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Aliases for ZFP62 Gene

Aliases for ZFP62 Gene

  • ZFP62 Zinc Finger Protein 2 3
  • Zfp-62 3 4
  • Zinc Finger Protein 62 Homolog (Mouse) 2
  • Zinc Finger Protein 62 Homolog 3
  • Zinc Finger Protein 62 2
  • ZNF755 3
  • ZET 3

External Ids for ZFP62 Gene

Previous GeneCards Identifiers for ZFP62 Gene

  • GC05M180338
  • GC05M180385
  • GC05M9A0012
  • GC05M9B0012
  • GC05M180209
  • GC05M180274
  • GC05M174999

Summaries for ZFP62 Gene

GeneCards Summary for ZFP62 Gene

ZFP62 (ZFP62 Zinc Finger Protein) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF268.

UniProtKB/Swiss-Prot for ZFP62 Gene

  • May play a role in differentiating skeletal muscle.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFP62 Gene

Genomics for ZFP62 Gene

Regulatory Elements for ZFP62 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZFP62 Gene

Start:
180,845,435 bp from pter
End:
180,861,338 bp from pter
Size:
15,904 bases
Orientation:
Minus strand

Genomic View for ZFP62 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZFP62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP62 Gene

Proteins for ZFP62 Gene

  • Protein details for ZFP62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NB50-ZFP62_HUMAN
    Recommended name:
    Zinc finger protein 62 homolog
    Protein Accession:
    Q8NB50
    Secondary Accessions:
    • B4DIP6
    • B4E0N3
    • B5MDX6
    • B7ZVZ2
    • B9EIP6
    • E9PFT8
    • J3QTA9

    Protein attributes for ZFP62 Gene

    Size:
    900 amino acids
    Molecular mass:
    102511 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI40762.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC03691.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAG58558.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical GTG valine codon.; Evidence={ECO:0000305}; Sequence=CAI46133.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZFP62 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZFP62 Gene

Proteomics data for ZFP62 Gene at MOPED

Post-translational modifications for ZFP62 Gene

  • Ubiquitination at Lys195 and Lys198
  • Modification sites at PhosphoSitePlus

Other Protein References for ZFP62 Gene

No data available for DME Specific Peptides for ZFP62 Gene

Domains for ZFP62 Gene

Gene Families for ZFP62 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZFP62 Gene

Suggested Antigen Peptide Sequences for ZFP62 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NB50

UniProtKB/Swiss-Prot:

ZFP62_HUMAN :
  • Q8NB50
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 23 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZFP62: view

Function for ZFP62 Gene

Molecular function for ZFP62 Gene

UniProtKB/Swiss-Prot Function: May play a role in differentiating skeletal muscle.

Gene Ontology (GO) - Molecular Function for ZFP62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZFP62: view

Animal Model Products

CRISPR Products

miRNA for ZFP62 Gene

miRTarBase miRNAs that target ZFP62

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZFP62 Gene

Localization for ZFP62 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP62 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZFP62 Gene COMPARTMENTS Subcellular localization image for ZFP62 gene
Compartment Confidence
nucleus 3
cytosol 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for ZFP62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZFP62: view

Pathways for ZFP62 Gene

SuperPathways for ZFP62 Gene

No Data Available

Interacting Proteins for ZFP62 Gene

Gene Ontology (GO) - Biological Process for ZFP62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZFP62: view

No data available for Pathways by source for ZFP62 Gene

Transcripts for ZFP62 Gene

mRNA/cDNA for ZFP62 Gene

(9) Additional mRNA sequences :
(5) REFSEQ mRNAs :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZFP62 Gene

ZFP62 zinc finger protein:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZFP62

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP62 Gene

No ASD Table

Relevant External Links for ZFP62 Gene

GeneLoc Exon Structure for
ZFP62
ECgene alternative splicing isoforms for
ZFP62

Expression for ZFP62 Gene

mRNA expression in normal human tissues for ZFP62 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZFP62 Gene

SOURCE GeneReport for Unigene cluster for ZFP62 Gene Hs.509227

genes like me logo Genes that share expressions with ZFP62: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZFP62 Gene

Orthologs for ZFP62 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZFP62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZFP62 35
  • 99.63 (n)
  • 99.56 (a)
ZFP62 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZFP62 35
  • 91.3 (n)
  • 92.44 (a)
ZFP62 36
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZFP62 35
  • 91.48 (n)
  • 91.67 (a)
ZFP62 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp62 35
  • 87.47 (n)
  • 88.71 (a)
Zfp62 16
Zfp62 36
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 50 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 48 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 53 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia RGD1560191 35
  • 87.98 (n)
  • 88.95 (a)
Species with no ortholog for ZFP62:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZFP62 Gene

ENSEMBL:
Gene Tree for ZFP62 (if available)
TreeFam:
Gene Tree for ZFP62 (if available)

Paralogs for ZFP62 Gene

Selected SIMAP similar genes for ZFP62 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZFP62: view

Variants for ZFP62 Gene

Sequence variations from dbSNP and Humsavar for ZFP62 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs168726 - 180,849,402(+) GTGTC(C/T)TGCCA missense, reference
rs190347 -- 180,846,033(-) TGCAA(G/T)TGGGA intron-variant
rs249313 -- 180,847,565(+) ATCTG(A/G)CACAC intron-variant, downstream-variant-500B
rs249314 -- 180,847,553(+) TACCC(A/C)ACAAA intron-variant, downstream-variant-500B
rs249315 -- 180,847,402(-) TGATC(C/G)TCGTT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZFP62 Gene

Variant ID Type Subtype PubMed ID
dgv1882e1 CNV Complex 17122850
dgv6n29 CNV Loss 16826518
nsv428133 CNV Gain 18775914
nsv820020 CNV Loss 19587683
nsv830566 CNV Loss 17160897

Relevant External Links for ZFP62 Gene

HapMap Linkage Disequilibrium report
ZFP62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZFP62 Gene

Disorders for ZFP62 Gene

Relevant External Links for ZFP62

Genetic Association Database (GAD)
ZFP62
Human Genome Epidemiology (HuGE) Navigator
ZFP62
genes like me logo Genes that share disorders with ZFP62: view

No data available for UniProtKB/Swiss-Prot for ZFP62 Gene

Publications for ZFP62 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Differentiation dependent expression in muscle cells of ZT3, a novel zinc finger factor differentially expressed in embryonic and adult tissues. (PMID: 8808410) Polimeni M. … BouchAc M. (Mech. Dev. 1996) 2 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3

Products for ZFP62 Gene

Sources for ZFP62 Gene

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