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Aliases for ZFP14 Gene

Aliases for ZFP14 Gene

  • ZFP14 Zinc Finger Protein 2 3
  • Zinc Finger Protein 531 3 4
  • ZNF531 3 4
  • Zinc Finger Protein 14 Homolog (Mouse) 2
  • Zinc Finger Protein 14 Homolog 3
  • KIAA1559 4
  • ZFP148 6
  • ZNF148 6
  • Zfp-14 4

External Ids for ZFP14 Gene

Summaries for ZFP14 Gene

GeneCards Summary for ZFP14 Gene

ZFP14 (ZFP14 Zinc Finger Protein) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF529.

UniProtKB/Swiss-Prot for ZFP14 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFP14 Gene

Genomics for ZFP14 Gene

Genomic Location for ZFP14 Gene

Start:
36,334,453 bp from pter
End:
36,379,224 bp from pter
Size:
44,772 bases
Orientation:
Minus strand

Genomic View for ZFP14 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZFP14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP14 Gene

Regulatory Elements for ZFP14 Gene

Proteins for ZFP14 Gene

  • Protein details for ZFP14 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HCL3-ZFP14_HUMAN
    Recommended name:
    Zinc finger protein 14 homolog
    Protein Accession:
    Q9HCL3
    Secondary Accessions:
    • A7MD23

    Protein attributes for ZFP14 Gene

    Size:
    533 amino acids
    Molecular mass:
    63463 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB13385.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZFP14 Gene

Proteomics data for ZFP14 Gene at MOPED

Post-translational modifications for ZFP14 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZFP14 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZFP14 Gene

Domains for ZFP14 Gene

Gene Families for ZFP14 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZFP14_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q9HCL3
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9HCL3
Similarity:
  • Contains 13 C2H2-type zinc fingers.:
    • Q9HCL3
genes like me logo Genes that share domains with ZFP14: view

Function for ZFP14 Gene

Molecular function for ZFP14 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZFP14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZFP14: view

Phenotypes for ZFP14 Gene

GenomeRNAi human phenotypes for ZFP14:
genes like me logo Genes that share phenotypes with ZFP14: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZFP14 Gene

Localization for ZFP14 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP14 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZFP14 Gene COMPARTMENTS Subcellular localization image for ZFP14 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZFP14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZFP14: view

Pathways for ZFP14 Gene

SuperPathways for ZFP14 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZFP14: view

Pathways by source for ZFP14 Gene

2 Reactome pathways for ZFP14 Gene

Interacting Proteins for ZFP14 Gene

Gene Ontology (GO) - Biological Process for ZFP14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZFP14: view

Transcripts for ZFP14 Gene

mRNA/cDNA for ZFP14 Gene

Unigene Clusters for ZFP14 Gene

ZFP14 zinc finger protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP14 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5
SP1: -
SP2: -
SP3:

Relevant External Links for ZFP14 Gene

GeneLoc Exon Structure for
ZFP14
ECgene alternative splicing isoforms for
ZFP14

Expression for ZFP14 Gene

mRNA expression in normal human tissues for ZFP14 Gene

SOURCE GeneReport for Unigene cluster for ZFP14 Gene Hs.35524

genes like me logo Genes that share expressions with ZFP14: view

Orthologs for ZFP14 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZFP14 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZFP14 36
  • 99.62 (n)
  • 99.44 (a)
ZFP14 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZFP14 36
  • 92.12 (n)
  • 94.52 (a)
ZNF404 37
  • 54 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia LOC100683244 36
  • 88.45 (n)
  • 87.69 (a)
ZFP14 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp14 36
  • 83.33 (n)
  • 87.75 (a)
Zfp14 16
Zfp14 37
  • 87 (a)
OneToOne
Species with no ortholog for ZFP14:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZFP14 Gene

ENSEMBL:
Gene Tree for ZFP14 (if available)
TreeFam:
Gene Tree for ZFP14 (if available)

Paralogs for ZFP14 Gene

Selected SIMAP similar genes for ZFP14 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZFP14 Gene

genes like me logo Genes that share paralogs with ZFP14: view

Variants for ZFP14 Gene

Sequence variations from dbSNP and Humsavar for ZFP14 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs2857 -- 36,334,556(+) AGGAT(C/T)GGGCT utr-variant-3-prime
rs16424 -- 36,336,957(+) AATTA(-/TT)TTTCT utr-variant-3-prime
rs1129375 -- 36,337,489(-) accta(A/T)cacaa utr-variant-3-prime
rs1129376 -- 36,337,315(-) acaga(C/T)ccaga utr-variant-3-prime
rs2918366 -- 36,336,002(-) ACCCC(A/G)GCACT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZFP14 Gene

Variant ID Type Subtype PubMed ID
nsv2474 CNV Loss 18451855
nsv833816 CNV Gain 17160897
nsv174 CNV Loss 15895083
dgv638e199 CNV Deletion 23128226
nsv821399 CNV Deletion 20802225
nsv9716 CNV Gain+Loss 18304495
esv26179 CNV Gain 19812545
nsv436255 CNV Deletion 17901297
nsv498900 CNV Loss 21111241
esv2718503 CNV Deletion 23290073
esv1010898 CNV Gain 20482838
nsv514898 CNV Loss 21397061
esv2421498 CNV Deletion 20811451

Relevant External Links for ZFP14 Gene

HapMap Linkage Disequilibrium report
ZFP14
Human Gene Mutation Database (HGMD)
ZFP14

Disorders for ZFP14 Gene

Relevant External Links for ZFP14

Genetic Association Database (GAD)
ZFP14
genes like me logo Genes that share disorders with ZFP14: view

No data available for UniProtKB/Swiss-Prot for ZFP14 Gene

Publications for ZFP14 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  5. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3

Products for ZFP14 Gene

Sources for ZFP14 Gene

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