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Aliases for ZFAND2A Gene

Aliases for ZFAND2A Gene

  • Zinc Finger, AN1-Type Domain 2A 2 3
  • Arsenite Inducible RNA Associated Protein 2 3
  • AIRAP 3 6
  • AN1-Type Zinc Finger Protein 2A 3

External Ids for ZFAND2A Gene

Previous GeneCards Identifiers for ZFAND2A Gene

  • GC07M000966
  • GC07M001159
  • GC07M001103

Summaries for ZFAND2A Gene

GeneCards Summary for ZFAND2A Gene

ZFAND2A (Zinc Finger, AN1-Type Domain 2A) is a Protein Coding gene. An important paralog of this gene is ZFAND2B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFAND2A Gene

Genomics for ZFAND2A Gene

Regulatory Elements for ZFAND2A Gene

Genomic Location for ZFAND2A Gene

Start:
1,152,071 bp from pter
End:
1,160,759 bp from pter
Size:
8,689 bases
Orientation:
Minus strand

Genomic View for ZFAND2A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZFAND2A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFAND2A Gene

Proteins for ZFAND2A Gene

  • Protein details for ZFAND2A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N6M9-ZFN2A_HUMAN
    Recommended name:
    AN1-type zinc finger protein 2A
    Protein Accession:
    Q8N6M9
    Secondary Accessions:
    • A4D220

    Protein attributes for ZFAND2A Gene

    Size:
    145 amino acids
    Molecular mass:
    16477 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZFAND2A Gene

Proteomics data for ZFAND2A Gene at MOPED

Post-translational modifications for ZFAND2A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZFAND2A Gene

No data available for DME Specific Peptides for ZFAND2A Gene

Domains for ZFAND2A Gene

Gene Families for ZFAND2A Gene

HGNC:
  • ZFAND :Zinc fingers, AN1-type domain containing

Protein Domains for ZFAND2A Gene

Blocks:
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZFAND2A Gene

Graphical View of Domain Structure for InterPro Entry

Q8N6M9

UniProtKB/Swiss-Prot:

ZFN2A_HUMAN :
  • Q8N6M9
Similarity:
  • Contains 2 AN1-type zinc fingers.
genes like me logo Genes that share domains with ZFAND2A: view

Function for ZFAND2A Gene

Gene Ontology (GO) - Molecular Function for ZFAND2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZFAND2A: view

Phenotypes for ZFAND2A Gene

MGI mutant phenotypes for ZFAND2A:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with ZFAND2A: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZFAND2A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZFAND2A Gene

Localization for ZFAND2A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFAND2A Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZFAND2A Gene COMPARTMENTS Subcellular localization image for ZFAND2A gene
Compartment Confidence
nucleus 3
extracellular 2
cytosol 1

Gene Ontology (GO) - Cellular Components for ZFAND2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000502 proteasome complex IEA --
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with ZFAND2A: view

Pathways for ZFAND2A Gene

SuperPathways for ZFAND2A Gene

No Data Available

Interacting Proteins for ZFAND2A Gene

Gene Ontology (GO) - Biological Process for ZFAND2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA --
GO:0071243 cellular response to arsenic-containing substance IEA --
genes like me logo Genes that share ontologies with ZFAND2A: view

No data available for Pathways by source for ZFAND2A Gene

Transcripts for ZFAND2A Gene

Unigene Clusters for ZFAND2A Gene

Zinc finger, AN1-type domain 2A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZFAND2A

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZFAND2A Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6
SP1: - - - -
SP2: - - -
SP3: - -
SP4: -
SP5:

Relevant External Links for ZFAND2A Gene

GeneLoc Exon Structure for
ZFAND2A
ECgene alternative splicing isoforms for
ZFAND2A

Expression for ZFAND2A Gene

mRNA expression in normal human tissues for ZFAND2A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZFAND2A Gene Hs.648111

genes like me logo Genes that share expressions with ZFAND2A: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for ZFAND2A Gene

Orthologs for ZFAND2A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ZFAND2A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZFAND2A 35
  • 79.08 (n)
  • 70.34 (a)
ZFAND2A 36
  • 59 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZFAND2A 35
  • 86.57 (n)
  • 85.42 (a)
ZFAND2A 36
  • 71 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfand2a 35
  • 78.7 (n)
  • 77.08 (a)
Zfand2a 16
Zfand2a 36
  • 64 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfand2a 35
  • 79.17 (n)
  • 76.39 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 61 (a)
OneToMany
-- 36
  • 67 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia ZFAND2A 36
  • 52 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZFAND2A 35
  • 66.2 (n)
  • 62.94 (a)
ZFAND2A 36
  • 51 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii zfand2a 36
  • 33 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG12795 36
  • 30 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea aip-1 36
  • 30 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G57480 35
  • 46.17 (n)
  • 40.74 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5587 36
  • 27 (a)
OneToMany
Species with no ortholog for ZFAND2A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZFAND2A Gene

ENSEMBL:
Gene Tree for ZFAND2A (if available)
TreeFam:
Gene Tree for ZFAND2A (if available)

Paralogs for ZFAND2A Gene

Paralogs for ZFAND2A Gene

Selected SIMAP similar genes for ZFAND2A Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for ZFAND2A Gene

genes like me logo Genes that share paralogs with ZFAND2A: view

Variants for ZFAND2A Gene

Sequence variations from dbSNP and Humsavar for ZFAND2A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs1133116 -- 1,155,579(-) GATGT(G/T)CACGT synonymous-codon, reference
rs1133122 -- 1,152,936(-) GATGG(G/T)ACTAT utr-variant-3-prime
rs6945392 -- 1,157,029(+) CACCA(C/G)GGTCA intron-variant
rs6953538 -- 1,157,338(+) GTAAC(A/G)GATCA intron-variant
rs6970581 -- 1,152,452(+) TGGAC(A/G)CCAGA downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZFAND2A Gene

Variant ID Type Subtype PubMed ID
dgv7074n71 CNV Loss 21882294
nsv887128 CNV Loss 21882294
dgv7080n71 CNV Loss 21882294
nsv887141 CNV Loss 21882294
dgv7083n71 CNV Loss 21882294
dgv7087n71 CNV Loss 21882294
nsv482917 CNV Loss 15286789
nsv830876 CNV Loss 17160897
nsv508441 CNV Loss 20534489
nsv471182 CNV Loss 18288195
esv2499925 CNV Deletion 19546169
esv2110851 CNV Deletion 18987734
esv2733727 CNV Deletion 23290073
esv1295388 CNV Deletion 17803354
dgv2045e1 CNV Complex 17122850
dgv1109e201 CNV Deletion 23290073
esv2733730 CNV Deletion 23290073
esv1724460 CNV Deletion 17803354

Relevant External Links for ZFAND2A Gene

HapMap Linkage Disequilibrium report
ZFAND2A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZFAND2A Gene

Disorders for ZFAND2A Gene

Relevant External Links for ZFAND2A

Genetic Association Database (GAD)
ZFAND2A

No disorders were found for ZFAND2A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ZFAND2A Gene

Publications for ZFAND2A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. AIRAP, a new human heat shock gene regulated by heat shock factor 1. (PMID: 20185824) Rossi A. … Santoro M.G. (J. Biol. Chem. 2010) 2 3
  3. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ZFAND2A Gene

Sources for ZFAND2A Gene

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