Aliases for ZFP36 Gene
External Ids for ZFP36 Gene
GeneCards Summary for ZFP36 Gene
ZFP36 (ZFP36 Ring Finger Protein) is a Protein Coding gene. Among its related pathways are Spinal Cord Injury and ErbB1 downstream signaling. GO annotations related to this gene include protein kinase binding and single-stranded RNA binding. An important paralog of this gene is ZFP36L2.
UniProtKB/Swiss-Prot for ZFP36 Gene
mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).