ZFP62 Gene
protein-coding GIFtS : 44
GCID: GC05 M180274
ZFP62 zinc finger protein (Previous names: zinc finger protein 62 homolog (mouse), zinc finger protein... )
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Aliasesfor ZFP62 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases ZFP62 Zinc Finger Protein 1 2 Zinc Finger Protein 62 Homolog (Mouse)1 ZET1 2 Zfp-623 ZNF7551 2 Zinc Finger Protein 62 Homolog2 FLJ342311 Zfp-623 Zinc Finger Protein 621
Export aliases for ZFP62 gene to outside databases Previous GC identifers: GC05M180338 GC05M180385 GC05M9A0012 GC05M9B0012 GC05M180209 GC05M174999
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Summariesfor ZFP62 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: ZFP62_HUMAN, Q8NB50 Function : May play a role in differentiating skeletal muscle (By similarity)
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Genomic Viewsfor ZFP62 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000005.9 NC_018916.1 NT_023133.13 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ZFP62 gene promoter: POU2F2 (Oct-2.1) Oct-B1 oct-B3 oct-B2 NF-kappaB POU2F2 POU2F1 POU2F1a Chx10 NF-kappaB1 Other transcription factors Search SABiosciences Chromatin IP Primers for ZFP62 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ZFP62
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 5q35.3 Ensembl cytogenetic band: 5q35.3 HGNC cytogenetic band: 5q35.3 ZFP62 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 5 GeneLoc Exon Structure
GeneLoc location for GC05M180274: view genomic region
(about GC identifiers )
Start:
180,274,611 bp from pter
End:
180,288,286 bp from pter
Size:
13,676 bases
Orientation:
minus strand
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Proteinsfor ZFP62 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: ZFP62_HUMAN, Q8NB50 (See
protein sequence )Recommended Name: Zinc finger protein 62 homolog Size : 900 amino acids; 102511 Da
Subcellular location : Nucleus (Potential)
Sequence caution : Sequence=AAI40762.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAC03691.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAG58558.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical GTG valine codon; Sequence=CAI46133.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions : B4DIP6 B4E0N3 B5MDX6 B7ZVZ2 B9EIP6 E9PFT8 J3QTA9Alternative splicing : 3 isoforms : Q8NB50-1 Q8NB50-2 Q8NB50-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZFP62: NX_Q8NB50 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q8NB50 ZFP62 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (2 alternative transcripts):
NP_001166109.1 NP_689496.4 ENSEMBL proteins: ENSP00000426193 ENSP00000423820 ENSP00000422987 ENSP00000423709 ENSP00000424156 ENSP00000352053 Human Recombinant Protein Products: Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view) : About this table
ZFP62 for ontologies About GeneDecksing ZFP62 Antibody Products: Assay Products for ZFP62:
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Protein
Domains / Familiesfor ZFP62 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
ZFP62 for domains About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q8NB50 ProtoNet protein and cluster: Q8NB50
1 Blocks protein family : IPB007086 C2H2-type zinc finger signature UniProtKB/Swiss-Prot: ZFP62_HUMAN, Q8NB50 Similarity : Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity : Contains 23 C2H2-type zinc fingers
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Functionfor ZFP62 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: ZFP62_HUMAN, Q8NB50 Function : May play a role in differentiating skeletal muscle (By similarity)
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ZFP62 (see all 5 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ZFP62OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): ZFP62 (NM_152283 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZFP62 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ZFP62
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFP62
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0003676 nucleic acid binding
IEA -- GO:0008270 zinc ion binding
IEA --
ZFP62 for ontologies About GeneDecksing
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Pathways & Interactionsfor ZFP62 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZFP62 Gene Ontology (GO): 2 biological process terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0006351 transcription, DNA-dependent
IEA -- GO:0006355 regulation of transcription, DNA-dependent
IEA --
ZFP62 for ontologies About GeneDecksing
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Drugs & Compoundsfor ZFP62 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for ZFP62 Search CenterWatch for drugs/clinical trials and news about ZFP62
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Transcriptsfor ZFP62 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ZFP62 gene (2 alternative transcripts): NM_001172638.1 NM_152283.4 Unigene Cluster for ZFP62:
