Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms of Use
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
GeneCards Plus
- Premium Tools
  
  Learn more

Set Analyses:

VarElect

Advanced Search

ZFHX2 Gene

protein-coding GIFtS: 41
GCID: GC14M023990

Zinc Finger Homeobox 2

(Previous name: zinc finger protein 409)
(Previous symbol: ZNF409)

Search for ZFHX2
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

TryGeneCards Plus

Aliases
Zinc Finger Homeobox 2¹ ²		ZFH-5²
ZNF409¹ ² ³		Zinc Finger Homeobox Protein 2²
Zinc Finger Protein 409¹ ²		KIAA1056³
Zinc Finger Homeodomain Protein 2² ³		KIAA1762³
ZFH-2² ³

External Ids:	HGNC: 20152¹	Entrez Gene: 85446²	Ensembl: ENSG00000136367⁷	UniProtKB: Q9C0A1³

Export aliases for ZFHX2 gene to outside databases

Previous GC identifers: GC14M017777 GC14M021981 GC14M021982 GC14M021983 GC14M023059

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for ZFHX2 Gene:

ZFHX2 (zinc finger homeobox 2) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZFHX4.

UniProtKB/Swiss-Prot: ZFHX2_HUMAN, Q9C0A1

Function: May be involved in transcriptional regulation

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus

RefSeq DNA sequence:

NC_000014.9 NT_026437.13 NC_018925.2

Regulatory elements:

Regulatory transcription factor binding sites in the ZFHX2 gene promoter:
AP-2gamma Meis-1b GATA-2 GATA-1 YY1 HOXA5 AP-2beta AP-2alpha Meis-1 AP-2alphaA
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search Chromatin IP Primers for ZFHX2

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZFHX2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2 Ensembl cytogenetic band: 14q11.2 HGNC cytogenetic band: 14q11.2

ZFHX2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZFHX2 gene location

GeneLoc information about chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14M023990: view genomic region (about GC identifiers)

Start:	23,990,064 bp from pter	End:	24,025,401 bp from pter
Size:	35,338 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ZFHX2_HUMAN, Q9C0A1 (See protein sequence)

Recommended Name: Zinc finger homeobox protein 2

Size: 2572 amino acids; 274176 Da

Sequence caution: Sequence=BAA83008.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Secondary accessions: Q9UPU6

Alternative splicing: 2 isoforms: Q9C0A1-1 Q9C0A1-2

Explore the universe of human proteins at neXtProt for ZFHX2: NX_Q9C0A1

Explore proteomics data for ZFHX2 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See ZFHX2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_207646.2

ENSEMBL proteins:

ENSP00000413418 ENSP00000409464 ENSP00000451342

ZFHX2 Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom MassSpec OriGene Custom Protein Services for ZFHX2
	GenScript Custom Purified and Recombinant Proteins Services for ZFHX2
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for ZFHX2

ZFHX2 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for ZFHX2
	Novus Biologicals ZFHX2 Antibodies
	Abcam antibodies for ZFHX2
	Cloud-Clone Corp. Antibodies for ZFHX2
	Search ThermoFisher Antibodies for ZFHX2
	LSBio Antibodies in human, mouse, rat for ZFHX2

ZFHX2 Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for ZFHX2
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ZFHX2
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for ZFHX2 Cloud-Clone Corp. CLIAs for ZFHX2

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus

HGNC Gene Families:

ZFHX: Homeoboxes / ZF class

ZNF: Zinc fingers, C2H2-type

Selected InterPro protein domains (see all 8):

IPR027028 ZFHX2

IPR003604 Znf_U1

IPR015880 Znf_C2H2-like

IPR013087 Znf_C2H2/integrase_DNA-bd

IPR017970 Homeobox_CS

Graphical View of Domain Structure for InterPro Entry Q9C0A1

ProtoNet protein and cluster: Q9C0A1

UniProtKB/Swiss-Prot: ZFHX2_HUMAN, Q9C0A1

Similarity: Contains 13 C2H2-type zinc fingers

Similarity: Contains 3 homeobox DNA-binding domains

ZFHX2 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:

UniProtKB/Swiss-Prot Summary: ZFHX2_HUMAN, Q9C0A1

Function: May be involved in transcriptional regulation

Gene Ontology (GO): Selected molecular function terms (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003676	nucleic acid binding	--	--
GO:0003677	DNA binding	--	--
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0003779	actin binding	--	--
GO:0008270	zinc ion binding	IEA	--

