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Aliases for ZFP64 Gene

Aliases for ZFP64 Gene

  • ZFP64 Zinc Finger Protein 2 3
  • Zinc Finger Protein 338 2 3 4
  • Zinc Finger Protein 64 2 3
  • ZNF338 3 4
  • Zinc Finger Protein 64 Homolog (Mouse) 2
  • Zinc Finger Protein 64 Homolog 3
  • Zfp-64 4

External Ids for ZFP64 Gene

Previous Symbols for ZFP64 Gene

  • ZNF338

Summaries for ZFP64 Gene

GeneCards Summary for ZFP64 Gene

ZFP64 (ZFP64 Zinc Finger Protein) is a Protein Coding gene. An important paralog of this gene is HINFP.

UniProtKB/Swiss-Prot for ZFP64 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZFP64 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFP64 Gene

Genomics for ZFP64 Gene

Genomic Location for ZFP64 Gene

Start:
52,051,663 bp from pter
End:
52,204,308 bp from pter
Size:
152,646 bases
Orientation:
Minus strand

Genomic View for ZFP64 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZFP64 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP64 Gene

Regulatory Elements for ZFP64 Gene

Proteins for ZFP64 Gene

  • Protein details for ZFP64 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NPA5-ZF64A_HUMAN
    Recommended name:
    Zinc finger protein 64 homolog, isoforms 1 and 2
    Protein Accession:
    Q9NPA5
    Secondary Accessions:
    • Q9NTS7
    • Q9NVH4

    Protein attributes for ZFP64 Gene

    Size:
    681 amino acids
    Molecular mass:
    74644 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZFP64 Gene

    Alternative splice isoforms for ZFP64 Gene

    UniProtKB/Swiss-Prot:
  • Protein details for ZFP64 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NTW7-ZF64B_HUMAN
    Recommended name:
    Zinc finger protein 64 homolog, isoforms 3 and 4
    Protein Accession:
    Q9NTW7
    Secondary Accessions:
    • A2A2N4
    • Q53H69
    • Q53XQ1
    • Q5JWM0
    • Q5JWM1
    • Q8WU98
    • Q9H9P1

    Protein attributes for ZFP64 Gene

    Size:
    645 amino acids
    Molecular mass:
    72217 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZFP64 Gene

neXtProt entry for ZFP64 Gene

Proteomics data for ZFP64 Gene at MOPED

Post-translational modifications for ZFP64 Gene

No data available for DME Specific Peptides for ZFP64 Gene

Domains for ZFP64 Gene

Gene Families for ZFP64 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZFP64 Gene

UniProtKB/Swiss-Prot:

ZF64B_HUMAN
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9NPA5
    • Q9NTW7
Similarity:
  • Contains 9 C2H2-type zinc fingers.:
    • Q9NPA5
  • Contains 13 C2H2-type zinc fingers.:
    • Q9NTW7
genes like me logo Genes that share domains with ZFP64: view

Function for ZFP64 Gene

Molecular function for ZFP64 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZFP64 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZFP64: view
genes like me logo Genes that share phenotypes with ZFP64: view

miRNA for ZFP64 Gene

miRTarBase miRNAs that target ZFP64

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZFP64 Gene

Localization for ZFP64 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP64 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZFP64 Gene COMPARTMENTS Subcellular localization image for ZFP64 gene
Compartment Confidence
nucleus 4
cytosol 1

Gene Ontology (GO) - Cellular Components for ZFP64 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZFP64: view

Pathways for ZFP64 Gene

SuperPathways for ZFP64 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZFP64 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0048026 positive regulation of mRNA splicing, via spliceosome IEA --
genes like me logo Genes that share ontologies with ZFP64: view

No data available for Pathways by source for ZFP64 Gene

Compounds for ZFP64 Gene

(1) HMDB Compounds for ZFP64 Gene

Compound Synonyms Cas Number PubMed IDs
Zinc
  • Zinc
7440-66-6
genes like me logo Genes that share compounds with ZFP64: view

Transcripts for ZFP64 Gene

Unigene Clusters for ZFP64 Gene

ZFP64 zinc finger protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP64 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^
SP1: - - - - - - - -
SP2: - - - - - - -
SP3: - - - -
SP4: - - - - -
SP5: - - - -
SP6: - - - - - - -
SP7: - -
SP8: - - -
SP9: - - -
SP10: - - - - - - -
SP11: - - -
SP12: - - - - - - - - - - -
SP13:
SP14:
SP15: - - - -
SP16: -
SP17:

