Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZFC3H1 Gene

protein-coding   GIFtS: 48
GCID: GC12M072003

Zinc Finger, C3H1-Type Containing

(Previous names: proline/serine-rich coiled-coil 2, coiled-coil domain containing...)
(Previous symbols: PSRC2, CCDC131)
  Search for ZFC3H1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger, C3H1-Type Containing1 2     Coiled-Coil Domain-Containing Protein 1312 3
CCDC1311 2 3     Proline/Serine-Rich Coiled-Coil Protein 22 3
PSRC21 2 3     Zinc Finger C3H1 Domain-Containing Protein2
Coiled-Coil Domain Containing 1311 2     KIAA05463
Proline/Serine-Rich Coiled-Coil 21 2     

External Ids:    HGNC: 283281   Entrez Gene: 1964412   Ensembl: ENSG000001338587   UniProtKB: O602933   

Export aliases for ZFC3H1 gene to outside databases

Previous GC identifers: GC12M070292 GC12M069052


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZFC3H1 Gene: 
ZFC3H1 (zinc finger, C3H1-type containing) is a protein-coding gene. GO annotations related to this gene include protein binding and metal ion binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZFC3H1 gene promoter:
         Nkx3-1   AML1a   Nkx3-1 v1   Nkx3-1 v2   POU2F1   POU2F1a   FOXO1a   Pax-4a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZFC3H1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZFC3H1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZFC3H1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q21.1   Ensembl cytogenetic band:  12q21.1   HGNC cytogenetic band: 12q21.1

ZFC3H1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZFC3H1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M072003:  view genomic region     (about GC identifiers)

Start:
72,003,252 bp from pter      End:
72,061,505 bp from pter
Size:
58,254 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZC3H1_HUMAN, O60293 (See protein sequence)
Recommended Name: Zinc finger C3H1 domain-containing protein  
Size: 1989 amino acids; 226356 Da
Sequence caution: Sequence=BAA25472.2; Type=Erroneous initiation; Sequence=BAC86028.1; Type=Erroneous initiation;
Secondary accessions: Q6GMU1 Q6P2S9 Q6ZV36 Q96BE7
Alternative splicing: 3 isoforms:  O60293-1   O60293-2   O60293-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZFC3H1: NX_O60293

Explore proteomics data for ZFC3H1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O60293

  • ZFC3H1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZFC3H1 Protein Expression
    REFSEQ proteins: NP_659419.3  
    ENSEMBL proteins: 
     ENSP00000368017   ENSP00000446995   ENSP00000450044   ENSP00000447976  

    Human Recombinant Protein Products for ZFC3H1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ZFC3H1
    GenScript Custom Purified and Recombinant Proteins Services for ZFC3H1
    Novus Biologicals ZFC3H1 Proteins
    Novus Biologicals ZFC3H1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZFC3H1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IEA--

    ZFC3H1 for ontologies           About GeneDecksing



    ZFC3H1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZFC3H1
    GenScript Custom Superior Antibodies Services for ZFC3H1
    Novus Biologicals ZFC3H1 Antibodies
    Abcam antibodies for ZFC3H1
    Cloud-Clone Corp. Antibodies for ZFC3H1 
    Search ThermoFisher Antibodies for ZFC3H1
    LSBio Antibodies in human, mouse, rat for ZFC3H1 

    Assay Products for ZFC3H1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZFC3H1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZFC3H1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZFC3H1 
    Cloud-Clone Corp. CLIAs for ZFC3H1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZFC3H1: Zinc finger, C3H1-type containing

    3 InterPro protein domains:
     IPR003107 HAT
     IPR019607 Putative_zinc-finger_domain
     IPR013026 TPR-contain_dom

    Graphical View of Domain Structure for InterPro Entry O60293

    ProtoNet protein and cluster: O60293

    1 Blocks protein domain: IPB003107 RNA-processing protein

    UniProtKB/Swiss-Prot: ZC3H1_HUMAN, O60293
    Similarity: Contains 1 C3H1-type zinc finger
    Similarity: Contains 6 HAT repeats
    Similarity: Contains 5 TPR repeats


    ZFC3H1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0046872metal ion binding IEA--
         
