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Aliases for ZFP14 Gene

Aliases for ZFP14 Gene

  • ZFP14 Zinc Finger Protein 2 3 5
  • Zinc Finger Protein 531 3 4
  • ZNF531 3 4
  • Zinc Finger Protein 14 Homolog (Mouse) 2
  • KIAA1559 4
  • Zfp-14 4

External Ids for ZFP14 Gene

Previous GeneCards Identifiers for ZFP14 Gene

  • GC19M041522
  • GC19M036828
  • GC19M033295
  • GC19M036829
  • GC19M037068
  • GC19M036387
  • GC19M036697

Summaries for ZFP14 Gene

GeneCards Summary for ZFP14 Gene

ZFP14 (ZFP14 Zinc Finger Protein) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF345.

UniProtKB/Swiss-Prot for ZFP14 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFP14 Gene

Genomics for ZFP14 Gene

Regulatory Elements for ZFP14 Gene

Enhancers for ZFP14 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZFP14 on UCSC Golden Path with GeneCards custom track

Promoters for ZFP14 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZFP14 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZFP14 Gene

36,334,453 bp from pter
36,379,203 bp from pter
44,751 bases
Minus strand

Genomic View for ZFP14 Gene

Genes around ZFP14 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZFP14 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZFP14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP14 Gene

Proteins for ZFP14 Gene

  • Protein details for ZFP14 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 14 homolog
    Protein Accession:
    Secondary Accessions:
    • A7MD23

    Protein attributes for ZFP14 Gene

    533 amino acids
    Molecular mass:
    63463 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB13385.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZFP14 Gene

Proteomics data for ZFP14 Gene at MOPED

Post-translational modifications for ZFP14 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZFP14 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZFP14 Gene

Domains & Families for ZFP14 Gene

Gene Families for ZFP14 Gene

Protein Domains for ZFP14 Gene

Suggested Antigen Peptide Sequences for ZFP14 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZFP14: view

Function for ZFP14 Gene

Molecular function for ZFP14 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZFP14: view

Animal Model Products

miRNA for ZFP14 Gene

miRTarBase miRNAs that target ZFP14

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZFP14 Gene

Localization for ZFP14 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP14 Gene

Subcellular locations from

Jensen Localization Image for ZFP14 Gene COMPARTMENTS Subcellular localization image for ZFP14 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZFP14 Gene

Pathways & Interactions for ZFP14 Gene

SuperPathways for ZFP14 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZFP14: view

Pathways by source for ZFP14 Gene

2 Reactome pathways for ZFP14 Gene

Interacting Proteins for ZFP14 Gene

Gene Ontology (GO) - Biological Process for ZFP14 Gene


No data available for SIGNOR curated interactions for ZFP14 Gene

Drugs & Compounds for ZFP14 Gene

No Compound Related Data Available

Transcripts for ZFP14 Gene

mRNA/cDNA for ZFP14 Gene

Unigene Clusters for ZFP14 Gene

ZFP14 zinc finger protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP14 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5
SP1: -
SP2: -

Relevant External Links for ZFP14 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZFP14 Gene

mRNA expression in normal human tissues for ZFP14 Gene

SOURCE GeneReport for Unigene cluster for ZFP14 Gene Hs.35524

genes like me logo Genes that share expression patterns with ZFP14: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZFP14 Gene

Orthologs for ZFP14 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZFP14 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZFP14 35
  • 92.12 (n)
  • 94.52 (a)
ZNF404 36
  • 54 (a)
(Canis familiaris)
Mammalia LOC100683244 35
  • 88.45 (n)
  • 87.69 (a)
ZFP14 36
  • 96 (a)
(Mus musculus)
Mammalia Zfp14 35
  • 83.33 (n)
  • 87.75 (a)
Zfp14 16
Zfp14 36
  • 87 (a)
(Pan troglodytes)
Mammalia ZFP14 35
  • 99.62 (n)
  • 99.44 (a)
ZFP14 36
  • 99 (a)
Species with no ortholog for ZFP14:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZFP14 Gene

Gene Tree for ZFP14 (if available)
Gene Tree for ZFP14 (if available)

Paralogs for ZFP14 Gene

(478) SIMAP similar genes for ZFP14 Gene using alignment to 3 proteins: Pseudogenes for ZFP14 Gene

genes like me logo Genes that share paralogs with ZFP14: view

Variants for ZFP14 Gene

Sequence variations from dbSNP and Humsavar for ZFP14 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs12976232 -- 36,357,555(+) cagta(C/T)tattt intron-variant
rs7343105 -- 36,349,166(+) gcgga(A/G)gtttc intron-variant
rs8100507 -- 36,334,101(+) accca(A/C)ccaat downstream-variant-500B
rs12982193 -- 36,358,256(+) caggc(A/G)tgcgc intron-variant
rs12983243 -- 36,357,942(+) tttac(C/T)atgtt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZFP14 Gene

Variant ID Type Subtype PubMed ID
nsv2474 CNV Loss 18451855
nsv833816 CNV Gain 17160897
nsv174 CNV Loss 15895083
dgv638e199 CNV Deletion 23128226
nsv821399 CNV Deletion 20802225
nsv9716 CNV Gain+Loss 18304495
esv26179 CNV Gain 19812545
nsv436255 CNV Deletion 17901297
nsv498900 CNV Loss 21111241
esv2718503 CNV Deletion 23290073
esv1010898 CNV Gain 20482838
nsv514898 CNV Loss 21397061
esv2421498 CNV Deletion 20811451

Variation tolerance for ZFP14 Gene

Residual Variation Intolerance Score: 36% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.66; 56.94% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZFP14 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZFP14 Gene

Disorders for ZFP14 Gene

Relevant External Links for ZFP14

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZFP14 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZFP14 Gene

Publications for ZFP14 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 67
  2. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZFP14 Gene

Sources for ZFP14 Gene