ZFP62 zinc finger protein Hs.509227 [show with all ESTs ] Unigene Representative Sequence: AL832408 8 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000506377 (uc003mmm.4 ) ENST00000512132 ENST00000507843 ENST00000502412 ENST00000504225 ENST00000506439 ENST00000509066 ENST00000359141 (uc011dhe.2 uc011dhf.2 uc010jlk.3 )Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ZFP62 (see all 5 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ZFP62OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): ZFP62 (NM_152283 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZFP62 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ZFP62
Additional cDNA sequence: AK002206.1 AK091376.1 AK091550.1 AK295714.1 AK303450.1 AL832408.1 BC029573.1 BC140761.1 BC171780.1
6 DOTS entries : DT.75162574 DT.210900
DT.100000778 DT.120883399 DT.120883394 DT.120883390 GeneLoc Exon Structure
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Expression for ZFP62 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ZFP62 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AAAGCCAGCT
About this image ZFP62 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See ZFP62 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ZFP62 SOURCE GeneReport for Unigene cluster: Hs.509227 SABiosciences Custom PCR Arrays for ZFP62 Primer Products: Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat ZFP62 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ZFP62 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ZFP62 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFP62
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Orthologsfor ZFP62 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for ZFP62 gene from 3/16 species (see all 16 ) About this table
ENSEMBL Gene Tree for ZFP62 (if available)TreeFam Gene Tree for ZFP62 (if available)
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Paralogsfor ZFP62 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor ZFP62 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 5 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for ZFP62 (180274611 - 180288286 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 4 variations for ZFP62 4 CNVs : 3592 2094 2093 59254
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ZFP62
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Disorders
/ Diseasesfor ZFP62 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
ZFP62 for disorders About GeneDecksing
OMIM gene information: 610281
OMIM disorders : --1 disease for ZFP62 : About MalaCards oligohydramnios Human Genome Epidemiology (HuGE) Navigator: ZFP62 (1 document)Export disorders for ZFP62 gene to outside databases
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Publicationsfor ZFP62 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ZFP62 gene, integrated from 9 sources (see all 11 ): (articles sorted by number of sources associating them with ZFP62) Utopia : connect your pdf to the dynamic world of online information
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Differentiation dependent expression in muscle cells of ZT3, a novel zinc finger factor differentially expressed in embryonic and adult tissues. (PubMed id 8808410) 1 , 3 Polimeni M....Bouche M. (1996) Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724) 1 Udeshi N.D....Carr S.A. (2012) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 Rose J.E....Uhl G.R. (2010) Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross- validation of MS/MS and MS/MS/MS spectra. (PubMed id 17924679) 1 Yu L.-R.... Veenstra T.D. (2007) The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005) 2 Bechtel S.... Schupp I. (2007) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022) 2 Schmutz J.... Rubin E.M. (2004) Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197) 1 Brandenberger R.... Stanton L.W. (2004)
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External Searches for ZFP62 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ZFP62 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing ZFP62 gene
(According to HUGE )
About This Section --
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Specialized Databases showing ZFP62 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for ZFP62 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for ZFP62 gene: Search GeneIP for patents involving ZFP62 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ZFP62 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for ZFP62 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for ZFP62 Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for ZFP62 OriGene 3'-UTR Clone for ZFP62 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ZFP62 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ZFP62 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for ZFP62 OriGene Custom Protein Services for ZFP62 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZFP62 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ZFP62 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ZFP62 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat ZFP62 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ZFP62 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ZFP62
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFP62
ThermoFisher Antibodies for ZFP62
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ZFP62
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