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Aliases for ZEB2-AS1 Gene

Subcategory (RNA class) for ZEB2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for ZEB2-AS1 Gene

  • ZEB2 Antisense RNA 1 2 3 5
  • ZEB2 Antisense RNA 1 (Non-Protein Coding) 2 3
  • ZEB2 Natural Antisense Transcript 2 3
  • ZEB2 Antisense RNA (Non-Protein Coding) 2
  • ZEB2NAT 3
  • ZEB2-AS 3
  • ZEB2AS 3

External Ids for ZEB2-AS1 Gene

Previous HGNC Symbols for ZEB2-AS1 Gene

  • ZEB2AS
  • ZEB2-AS

Previous GeneCards Identifiers for ZEB2-AS1 Gene

  • GC02U902264
  • GC02P145277

Summaries for ZEB2-AS1 Gene

Entrez Gene Summary for ZEB2-AS1 Gene

  • This gene produces a spliced long non-coding RNA which is a natural antisense transcript corresponding to the 5' UTR of zinc finger E-box binding homeobox 2 (ZEB2). It is thought that this transcript may be involved in the regulation of ZEB2 expression, and may play a role in the progression of bladder cancer. [provided by RefSeq, Aug 2015]

GeneCards Summary for ZEB2-AS1 Gene

ZEB2-AS1 (ZEB2 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Gene Wiki entry for ZEB2-AS1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZEB2-AS1 Gene

Genomics for ZEB2-AS1 Gene

Regulatory Elements for ZEB2-AS1 Gene

Enhancers for ZEB2-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G144579 3.1 VISTA Ensembl ENCODE dbSUPER 11.4 +64.1 64051 4.9 HDGF PKNOX1 CREB3L1 ARNT YBX1 ZNF766 FOS REST ZNF592 SMARCA4 ZEB2 ZEB2-AS1 GC02P144567 TEX41
GH02G144451 2.9 FANTOM5 Ensembl ENCODE dbSUPER 11.4 -60.5 -60544 12.0 PKNOX1 ATF1 ARNT FEZF1 ZNF2 TCF12 ZNF121 GATA2 FOS ZNF548 ZEB2 ZEB2-AS1 ENSG00000231758 GTDC1 ENSG00000283118 GC02P144494
GH02G144473 2.2 Ensembl ENCODE dbSUPER 11.7 -42.2 -42152 5.3 PKNOX1 TAL1 TEAD4 FEZF1 CEBPG TCF12 POLR2A ZNF652 CEBPB EP300 ZEB2 ZEB2-AS1 GC02P144494 ENSG00000283118
GH02G144469 2.3 Ensembl ENCODE dbSUPER 11.1 -47.8 -47760 3.4 PKNOX1 FEZF1 CHD7 ZNF2 RELA FOXM1 CTBP1 GLI2 ZSCAN5C ZNF600 ZEB2 ZEB2-AS1 GC02P144494 ENSG00000283118
GH02G144464 1.6 dbSUPER 11.4 -52.4 -52424 1.4 OSR2 POLR2A ZNF366 FEZF1 ZBTB33 ZNF843 ZXDB ZEB2-AS1 ZEB2 ENSG00000283118 GC02P144494
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZEB2-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZEB2-AS1 Gene

Chromosome:
2
Start:
144,518,097 bp from pter
End:
144,521,477 bp from pter
Size:
3,381 bases
Orientation:
Plus strand

Genomic View for ZEB2-AS1 Gene

Genes around ZEB2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZEB2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZEB2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZEB2-AS1 Gene

Proteins for ZEB2-AS1 Gene

Post-translational modifications for ZEB2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZEB2-AS1 Gene

Domains & Families for ZEB2-AS1 Gene

Gene Families for ZEB2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZEB2-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ZEB2-AS1 Gene

Function for ZEB2-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZEB2-AS1 Gene

Localization for ZEB2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZEB2-AS1 Gene

Pathways & Interactions for ZEB2-AS1 Gene

SuperPathways for ZEB2-AS1 Gene

No Data Available

Interacting Proteins for ZEB2-AS1 Gene

Gene Ontology (GO) - Biological Process for ZEB2-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZEB2-AS1 Gene

Transcripts for ZEB2-AS1 Gene

mRNA/cDNA for ZEB2-AS1 Gene

(1) Additional mRNA sequences :
(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZEB2-AS1 Gene

ZEB2 antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZEB2-AS1 Gene

No ASD Table

Relevant External Links for ZEB2-AS1 Gene

GeneLoc Exon Structure for
ZEB2-AS1
ECgene alternative splicing isoforms for
ZEB2-AS1

Expression for ZEB2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZEB2-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for ZEB2-AS1 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x6.4).

SOURCE GeneReport for Unigene cluster for ZEB2-AS1 Gene:

Hs.560789
genes like me logo Genes that share expression patterns with ZEB2-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZEB2-AS1 Gene

Orthologs for ZEB2-AS1 Gene

Evolution for ZEB2-AS1 Gene

ENSEMBL:
Gene Tree for ZEB2-AS1 (if available)
TreeFam:
Gene Tree for ZEB2-AS1 (if available)

No data available for Orthologs for ZEB2-AS1 Gene

Paralogs for ZEB2-AS1 Gene

No data available for Paralogs for ZEB2-AS1 Gene

Variants for ZEB2-AS1 Gene

Sequence variations from dbSNP and Humsavar for ZEB2-AS1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs886054898 Uncertain significance 144,520,074(-) GACAC(C/T)CTTGG nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs146048066 Benign 144,520,357(-) GAGAC(C/T)TCAAG intron-variant, nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs1000092738 -- 144,520,455(+) CTCCC(C/T)TCTCC intron-variant, upstream-variant-2KB
rs1000430932 -- 144,519,468(+) CCCGA(A/G)TTTGT intron-variant, upstream-variant-2KB
rs1000484780 -- 144,519,701(+) GGAGG(A/G)AAAAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZEB2-AS1 Gene

Variant ID Type Subtype PubMed ID
esv3592768 CNV loss 21293372

Relevant External Links for ZEB2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZEB2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZEB2-AS1 Gene

Disorders for ZEB2-AS1 Gene

Relevant External Links for ZEB2-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZEB2-AS1

No disorders were found for ZEB2-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZEB2-AS1 Gene

Publications for ZEB2-AS1 Gene

  1. TGFI^1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT. (PMID: 26152796) Zhuang J. … Guo H. (Sci Rep 2015) 2 3 64
  2. A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. (PMID: 18347095) Beltran M. … de Herreros A.G. (Genes Dev. 2008) 2 3 64
  3. Downregulation of ZEB2-AS1 decreased tumor growth and metastasis in hepatocellular carcinoma. (PMID: 27748842) Lan T. … Yuan Y. (Mol Med Rep 2016) 3 64

Products for ZEB2-AS1 Gene

Sources for ZEB2-AS1 Gene

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