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Aliases for ZFAND1 Gene

Aliases for ZFAND1 Gene

  • Zinc Finger, AN1-Type Domain 1 2 3

External Ids for ZFAND1 Gene

Summaries for ZFAND1 Gene

GeneCards Summary for ZFAND1 Gene

ZFAND1 (Zinc Finger, AN1-Type Domain 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZFAND1 Gene

Genomics for ZFAND1 Gene

Genomic Location for ZFAND1 Gene

Start:
81,701,331 bp from pter
End:
81,732,903 bp from pter
Size:
31,573 bases
Orientation:
Minus strand

Genomic View for ZFAND1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZFAND1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFAND1 Gene

Regulatory Elements for ZFAND1 Gene

Proteins for ZFAND1 Gene

  • Protein details for ZFAND1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TCF1-ZFAN1_HUMAN
    Recommended name:
    AN1-type zinc finger protein 1
    Protein Accession:
    Q8TCF1
    Secondary Accessions:
    • E5RIG0
    • E5RJ99
    • Q658R7
    • Q6IA32
    • Q6PGQ6
    • Q9H810

    Protein attributes for ZFAND1 Gene

    Size:
    268 amino acids
    Molecular mass:
    30787 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZFAND1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZFAND1 Gene

Proteomics data for ZFAND1 Gene at MOPED

Post-translational modifications for ZFAND1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZFAND1 Gene

Domains for ZFAND1 Gene

Gene Families for ZFAND1 Gene

HGNC:
  • ZFAND :Zinc fingers, AN1-type domain containing

Protein Domains for ZFAND1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

ZFAN1_HUMAN
Similarity:
  • Contains 2 AN1-type zinc fingers.:
    • Q8TCF1
genes like me logo Genes that share domains with ZFAND1: view

Function for ZFAND1 Gene

Gene Ontology (GO) - Molecular Function for ZFAND1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZFAND1: view

Phenotypes for ZFAND1 Gene

GenomeRNAi human phenotypes for ZFAND1:
genes like me logo Genes that share phenotypes with ZFAND1: view

miRNA for ZFAND1 Gene

miRTarBase miRNAs that target ZFAND1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZFAND1 Gene

Localization for ZFAND1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZFAND1 Gene COMPARTMENTS Subcellular localization image for ZFAND1 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 2
cytoskeleton 1

No data available for Gene Ontology (GO) - Cellular Components for ZFAND1 Gene

Pathways for ZFAND1 Gene

SuperPathways for ZFAND1 Gene

No Data Available

Interacting Proteins for ZFAND1 Gene

Gene Ontology (GO) - Biological Process for ZFAND1 Gene

None

No data available for Pathways by source for ZFAND1 Gene

Transcripts for ZFAND1 Gene

Unigene Clusters for ZFAND1 Gene

Zinc finger, AN1-type domain 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZFAND1 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b · 9c · 9d · 9e · 9f · 9g · 9h
SP1: - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - - -
SP4: -
SP5: - -
SP6: - -
SP7: - - - - -
SP8: - - - -
SP9: - - -
SP10: -
SP11: -

Relevant External Links for ZFAND1 Gene

GeneLoc Exon Structure for
ZFAND1
ECgene alternative splicing isoforms for
ZFAND1

Expression for ZFAND1 Gene

mRNA expression in normal human tissues for ZFAND1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZFAND1 Gene

SOURCE GeneReport for Unigene cluster for ZFAND1 Gene Hs.655453

genes like me logo Genes that share expressions with ZFAND1: view

Orthologs for ZFAND1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZFAND1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IMPA1 37
  • 99 (a)
OneToOne
ZFAND1 36
  • 99.38 (n)
  • 99.25 (a)
cow
(Bos Taurus)
Mammalia ZFAND1 37
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZFAND1 36
  • 91.79 (n)
  • 90.67 (a)
ZFAND1 37
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfand1 36
  • 84.2 (n)
  • 82.84 (a)
Zfand1 16
Zfand1 37
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZFAND1 37
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZFAND1 37
  • 74 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfand1 36
  • 82.96 (n)
  • 83.96 (a)
chicken
(Gallus gallus)
Aves ZFAND1 36
  • 74.53 (n)
  • 73.78 (a)
ZFAND1 37
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZFAND1 37
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.13002 36
zfand1 36
  • 67.04 (n)
  • 69.29 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.19087 36
zfand1 36
  • 61.42 (n)
  • 61.42 (a)
zfand1 37
  • 60 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR041C 36
  • 40.54 (n)
  • 29.81 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 37
  • 22 (a)
OneToOne
-- 39
YNL155W 36
  • 44.18 (n)
  • 31.13 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0D10978g 36
  • 40.59 (n)
  • 29.7 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU06586 36
  • 42.51 (n)
  • 36.44 (a)
Species with no ortholog for ZFAND1:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZFAND1 Gene

ENSEMBL:
Gene Tree for ZFAND1 (if available)
TreeFam:
Gene Tree for ZFAND1 (if available)

Paralogs for ZFAND1 Gene

Pseudogenes.org Pseudogenes for ZFAND1 Gene

genes like me logo Genes that share paralogs with ZFAND1: view

No data available for Paralogs for ZFAND1 Gene

Variants for ZFAND1 Gene

Sequence variations from dbSNP and Humsavar for ZFAND1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1052497 -- 81,701,996(-) TTTTT(G/T)TTTGT utr-variant-3-prime, nc-transcript-variant
rs2046786 -- 81,709,546(-) ACATA(A/C)ATGAA intron-variant
rs2046787 -- 81,709,428(-) TTTCT(A/G)TATAC intron-variant
rs2130263 -- 81,721,217(+) AAGCT(C/G)CCGGA intron-variant
rs2306917 -- 81,717,905(+) TGGAT(C/T)TTTAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZFAND1 Gene

Variant ID Type Subtype PubMed ID
nsv465721 CNV Gain 19166990
nsv831369 CNV Gain+Loss 17160897
esv2606227 CNV Deletion 19546169

Relevant External Links for ZFAND1 Gene

HapMap Linkage Disequilibrium report
ZFAND1

Disorders for ZFAND1 Gene

No disorders were found for ZFAND1 Gene.

No data available for UniProtKB/Swiss-Prot for ZFAND1 Gene

Publications for ZFAND1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A conserved protein with AN1 zinc finger and ubiquitin-like domains modulates Cdc48 (p97) function in the ubiquitin-proteasome pathway. (PMID: 24121501) SA!-Moura B. … Hochstrasser M. (J. Biol. Chem. 2013) 2 3
  4. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3
  5. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 4

Products for ZFAND1 Gene

Sources for ZFAND1 Gene

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