ZFHX2 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for ZFHX2:

Increased gamma-H2AX phosphory

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Zfhx2):

no phenotypic analysis

ZFHX2 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZFHX2

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZFHX2

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZFHX2

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZFHX2

miRNA Products:		miRTarBase miRNAs that target ZFHX2: hsa-mir-375 (MIRT019857)

		Block miRNA regulation of human, mouse, rat ZFHX2 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate ZFHX2 (see all 39):
		hsa-miR-4328 hsa-miR-1224-3p hsa-miR-765 hsa-miR-1260b hsa-miR-486-3p hsa-miR-650 hsa-miR-3167 hsa-miR-654-5p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for ZFHX2
		Predesigned siRNA for gene silencing in human, mouse, rat ZFHX2

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for ZFHX2

Clone Products:		OriGene clones in human, mouse for ZFHX2 (see all 3) OriGene ORF clones in mouse, rat for ZFHX2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: ZFHX2 (NM_033400)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZFHX2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFHX2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ZFHX2
		Browse ESI BIO Cell Lines and PureStem Progenitors for ZFHX2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFHX2

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from UniProtKB/Swiss-Prot

ZFHX2_HUMAN, Q9C0A1: Nucleus (Probable)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
nucleus	4
cytosol	1

About this image

Gene Ontology (GO): 1 cellular component term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

ZFHX2 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for ZFHX2
Interactions:

Search GeneGlobe Interaction Network for ZFHX2

Gene Ontology (GO): 4 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-templated	IEA	--
GO:0006355	regulation of transcription, DNA-templated	--	--
GO:0007010	cytoskeleton organization	--	--
GO:0030534	adult behavior	IEA	--

ZFHX2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for ZFHX2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for ZFHX2 gene:

NM_033400.2

Unigene Cluster for ZFHX2:

Zinc finger homeobox 2

Hs.508937 [show with all ESTs]

Unigene Representative Sequence: NM_033400

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000419474(uc010akq.3 uc001wke.3) ENST00000606808 ENST00000412565

ENST00000555334

miRNA Products:		Block miRNA regulation of human, mouse, rat ZFHX2 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate ZFHX2 (see all 39):
		hsa-miR-4328 hsa-miR-1224-3p hsa-miR-765 hsa-miR-1260b hsa-miR-486-3p hsa-miR-650 hsa-miR-3167 hsa-miR-654-5p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for ZFHX2
		Predesigned siRNA for gene silencing in human, mouse, rat ZFHX2

Clone Products:		OriGene clones in human, mouse for ZFHX2 (see all 3) OriGene ORF clones in mouse, rat for ZFHX2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: ZFHX2 (NM_033400)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZFHX2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFHX2

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for ZFHX2
		Pre-validated RT² qPCR Primer Assay in human, mouse / rat ZFHX2
		QuantiTect SYBR Green Assays in human, mouse, rat ZFHX2
		QuantiFast Probe-based Assays in human, mouse, rat ZFHX2

Additional mRNA sequence:

AB028979.1 AB051549.1 BC144336.1 BC150606.1

6 DOTS entries:

DT.105925 DT.40310148 DT.75121693 DT.92037350 DT.91868937 DT.92424855

Selected AceView cDNA sequences (see all 33):

BM928251 BM142009 AB051549 CK819828 BM141735 BE673662 BM930209 BX283301

AA210939 BU688647 BE393586 AV704837 CK819827 BQ889378 AA535789 CF130285

AA976107 BU953894 AI582864 AI093184 BM683686 AW470308 AI216808 AA781938

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

ZFHX2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: ATGTTCCACT

About this image

ZFHX2 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

ZFHX2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.508937

Custom PCR Arrays for ZFHX2

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for ZFHX2
		Pre-validated RT² qPCR Primer Assay in human, mouse / rat ZFHX2
		QuantiTect SYBR Green Assays in human, mouse, rat ZFHX2
		QuantiFast Probe-based Assays in human, mouse, rat ZFHX2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFHX2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of animals.