    ZFC3H1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ZFC3H1:
     Synthetic lethal with Ras  Upregulation of NF-kappaB path 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZFC3H1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZFC3H1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZFC3H1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZFC3H1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZFC3H1
    8/43 QIAGEN miScript miRNA Assays for microRNAs that regulate ZFC3H1 (see all 43):
    hsa-miR-579 hsa-miR-25 hsa-miR-301a hsa-miR-30d hsa-miR-632 hsa-miR-519a hsa-miR-30a hsa-miR-92b
    SwitchGear 3'UTR luciferase reporter plasmidZFC3H1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZFC3H1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZFC3H1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZFC3H1
    Sirion Biotech Customized adenovirus for overexpression of ZFC3H1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ZFC3H1 (see all 5)
    OriGene ORF clones in mouse, rat for ZFC3H1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZFC3H1 (NM_144982)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZFC3H1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFC3H1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZFC3H1
    Search LifeMap BioReagents cell lines for ZFC3H1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFC3H1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZFC3H1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for ZFC3H1 (O602931, 2, 3 ENSP000003680174) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158342, 3, ENSP000003116954MINT-68301 I2D: score=4 STRING: ENSP00000311695
    NINLQ9Y2I62, 3, ENSP000002788864MINT-66893 I2D: score=4 STRING: ENSP00000278886
    MYBP102421, 3EBI-746701,EBI-298355 I2D: score=1 
    SUMO1P631653, ENSP000003760764I2D: score=1 STRING: ENSP00000376076
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006396RNA processing IEA--

    ZFC3H1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZFC3H1 (ZC3H1)

    Search CenterWatch for drugs/clinical trials and news about ZFC3H1 / ZC3H1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZFC3H1 gene: 
    NM_144982.4  

    Unigene Cluster for ZFC3H1:

    Zinc finger, C3H1-type containing
    Hs.527874  [show with all ESTs]
    Unigene Representative Sequence: NM_144982
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000378743(uc001swo.2) ENST00000552994 ENST00000550963 ENST00000547398
    ENST00000551487 ENST00000546475 ENST00000546771 ENST00000546606 ENST00000550712
    ENST00000548100(uc001swp.3) ENST00000552037(uc010sts.2) ENST00000549407

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZFC3H1
    8/43 QIAGEN miScript miRNA Assays for microRNAs that regulate ZFC3H1 (see all 43):
    hsa-miR-579 hsa-miR-25 hsa-miR-301a hsa-miR-30d hsa-miR-632 hsa-miR-519a hsa-miR-30a hsa-miR-92b
    SwitchGear 3'UTR luciferase reporter plasmidZFC3H1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZFC3H1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZFC3H1
    Clone
    Products:
         
    OriGene clones in human, mouse for ZFC3H1 (see all 5)
    OriGene ORF clones in mouse, rat for ZFC3H1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZFC3H1 (NM_144982)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZFC3H1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFC3H1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ZFC3H1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZFC3H1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZFC3H1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZFC3H1

    Additional mRNA sequence: 

    AK125035.1 BC015679.2 BC064336.1 BC073843.1 BX647709.1 

    9 DOTS entries:

    DT.100729720  DT.91640914  DT.442262  DT.91833909  DT.100754893  DT.121138658  DT.100754888  DT.95159609 
    DT.40119817 

    24/145 AceView cDNA sequences (see all 145):

    NM_144982 AK125035 AI801082 CB321747 AW192423 BM828166 AA868849 AI082803 
    BM674787 AI275470 AL691758 AW168746 AI184530 BE646534 BX281504 AA904589 
    BC015679 AA476680 AI338673 AW302562 AI439363 AI933005 AW197148 BG676919 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for ZFC3H1 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17a · 17b · 17c ^
    SP1:                                                                                                                                -                           
    SP2:                                                                                                                                -                           
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:              -     -           -     -                                                                                                                     

    ExUns: 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30a · 30b ^ 31a · 31b ^ 32 ^ 33a · 33b · 33c ^ 34a · 34b · 34c ^ 35a · 35b ^ 36 ^
    SP1:                                                                                      -                 -                       -     -     -               
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                      -                 -                                                   
    SP5:                                                                                                                                                            

    ExUns: 37a · 37b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for ZFC3H1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZFC3H1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCACAAGTC
    ZFC3H1 Expression
    About this image


    See ZFC3H1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZFC3H1

    SOURCE GeneReport for Unigene cluster: Hs.527874
        SABiosciences Custom PCR Arrays for ZFC3H1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ZFC3H1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZFC3H1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZFC3H1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZFC3H1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFC3H1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ZFC3H1 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfc3h11 , 5 zinc finger, C3H1-type containing1, 5 89.01(n)1
    91.93(a)1
      10 (63.51 cM)5
    2163451  NM_001033261.21  NP_001028433.21 
     1153849595 
    chicken
    (Gallus gallus)
    Aves ZFC3H11 zinc finger, C3H1-type containing 75.27(n)
    74.64(a)
      417855  XM_416097.3  XP_416097.3 
    lizard
    (Anolis carolinensis)
    Reptilia ZFC3H16
    zinc finger, C3H1-type containing
    69(a)
    1 ↔ 1
    5(38387908-38427109)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.156682 Xenopus laevis transcribed sequence with weak similarity more 81.02(n)    CD254486.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ZFC3H16
    zinc finger, C3H1-type containing
    28(a)
    1 ↔ 1
    25(38491810-38495066)


