ZFP30 Gene
protein-coding GIFtS: 43
GCID: GC19M038123
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ZFP30 zinc finger protein(Previous name: zinc finger protein 30 homolog (mouse) )
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Aliases
for ZFP30 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ZFP30 Zinc Finger Protein1 2 | | Zinc Finger Protein 30 Homolog (Mouse)1 | | ZNF7451 2 3 | | Zfp-303 | | KIAA09611 3 | | Zinc Finger Protein 30 Homolog2 | | Zinc Finger Protein 7452 3 | | Zfp-303 |
Export aliases for ZFP30 gene to outside databasesPrevious GC identifers: GC19M042799 GC19M042815 GC19U900417 GC19M034573 |
Summaries
for ZFP30 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZFP30_HUMAN, Q9Y2G7Function: May be involved in transcriptional regulation
|
Genomic Views
for ZFP30 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZFP30 gene promoter:
CUTL1 E4BP4 POU3F2 Evi-1 C/EBPalpha AREB6 POU2F1 POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZFP30
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZFP30 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.12 Ensembl cytogenetic band: 19q13.12 HGNC cytogenetic band: 19q13.13ZFP30 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M038123: view genomic region
(about GC identifiers)
Start:
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38,104,650 bp from pter |
End:
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38,183,238 bp from pter |
Size:
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78,589 bases |
Orientation:
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minus strand |
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Proteins
for ZFP30 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZFP30_HUMAN, Q9Y2G7 (See
protein sequence)Recommended Name: Zinc finger protein 30 homolog Size: 519 amino acids; 61558 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=BAA76805.2; Type=Erroneous initiation;
Secondary accessions: Q58EY8Explore the universe of human proteins at neXtProt for ZFP30: NX_Q9Y2G7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y2G7
ZFP30 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055713.1
ENSEMBL proteins: ENSP00000467387 ENSP00000343581 ENSP00000422930 ENSP00000466563 ENSP00000465496 ENSP00000466993 ENSP00000468295 ENSP00000375988
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZFP30 for ontologies About GeneDecksing
ZFP30 Antibody Products:
Assay Products for ZFP30: |
Protein
Domains /
Families
for ZFP30 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZFP30 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y2G7ProtoNet protein and cluster: Q9Y2G7 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZFP30_HUMAN, Q9Y2G7Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 13 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZFP30 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZFP30_HUMAN, Q9Y2G7Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZFP30 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZFP30
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ZFP30 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFP30 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFP30 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZFP30 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZFP30 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZFP30
1 Interacting protein for ZFP30 (Q9Y2G73) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZFP30 for ontologies About GeneDecksing
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Drugs & Compounds
for ZFP30 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZFP30
Search CenterWatch for drugs/clinical trials and news about ZFP30
|
Transcripts
for ZFP30 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZFP30 gene: NM_014898.2 Unigene Cluster for ZFP30: ZFP30 zinc finger protein Hs.716719 [show with all ESTs]Unigene Representative Sequence: AB02317812 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000589018 ENST00000351218(uc002ogv.1 uc002ogw.1 uc002ogx.1)
ENST00000514101(uc010xtt.1) ENST00000587809 ENST00000588979 ENST00000477900
ENST00000587199 ENST00000591444 ENST00000589676 ENST00000586732 ENST00000589789
ENST00000392144
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZFP30 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZFP30
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZFP30 (NM_014898) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZFP30 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFP30 |
Additional cDNA sequence: AB023178.1 AK297301.1 BC041087.1 BC050542.1 GU388430.1 10 DOTS entries: DT.97825241 DT.91706566 DT.97793576 DT.121418683 DT.91668084 DT.95161362 DT.102825722 DT.121418451 DT.100740187 DT.97833265
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for ZFP30 (see all 7) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b |
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| SP1: | | | | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP4: | | | - | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | |
| SP5: | | | | | - | | - | | - | | | | | | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for ZFP30
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Expression
for ZFP30 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZFP30 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCGGCTCTC
About this image
See ZFP30 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZFP30
SOURCE GeneReport for Unigene cluster: Hs.716719
SABiosciences Custom PCR Arrays for ZFP30
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZFP30
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZFP30 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZFP30 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZFP30 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFP30 |
Orthologs
for ZFP30 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZFP30 (if available)
TreeFam Gene Tree for ZFP30 (if available) |
Paralogs
for ZFP30 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZFP30 gene
- ZNF4202 ZNF5292 ZNF1402 ZNF780A2 ZNF3832 ZNF7902 ZNF5822 ZFP822
- ZNF302 ZNF5732 ZNF5402 ZNF5712 ZNF3312 ZFP142 ZNF4612 ZNF2832
- ZNF4042 ZNF8292 ZNF6072 ZNF5652 ZNF5662 ENSG000002675522
18/457 SIMAP similar genes for ZFP30 using alignment to 5 protein entries: ZFP30_HUMAN (see all proteins)
(see all similar genes):MGC12518 ZNF738 ZFP82 ZNF790 ZNF420 ZNF461
ZNF493 ZNF331 ZNF573 ZNF559 ZNF519 ZNF566
ZNF212 ZNF232 ZNF93 ZNF273 ZNF726 ZFP90
ZFP30 for paralogs About GeneDecksing
|
Genomic Variants
for ZFP30 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZFP30 (38104650 - 38183238 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZFP30: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZFP30 |
|
Disorders
/ Diseases
for ZFP30 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZFP30 for disorders About MalaCards
ZFP30 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZFP30 (2 documents)
Export disorders for ZFP30 gene to outside databases
|
Publications
for ZFP30 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZFP30 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZFP30) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1 Oguri M....Yamada Y. (2010)
- Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1 Yoshida T....Yamada Y. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Zfp30, a KRAB domain containing zinc finger protein gene, maps to mouse chromosome 7. (PubMed id 7849402)1 Denny P. and Ashworth A. (1994)
|
External Searches for ZFP30 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZFP30 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZFP30 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZFP30 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZFP30 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZFP30 gene:
Search GeneIP for patents involving ZFP30
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZFP30 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZFP30 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZFP30 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZFP30 | | | OriGene Protein Over-expression Lysate for ZFP30 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for ZFP30 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZFP30 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZFP30 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZFP30 | | OriGene Custom Protein Services for ZFP30 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZFP30 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZFP30 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZFP30 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZFP30 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZFP30 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZFP30 |
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 |  |  |  | |
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 | | | ZFP30 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFP30 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZFP30 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFP30 |
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