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ZFP62 Gene

protein-coding   GIFtS: 48
GCID: GC05M180274

ZFP62 Zinc Finger Protein

(Previous names: zinc finger protein 62 homolog (mouse), zinc finger protein...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
ZFP62 Zinc Finger Protein1 2     ZNF7552
Zinc Finger Protein 621     zfp-622
Zinc Finger Protein 62 Homolog (Mouse)1     Zinc Finger Protein 62 Homolog2
ZET2     Zfp-623

External Ids:    HGNC: 232411   Entrez Gene: 6438362   Ensembl: ENSG000001966707   OMIM: 6102815   UniProtKB: Q8NB503   
ORGUL members:         

Export aliases for ZFP62 gene to outside databases

Previous GC identifers: GC05M180338 GC05M180385 GC05M9A0012 GC05M9B0012 GC05M180209 GC05M174999


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZFP62 Gene:
ZFP62 (ZFP62 zinc finger protein) is a protein-coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF616.

UniProtKB/Swiss-Prot: ZFP62_HUMAN, Q8NB50
Function: May play a role in differentiating skeletal muscle (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NT_023133.14  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZFP62 gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B3   oct-B2   NF-kappaB   POU2F2   POU2F1   POU2F1a   Chx10   NF-kappaB1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ZFP62

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZFP62


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.3   Ensembl cytogenetic band:  5q35.3   HGNC cytogenetic band: 5q35.3

ZFP62 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZFP62 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M180274:  view genomic region     (about GC identifiers)

Start:
180,274,611 bp from pter      End:
180,288,286 bp from pter
Size:
13,676 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ZFP62_HUMAN, Q8NB50 (See protein sequence)
Recommended Name: Zinc finger protein 62 homolog  
Size: 900 amino acids; 102511 Da
Sequence caution: Sequence=AAI40762.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAC03691.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAG58558.1;
Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical GTG
valine codon; Sequence=CAI46133.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B4DIP6 B4E0N3 B5MDX6 B7ZVZ2 B9EIP6 E9PFT8 J3QTA9
Alternative splicing: 3 isoforms:  Q8NB50-1   Q8NB50-2   Q8NB50-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZFP62: NX_Q8NB50

Explore proteomics data for ZFP62 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys195, Lys198
  • Modification sites at PhosphoSitePlus

  • See ZFP62 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001166109.1  NP_689496.4  

    ENSEMBL proteins: 
     ENSP00000426193   ENSP00000423820   ENSP00000422987   ENSP00000423709   ENSP00000424156  
     ENSP00000352053  

    ZFP62 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZFP62

     
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    antibodies-online proteins for ZFP62 (5 products) 

     
    antibodies-online peptides for ZFP62

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    antibodies-online antibodies for ZFP62 (20 products) 

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    antibodies-online kits for ZFP62 (5 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q8NB50

    ProtoNet protein and cluster: Q8NB50

    1 Blocks protein domain: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: ZFP62_HUMAN, Q8NB50
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 23 C2H2-type zinc fingers


    Find genes that share domains with ZFP62           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZFP62_HUMAN, Q8NB50
    Function: May play a role in differentiating skeletal muscle (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZFP62           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Zfp62 (no phenotypes)

    Find genes that share phenotypes with ZFP62           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ZFP62

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZFP62:
    hsa-let-7e-5p (MIRT051621)

    Block miRNA regulation of human, mouse, rat ZFP62 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZFP62 (see all 16):
    hsa-miR-3938 hsa-miR-125a-5p hsa-miR-181c hsa-miR-181a-2* hsa-miR-1257 hsa-miR-125b hsa-miR-181b hsa-miR-18a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZFP62_HUMAN, Q8NB50: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    cytoskeleton1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ZFP62           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZFP62
    Interactions:

        Search GeneGlobe Interaction Network for ZFP62

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with ZFP62           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZFP62



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZFP62 gene (2 alternative transcripts): 
    NM_001172638.1  NM_152283.4  

    Unigene Cluster for ZFP62:

    ZFP62 zinc finger protein
    Hs.509227  [show with all ESTs]
    Unigene Representative Sequence: AL832408
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000506377(uc003mmm.4) ENST00000512132 ENST00000507843 ENST00000502412
    ENST00000504225 ENST00000506439 ENST00000509066 ENST00000359141(uc011dhe.2 uc011dhf.2 uc010jlk.3)

    miRNA
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    Block miRNA regulation of human, mouse, rat ZFP62 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZFP62 (see all 16):
    hsa-miR-3938 hsa-miR-125a-5p hsa-miR-181c hsa-miR-181a-2* hsa-miR-1257 hsa-miR-125b hsa-miR-181b hsa-miR-18a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector (see all 2): ZFP62 (NM_152283)
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      QuantiTect SYBR Green Assays in human, mouse, rat ZFP62
      QuantiFast Probe-based Assays in human, mouse, rat ZFP62

