Aliases for ZFP36L1 Gene
External Ids for ZFP36L1 Gene
Previous HGNC Symbols for ZFP36L1 Gene
Previous GeneCards Identifiers for ZFP36L1 Gene
This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
GeneCards Summary for ZFP36L1 Gene
ZFP36L1 (ZFP36 Ring Finger Protein Like 1) is a Protein Coding gene. Diseases associated with ZFP36L1 include Sotos Syndrome 1. Among its related pathways are Validated targets of C-MYC transcriptional repression and Gene Expression. GO annotations related to this gene include poly(A) RNA binding and mRNA binding. An important paralog of this gene is ZFP36L2.
UniProtKB/Swiss-Prot for ZFP36L1 Gene
Probable regulatory protein involved in regulating the response to growth factors.