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Aliases for ZFP41 Gene

Aliases for ZFP41 Gene

  • ZFP41 Zinc Finger Protein 2 3 5
  • Zfp-41 3 4
  • Zinc Finger Protein 41 Homolog (Mouse) 2
  • ZNF753 3

External Ids for ZFP41 Gene

Previous GeneCards Identifiers for ZFP41 Gene

  • GC08P144404
  • GC08P144330
  • GC08P144331
  • GC08P139582

Summaries for ZFP41 Gene

GeneCards Summary for ZFP41 Gene

ZFP41 (ZFP41 Zinc Finger Protein) is a Protein Coding gene. An important paralog of this gene is GLI4.

UniProtKB/Swiss-Prot for ZFP41 Gene

  • A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFP41 Gene

Genomics for ZFP41 Gene

Regulatory Elements for ZFP41 Gene

Promoters for ZFP41 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZFP41 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZFP41 Gene

Chromosome:
8
Start:
143,246,821 bp from pter
End:
143,262,705 bp from pter
Size:
15,885 bases
Orientation:
Plus strand

Genomic View for ZFP41 Gene

Genes around ZFP41 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZFP41 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZFP41 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP41 Gene

Proteins for ZFP41 Gene

  • Protein details for ZFP41 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8Y5-ZFP41_HUMAN
    Recommended name:
    Zinc finger protein 41 homolog
    Protein Accession:
    Q8N8Y5
    Secondary Accessions:
    • D3DWJ5

    Protein attributes for ZFP41 Gene

    Size:
    198 amino acids
    Molecular mass:
    22806 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZFP41 Gene

Proteomics data for ZFP41 Gene at MOPED

Post-translational modifications for ZFP41 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZFP41 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZFP41 Gene

Domains & Families for ZFP41 Gene

Gene Families for ZFP41 Gene

Protein Domains for ZFP41 Gene

Suggested Antigen Peptide Sequences for ZFP41 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N8Y5

UniProtKB/Swiss-Prot:

ZFP41_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 4 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZFP41: view

Function for ZFP41 Gene

Molecular function for ZFP41 Gene

UniProtKB/Swiss-Prot Function:
A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis.

Phenotypes for ZFP41 Gene

GenomeRNAi human phenotypes for ZFP41:
genes like me logo Genes that share phenotypes with ZFP41: view

Animal Model Products

miRNA for ZFP41 Gene

miRTarBase miRNAs that target ZFP41

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZFP41 Gene

Localization for ZFP41 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP41 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZFP41 Gene COMPARTMENTS Subcellular localization image for ZFP41 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZFP41 Gene

Pathways & Interactions for ZFP41 Gene

SuperPathways for ZFP41 Gene

No Data Available

Interacting Proteins for ZFP41 Gene

Gene Ontology (GO) - Biological Process for ZFP41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0007275 multicellular organism development IEA --
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with ZFP41: view

No data available for Pathways by source and SIGNOR curated interactions for ZFP41 Gene

Drugs & Compounds for ZFP41 Gene

No Compound Related Data Available

Transcripts for ZFP41 Gene

mRNA/cDNA for ZFP41 Gene

(2) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZFP41 Gene

ZFP41 zinc finger protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP41 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14
SP1:
SP2: - -
SP3: - - - - - -
SP4: - - -
SP5: - - - -
SP6: - -
SP7: - - - -
SP8: - -
SP9: -
SP10:

Relevant External Links for ZFP41 Gene

GeneLoc Exon Structure for
ZFP41
ECgene alternative splicing isoforms for
ZFP41

Expression for ZFP41 Gene

mRNA expression in normal human tissues for ZFP41 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZFP41 Gene Hs.668016

genes like me logo Genes that share expression patterns with ZFP41: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZFP41 Gene

Orthologs for ZFP41 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZFP41 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZFP41 35
  • 77.66 (n)
  • 74.61 (a)
dog
(Canis familiaris)
Mammalia ZFP41 35
  • 81.37 (n)
  • 80 (a)
-- 36
  • 82 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp41 35
  • 78.17 (n)
  • 81.22 (a)
Zfp41 16
Zfp41 36
  • 81 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia ZFP41 35
  • 99.33 (n)
  • 99.49 (a)
-- 36
  • 99 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii BX649341.4 36
  • 34 (a)
ManyToMany
si:dkey-247i3.7 36
  • 18 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea mnm-2 36
  • 15 (a)
OneToMany
Species with no ortholog for ZFP41:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZFP41 Gene

ENSEMBL:
Gene Tree for ZFP41 (if available)
TreeFam:
Gene Tree for ZFP41 (if available)

Paralogs for ZFP41 Gene

Paralogs for ZFP41 Gene

(489) SIMAP similar genes for ZFP41 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZFP41 Gene

genes like me logo Genes that share paralogs with ZFP41: view

Variants for ZFP41 Gene

Sequence variations from dbSNP and Humsavar for ZFP41 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs3511 -- 143,253,477(-) AGCTA(A/G)TTGTT intron-variant, utr-variant-3-prime
rs1056449 -- 143,262,286(+) CTGGA(C/T)GCCTG utr-variant-3-prime
rs2272631 -- 143,253,125(+) CCTGG(A/G)TTGTA intron-variant, utr-variant-3-prime
rs2272632 -- 143,253,158(+) AGGCA(C/T)AGTCA intron-variant, utr-variant-3-prime
rs3750211 -- 143,260,214(+) GAAAT(C/T)GTGCA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZFP41 Gene

Variant ID Type Subtype PubMed ID
dgv7920n71 CNV Loss 21882294
nsv891656 CNV Gain 21882294
nsv465992 CNV Loss 19166990
dgv7921n71 CNV Loss 21882294
nsv891660 CNV Loss 21882294
nsv891664 CNV Gain 21882294
dgv7922n71 CNV Loss 21882294
dgv7923n71 CNV Loss 21882294
nsv891669 CNV Loss 21882294
nsv891671 CNV Loss 21882294
esv2737981 CNV Deletion 23290073

Variation tolerance for ZFP41 Gene

Residual Variation Intolerance Score: 72.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.09; 22.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZFP41 Gene

HapMap Linkage Disequilibrium report
ZFP41

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZFP41 Gene

Disorders for ZFP41 Gene

Relevant External Links for ZFP41

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZFP41

No disorders were found for ZFP41 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZFP41 Gene

Publications for ZFP41 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Characterization of long cDNA clones from human adult spleen. (PMID: 11214971) Hattori A. … Ohara O. (DNA Res. 2000) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Expression of a mouse zinc finger protein gene in both spermatocytes and oocytes during meiosis. (PMID: 1397691) Noce T. … Higashinakagawa T. (Dev. Biol. 1992) 3

Products for ZFP41 Gene

Sources for ZFP41 Gene

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