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Aliases for ZFAS1 Gene

Subcategory (RNA class) for ZFAS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for ZFAS1 Gene

  • ZNFX1 Antisense RNA 1 2 3 5
  • ZNFX1 Antisense RNA 1 (Non-Protein Coding) 2 3
  • Chromosome 20 Open Reading Frame 199 2
  • ZNFX1 Antisense Gene Protein 1 3
  • Non-Protein Coding RNA 275 2
  • NCRNA00275 3
  • C20orf199 3
  • ZNFX1-AS1 3
  • HSUP1 3
  • HSUP2 3

External Ids for ZFAS1 Gene

Previous HGNC Symbols for ZFAS1 Gene

  • C20orf199
  • NCRNA00275
  • ZNFX1-AS1

Previous GeneCards Identifiers for ZFAS1 Gene

  • GC20P047905
  • GC20P047910
  • GC20P047917
  • GC20P049281
  • GC20P049288
  • GC20P049292
  • GC20P049296
  • GC20P049300
  • GC20P049306
  • GC20P049310

Summaries for ZFAS1 Gene

Entrez Gene Summary for ZFAS1 Gene

  • This gene represents a snoRNA host gene that produces a non-coding RNA. Increased expression or amplification of this locus is associated with cancer progression and metastasis. This transcript regulates expression of genes involved in differentiation. It may act a molecular sponge for microRNAs. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Dec 2017]

GeneCards Summary for ZFAS1 Gene

ZFAS1 (ZNFX1 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for ZFAS1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFAS1 Gene

Genomics for ZFAS1 Gene

GeneHancer (GH) Regulatory Elements for ZFAS1 Gene

Promoters and enhancers for ZFAS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20I049275 Promoter/Enhancer 2.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 570.7 +1.8 1777 9.2 CLOCK MLX ZFP64 FEZF1 DMAP1 YBX1 IRF4 YY1 SLC30A9 ZNF213 ZNFX1 SNORD12B ZFAS1 SNORD12 ENSG00000277967 GC20P049313 GC20P049317 GC20P049318 GC20P049319 GC20P049320
GH20I050186 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.2 +913.1 913100 10.3 CLOCK MLX ZFP64 YBX1 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 CEBPB CEBPB-AS1 GC20P050191 ADNP DDX27 DPM1 MOCS3 ENSG00000232043 SNORD12B LINC01273
GH20I049218 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 11.9 -58.4 -58439 2.5 HDGF PKNOX1 FOXA2 SMAD1 MLX ARID4B SIN3A DMAP1 ZNF2 IRF4 DDX27 ZFAS1 STAU1 CSE1L PIR41098
GH20I049981 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 10.2 +705.4 705353 3.3 HDGF PKNOX1 CLOCK SMAD1 MLX ZFP64 ARID4B SIN3A YBX1 DMAP1 SNAI1 DDX27 ADNP ENSG00000232043 SNORD12B SLC9A8 MOCS3 RNF114 PSMD10P1 DPM1
GH20I049045 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 10.2 -231.3 -231320 3 HDGF PKNOX1 SMAD1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 CSE1L CSE1L-AS1 DDX27 RNF114 SNORD12B ZNFX1 ZFAS1 ARFGEF2 SNORD12 GC20P049089
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZFAS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZFAS1 Gene

Genomic Locations for ZFAS1 Gene
chr20:49,278,178-49,295,738
(GRCh38/hg38)
Size:
17,561 bases
Orientation:
Plus strand
chr20:47,894,715-47,905,797
(GRCh37/hg19)

Genomic View for ZFAS1 Gene

Genes around ZFAS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZFAS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZFAS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFAS1 Gene

Proteins for ZFAS1 Gene

Post-translational modifications for ZFAS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZFAS1 Gene

Domains & Families for ZFAS1 Gene

Gene Families for ZFAS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZFAS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ZFAS1 Gene

Function for ZFAS1 Gene

Phenotypes From GWAS Catalog for ZFAS1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZFAS1 Gene

Localization for ZFAS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ZFAS1 Gene

Pathways & Interactions for ZFAS1 Gene

SuperPathways for ZFAS1 Gene

No Data Available

Interacting Proteins for ZFAS1 Gene

Gene Ontology (GO) - Biological Process for ZFAS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZFAS1 Gene

Drugs & Compounds for ZFAS1 Gene

No Compound Related Data Available

Transcripts for ZFAS1 Gene

Unigene Clusters for ZFAS1 Gene

ZNFX1 antisense RNA 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZFAS1 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8
SP1: - - -
SP2: - - -
SP3: - - - - - -
SP4: - - - -
SP5: - - -
SP6: - - - - - -
SP7: - - - - -
SP8: -
SP9:

Relevant External Links for ZFAS1 Gene

GeneLoc Exon Structure for
ZFAS1
ECgene alternative splicing isoforms for
ZFAS1

Expression for ZFAS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZFAS1 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZFAS1 Gene:

ZFAS1

SOURCE GeneReport for Unigene cluster for ZFAS1 Gene:

Hs.356766
genes like me logo Genes that share expression patterns with ZFAS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZFAS1 Gene

Orthologs for ZFAS1 Gene

Evolution for ZFAS1 Gene

ENSEMBL:
Gene Tree for ZFAS1 (if available)
TreeFam:
Gene Tree for ZFAS1 (if available)

No data available for Orthologs for ZFAS1 Gene

Paralogs for ZFAS1 Gene

No data available for Paralogs for ZFAS1 Gene

Variants for ZFAS1 Gene

Sequence variations from dbSNP and Humsavar for ZFAS1 Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1000009454 -- 49,281,636(+) A/G intron_variant
rs1000042643 -- 49,277,336(+) G/C upstream_transcript_variant
rs1000070514 -- 49,279,695(+) T/C intron_variant
rs1000091221 -- 49,288,178(+) G/C intron_variant
rs1000182081 -- 49,283,955(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZFAS1 Gene

Variant ID Type Subtype PubMed ID
dgv1248e212 CNV loss 25503493
nsv1064443 CNV gain 25217958
nsv1067146 CNV loss 25217958
nsv1072545 CNV deletion 25765185
nsv437839 CNV loss 16327808

Additional Variant Information for ZFAS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZFAS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZFAS1 Gene

Disorders for ZFAS1 Gene

Additional Disease Information for ZFAS1

No disorders were found for ZFAS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZFAS1 Gene

Publications for ZFAS1 Gene

  1. SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer. (PMID: 21460236) Askarian-Amiri ME … Mattick JS (RNA (New York, N.Y.) 2011) 2 3 58
  2. LncRNA ZFAS1 promotes cell migration and invasion of fibroblast-like synoviocytes by suppression of miR-27a in rheumatoid arthritis. (PMID: 28721682) Ye Y … Yang N (Human cell 2018) 3 58
  3. Long non-coding RNA ZFAS1 sponges miR-484 to promote cell proliferation and invasion in colorectal cancer. (PMID: 29179614) Xie S … Kang Y (Cell cycle (Georgetown, Tex.) 2018) 3 58
  4. Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression. (PMID: 27246976) Nie F … Sun M (Oncotarget 2017) 3 58
  5. Long non-coding ribonucleic acid zinc finger antisense 1 promotes the progression of colonic cancer by modulating ZEB1 expression. (PMID: 27862275) Fang C … Yan D (Journal of gastroenterology and hepatology 2017) 3 58

Products for ZFAS1 Gene

Sources for ZFAS1 Gene

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