Orthologs for ZFHX2 gene from Selected species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Zfhx2^{1 , 5}	zinc finger homeobox 2^{1, 5}	85.52(n)¹ 84.51(a)¹		14 (28.05 cM)⁵ 239102¹ NM_001039198.1¹ NP_001034287.1¹ 55060262⁵
lizard (Anolis carolinensis)	Reptilia	ZFHX2⁶	zinc finger homeobox 2	55(a)	1 ↔ 1	GL343680.1(15685-29581)
tropical clawed frog (Xenopus tropicalis)	Amphibia	zfhx2¹	zinc finger homeobox 2	54.18(n) 50.5(a)		100489378 XM_002941515.2 XP_002941561.2
zebrafish (Danio rerio)	Actinopterygii	zfhx2⁶	zinc finger homeobox 2	17(a)	1 ↔ 1	24(14482670-14496307) ENSDARG00000088880
fruit fly (Drosophila melanogaster)	Insecta	zfh2⁶	Zn finger homeodomain 2	15(a)	1 → many	4(522436-560418)
worm (Caenorhabditis elegans)	Secernentea	zfh-2⁶	Protein ZFH-2 (zfh-2) mRNA, complete cds	24(a)	1 → many	I(803368-835277) WBGene00022518

ENSEMBL Gene Tree for ZFHX2 (if available)
TreeFam Gene Tree for ZFHX2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

TryGeneCards Plus

Paralogs for ZFHX2 gene

ZFHX4² ZFHX3²

2 SIMAP similar genes for ZFHX2 using alignment to 6 protein entries: ZFHX2_HUMAN (see all proteins):

POU6F1 NKX2-5

ZFHX2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Structural Variations
Database of Genomic Variants (DGV) 1 variation for ZFHX2: About this table

Variant ID	Type	Subtype	PubMed ID
nsv524778	CNV	Loss	19592680

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing ZFHX2

DNA2.0 Custom Variant and Variant Library Synthesis for ZFHX2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus

ZFHX2 for disorders About GeneDecksing

Genetic Association Database (GAD): ZFHX2

Export disorders for ZFHX2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for ZFHX2 gene integrated from 10 sources:
(articles sorted by number of sources associating them with ZFHX2)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)^{1, 2, 3} Nagase T.... Ohara O. (DNA Res. 2000)
Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)^{1, 3} Kikuno R.... Ohara O. (DNA Res. 1999)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (amp 2008)
Sumoylation of heterogeneous nuclear ribonucleoproteins, zinc finger proteins, and nuclear pore complex proteins: a proteomic analysis. (PubMed id 15161980)¹ Li T.... Chock P.B. (Proc. Natl. Acad. Sci. U.S.A. 2004)
The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)² Heilig R.... Weissenbach J. (Nature 2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)¹ Dias Neto E....Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus

Entrez Gene: 85446	HGNC: 20152	AceView: ZFHX2	Ensembl:ENSG00000136367	euGenes: HUgn85446
ECgene: ZFHX2	H-InvDB: ZFHX2

(According to HUGE)
About This Section

TryGeneCards Plus

HUGE: KIAA1056 KIAA1762

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus

Name	Description
PharmGKB entry for ZFHX2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ZFHX2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

TryGeneCards Plus

Patent Information for ZFHX2 gene:
Search GeneIP for patents involving ZFHX2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus


	EMD Millipore genomic analysis products

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Enzyme Activity Assays/Reagents
	Browse ELISpot/FluoroSpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Luminex Assays
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Recombinant/Natural Proteins		Browse Stem Cell Products
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for ZFHX2
	Browse OriGene qPCR primer pairs and template standards		Browse OriGene Protein Over-expression Lysates
	OriGene Custom Mass Spec		OriGene clones in human, mouse for ZFHX2
	OriGene qSTAR qPCR primer pairs in human, mouse for ZFHX2		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for ZFHX2		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for ZFHX2		OriGene Custom Protein Services for ZFHX2

	Block miRNA regulation of human, mouse, rat ZFHX2 using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing ZFHX2
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZFHX2		Predesigned siRNA for gene silencing in human, mouse, rat ZFHX2
	QuantiFast Probe-based Assays in human, mouse, rat ZFHX2		QuantiTect SYBR Green Assays in human, mouse, rat ZFHX2
	Custom PCR Arrays for ZFHX2		Search Chromatin IP Primers for ZFHX2
	Pre-validated RT² qPCR Primer Assay in human, mouse / rat ZFHX2		Search GeneGlobe Interaction Network for ZFHX2
	Regulatory tfbs in ZFHX2 promoter

	GenScript Custom Purified and Recombinant Proteins Services for ZFHX2		GenScript cDNA clones with any tag delivered in your preferred vector for ZFHX2
	GenScript Custom Assay Services for ZFHX2		GenScript Custom overexpressing Cell Line Services for ZFHX2
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

