B Gene

mRNA/cDNA for ZFP69B Gene

Unigene Clusters for ZFP69B Gene

ZFP69 zinc finger protein B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP69B Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
SP1:
SP2: - -
SP3:
SP4: -

Relevant External Links for ZFP69B Gene

GeneLoc Exon Structure for
ZFP69B
ECgene alternative splicing isoforms for
ZFP69B

Expression for ZFP69B Gene

mRNA expression in normal human tissues for ZFP69B Gene

SOURCE GeneReport for Unigene cluster for ZFP69B Gene Hs.133034

genes like me logo Genes that share expressions with ZFP69B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZFP69B Gene

Orthologs for ZFP69B Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZFP69B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZFP69B 36
  • 99 (a)
OneToOne
ZNF643 35
  • 99 (n)
  • 98.88 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 16 (a)
ManyToMany
ZFP69B 35
  • 87.85 (n)
  • 83.18 (a)
dog
(Canis familiaris)
Mammalia ZFP69B 36
  • 87 (a)
OneToOne
ZNF643 35
  • 89.58 (n)
  • 87.38 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 42 (a)
OneToMany
Species with no ortholog for ZFP69B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZFP69B Gene

ENSEMBL:
Gene Tree for ZFP69B (if available)
TreeFam:
Gene Tree for ZFP69B (if available)

Paralogs for ZFP69B Gene

Paralogs for ZFP69B Gene

Selected SIMAP similar genes for ZFP69B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZFP69B: view

Variants for ZFP69B Gene

Sequence variations from dbSNP and Humsavar for ZFP69B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs169698 -- 40,458,825(+) CTGGA(A/G)AAATT intron-variant
rs182350 -- 40,458,871(+) ATTCA(A/G)AAAGA intron-variant
rs184100 -- 40,458,890(+) CCTTG(G/T)GGCTC intron-variant
rs209607 -- 40,450,546(+) CACCG(C/T)CTCCG upstream-variant-2KB, intron-variant
rs209608 -- 40,454,660(+) CCAAA(A/G)TGCTG intron-variant

Relevant External Links for ZFP69B Gene

HapMap Linkage Disequilibrium report
ZFP69B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZFP69B Gene

Disorders for ZFP69B Gene

No disorders were found for ZFP69B Gene.

No data available for UniProtKB/Swiss-Prot for ZFP69B Gene

Publications for ZFP69B Gene

  1. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZFP69B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZFP69B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZFP69B
    • Block miRNA regulation of ZFP69B using miScript Target Protectors

    Sources for ZFP69B Gene

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