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Aliases for ZFP69 Gene

Aliases for ZFP69 Gene

  • ZFP69 Zinc Finger Protein 2 3
  • Zinc Finger Protein 642 2 3 4
  • ZFP69 Zinc Finger Protein A 2 3
  • ZNF642 3 4
  • Zinc Finger Protein ZFP69 3
  • ZKSCAN23A 3
  • ZSCAN54A 3
  • ZFP69A 3

External Ids for ZFP69 Gene

Previous Symbols for ZFP69 Gene

  • ZNF642

Summaries for ZFP69 Gene

GeneCards Summary for ZFP69 Gene

ZFP69 (ZFP69 Zinc Finger Protein) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZFP69B.

UniProtKB/Swiss-Prot for ZFP69 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFP69 Gene

Genomics for ZFP69 Gene

Genomic Location for ZFP69 Gene

Start:
40,477,215 bp from pter
End:
40,496,343 bp from pter
Size:
19,129 bases
Orientation:
Plus strand

Genomic View for ZFP69 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZFP69 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP69 Gene

No data available for Regulatory Elements for ZFP69 Gene

Proteins for ZFP69 Gene

  • Protein details for ZFP69 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q49AA0-ZFP69_HUMAN
    Recommended name:
    Zinc finger protein ZFP69
    Protein Accession:
    Q49AA0
    Secondary Accessions:
    • Q5SWM5
    • Q6ZWK8

    Protein attributes for ZFP69 Gene

    Size:
    526 amino acids
    Molecular mass:
    61181 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC85492.1; Type=Erroneous termination; Positions=506; Note=Translated as Tyr.; Evidence={ECO:0000305};

neXtProt entry for ZFP69 Gene

Proteomics data for ZFP69 Gene at MOPED

Post-translational modifications for ZFP69 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZFP69 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZFP69 Gene

Domains for ZFP69 Gene

Gene Families for ZFP69 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZFP69 Gene

Graphical View of Domain Structure for InterPro Entry

Q49AA0

UniProtKB/Swiss-Prot:

ZFP69_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q49AA0
  • Contains 1 SCAN box domain.:
    • Q49AA0
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q49AA0
Similarity:
  • Contains 9 C2H2-type zinc fingers.:
    • Q49AA0
genes like me logo Genes that share domains with ZFP69: view

No data available for Suggested Antigen Peptide Sequences for ZFP69 Gene

Function for ZFP69 Gene

Molecular function for ZFP69 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZFP69 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZFP69: view

Phenotypes for ZFP69 Gene

GenomeRNAi human phenotypes for ZFP69:
genes like me logo Genes that share phenotypes with ZFP69: view

miRNA for ZFP69 Gene

miRTarBase miRNAs that target ZFP69

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZFP69 Gene

Localization for ZFP69 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP69 Gene

Gene Ontology (GO) - Cellular Components for ZFP69 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZFP69: view

No data available for Subcellular locations from COMPARTMENTS for ZFP69 Gene

Pathways for ZFP69 Gene

SuperPathways for ZFP69 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZFP69: view

Pathways by source for ZFP69 Gene

2 Reactome pathways for ZFP69 Gene

Interacting Proteins for ZFP69 Gene

Gene Ontology (GO) - Biological Process for ZFP69 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZFP69: view

Transcripts for ZFP69 Gene

mRNA/cDNA for ZFP69 Gene

Unigene Clusters for ZFP69 Gene

ZFP69 zinc finger protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP69 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b
SP1: - -
SP2: - - -
SP3:
SP4:

Relevant External Links for ZFP69 Gene

GeneLoc Exon Structure for
ZFP69
ECgene alternative splicing isoforms for
ZFP69

Expression for ZFP69 Gene

mRNA expression in normal human tissues for ZFP69 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZFP69 Gene

SOURCE GeneReport for Unigene cluster for ZFP69 Gene Hs.434385

genes like me logo Genes that share expressions with ZFP69: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZFP69 Gene

Orthologs for ZFP69 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZFP69 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF642 35
  • 99.75 (n)
  • 99.24 (a)
ZNF642 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZFP69 35
  • 89.93 (n)
  • 87.57 (a)
ZFP69 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 11 (a)
ManyToMany
ZNF642 35
  • 89.25 (n)
  • 88.68 (a)
mouse
(Mus musculus)
Mammalia Zfp69 35
  • 78.21 (n)
  • 75.27 (a)
Zfp69 16
Zfp69 36
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 40 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zfp69 35
  • 79.46 (n)
  • 76.16 (a)
Species with no ortholog for ZFP69:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZFP69 Gene

ENSEMBL:
Gene Tree for ZFP69 (if available)
TreeFam:
Gene Tree for ZFP69 (if available)

Paralogs for ZFP69 Gene

Paralogs for ZFP69 Gene

Selected SIMAP similar genes for ZFP69 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZFP69: view

Variants for ZFP69 Gene

Sequence variations from dbSNP and Humsavar for ZFP69 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs3795348 -- 40,495,777(-) CCAGT(A/G)TGGAT synonymous-codon, reference
rs4076058 -- 40,479,350(-) TGCCT(C/T)ACTGG utr-variant-5-prime
rs4291490 -- 40,477,484(+) CCGCC(A/G)GCCCC upstream-variant-2KB, utr-variant-5-prime
rs4660411 -- 40,488,253(+) TTAAG(A/G)TGAGG intron-variant
rs5773698 -- 40,478,149(+) CACAC(-/AC)GCCTA intron-variant, upstream-variant-2KB

Relevant External Links for ZFP69 Gene

HapMap Linkage Disequilibrium report
ZFP69
Human Gene Mutation Database (HGMD)
ZFP69

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZFP69 Gene

Disorders for ZFP69 Gene

No disorders were found for ZFP69 Gene.

No data available for UniProtKB/Swiss-Prot for ZFP69 Gene

Publications for ZFP69 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  4. Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL. (PMID: 19578398) Scherneck S. … Joost H.G. (PLoS Genet. 2009) 3
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for ZFP69 Gene

Sources for ZFP69 Gene

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