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Aliases for ZFC3H1 Gene

Aliases for ZFC3H1 Gene

  • Zinc Finger, C3H1-Type Containing 2 3
  • Coiled-Coil Domain-Containing Protein 131 3 4
  • Proline/Serine-Rich Coiled-Coil Protein 2 3 4
  • Proline/Serine-Rich Coiled-Coil 2 2 3
  • Coiled-Coil Domain Containing 131 2 3
  • CCDC131 3 4
  • PSRC2 3 4
  • Zinc Finger C3H1 Domain-Containing Protein 3
  • KIAA0546 4

External Ids for ZFC3H1 Gene

Previous Symbols for ZFC3H1 Gene

  • PSRC2
  • CCDC131

Summaries for ZFC3H1 Gene

GeneCards Summary for ZFC3H1 Gene

ZFC3H1 (Zinc Finger, C3H1-Type Containing) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFC3H1 Gene

Genomics for ZFC3H1 Gene

Genomic Location for ZFC3H1 Gene

Start:
71,609,472 bp from pter
End:
71,667,725 bp from pter
Size:
58,254 bases
Orientation:
Minus strand

Genomic View for ZFC3H1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZFC3H1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFC3H1 Gene

Regulatory Elements for ZFC3H1 Gene

Proteins for ZFC3H1 Gene

  • Protein details for ZFC3H1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O60293-ZC3H1_HUMAN
    Recommended name:
    Zinc finger C3H1 domain-containing protein
    Protein Accession:
    O60293
    Secondary Accessions:
    • Q6GMU1
    • Q6P2S9
    • Q6ZV36
    • Q96BE7

    Protein attributes for ZFC3H1 Gene

    Size:
    1989 amino acids
    Molecular mass:
    226356 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA25472.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC86028.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZFC3H1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZFC3H1 Gene

Proteomics data for ZFC3H1 Gene at MOPED

Post-translational modifications for ZFC3H1 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys880

Other Protein References for ZFC3H1 Gene

No data available for DME Specific Peptides for ZFC3H1 Gene

Domains for ZFC3H1 Gene

Gene Families for ZFC3H1 Gene

HGNC:
  • ZFC3H1 :Zinc finger, C3H1-type containing

Protein Domains for ZFC3H1 Gene

UniProtKB/Swiss-Prot:

ZC3H1_HUMAN
Similarity:
  • Contains 1 C3H1-type zinc finger.:
    • O60293
  • Contains 7 TPR repeats.:
    • O60293
genes like me logo Genes that share domains with ZFC3H1: view

Function for ZFC3H1 Gene

Gene Ontology (GO) - Molecular Function for ZFC3H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20195357
GO:0044822 poly(A) RNA binding IDA 22658674
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZFC3H1: view

Phenotypes for ZFC3H1 Gene

genes like me logo Genes that share phenotypes with ZFC3H1: view

miRNA for ZFC3H1 Gene

miRTarBase miRNAs that target ZFC3H1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZFC3H1 Gene

Localization for ZFC3H1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZFC3H1 Gene COMPARTMENTS Subcellular localization image for ZFC3H1 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZFC3H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 22664934
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ZFC3H1: view

Pathways for ZFC3H1 Gene

SuperPathways for ZFC3H1 Gene

No Data Available

Interacting Proteins for ZFC3H1 Gene

Gene Ontology (GO) - Biological Process for ZFC3H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with ZFC3H1: view

No data available for Pathways by source for ZFC3H1 Gene

Transcripts for ZFC3H1 Gene

Unigene Clusters for ZFC3H1 Gene

Zinc finger, C3H1-type containing:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZFC3H1 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17a · 17b · 17c ^
SP1: -
SP2: -
SP3:
SP4:
SP5: - - - -
SP6: - - -
SP7:
SP8:
SP9: - -
SP10:
SP11:
SP12:

ExUns: 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30a · 30b ^ 31a · 31b ^ 32 ^ 33a · 33b · 33c ^ 34a · 34b · 34c ^ 35a · 35b ^ 36 ^
SP1: - - - - -
SP2:
SP3:
SP4: - -
SP5:
SP6:
SP7: -
SP8:
SP9:
SP10:
SP11:
SP12:

ExUns: 37a · 37b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:

Relevant External Links for ZFC3H1 Gene

GeneLoc Exon Structure for
ZFC3H1
ECgene alternative splicing isoforms for
ZFC3H1

Expression for ZFC3H1 Gene

mRNA expression in normal human tissues for ZFC3H1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZFC3H1 Gene

SOURCE GeneReport for Unigene cluster for ZFC3H1 Gene Hs.527874

genes like me logo Genes that share expressions with ZFC3H1: view

Orthologs for ZFC3H1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZFC3H1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZFC3H1 36
  • 99.77 (n)
  • 99.85 (a)
ZFC3H1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZFC3H1 36
  • 93.65 (n)
  • 94.57 (a)
ZFC3H1 37
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZFC3H1 36
  • 93.04 (n)
  • 94.95 (a)
ZFC3H1 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfc3h1 36
  • 88.78 (n)
  • 91.58 (a)
Zfc3h1 16
Zfc3h1 37
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZFC3H1 37
  • 83 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZFC3H1 37
  • 79 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfc3h1 36
  • 88.97 (n)
  • 91.74 (a)
chicken
(Gallus gallus)
Aves ZFC3H1 36
  • 74.8 (n)
  • 73.97 (a)
ZFC3H1 37
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZFC3H1 37
  • 69 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.15668 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.235 36
zfc3h1 36
  • 64.83 (n)
  • 60.06 (a)
zebrafish
(Danio rerio)
Actinopterygii ZFC3H1 37
  • 28 (a)
OneToOne
Species with no ortholog for ZFC3H1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZFC3H1 Gene

ENSEMBL:
Gene Tree for ZFC3H1 (if available)
TreeFam:
Gene Tree for ZFC3H1 (if available)

Paralogs for ZFC3H1 Gene

No data available for Paralogs for ZFC3H1 Gene

Variants for ZFC3H1 Gene

Sequence variations from dbSNP and Humsavar for ZFC3H1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs724211 -- 71,641,830(+) GAGTA(A/G)TGTTC intron-variant
rs1011331 -- 71,633,092(-) AAGCC(A/G)CGGTG intron-variant
rs1011332 - 71,632,316(-) AACCC(A/G)AATTT missense, reference
rs1148987 -- 71,623,857(-) TATCC(A/G)CAGGT intron-variant
rs1148988 -- 71,624,882(-) TGAAG(C/T)GGTCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZFC3H1 Gene

Variant ID Type Subtype PubMed ID
nsv832451 CNV Loss 17160897

Relevant External Links for ZFC3H1 Gene

HapMap Linkage Disequilibrium report
ZFC3H1

Disorders for ZFC3H1 Gene

Relevant External Links for ZFC3H1

Genetic Association Database (GAD)
ZFC3H1
genes like me logo Genes that share disorders with ZFC3H1: view

No data available for UniProtKB/Swiss-Prot for ZFC3H1 Gene

Publications for ZFC3H1 Gene

  1. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9628581) Nagase T. … Ohara O. (DNA Res. 1998) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PMID: 20195357) Miyamoto-Sato E. … Yanagawa H. (PLoS ONE 2010) 3

Products for ZFC3H1 Gene

  • antibodies-online proteins for ZFC3H1
  • antibodies-online antibodies for ZFC3H1
  • antibodies-online kits for ZFC3H1

Sources for ZFC3H1 Gene

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