ExUns: 13a · 13b ^ 14 ^ 15a · 15b ^ 16a · 16b
SP1: -
SP2:
SP3:
SP4:
SP5:
SP6:
SP7: -
SP8:
SP9:
SP10:
SP11:
SP12:
SP13: -
SP14:
SP15:
SP16:
SP17:

Relevant External Links for ZFP64 Gene

GeneLoc Exon Structure for
ZFP64
ECgene alternative splicing isoforms for
ZFP64

Expression for ZFP64 Gene

mRNA expression in normal human tissues for ZFP64 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZFP64 Gene

SOURCE GeneReport for Unigene cluster for ZFP64 Gene Hs.473082

genes like me logo Genes that share expressions with ZFP64: view

Orthologs for ZFP64 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZFP64 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZFP64 36
  • 99.41 (n)
  • 99.26 (a)
ZFP64 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZFP64 36
  • 87.12 (n)
  • 89.23 (a)
ZFP64 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZFP64 36
  • 91.36 (n)
  • 95.43 (a)
ZFP64 37
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp64 36
  • 85.11 (n)
  • 87.72 (a)
Zfp64 16
Zfp64 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZFP64 37
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZFP64 37
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp64 36
  • 84.76 (n)
  • 88.2 (a)
chicken
(Gallus gallus)
Aves ZFP64 36
  • 73.05 (n)
  • 74.82 (a)
ZFP64 37
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZFP64 37
  • 69 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.3425 36
zfp64 36
  • 62.07 (n)
  • 56.9 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7584 36
zebrafish
(Danio rerio)
Actinopterygii zfp64 36
  • 57.27 (n)
  • 51.06 (a)
zfp64 37
  • 43 (a)
OneToOne
Species with no ortholog for ZFP64:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZFP64 Gene

ENSEMBL:
Gene Tree for ZFP64 (if available)
TreeFam:
Gene Tree for ZFP64 (if available)

Paralogs for ZFP64 Gene

Paralogs for ZFP64 Gene

Selected SIMAP similar genes for ZFP64 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZFP64 Gene

genes like me logo Genes that share paralogs with ZFP64: view

Variants for ZFP64 Gene

Sequence variations from dbSNP and Humsavar for ZFP64 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs747891 -- 52,168,077(-) CCTGC(C/T)AAATG intron-variant
rs927121 -- 52,193,427(+) CTAGC(C/T)GCTGG upstream-variant-2KB
rs973341 -- 52,089,045(+) CTCCC(C/T)CTAGG intron-variant
rs1010144 -- 52,178,314(-) gaacc(A/G)ggtct intron-variant
rs1033696 -- 52,183,443(+) CCTCA(C/T)GAAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZFP64 Gene

Variant ID Type Subtype PubMed ID
nsv912928 CNV Gain 21882294
esv999399 CNV Insertion 20482838
esv995025 CNV Deletion 20482838
esv2532221 CNV Deletion 19546169
esv2065897 CNV Deletion 18987734
esv2722522 CNV Deletion 23290073
esv2676181 CNV Deletion 23128226
nsv179098 CNV Loss 16902084
esv24606 CNV Loss 19812545
esv1009237 CNV Loss 20482838
nsv514942 CNV Loss 21397061
esv32674 CNV Gain 17666407
esv3942 CNV Deletion 18987735
nsv179831 CNV Loss 16902084
esv2670525 CNV Deletion 23128226

Relevant External Links for ZFP64 Gene

HapMap Linkage Disequilibrium report
ZFP64

Disorders for ZFP64 Gene

Relevant External Links for ZFP64

Genetic Association Database (GAD)
ZFP64
Human Genome Epidemiology (HuGE) Navigator
ZFP64
genes like me logo Genes that share disorders with ZFP64: view

No data available for UniProtKB/Swiss-Prot for ZFP64 Gene

Publications for ZFP64 Gene

  1. Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. (PMID: 17362836) Schymick J.C. … Traynor B.J. (Lancet Neurol 2007) 3 49
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A search for a mammalian homologue of the Drosophila photoreceptor development gene glass yields Zfp64, a zinc finger encoding gene which maps to the distal end of mouse chromosome 2. (PMID: 9034307) Mack H.G. … Bowtell D.D. (Gene 1997) 2 3
  5. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4

Products for ZFP64 Gene

Sources for ZFP64 Gene

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