    ENSEMBL Gene Tree for ZFC3H1 (if available)
    TreeFam Gene Tree for ZFC3H1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1147 SNPs in ZFC3H1 are shown (see all 1147)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1869561431,2
    --72002924(+) GGTTGA/CTGCTC 1 -- ds50010--------
    rs1929841201,2
    --72002930(+) TGCTCC/TGCCTC 1 -- ds50010--------
    rs171099521,2
    C,F,H--72003129(+) AACTAC/TGGTTG 1 -- ds500114Minor allele frequency- T:0.03NA NS EA CSA WA 1344
    rs1852753201,2
    --72003130(+) ACTACA/GGTTGG 1 -- ds50010--------
    rs1401564301,2
    C--72003225(+) ATCCA-/TCTTCTCA 1 -- ds50010--------
    rs1887987111,2
    --72003266(+) TTTTAA/GTGGGA 1 -- ds50010--------
    rs1461367251,2
    --72003321(+) TATCCA/GTATCT 1 -- ds50010--------
    rs118374861,2
    C,F,A,H--72003423(+) AATTTC/TAATAC 1 -- ut313Minor allele frequency- T:0.08NS NA WA 228
    rs1932163441,2
    --72003530(+) GCACAC/TAATAT 1 -- ut310--------
    rs1390091051,2
    --72003715(+) GACTGC/TTATAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ZFC3H1 (72003252 - 72061505 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ZFC3H1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv832451CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ZFC3H1
    DNA2.0 Custom Variant and Variant Library Synthesis for ZFC3H1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ZFC3H1 for disorders           About MalaCards

    ZFC3H1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZFC3H1

    Export disorders for ZFC3H1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZFC3H1 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with ZFC3H1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2, 3 Nagase T....Ohara O. (1998)
    2. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    3. A bead-based approach for large-scale identification o f in vitro kinase substrates. (PubMed id 22113938)1 Zhang M....Zou H. (2011)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    5. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    6. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    7. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    10. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 196441 HGNC: 28328 AceView: MGC23401 Ensembl:ENSG00000133858 euGenes: HUgn196441
    ECgene: ZFC3H1 H-InvDB: ZFC3H1

    (According to HUGE)
    About This Section
    HUGE: KIAA0546

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZFC3H1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZFC3H1 gene:
    Search GeneIP for patents involving ZFC3H1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZFC3H1  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ZFC3H1  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZFC3H1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ZFC3H1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZFC3H1   OriGene Custom Protein Services for ZFC3H1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZFC3H1
     QIAGEN SeqTarget long-range PCR primers for resequencing ZFC3H1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZFC3H1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZFC3H1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZFC3H1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZFC3H1
     GenScript Custom Purified and Recombinant Proteins Services for ZFC3H1 GenScript cDNA clones with any tag delivered in your preferred vector for ZFC3H1
     GenScript Custom Assay Services for ZFC3H1 GenScript Custom Superior Antibodies Services for ZFC3H1
     GenScript Custom overexpressing Cell Line Services for ZFC3H1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ZFC3H1 promoter
     Search Chromatin IP Primers for ZFC3H1
     RT2 qPCR Primer Assay in human, mouse, rat ZFC3H1
     Search GNC Networks for ZFC3H1
     SABiosciences Custom PCR Arrays for ZFC3H1
     Search Tocris compounds for ZFC3H1 (ZC3H1)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ZFC3H1 antibodies
     ZFC3H1 proteins
     ZFC3H1 lysates
     Antibodies for ZFC3H1
     See all of Abcam's Antibodies, Kits and Proteins for ZFC3H1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ZFC3H1
     Antibodies for ZFC3H1
     ELISAs for ZFC3H1
     CLIAs for ZFC3H1
     Search LifeMap BioReagents cell lines for ZFC3H1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZFC3H1
     SwitchGear 3'UTR luciferase reporter plasmids for ZFC3H1
     SwitchGear Promoter luciferase reporter plasmids for ZFC3H1
     Search ThermoFisher Antibodies for ZFC3H1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZFC3H1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ZFC3H1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZFC3H1
    Customized:
     lentivirus for stable overexpression
     lentivirus expression plasmids for stable overexpression
     adenovirus for overexpression of ZFC3H1
     LSBio Antibodies in human, mouse, rat for ZFC3H1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZFC3H1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4