Search for Antibodies & Assays

Search Tocris compounds for ZFHX2

	Browse Sino Biological Proteins
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	ZFHX2 antibodies

	Antibodies for ZFHX2
	See all of Abcam's Antibodies, Kits and Proteins for ZFHX2
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Proteins for ZFHX2
	Antibodies for ZFHX2
	ELISAs for ZFHX2
	CLIAs for ZFHX2

Browse ESI BIO Cell Lines and PureStem Progenitors for ZFHX2

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFHX2

	Browse SwitchGear 3'UTR luciferase reporter plasmids for ZFHX2
	Browse SwitchGear Promoter luciferase reporter plasmids for ZFHX2

Search ThermoFisher Antibodies for ZFHX2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFHX2

	inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZFHX2
	inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZFHX2

LSBio Antibodies in human, mouse, rat for ZFHX2

Customized transgenic rodents for:

	Humanization
	Biomarker expression
	Off-target effect monitoring
	Translational medicine
	Tissue-specific gene expresssion
	Time-controlled gene expresssion

Browse compounds at ApexBio

GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

View Random Gene

Category			(GIFtS: )
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes ZFHX2 gene at Home site.

Version: 3.12.136 22 July 2014
hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4

GeneCards Plus

Advanced Search

Export list of displayed genes

ZFHX2 Gene

Zinc Finger Homeobox 2

Aliases
for ZFHX2 gene

Summaries
for ZFHX2 gene

Genomic Views
for ZFHX2 gene

Proteins
for ZFHX2 gene

ZFHX2 Human Recombinant Protein Products:

ZFHX2 Antibody Products:

ZFHX2 Assay Products:

Domains /
Families
for ZFHX2 gene

Function
for ZFHX2 gene

Localization
for ZFHX2 gene

Pathways & Interactions
for ZFHX2 gene

Drugs & Compounds
for ZFHX2 gene

Transcripts
for ZFHX2 gene

Expression
for ZFHX2 gene

Orthologs
for ZFHX2 gene

Paralogs
for ZFHX2 gene

Genomic Variants
for ZFHX2 gene

Disorders / Diseases
for ZFHX2 gene

Publications
for ZFHX2 gene

External Searches for ZFHX2 gene

Genome Databases showing ZFHX2 gene

Other Databases showing ZFHX2 gene

Specialized Databases showing ZFHX2 gene

Intellectual Property
for ZFHX2 gene

Products
for ZFHX2 gene

View Random Gene

GeneCards Plus

Advanced Search

Export list of displayed genes

ZFHX2 Gene

Zinc Finger Homeobox 2

Aliasesfor ZFHX2 gene

Summariesfor ZFHX2 gene

Genomic Viewsfor ZFHX2 gene

Proteinsfor ZFHX2 gene

ZFHX2 Human Recombinant Protein Products:

ZFHX2 Antibody Products:

ZFHX2 Assay Products:

Domains /Familiesfor ZFHX2 gene

Functionfor ZFHX2 gene

Localizationfor ZFHX2 gene

Pathways & Interactionsfor ZFHX2 gene

Drugs & Compoundsfor ZFHX2 gene

Transcriptsfor ZFHX2 gene

Expression for ZFHX2 gene

Orthologsfor ZFHX2 gene

Paralogsfor ZFHX2 gene

Genomic Variantsfor ZFHX2 gene

Disorders / Diseasesfor ZFHX2 gene

Publicationsfor ZFHX2 gene

External Searches for ZFHX2 gene

Genome Databases showing ZFHX2 gene

Other Databases showing ZFHX2 gene

Specialized Databases showing ZFHX2 gene

Intellectual Propertyfor ZFHX2 gene

Productsfor ZFHX2 gene

View Random Gene

Aliases
for ZFHX2 gene

Summaries
for ZFHX2 gene

Genomic Views
for ZFHX2 gene

Proteins
for ZFHX2 gene

Domains /
Families
for ZFHX2 gene

Function
for ZFHX2 gene

Localization
for ZFHX2 gene

Pathways & Interactions
for ZFHX2 gene

Drugs & Compounds
for ZFHX2 gene

Transcripts
for ZFHX2 gene

Expression
for ZFHX2 gene

Orthologs
for ZFHX2 gene

Paralogs
for ZFHX2 gene

Genomic Variants
for ZFHX2 gene

Disorders / Diseases
for ZFHX2 gene

Publications
for ZFHX2 gene

Intellectual Property
for ZFHX2 gene

Products
for ZFHX2 gene