    Additional mRNA sequence: 

    AK002206.1 AK091376.1 AK091550.1 AK295714.1 AK303450.1 AL832408.1 BC029573.1 BC140761.1 
    BC171780.1 

    6 DOTS entries:

    DT.75162574  DT.210900  DT.120883399  DT.100000778  DT.120883394  DT.120883390 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZFP62 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAGCCAGCT
    ZFP62 Expression
    About this image


    ZFP62 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
    ZFP62 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZFP62 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.509227
        Custom PCR Arrays for ZFP62
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFP62

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for ZFP62 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp621 , 5 zinc finger protein 621, 5 87.47(n)1
    88.71(a)1
      11 (29.23 cM)5
    227201  NM_009562.21  NP_033588.21 
     492032925 


    ENSEMBL Gene Tree for ZFP62 (if available)
    TreeFam Gene Tree for ZFP62 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZFP62 gene
    ZNF6162  ZNF4732  ZNF1602  ZNF4932  ZNF5462  ZNF992  ZNF8362  ZNF7212  
    ZNF5942  ZNF8412  ZNF432  ZNF780B2  ZNF1972  ZNF1072  ZNF585A2  ZNF8082  
    ZNF3472  ZNF8452  ZNF585B2  ZNF6582  ZNF6292  ZNF6242  ZNF2682  ZNF8142  
    Selected SIMAP similar genes for ZFP62 using alignment to 5 protein entries:     ZFP62_HUMAN (see all proteins) (see all similar genes):
    ZNF826P    ZNF78L1    DKFZp762K012    ZFS-5    DKFZp666C237    ZSCAN16
    ZNF56    DKFZp686N14223    HZF30    HZF36    ZFS-4    ZNF818P
    ZFS-6    DKFZp686B16128    GLI4    ZNF232    ZNF24    ZNF485

    Find genes that share paralogs with ZFP62           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZFP62 (see all 359)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1127852981,2
    F--180274250(+) GAAGAG/ATCTAT 2 -- int11Minor allele frequency- A:0.50CSA 2
    rs171412051,2
    C,F,H--180274253(+) GAGTCT/AATTTT 2 -- int117Minor allele frequency- A:0.10NA NS EA CSA 2028
    rs339219881,2
    C--180274377(+) TCCCG-/CTAGTTA 2 -- int10--------
    rs2493151,2
    C,F,O,A,H--180274402(-) TGATCG/CTCGTT 2 -- int122Minor allele frequency- C:0.41NS EA NA CSA 2531
    rs1440930401,2
    C--180274525(+) CCCTCG/TCTGGT 2 -- int10--------
    rs2493141,2
    C,F,O,A,H--180274553(+) TACCCC/AACAAA 2 -- int118Minor allele frequency- A:0.34NS EA NA CSA WA 2221
    rs2493131,2
    C,A--180274565(+) ATCTGG/ACACAC 2 -- int16Minor allele frequency- A:0.43NA CSA WA 245
    rs170806951,2
    C,F,H--180274654(+) ACCTCG/ACCACA 2 -- ut3114Minor allele frequency- A:0.08NA NS EA CSA 1419
    rs1487451911,2
    C--180275075(+) AGTTCA/GTCTGA 2 -- ut310--------
    rs754473831,2
    C--180275111(+) AACTAA/GTGTAT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for ZFP62 (180274611 - 180288286 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for ZFP62:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv830566CNV Loss17160897
    dgv6n29CNV Loss16826518
    nsv820020CNV Loss19587683
    nsv428133CNV Gain18775914
    dgv1882e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZFP62
    DNA2.0 Custom Variant and Variant Library Synthesis for ZFP62

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610281    OMIM disorders: --


    Find genes that share disorders with ZFP62           About GenesLikeMe

    Genetic Association Database (GAD): ZFP62
    Human Genome Epidemiology (HuGE) Navigator: ZFP62 (1 document)

    Export disorders for ZFP62 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZFP62 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with ZFP62)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Differentiation dependent expression in muscle cells of ZT3, a novel zinc finger factor differentially expressed in embryonic and adult tissues. (PubMed id 8808410)1, 3 Polimeni M....BouchAc M. (Mech. Dev. 1996)
    4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross- validation of MS/MS and MS/MS/MS spectra. (PubMed id 17924679)1 Yu L.R.... Veenstra T.D. (J. Proteome Res. 2007)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 643836 HGNC: 23241 Ensembl:ENSG00000196670 euGenes: HUgn643836 ECgene: ZFP62
    H-InvDB: ZFP62

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZFP62 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZFP62 gene:
    Search GeneIP for patents involving ZFP62

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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